J G Laing

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Connexin45 interacts with zonula occludens-1 and connexin43 in osteoblastic cells
    J G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 276:23051-5. 2001
  2. ncbi request reprint Connexin45 interacts with zonula occludens-1 in osteoblastic cells
    J G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cell Commun Adhes 8:209-12. 2001
  3. ncbi request reprint ZO-1 alters the plasma membrane localization and function of Cx43 in osteoblastic cells
    James G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Cell Sci 118:2167-76. 2005
  4. ncbi request reprint Association with ZO-1 correlates with plasma membrane partitioning in truncated connexin45 mutants
    J G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Membr Biol 207:45-53. 2005
  5. ncbi request reprint Diminished zonula occludens-1 expression in the failing human heart
    James G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Cardiovasc Pathol 16:159-64. 2007
  6. ncbi request reprint Connexin expression and turnover : implications for cardiac excitability
    J E Saffitz
    Departments of Pathology and Medicine and the Center for Cardiovascular Research, Washington University, St Louis, MO 63110, USA
    Circ Res 86:723-8. 2000
  7. ncbi request reprint Redistribution of connexin45 in gap junctions of connexin43-deficient hearts
    Carolyn M Johnson
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Cardiovasc Res 53:921-35. 2002
  8. ncbi request reprint Pathways for degradation of connexins and gap junctions
    Viviana M Berthoud
    Department of Pediatrics, Section of Hematology Oncology, University of Chicago, 5841 S Maryland Ave, MC 4060, Chicago, IL 60637, USA
    Cardiovasc Res 62:256-67. 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Connexin45 interacts with zonula occludens-1 and connexin43 in osteoblastic cells
    J G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 276:23051-5. 2001
    ....
  2. ncbi request reprint Connexin45 interacts with zonula occludens-1 in osteoblastic cells
    J G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cell Commun Adhes 8:209-12. 2001
    ..Furthermore we found that ZO-1 could bind to peptides derived from the carboxyl terminal of Cx45 that had been covalently bound to an agarose resin. These data suggests that Cx45 and ZO-1 directly interact in ROS/Cx45 cells...
  3. ncbi request reprint ZO-1 alters the plasma membrane localization and function of Cx43 in osteoblastic cells
    James G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Cell Sci 118:2167-76. 2005
    ..They suggest that ZO-1-mediated delivery of Cx43 from a lipid raft domain to gap junctional plaques may be an important regulatory step in gap junction formation...
  4. ncbi request reprint Association with ZO-1 correlates with plasma membrane partitioning in truncated connexin45 mutants
    J G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Membr Biol 207:45-53. 2005
    ....
  5. ncbi request reprint Diminished zonula occludens-1 expression in the failing human heart
    James G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Cardiovasc Pathol 16:159-64. 2007
    ..Here, we determined whether expression of ZO-1 is altered in patients with heart failure...
  6. ncbi request reprint Connexin expression and turnover : implications for cardiac excitability
    J E Saffitz
    Departments of Pathology and Medicine and the Center for Cardiovascular Research, Washington University, St Louis, MO 63110, USA
    Circ Res 86:723-8. 2000
    ..Regulation of connexin degradation may be an important mechanism for adjusting intercellular coupling in the heart under normal and pathophysiological conditions...
  7. ncbi request reprint Redistribution of connexin45 in gap junctions of connexin43-deficient hearts
    Carolyn M Johnson
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Cardiovasc Res 53:921-35. 2002
    ..The present study was undertaken to determine (1) whether expression of Cx45 is upregulated and (2) whether gap junction structure and distribution are altered in Cx43-deficient mice...
  8. ncbi request reprint Pathways for degradation of connexins and gap junctions
    Viviana M Berthoud
    Department of Pediatrics, Section of Hematology Oncology, University of Chicago, 5841 S Maryland Ave, MC 4060, Chicago, IL 60637, USA
    Cardiovasc Res 62:256-67. 2004
    ..Degradation of gap junction plaques is proteasome-dependent in some cell types. Degradation may be regulated by ubiquitinylation, phosphorylation, or polypeptide domains that act as sorting signals...