Ai Jun Li

Summary

Affiliation: Washington State University
Country: USA

Publications

  1. pmc Hindbrain catecholamine neurons control rapid switching of metabolic substrate use during glucoprivation in male rats
    Ai Jun Li
    Department of Integrative Physiology and Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 7620
    Endocrinology 154:4570-9. 2013
  2. pmc Leptin-sensitive neurons in the arcuate nuclei contribute to endogenous feeding rhythms
    Ai Jun Li
    Dept of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State Univ, Pullman, WA 99164 6520, USA
    Am J Physiol Regul Integr Comp Physiol 302:R1313-26. 2012
  3. pmc Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington, USA
    Diabetes 60:436-42. 2011
  4. pmc Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington 99164 6520, USA
    J Neurosci 29:280-7. 2009
  5. ncbi Differential responsiveness of dopamine-beta-hydroxylase gene expression to glucoprivation in different catecholamine cell groups
    Ai Jun Li
    Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State University, Pullman, 99164 6520, USA
    Endocrinology 147:3428-34. 2006
  6. ncbi Functional expression of neuropeptide Y receptors in human neuroblastoma cells
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington 99164 6520, USA
    Regul Pept 129:119-24. 2005
  7. ncbi Glucoprivation increases expression of neuropeptide Y mRNA in hindbrain neurons that innervate the hypothalamus
    Ai Jun Li
    Programs in Neuroscience, Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164 6520, USA
    Eur J Neurosci 19:2147-54. 2004
  8. pmc Hyperphagia and obesity produced by arcuate injection of NPY-saporin do not require upregulation of lateral hypothalamic orexigenic peptide genes
    Ai Jun Li
    Washington State University, Pullman, WA 99164 6520, USA
    Peptides 29:1732-9. 2008
  9. ncbi Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake
    Kishor Bugarith
    Programs in Neuroscience, Washington State University, Pullman, Washington 99164 6520, USA
    Endocrinology 146:1179-91. 2005
  10. pmc Leptin-sensitive neurons in the arcuate nucleus integrate activity and temperature circadian rhythms and anticipatory responses to food restriction
    Michael F Wiater
    Programs in Neuroscience, Washington State University, Pullman, Washington
    Am J Physiol Regul Integr Comp Physiol 305:R949-60. 2013

Collaborators

  • Robert C Speth
  • Jun Fang
  • Huan Zhao
  • Sue Ritter
  • Thu T Dinh
  • Rebecca A Darling
  • Michael F Wiater
  • Kishor Bugarith
  • Steven M Simasko
  • Seigo Suzuki
  • Dallas Kinch
  • Heiko T Jansen
  • Qing Wang
  • Toru Imamura
  • Mitsushi Ikemoto

