J B McGill

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Clinical safety of the selective PKC-beta inhibitor, ruboxistaurin
    Janet B McGill
    Washington University School of Medicine, 660 S Euclid, Campus Box 8127, St Louis, MO 63110, USA
    Expert Opin Drug Saf 5:835-45. 2006
  2. pmc Optimal use of beta-blockers in high-risk hypertension: a guide to dosing equivalence
    Janet B McGill
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Vasc Health Risk Manag 6:363-72. 2010
  3. doi request reprint Progress and controversies: treating obesity and insulin resistance in the context of hypertension
    Janet B McGill
    Washington University School of Medicine, Division of Endocrinology, Metabolism and Lipid Research, St Louis, MO 63110, USA
    J Clin Hypertens (Greenwich) 11:36-41. 2009
  4. ncbi request reprint Kidney Early Evaluation Program (KEEP). Findings from a community screening program
    Janet B McGill
    Division of Endocrinology, Metabolism, and Lipid Research, Washington University, St Louis, MO, USA
    Diabetes Educ 30:196-8, 200-2, 206. 2004
  5. ncbi request reprint beta-blocker use and diabetes symptom score: results from the GEMINI study
    J B McGill
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Diabetes Obes Metab 9:408-17. 2007
  6. ncbi request reprint Telmisartan plus hydrochlorothiazide versus telmisartan or hydrochlorothiazide monotherapy in patients with mild to moderate hypertension: a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial
    J B McGill
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Ther 23:833-50. 2001
  7. doi request reprint Liraglutide: effects beyond glycaemic control in diabetes treatment
    J B McGill
    Division of Endocrinology, Metabolism and Lipid Research, Washington University in St Louis, St Louis, MO 63110, USA
    Int J Clin Pract Suppl 64:28-34. 2010
  8. ncbi request reprint Combination treatment with telmisartan and hydrochlorothiazide in black patients with mild to moderate hypertension
    J B McGill
    Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    Clin Cardiol 24:66-72. 2001
  9. ncbi request reprint Effects of nortriptyline on depression and glycemic control in diabetes: results of a double-blind, placebo-controlled trial
    P J Lustman
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychosom Med 59:241-50. 1997
  10. ncbi request reprint Effect of ruboxistaurin on urinary transforming growth factor-beta in patients with diabetic nephropathy and type 2 diabetes
    Richard E Gilbert
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 30:995-6. 2007

Collaborators

Detail Information

Publications46

  1. ncbi request reprint Clinical safety of the selective PKC-beta inhibitor, ruboxistaurin
    Janet B McGill
    Washington University School of Medicine, 660 S Euclid, Campus Box 8127, St Louis, MO 63110, USA
    Expert Opin Drug Saf 5:835-45. 2006
    ..In controlled, randomised clinical trials, RBX had an adverse event profile comparable to placebo, and was well tolerated...
  2. pmc Optimal use of beta-blockers in high-risk hypertension: a guide to dosing equivalence
    Janet B McGill
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Vasc Health Risk Manag 6:363-72. 2010
    ..beta-blockers with proven efficacy, once-daily dosing, and lower side effect profiles may become instrumental in the treatment of hypertensive diabetic and nondiabetic patients...
  3. doi request reprint Progress and controversies: treating obesity and insulin resistance in the context of hypertension
    Janet B McGill
    Washington University School of Medicine, Division of Endocrinology, Metabolism and Lipid Research, St Louis, MO 63110, USA
    J Clin Hypertens (Greenwich) 11:36-41. 2009
    ..Awareness of these pathophysiologic interrelations and their implications for treatment are likely to be of increasing importance for successful blood pressure management...
  4. ncbi request reprint Kidney Early Evaluation Program (KEEP). Findings from a community screening program
    Janet B McGill
    Division of Endocrinology, Metabolism, and Lipid Research, Washington University, St Louis, MO, USA
    Diabetes Educ 30:196-8, 200-2, 206. 2004
    ..The Kidney Early Evaluation Program (KEEP), which was started in 1997, aims to identify persons at risk for chronic kidney disease (CKD) and encourage at-risk persons to seek evaluation and management from a healthcare provider...
  5. ncbi request reprint beta-blocker use and diabetes symptom score: results from the GEMINI study
    J B McGill
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Diabetes Obes Metab 9:408-17. 2007
    ..In this paper, we report the results of a prespecified secondary analysis of GEMINI that sought to determine the effect of these two beta-blockers on commonly reported symptoms...
