J K McGuire

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Fatal hypermagnesemia in a child treated with megavitamin/megamineral therapy
    J K McGuire
    Division of Pediatric Pulmonary and Critical Care Medicine, Department of Pediatrics, Children s Memorial Hospital and Northwestern University Medical School, Chicago, Illinois, USA
    Pediatrics 105:E18. 2000
  2. ncbi Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium
    John K McGuire
    Department of Pediatrics, Washington University School of Medicine, St Louis, USA
    Am J Pathol 162:1831-43. 2003
  3. ncbi A risk assessment scoring system predicts survival following the Norwood procedure
    P A Checchia
    Division of Critical Care Medicine, Washington University School of Medicine, St Louis Children s Hospital, Campus Box 8116, St Louis, MO 63110, USA
    Pediatr Cardiol 27:62-6. 2006
  4. ncbi Matrilysin (MMP-7) expression in renal tubular damage: association with Wnt4
    Kameswaran Surendran
    Department of Pediatrics, Division of Biology and Biomedical Sciences, Washington University School of Medicine, and Saint Louis Children s Hospital, Missouri 63110, USA
    Kidney Int 65:2212-22. 2004
  5. ncbi Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity
    Peter Chen
    Center for Lung Biology, University of Washington School of Medicine, Seattle, WA 98109, USA
    Am J Pathol 172:1256-70. 2008
  6. ncbi Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa
    Sean Y Kassim
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Infect Immun 75:5640-50. 2007
  7. ncbi Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients
    Mei Swee
    Center for Lung Biology and Institute for Stem Cell and Regenerative Medicine and Department of Medicine, University of Washington, Seattle, WA 98109, USA
    J Leukoc Biol 83:1404-12. 2008

Collaborators

  • William C Parks
  • C Huddleston
  • DAVID MADTES
  • Mei Swee
  • Peter Chen
  • Sean Y Kassim
  • P A Checchia
  • Kameswaran Surendran
  • Ann J Chen
  • Robert C Hackman
  • Wei Yan
  • Phillip Liu
  • Carole L Wilson
  • Kyoung Hee Kim
  • Kurt Poindexter
  • Ying Wang
  • Roy A Black
  • Kyoung-Hee Kim
  • Sina A Gharib
  • Timothy P Birkland
  • Brigham H Mecham
  • N Daher
  • S Morrow
  • F Levy
  • Helen Liapis
  • Theodore C Simon

Detail Information

Publications7

  1. ncbi Fatal hypermagnesemia in a child treated with megavitamin/megamineral therapy
    J K McGuire
    Division of Pediatric Pulmonary and Critical Care Medicine, Department of Pediatrics, Children s Memorial Hospital and Northwestern University Medical School, Chicago, Illinois, USA
    Pediatrics 105:E18. 2000
    ....
  2. ncbi Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium
    John K McGuire
    Department of Pediatrics, Washington University School of Medicine, St Louis, USA
    Am J Pathol 162:1831-43. 2003
    ..These findings identify E-cadherin as a novel substrate for matrilysin and indicate that shedding of E-cadherin ectodomain is required for epithelial repair...
  3. ncbi A risk assessment scoring system predicts survival following the Norwood procedure
    P A Checchia
    Division of Critical Care Medicine, Washington University School of Medicine, St Louis Children s Hospital, Campus Box 8116, St Louis, MO 63110, USA
    Pediatr Cardiol 27:62-6. 2006
    ..This supports the conclusion that a specific population of HLHS patients may have a higher mortality risk independent of surgical technique and postoperative care based on factors that can be assessed preoperatively...
  4. ncbi Matrilysin (MMP-7) expression in renal tubular damage: association with Wnt4
    Kameswaran Surendran
    Department of Pediatrics, Division of Biology and Biomedical Sciences, Washington University School of Medicine, and Saint Louis Children s Hospital, Missouri 63110, USA
    Kidney Int 65:2212-22. 2004
    ..Matrilysin, a secreted matrix metalloproteinase and target gene of Wnt signaling, functions in epithelial repair and host defense, but no role in renal injury has been described...
  5. ncbi Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity
    Peter Chen
    Center for Lung Biology, University of Washington School of Medicine, Seattle, WA 98109, USA
    Am J Pathol 172:1256-70. 2008
    ....
  6. ncbi Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa
    Sean Y Kassim
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Infect Immun 75:5640-50. 2007
    ..Our results demonstrate discrete roles for these MMPs in regulating epithelial responses to Pseudomonas infection and show that a global genomics strategy can be used to assess MMP function...
  7. ncbi Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients
    Mei Swee
    Center for Lung Biology and Institute for Stem Cell and Regenerative Medicine and Department of Medicine, University of Washington, Seattle, WA 98109, USA
    J Leukoc Biol 83:1404-12. 2008
    ..On one hand, it promotes re-epithelialization, but it also controls the transepithelial influx of neutrophils, which if excessive, can lead to tissue damage...