Marin Kollef

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. doi request reprint Clinical implications for patients treated inappropriately for community-acquired pneumonia in the emergency department
    Scott T Micek
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8052, St, Louis, MO 63110, USA
    BMC Infect Dis 14:61. 2014
  2. doi request reprint Ventilator-associated complications, including infection-related complications: the way forward
    Marin H Kollef
    Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Clin 29:33-50. 2013
  3. doi request reprint Economic impact of ventilator-associated pneumonia in a large matched cohort
    Marin H Kollef
    Washington University School of Medicine, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 33:250-6. 2012
  4. pmc Cost and mortality prediction using polymerase chain reaction pathogen detection in sepsis: evidence from three observational trials
    Lutz E Lehmann
    Department of Anesthesiology and Pain Therapy, University Hospital Bern, Inselspital, Freiburgstrasse, CH 3010 Bern, Switzerland
    Crit Care 14:R186. 2010
  5. pmc CD4+ lymphocyte adenosine triphosphate determination in sepsis: a cohort study
    Kevin L Lawrence
    Department of Medicine, Washington University in St, Louis School of Medicine, 660 South Euclid, Campus Box 8052, St Louis, Missouri 63110, USA
    Crit Care 14:R110. 2010
  6. pmc Bench-to-bedside review: Understanding the impact of resistance and virulence factors on methicillin-resistant Staphylococcus aureus infections in the intensive care unit
    Lee P Skrupky
    Department of Pharmacy, Barnes Jewish Hospital, St Louis, MO 63110, USA
    Crit Care 13:222. 2009
  7. pmc Candidemia on presentation to the hospital: development and validation of a risk score
    Andrew F Shorr
    Pulmonary and Critical Care Medicine Service, Washington Hospital Center, Washington, DC 20010, USA
    Crit Care 13:R156. 2009
  8. pmc Inappropriate empiric antifungal therapy for candidemia in the ICU and hospital resource utilization: a retrospective cohort study
    Marya D Zilberberg
    EviMed Research Group, LLC, PO Box 303, Goshen, MA 01032, USA
    BMC Infect Dis 10:150. 2010
  9. ncbi request reprint Severe hospital-acquired pneumonia: a review for clinicians
    John Dallas
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, Campus Box 8052, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Curr Infect Dis Rep 11:349-56. 2009
  10. doi request reprint Epidemiology, microbiology and outcomes of healthcare-associated and community-acquired bacteremia: a multicenter cohort study
    Marin H Kollef
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Infect 62:130-5. 2011