  6. ncbi request reprint Telmisartan plus hydrochlorothiazide versus telmisartan or hydrochlorothiazide monotherapy in patients with mild to moderate hypertension: a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial
    J B McGill
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Ther 23:833-50. 2001
    ..Recent surveys reveal continuing deficiencies in the awareness, treatment, and control of hypertension. In many cases, failure to achieve blood pressure targets may be attributable to the use of antihypertensive monotherapy...
  7. doi request reprint Liraglutide: effects beyond glycaemic control in diabetes treatment
    J B McGill
    Division of Endocrinology, Metabolism and Lipid Research, Washington University in St Louis, St Louis, MO 63110, USA
    Int J Clin Pract Suppl 64:28-34. 2010
    ..To review the non-glycaemic effects of liraglutide, including potential improvements in body weight, systolic blood pressure (SBP) and pancreatic beta-cell function...
  8. ncbi request reprint Combination treatment with telmisartan and hydrochlorothiazide in black patients with mild to moderate hypertension
    J B McGill
    Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    Clin Cardiol 24:66-72. 2001
    ..CONCLUSIONS: Telmisartan 80 mg combined with HCTZ 12.5 mg is effective and well tolerated in black patients with mild to moderate hypertension, providing greater antihypertensive activity than the corresponding monotherapies...
  9. ncbi request reprint Effects of nortriptyline on depression and glycemic control in diabetes: results of a double-blind, placebo-controlled trial
    P J Lustman
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychosom Med 59:241-50. 1997
    ..This investigation evaluated the effects of nortriptyline on depression and glycemic control to see whether depression in diabetes is treatable and whether restoring mental health contributes to improved medical outcome...
  10. ncbi request reprint Effect of ruboxistaurin on urinary transforming growth factor-beta in patients with diabetic nephropathy and type 2 diabetes
    Richard E Gilbert
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 30:995-6. 2007
  11. ncbi request reprint Efficacy of sertraline in prevention of depression recurrence in older versus younger adults with diabetes
    Monique M Williams
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Diabetes Care 30:801-6. 2007
    ..A secondary analysis was performed to assess this effect in younger and older subsets of patients...
  12. ncbi request reprint Paradoxical increase in ventricular torsion and systolic torsion rate in type I diabetic patients under tight glycemic control
    Jina Chung
    Cardiovascular Magnetic Resonance Laboratories, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Am Coll Cardiol 47:384-90. 2006
    ..This study sought to characterize the early features of diabetic cardiomyopathy by magnetic resonance imaging (MRI) tagging...
  13. ncbi request reprint Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial
    Lori M B Laffel
    Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Diabetes Technol Ther 9:254-64. 2007
    ....
  14. ncbi request reprint Independent components of chronic kidney disease as a cardiovascular risk state: results from the Kidney Early Evaluation Program (KEEP)
    Peter A McCullough
    Division of Cardiology, William Beaumont Hospital, Royal Oak, MI 48073, USA
    Arch Intern Med 167:1122-9. 2007
    ..We hypothesized that each of these chronic kidney disease-related measures would have an independent relationship with CVD...
  15. ncbi request reprint Body weight changes with beta-blocker use: results from GEMINI
    Franz H Messerli
    St Luke s Roosevelt Hospital Center, New York City, NY 10019, USA
    Am J Med 120:610-5. 2007
    ....
  16. ncbi request reprint Protein kinase C beta inhibition: the promise for treatment of diabetic nephropathy
    Pamela W Anderson
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46234, USA
    Curr Opin Nephrol Hypertens 16:397-402. 2007
    ..Additional therapeutic agents are therefore urgently needed...
  17. ncbi request reprint Kidney outcomes in long-term studies of ruboxistaurin for diabetic eye disease
    Katherine R Tuttle
    Providence Medical Research Center and University of Washington School of Medicine, Spokane, Washington, USA
    Clin J Am Soc Nephrol 2:631-6. 2007
    ..In contrast, in a trial of patients with diabetic retinopathy, investigators reported the adverse event "diabetic nephropathy" more frequently in patients who received RBX...
  18. ncbi request reprint Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy
    Mark E Williams
    Harvard Medical School, Joslin Diabetes Center, Boston, MA 02215, USA
    Am J Nephrol 27:605-14. 2007
    ..We report the results of safety/tolerability studies in patients with overt nephropathy and type 1/type 2 diabetes treated with pyridoxamine, a broad inhibitor of advanced glycation...
  19. ncbi request reprint Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial
    Jackson T Wright
    Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Hypertens (Greenwich) 9:842-9. 2007
    ..The use of carvedilol compared with metoprolol did not effect glycemic control...
