J S Lewis

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Workshop on the production, application and clinical translation of ''non-standard'' PET nuclides: a meeting report
    J S Lewis
    Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Q J Nucl Med Mol Imaging 52:101-6. 2008
  2. ncbi request reprint Comparative dosimetry of copper-64 and yttrium-90-labeled somatostatin analogs in a tumor-bearing rat model
    J S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA
    Cancer Biother Radiopharm 15:593-604. 2000
  3. ncbi request reprint A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 49:1171-82. 2001
  4. pmc Spindle cell carcinomas of the head and neck rarely harbor transcriptionally-active human papillomavirus
    R F Watson
    Pathology and Immunology, Washington University School of Medicine, Campus Box 8118, 660 S Euclid Ave, St Louis, MO 63110, USA
    Head Neck Pathol 7:250-7. 2013
  5. ncbi request reprint Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): effect of changes in tissue oxygenation
    J S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA
    J Nucl Med 42:655-61. 2001
  6. ncbi request reprint Toxicity and dosimetry of (177)Lu-DOTA-Y3-octreotate in a rat model
    J S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
    Int J Cancer 94:873-7. 2001
  7. ncbi request reprint Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells
    A Obata
    Biomedical Imaging Research Center, Fukui Medical University, Matsuoka, Japan
    Ann Nucl Med 15:499-504. 2001

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Workshop on the production, application and clinical translation of ''non-standard'' PET nuclides: a meeting report
    J S Lewis
    Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Q J Nucl Med Mol Imaging 52:101-6. 2008
    ..Also, the translation of these nuclides to the clinic, perhaps the most important goal of this work is discussed in this introductory article...
  2. ncbi request reprint Comparative dosimetry of copper-64 and yttrium-90-labeled somatostatin analogs in a tumor-bearing rat model
    J S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA
    Cancer Biother Radiopharm 15:593-604. 2000
    ..90Y-DOTA-Y3-OC and 64Cu-DOTA-Y3-OC were comparable with respect to their tumor-to-normal tissue dose ratios, while 90Y-DOTA-Y3-TATE appeared to have distinct advantages over 64Cu-DOTA-Y3-TATE...
  3. ncbi request reprint A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 49:1171-82. 2001
    ....
  4. pmc Spindle cell carcinomas of the head and neck rarely harbor transcriptionally-active human papillomavirus
    R F Watson
    Pathology and Immunology, Washington University School of Medicine, Campus Box 8118, 660 S Euclid Ave, St Louis, MO 63110, USA
    Head Neck Pathol 7:250-7. 2013
    ..Although the number of cases is too small for any definitive conclusions, for the rare HPV positive spindle cell carcinoma cases, positive viral status does not appear to confer any prognostic benefit...
  5. ncbi request reprint Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): effect of changes in tissue oxygenation
    J S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA
    J Nucl Med 42:655-61. 2001
    ..Therefore, the possible use of Cu-ATSM PET as a prognostic indicator in the management of cancer is further validated...
  6. ncbi request reprint Toxicity and dosimetry of (177)Lu-DOTA-Y3-octreotate in a rat model
    J S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
    Int J Cancer 94:873-7. 2001
    ..The absorbed dose to the rat CA20948 tumor was estimated to be 336 rad/mCi (91 mGy/MBq). These data demonstrate that (177)Lu-DOTA-Y3-TATE is an effective targeted radiotherapy agent at levels that show minimal toxicity in this rat model...
  7. ncbi request reprint Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells
    A Obata
    Biomedical Imaging Research Center, Fukui Medical University, Matsuoka, Japan
    Ann Nucl Med 15:499-504. 2001
    ..This enzymatic reduction was enhanced by the induction of hypoxia. Radiocopper labeled Cu-ATSM provides useful information for the detection of hypoxia as well as the microsomal bioreductive enzyme expression in tumor...