Collaborators

Detail Information

Publications30

  1. doi request reprint Clinical implications for patients treated inappropriately for community-acquired pneumonia in the emergency department
    Scott T Micek
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8052, St, Louis, MO 63110, USA
    BMC Infect Dis 14:61. 2014
    ..Increasingly, antibiotic resistant bacteria have been identified as causative pathogens in patients treated for CAP, especially in patients with healthcare exposure risk factors...
  2. doi request reprint Ventilator-associated complications, including infection-related complications: the way forward
    Marin H Kollef
    Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Clin 29:33-50. 2013
    ..The use of evidence-based bundles targeting the reduction of VACs, as well as the conduct of prospective studies showing that VACs are preventable complications, are reasonable first-steps in addressing this important clinical problem...
  3. doi request reprint Economic impact of ventilator-associated pneumonia in a large matched cohort
    Marin H Kollef
    Washington University School of Medicine, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 33:250-6. 2012
    ..To evaluate the economic impact of ventilator-associated pneumonia (VAP) on length of stay and hospital costs. Design. Retrospective matched cohort study...
  4. pmc Cost and mortality prediction using polymerase chain reaction pathogen detection in sepsis: evidence from three observational trials
    Lutz E Lehmann
    Department of Anesthesiology and Pain Therapy, University Hospital Bern, Inselspital, Freiburgstrasse, CH 3010 Bern, Switzerland
    Crit Care 14:R186. 2010
    ..We analyze the impact on medical outcomes and healthcare costs if improved adequacy of antimicrobial therapy is achieved by providing immediate coverage after positive PCR reports...
  5. pmc CD4+ lymphocyte adenosine triphosphate determination in sepsis: a cohort study
    Kevin L Lawrence
    Department of Medicine, Washington University in St, Louis School of Medicine, 660 South Euclid, Campus Box 8052, St Louis, Missouri 63110, USA
    Crit Care 14:R110. 2010
    ..Our objective was to describe a cohort of patients with sepsis in terms of their measured immune status...
  6. pmc Bench-to-bedside review: Understanding the impact of resistance and virulence factors on methicillin-resistant Staphylococcus aureus infections in the intensive care unit
    Lee P Skrupky
    Department of Pharmacy, Barnes Jewish Hospital, St Louis, MO 63110, USA
    Crit Care 13:222. 2009
    ..Although vancomycin has long been considered a first-line therapy for serious MRSA infections, multiple concerns with this agent have opened the door for existing and investigational agents demonstrating efficacy in this role...
  7. pmc Candidemia on presentation to the hospital: development and validation of a risk score
    Andrew F Shorr
    Pulmonary and Critical Care Medicine Service, Washington Hospital Center, Washington, DC 20010, USA
    Crit Care 13:R156. 2009
    ..Candidemia results in substantial morbidity and mortality, especially if initial antifungal therapy is delayed or is inappropriate; however, candidemia is difficult to diagnose because of its nonspecific presentation...
  8. pmc Inappropriate empiric antifungal therapy for candidemia in the ICU and hospital resource utilization: a retrospective cohort study
    Marya D Zilberberg
    EviMed Research Group, LLC, PO Box 303, Goshen, MA 01032, USA
    BMC Infect Dis 10:150. 2010
    ..Inappropriate antifungal therapy (IAT) is known to increase a patient's risk for death. We hypothesized that in an ICU cohort it would also adversely affect resource utilization...
  9. ncbi request reprint Severe hospital-acquired pneumonia: a review for clinicians
    John Dallas
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, Campus Box 8052, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Curr Infect Dis Rep 11:349-56. 2009
    ..A large body of scientific literature about HAP now exists. This article summarizes the current state of knowledge concerning severe HAP with an emphasis on recent advances in its diagnosis, treatment, and prevention...
  10. doi request reprint Epidemiology, microbiology and outcomes of healthcare-associated and community-acquired bacteremia: a multicenter cohort study
    Marin H Kollef
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Infect 62:130-5. 2011
    ..Regarding bloodstream infection (BSI), little data exist differentiating healthcare-associated bacteremia (HCAB) from community-acquired bacteremia (CAB). We studied the epidemiology and outcomes associated with HCAB...
  11. doi request reprint Prevention of nosocomial pneumonia in the intensive care unit: beyond the use of bundles
    Marin H Kollef
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63021, USA
    Surg Infect (Larchmt) 12:211-20. 2011
    ....
  12. doi request reprint Healthcare-associated pneumonia: approach to management
    Andrew Labelle
    Division of Pulmonary and Critical Care, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Chest Med 32:507-15. 2011
    ..Ability to predict infection with MDR organisms varies, and the relative frequency of MDR organisms varies by geographic region. Initial treatment is broad-spectrum empiric antibiotics...
  13. pmc Appraising contemporary strategies to combat multidrug resistant gram-negative bacterial infections--proceedings and data from the Gram-Negative Resistance Summit
    Marin H Kollef
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, 660 South Euclid Ave, Campus Box 8052, St Louis, MO 63110, USA
    Clin Infect Dis 53:S33-55; quiz S56-8. 2011
    ..The results then were compared with the same survey completed by 138 infectious disease and critical care physicians and are the basis of this article...
  14. pmc Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators
    Marin H Kollef
    Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, Missouri 63110, USA
    Crit Care 14:R84. 2010
    ....
  15. doi request reprint Prevention of ventilator-associated pneumonia or ventilator-associated complications: a worthy, yet challenging, goal
    Marin H Kollef
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Crit Care Med 40:271-7. 2012