  20. ncbi request reprint The decrease in microalbuminuria with carvedilol therapy is not enhanced by concurrent use of a statin
    David S H Bell
    Endocr Pract 13:808-9. 2007
  21. ncbi request reprint Anemia and the role of erythropoietin in diabetes
    Janet B McGill
    Washington University School of Medicine, St Louis, MO, USA
    J Diabetes Complications 20:262-72. 2006
    ..Promptly diagnosing and treating anemia in patients with diabetes may result in an improved quality of life and decreased morbidity and mortality...
  22. ncbi request reprint Alterations in left ventricular structure and function in type-1 diabetics: a focus on left atrial contribution to function
    Linda R Peterson
    Cardiovascular Division, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Soc Echocardiogr 19:749-55. 2006
    ....
  23. ncbi request reprint Sertraline for prevention of depression recurrence in diabetes mellitus: a randomized, double-blind, placebo-controlled trial
    Patrick J Lustman
    Department of Veterans Affairs Medical Center, St Louis, MO, USA
    Arch Gen Psychiatry 63:521-9. 2006
    ..In patients with diabetes mellitus, depression is a prevalent and recurrent problem that adversely affects the medical prognosis...
  24. ncbi request reprint Depression and coronary heart disease in women with diabetes
    Ray E Clouse
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Psychosom Med 65:376-83. 2003
    ..Depression predicts onset of and poor outcome from CHD in nondiabetic populations. We hypothesized that the doubled rates of depression in female diabetic patients could help explain the high prevalence of CHD in women with diabetes...
  25. ncbi request reprint Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes
    V Lee Grotz
    Medical and Nutritional Affairs, McNeil Nutritionals, New Bruswick, NJ 08903 2400, USA
    J Am Diet Assoc 103:1607-12. 2003
    ..To investigate the effect of 3-months' daily administration of high doses of sucralose, a non-nutritive sweetener, on glycemic control in subjects with type 2 diabetes...
  26. ncbi request reprint Circulating 1,5-anhydroglucitol levels in adult patients with diabetes reflect longitudinal changes of glycemia: a U.S. trial of the GlycoMark assay
    Janet B McGill
    Washington University School of Medicine, St Louis, Missouri, USA
    Diabetes Care 27:1859-65. 2004
    ....
  27. ncbi request reprint Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial
    George L Bakris
    Department of Preventive Medicine, Rush University Medical Center, Chicago, Ill, USA
    JAMA 292:2227-36. 2004
    ..Beta-blockers have been shown to decrease cardiovascular risk in patients with hypertension and type 2 diabetes mellitus (DM); however, some components of the metabolic syndrome are worsened by some beta-blockers...
  28. ncbi request reprint Rationale--Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT): evolving the management of cardiovascular risk in patients with chronic kidney disease
    T Christian H Mix
    Department of Development and Medical Affairs, Amgen Inc, Thousand Oaks, Calif, USA
    Am Heart J 149:408-13. 2005
    ....
  29. ncbi request reprint The effect of ruboxistaurin on nephropathy in type 2 diabetes
    Katherine R Tuttle
    Research Department, The Heart Institute and Sacred Heart Medical Center, Spokane, WA 99204 2340, USA
    Diabetes Care 28:2686-90. 2005
    ..Ruboxistaurin selectively inhibits protein kinase C-beta and ameliorates kidney disease in animal models of diabetes. The purpose of this study was to evaluate the effects of ruboxistaurin on diabetic nephropathy in humans...
  30. ncbi request reprint Differential effects of beta-blockers on albuminuria in patients with type 2 diabetes
    George L Bakris
    Rush University Medical Center, Chicago, IL 60612, USA
    Hypertension 46:1309-15. 2005
    ..These differences cannot be explained by effects on blood pressure or alpha1-antagonism but may relate to antioxidant properties of carvedilol...
  31. ncbi request reprint Gastrointestinal absorption and plasma kinetics of soy Delta(5)-phytosterols and phytostanols in humans
    Richard E Ostlund
    Division of Endocrinology, Diabetes and Metabolism, Washington University School of Medicine, Missouri 63017, USA
    Am J Physiol Endocrinol Metab 282:E911-6. 2002
    ..We conclude that the efficiency of phytosterol absorption is lower than what was reported previously and is critically dependent on the structure of both sterol nucleus and side chain...
  32. ncbi request reprint Fat-free foods supplemented with soy stanol-lecithin powder reduce cholesterol absorption and LDL cholesterol
    Curtis A Spilburg
    Lifeline Technologies, Chesterfield, MO 63017, USA
    J Am Diet Assoc 103:577-81. 2003
    ..The objective of this work was to show that fat-free, lecithin-formulated soy stanols lower cholesterol absorption and serum LDL cholesterol...
