M H Kollef

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Chest 115:462-74. 1999
  2. ncbi Epidemiology and risk factors for nosocomial pneumonia. Emphasis on prevention
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Chest Med 20:653-70. 1999
  3. ncbi The effect of respiratory therapist-initiated treatment protocols on patient outcomes and resource utilization
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
    Chest 117:467-75. 2000
  4. ncbi Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 31:S131-8. 2000
  5. ncbi Opinion: the clinical use of selective digestive decontamination
    M H Kollef
    Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Crit Care 4:327-32. 2000
  6. ncbi Acute respiratory failure: a gender-based outcomes analysis
    M H Kollef
    Pulmonary and Critical Care Division, Washington University School of Medicine, Campus Box 8052, 660 S Euclid Ave, St Louis, MO 63110, USA
    J Gend Specif Med 1:24-30. 1998
  7. ncbi The impact of nosocomial infections on patient outcomes following cardiac surgery
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care, Washington University School of Medicine, St Louis, MO 63110, USA
    Chest 112:666-75. 1997
  8. ncbi The influence of mini-BAL cultures on patient outcomes: implications for the antibiotic management of ventilator-associated pneumonia
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Chest 113:412-20. 1998
  9. ncbi Experience with a clinical guideline for the treatment of ventilator-associated pneumonia
    E H Ibrahim
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA
    Crit Care Med 29:1109-15. 2001
  10. ncbi Antibiotic resistance in the intensive care unit
    M H Kollef
    Campus Box 8052, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Ann Intern Med 134:298-314. 2001

Collaborators

Detail Information

Publications17

  1. ncbi Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Chest 115:462-74. 1999
    ..To evaluate the relationship between inadequate antimicrobial treatment of infections (both community-acquired and nosocomial infections) and hospital mortality for patients requiring ICU admission...
  2. ncbi Epidemiology and risk factors for nosocomial pneumonia. Emphasis on prevention
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Chest Med 20:653-70. 1999
    ..To be successful, such quality improvement programs must be embraced at the institutional level. Only in this way can hospitals hope to successfully reduce their rates of VAP and sustain or improve upon those efforts over time...
  3. ncbi The effect of respiratory therapist-initiated treatment protocols on patient outcomes and resource utilization
    M H Kollef
    Department of Internal Medicine, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
    Chest 117:467-75. 2000
    ..Physicians frequently prescribe respiratory treatments to hospitalized patients, but the influence of such treatments on clinical outcomes is difficult to assess...
  4. ncbi Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 31:S131-8. 2000
    ..Further study evaluating the use of antibiotic practice guidelines and strategies to reduce inadequate treatment is necessary to determine their impact on patient outcomes...
  5. ncbi Opinion: the clinical use of selective digestive decontamination
    M H Kollef
    Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Crit Care 4:327-32. 2000
    ..Prolonged decontamination of the aerodigestive tract with topical antimicrobials does not appear to influence outcome, and should not be routinely employed...
  6. ncbi Acute respiratory failure: a gender-based outcomes analysis
    M H Kollef
    Pulmonary and Critical Care Division, Washington University School of Medicine, Campus Box 8052, 660 S Euclid Ave, St Louis, MO 63110, USA
    J Gend Specif Med 1:24-30. 1998
    ..To determine the influence of gender on patient outcomes and the delivery of medical care during mechanical ventilation for acute respiratory failure...
  7. ncbi The impact of nosocomial infections on patient outcomes following cardiac surgery
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care, Washington University School of Medicine, St Louis, MO 63110, USA
    Chest 112:666-75. 1997
    ..To evaluate the relationship between nosocomial infections and clinical outcomes following cardiac surgery, and to identify risk factors for the development of nosocomial infections in this patient population...
  8. ncbi The influence of mini-BAL cultures on patient outcomes: implications for the antibiotic management of ventilator-associated pneumonia
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Chest 113:412-20. 1998
    ..To determine the influence of mini-BAL culture results on subsequent changes in antibiotic therapy and patient outcomes...
  9. ncbi Experience with a clinical guideline for the treatment of ventilator-associated pneumonia
    E H Ibrahim
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA
    Crit Care Med 29:1109-15. 2001
    ..These findings suggest that similar types of guidelines employing local microbiological data can be used to improve overall antibiotic utilization for the treatment of ventilator-associated pneumonia...
  10. ncbi Antibiotic resistance in the intensive care unit
    M H Kollef
    Campus Box 8052, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Ann Intern Med 134:298-314. 2001
    ..Careful, focused attention to this problem at the local ICU level, using a multidisciplinary approach, will have the greatest likelihood of limiting the development and dissemination of antibiotic-resistant infections...
  11. ncbi The occurrence of ventilator-associated pneumonia in a community hospital: risk factors and clinical outcomes
    E H Ibrahim
    Pulmonary and Critical Care Medicine Division, Department of Internal Medicine, Washington University School of Medicine, Barnes-Jewish Hospital, Saint Louis, MO 63110, USA
    Chest 120:555-61. 2001
    ..More importantly, they should cooperate in the development of local multidisciplinary strategies aimed at the prevention of VAP and other nosocomial infections...
  12. ncbi Optimizing antibiotic therapy in the intensive care unit setting
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Division, Washington University School of Medicine, Barnes Jewish Hospital, Campus Box 8052, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Crit Care 5:189-95. 2001
    ..Only in this way can the impact of interventions aimed at improving antibiotic use (e.g. antibiotic rotation, de-escalation therapy) be evaluated at the local level...
  13. ncbi Is there a role for antibiotic cycling in the intensive care unit?
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, MO, USA
    Crit Care Med 29:N135-42. 2001
    ..The main goal of cycling is to allow resistance rates for specific antibiotics to decrease, or at least remain stable, when their use is periodically eliminated from the intensive care unit...
  14. ncbi Using protocols to improve the outcomes of mechanically ventilated patients. Focus on weaning and sedation
    E H Ibrahim
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Washington University School of Medicine, Barnes-Jewish Hospital, Saint Louis, Missouri, USA
    Crit Care Clin 17:989-1001. 2001
    ..Protocols are one method for potentially reducing those delays and ensuring that medical care is administered in a more standardized and efficient manner...
  15. ncbi A randomized clinical trial of continuous aspiration of subglottic secretions in cardiac surgery patients
    M H Kollef
    Department of Internal Medicine, Pulmonary and Critical Care Division, Washington University School of Medicine, St Louis, MO, USA
    Chest 116:1339-46. 1999
    ..To determine whether the application of continuous aspiration of subglottic secretions (CASS) is associated with a decreased incidence of ventilator-associated pneumonia (VAP)...
  16. ncbi The impact of the introduction of a rapid D-dimer assay on the diagnostic evaluation of suspected pulmonary embolism
    N M Goldstein
    Campus Box 8052, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Intern Med 161:567-71. 2001
    ..Although this hypothesis is anticipated to decrease the use of ventilation-perfusion (VQ) scans and other diagnostic tests for PE, it has not been tested in a "real-world" environment...
  17. ncbi Antibiotic management of ventilator-associated pneumonia due to antibiotic-resistant gram-positive bacterial infection
    M H Kollef
    Washington University School of Medicine, Campus Box 8052, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Eur J Clin Microbiol Infect Dis 24:794-803. 2005
    ..Studies are needed to define the optimal choice of antibiotic for pneumonias caused by this organism, and these choices will need to be balanced with the need to minimize the emergence of resistance...