    ..The use of evidence-based bundles targeting ventilator-associated pneumonia seems to be a reasonable first step in addressing this important clinical problem...
  16. doi request reprint Using protocols to improve patient outcomes in the intensive care unit: focus on mechanical ventilation and sepsis
    Marin H Kollef
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Semin Respir Crit Care Med 31:19-30. 2010
    ..This review focuses on the use of protocols in the ICU setting and how they can best be utilized to improve patient outcomes...
  17. doi request reprint The determinants of hospital mortality among patients with septic shock receiving appropriate initial antibiotic treatment*
    Andrew Labelle
    Division of Pulmonary and Critical Care, Washington University School of Medicine, St Louis, MO, USA
    Crit Care Med 40:2016-21. 2012
    ..To identify the determinants of hospital mortality among patients with septic shock receiving appropriate initial antibiotic treatment...
  18. pmc Risk factors for acute adverse events during ultrasound-guided central venous cannulation in the emergency department
    Daniel Theodoro
    Washington University School of Medicine, St Louis, MO, USA
    Acad Emerg Med 17:1055-61. 2010
    ..Despite the ability to visualize the needle and anatomy, adverse events still occur. The authors hypothesized that the technique has limitations among certain patients and clinical scenarios...
  19. pmc Clostridium difficile in the ICU: the struggle continues
    Linda D Bobo
    Adult Infectious Diseases Division, University School of Medicine, St Louis, MO, USA
    Chest 140:1643-53. 2011
    ....
  20. ncbi request reprint Effect of kinetic therapy on pulmonary complications
    Thomas Ahrens
    Barnes Jewish Hospital, St Louis, MO, USA
    Am J Crit Care 13:376-83. 2004
    ..Kinetic therapy (systematic mechanical rotation of patients with 40 degree turns) may improve pulmonary function more than the improvement in function achieved via the standard of care (turning patients every 2 hours)...
  21. pmc Toward a two-tier clinical warning system for hospitalized patients
    Gregory Hackmann
    Department of Computer Science and Engineering, Washington University, St Louis, MO, USA
    AMIA Annu Symp Proc 2011:511-9. 2011
    ..Preliminary study of an early warning system component and a wireless clinical monitoring system component demonstrate the feasibility of this two-tiered approach...
  22. ncbi request reprint A cost-benefit analysis of gown use in controlling vancomycin-resistant Enterococcus transmission: is it worth the price?
    Laura A Puzniak
    Department of Community Health, Saint Louis University School of Public Health, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 25:418-24. 2004
    ..To determine the net benefit and costs associated with gown use in preventing transmission of vancomycin-resistant Enterococcus (VRE)...
  23. doi request reprint Septic shock attributed to Candida infection: importance of empiric therapy and source control
    Marin Kollef
    Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 54:1739-46. 2012
    ..However, septic shock attributed to Candida infection and its determinants of outcome have not been previously evaluated in a large patient population...
  24. ncbi request reprint A randomized double-blind trial of iseganan in prevention of ventilator-associated pneumonia
    Marin Kollef
    Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8052, St Louis, MO 63110, USA
    Am J Respir Crit Care Med 173:91-7. 2006
    ..The drug has shown little resistance in vitro and to be safe and well tolerated in 800 patients with cancer treated for up to 6 wk...
  25. ncbi request reprint Use of hypochlorite solution to decrease rates of Clostridium difficile-associated diarrhea
    Kathleen M McMullen
    Barnes Jewish Hospital, St Louis, MO 63108, USA
    Infect Control Hosp Epidemiol 28:205-7. 2007
    ..One unit instituted enhanced environmental cleaning with a hypochlorite solution in all rooms, whereas the other unit used hypochlorite solution only in rooms of patients with CDAD. The CDAD rates decreased in both units...
  26. pmc A descriptive comparison of ultrasound-guided central venous cannulation of the internal jugular vein to landmark-based subclavian vein cannulation
    Daniel Theodoro
    Division of Emergency Medicine, Washington University School of Medicine, St Louis, MO, USA
    Acad Emerg Med 17:416-22. 2010
    ..The purpose of this study was to describe adverse event rates among operators using the USIJ approach, and the landmark SC vein approach without US...
  27. doi request reprint SMART approaches for reducing nosocomial infections in the ICU
    Marin Kollef
    Washington University School of Medicine, MO 63110, USA
    Chest 134:447-56. 2008
    ..Make objectives time bound; set dates for collecting baseline and periodic data, and a completion date for evaluating the success of the intervention...
  28. ncbi request reprint Improving family communications at the end of life: implications for length of stay in the intensive care unit and resource use
    Tom Ahrens
    Barnes Jewish Hospital, St Louis, MO, USA
    Am J Crit Care 12:317-23; discussion 324. 2003
    ..This model has not been tested for its effect on patients' outcomes and resource utilization...
  29. ncbi request reprint Appropriate empirical antibacterial therapy for nosocomial infections: getting it right the first time
    Marin Kollef
    Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Drugs 63:2157-68. 2003
    ..Antibacterial resistance is minimised by narrowing the antibacterial regimen once the pathogens and their susceptibility profiles are determined, and by employing the shortest course of therapy clinically acceptable...
  30. doi request reprint Ventilator-associated tracheobronchitis in a mixed surgical and medical ICU population
    John Dallas
    Department of Pulmonary and Critical Care Medicine, Washington University School of Medicine, and Department of Pharmacy, Barnes Jewish Hospital, 660 S Euclid Ave, Campus Box 8052, St Louis, MO 63110, USA
    Chest 139:513-8. 2011
    ..The purpose of this prospective cohort study was to further characterize VAT in terms of incidence, etiology, and impact on patient outcomes...