  33. ncbi request reprint How to make exercise counseling more effective: lessons from rural America
    Karrisa A Weidinger
    Prevention Research Center and Department of Community Health, Saint Louis University School of Public Health, St Louis, MO USA
    J Fam Pract 57:394-402. 2008
    ..However, the prevalence and effectiveness of physician counseling is unknown in rural populations that are at increased risk for chronic diseases...
  34. ncbi request reprint Inpatient glycemic control on the vascular surgery service
    Brenda M Theilen
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    Endocr Pract 14:185-91. 2008
    ..To describe a structured inpatient insulin management protocol and order set for glycemic control on a vascular surgery service...
  35. ncbi request reprint Effect of LDL cholesterol and treatment with losartan on end-stage renal disease in the RENAAL study
    Andrew M Tershakovec
    Merck Research Laboratories, Merck and Co, Inc, Upper Gwynedd, Pennsylvania, USA
    Diabetes Care 31:445-7. 2008
    ..LDL cholesterol lowering was associated with a lower risk of ESRD; however, this seemed to be largely an association with the reduction in albuminuria...
  36. ncbi request reprint The changing landscape of type 2 diabetes: the role of incretin-based therapies in managed care outcomes
    Curtis Triplitt
    Texas Diabetes Institute, San Antonio, TX 78207, USA
    J Manag Care Pharm 13:S2-16; quiz S17. 2007
    ..Newer classes of antihyperglycemic agents, the incretin-based therapies, have the potential to improve goal achievement...
  37. ncbi request reprint Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus
    Susan B Racette
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Metabolism 51:169-74. 2002
    ..However, TZD therapy did not affect whole-body glycerol R(a), possibly because of upregulation of lipoprotein lipase action on plasma triglycerides...
  38. ncbi request reprint How the diabetic eye loses vision
    Jaime A Davidson
    Division of Endocrinology, University of Texas, Southwestern Medical School, Dallas, Texas 75230, USA
    Endocrine 32:107-16. 2007
    ..Many experts and associations recommend that patients with diabetes have an yearly, thorough, dilated eye exam. This manuscript describes the case history of a patient with diabetes and vision loss...
  39. ncbi request reprint Serum 1,5-anhydroglucitol (GlycoMark ): a short-term glycemic marker
    John B Buse
    Divisions of Endocrinology and of General Medicine and Clinical Epidemiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
    Diabetes Technol Ther 5:355-63. 2003
    ..The behavior of this analyte is different from all others used in the management of diabetes, creating potential opportunities for its use in clinical practice...
  40. ncbi request reprint Continuous subcutaneous insulin infusion and multiple daily injection therapy are equally effective in type 2 diabetes: a randomized, parallel-group, 24-week study
    Philip Raskin
    University of Texas, Southwestern Medical Center, Dallas, Texas 75390 8858, USA
    Diabetes Care 26:2598-603. 2003
    ..Compare the efficacy, safety, and patient satisfaction of continuous subcutaneous insulin infusion (CSII) therapy with multiple daily injection (MDI) therapy for patients with type 2 diabetes...
  41. ncbi request reprint Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study
    William F Keane
    Merck and Co, Inc, Whitehouse Station, New Jersey, USA
    Clin J Am Soc Nephrol 1:761-7. 2006
    ..Future trials with a similar patient population and outcomes measures should consider adjusting analyses for baseline risk factors...
  42. ncbi request reprint Anxiety and poor glycemic control: a meta-analytic review of the literature
    Ryan J Anderson
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Int J Psychiatry Med 32:235-47. 2002
    ..To determine whether anxiety is associated with poor glycemic control in adults with type 1 or type 2 diabetes...
  43. ncbi request reprint The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus
    Muthayyah Srinivasan
    Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    J Am Coll Cardiol 46:42-8. 2005
    ..The objective of this study was to determine the impact of insulin and glucose on myocardial vasodilator function in patients with type 1 diabetes mellitus (T1DM)...
  44. ncbi request reprint Epidemiology of obesity and chronic kidney disease
    Will R Ross
    Washington University School of Medicine, St Louis, MO 63110, USA
    Adv Chronic Kidney Dis 13:325-35. 2006
    ..Intervention strategies may need to target prenatal care through the elderly to combat this problematic epidemic...
  45. ncbi request reprint Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus
    Pilar Herrero
    Division of Radiological Sciences, Edward Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Am Coll Cardiol 47:598-604. 2006
    ..The purpose of this study was to determine if myocardial fatty acid utilization (MFAU) and myocardial fatty acid oxidation (MFAO) are increased in diabetic patients...
  46. ncbi request reprint Psychosocial factors in patients with chronic kidney disease
    Steven D Weisbord
    Adv Chronic Kidney Dis 14:316-8. 2007