Detail Information

Publications17

  1. pmc Hindbrain catecholamine neurons control rapid switching of metabolic substrate use during glucoprivation in male rats
    Ai Jun Li
    Department of Integrative Physiology and Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 7620
    Endocrinology 154:4570-9. 2013
    ..Sustained elevation of basal RER in DSAP rats indicates that catecholamine neurons also influence metabolic functions that conserve glucose under basal conditions. ..
  2. pmc Leptin-sensitive neurons in the arcuate nuclei contribute to endogenous feeding rhythms
    Ai Jun Li
    Dept of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State Univ, Pullman, WA 99164 6520, USA
    Am J Physiol Regul Integr Comp Physiol 302:R1313-26. 2012
    ....
  3. pmc Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington, USA
    Diabetes 60:436-42. 2011
    ..To examine the role of AMP-activated protein kinase (AMPK) in the control of glucoprivic feeding by hindbrain catecholamine neurons...
  4. pmc Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington 99164 6520, USA
    J Neurosci 29:280-7. 2009
    ..These results suggest that catecholamines and NPY act conjointly to control glucoprivic feeding and that the crucial NPY/catecholamine coexpressing neurons are concentrated in the A1/C1 cell group...
  5. ncbi Differential responsiveness of dopamine-beta-hydroxylase gene expression to glucoprivation in different catecholamine cell groups
    Ai Jun Li
    Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State University, Pullman, 99164 6520, USA
    Endocrinology 147:3428-34. 2006
    ..The pattern of 2DG-induced gene expression indicates that the ventrolateral medulla contains the vast majority of catecholamine neurons responsive to glucoprivation...
  6. ncbi Functional expression of neuropeptide Y receptors in human neuroblastoma cells
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington 99164 6520, USA
    Regul Pept 129:119-24. 2005
    ..Since NPY activates MAPK via different subtypes of NPY receptors, results suggest that endogenously expressed NPY may control proliferation of these cells through a paracrine/autocrine mechanism...
  7. ncbi Glucoprivation increases expression of neuropeptide Y mRNA in hindbrain neurons that innervate the hypothalamus
    Ai Jun Li
    Programs in Neuroscience, Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164 6520, USA
    Eur J Neurosci 19:2147-54. 2004
    ..The responsiveness of hindbrain NPY neurons to glucose deficit suggests that these neurons participate in glucoprivic feeding or other glucoregulatory responses...
  8. pmc Hyperphagia and obesity produced by arcuate injection of NPY-saporin do not require upregulation of lateral hypothalamic orexigenic peptide genes
    Ai Jun Li
    Washington State University, Pullman, WA 99164 6520, USA
    Peptides 29:1732-9. 2008
    ..The source of the seemingly unregulated stimulatory drive for feeding in these animals has not been identified, but may be associated with hindbrain or endocrine mechanisms...
  9. ncbi Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake
    Kishor Bugarith
    Programs in Neuroscience, Washington State University, Pullman, Washington 99164 6520, USA
    Endocrinology 146:1179-91. 2005
    ..Thus, NPY-SAP destroyed NPY receptor-expressing neurons in the ARC and selectively disrupted controls of feeding dependent on those neurons but did not disrupt peptidergic or metabolic controls dependent upon circuitry outside the BMH...
  10. pmc Leptin-sensitive neurons in the arcuate nucleus integrate activity and temperature circadian rhythms and anticipatory responses to food restriction
    Michael F Wiater
    Programs in Neuroscience, Washington State University, Pullman, Washington
    Am J Physiol Regul Integr Comp Physiol 305:R949-60. 2013
    ....
  11. pmc Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons
    Ai Jun Li
    Programs in Neuroscience, Washington State University, Pullman, Washington
    Am J Physiol Regul Integr Comp Physiol 306:R257-64. 2014
    ....
  12. pmc Minireview: The value of looking backward: the essential role of the hindbrain in counterregulatory responses to glucose deficit
    Sue Ritter
    Department of Veterinary and Comparative Anatomy, Pharmacology, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 6520, USA
    Endocrinology 152:4019-32. 2011
    ..Nevertheless, the accumulated evidence demonstrates that hindbrain glucose sensors and NE/E neurons are essential players in triggering counterregulatory responses to emergencies of glucose deficit...
  13. ncbi Hindbrain catecholamine neurons control multiple glucoregulatory responses
    Sue Ritter
    Programs in Neuroscience, Washington State University, Pullman, WA 99164 6520, USA
    Physiol Behav 89:490-500. 2006
    ..Specific catecholamine phenotypes may mediate the individual components of the overall response. Glucoreceptive control of these neurons resides within the hindbrain...
  14. ncbi Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors
    Rebecca A Darling
    Program in Neuroscience, Washington State University, Pullman, Washington
    Am J Physiol Regul Integr Comp Physiol 307:R35-43. 2014
    ..Thus, we propose that MA's nonmetabolic actions on GPR40 membrane receptors, expressed by multiple peripheral tissues in addition to the vagus nerve, may contribute to or mediate MA-induced stimulation of feeding. ..
  15. ncbi Expression of tenascin-C long isoforms is induced in the hypothalamus by FGF-1
    Seigo Suzuki
    Gene Discovery Research Center, National Institute of Advanced Industrial Science and Technology AIST, AIST Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Neuroreport 13:1041-5. 2002
    ..Quantitative analysis by real time PCR revealed that this induction was transient and dose-dependent. Specific modulation of hypothalamic neuron-glial interactions by tenascin-C may mediate FGF-1-induced feeding suppression...
  16. ncbi [Effects of Nomega-nitro-L-arginine on photoreceptor apoptosis in inherited retinal degeneration of RCS rats]
    Ai Jun Li
    Department of Ophthalmology, Peking University Third Hospital, Peking University Eye Center, Beijing 100083, China
    Beijing Da Xue Xue Bao 36:353-6. 2004
    ..To investigate inducible nitric oxide synthase(iNOS) activity of retina and the effects of N(omega)-nitro-L-arginine(N-Arg) on photoreceptor apoptosis in inherited retinal degeneration of Royal College of Surgeons (RCS) rats...
  17. ncbi Fibroblast growth factor-2 increases functional excitatory synapses on hippocampal neurons
    Ai Jun Li
    Age Dimension Research Centre, National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Eur J Neurosci 16:1313-24. 2002
    ..These results indicate that: (i) FGF-2 increases excitatory synapses on hippocampal neurons by activating MAPK activity through FGF receptors; and (ii) synapses formed in FGF-2-treated culture are capable of cycling vesicles...