Adam Kibel

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Prostate-specific antigen density predicts adverse pathology and increased risk of biochemical failure
    Mohamed H Radwan
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 69:1121-7. 2007
  2. ncbi request reprint Methylation and mutational analysis of p27(kip1) in prostate carcinoma
    A S Kibel
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63105, USA
    Prostate 48:248-53. 2001
  3. ncbi request reprint Mutational analysis of ETV6 in prostate carcinoma
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Prostate 52:305-10. 2002
  4. ncbi request reprint An interdisciplinary approach to treating prostate cancer
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA
    Urology 65:13-8. 2005
  5. ncbi request reprint Expression mapping at 12p12-13 in advanced prostate carcinoma
    Adam S Kibel
    Department of Surgery, Division of Urology, Washington University School of Medicine, 4960 Children s Place, St Louis, MO 63110, USA
    Int J Cancer 109:668-72. 2004
  6. ncbi request reprint Xq27-28 deletions in prostate carcinoma
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Genes Chromosomes Cancer 37:381-8. 2003
  7. ncbi request reprint Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma
    Ferrin C Noonan-Wheeler
    Department of Surgery, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    Prostate 66:49-56. 2006
  8. ncbi request reprint CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma
    Adam S Kibel
    Departments of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer Res 63:2033-6. 2003
  9. ncbi request reprint 11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse
    Nobuyuki Oyama
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Boulevard, St Louis, MO 63110, USA
    J Nucl Med 44:549-55. 2003
  10. ncbi request reprint Prostate cancer: screening, diagnosis and management in 2007
    Robert L Grubb
    Washington University School of Medicine, St Louis, USA
    Mo Med 104:408-13; quiz 413-4. 2007

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Prostate-specific antigen density predicts adverse pathology and increased risk of biochemical failure
    Mohamed H Radwan
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 69:1121-7. 2007
    ....
  2. ncbi request reprint Methylation and mutational analysis of p27(kip1) in prostate carcinoma
    A S Kibel
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63105, USA
    Prostate 48:248-53. 2001
    ..Herein, we examine metastatic prostate tumors, xenografts, and cell lines for gene inactivation via mutational inactivation or promoter hypermethylation...
  3. ncbi request reprint Mutational analysis of ETV6 in prostate carcinoma
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Prostate 52:305-10. 2002
    ..Therefore, we decided to analyze 43 prostate cell lines, xenografts, and metastatic foci for inactivating mutations...
  4. ncbi request reprint An interdisciplinary approach to treating prostate cancer
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA
    Urology 65:13-8. 2005
    ..Referral to a medical oncologist for a full discussion of treatment options is in the best interest of patients with HRPC, and patients at high-risk for treatment failure should be encouraged to consider clinical trial enrollment...
  5. ncbi request reprint Expression mapping at 12p12-13 in advanced prostate carcinoma
    Adam S Kibel
    Department of Surgery, Division of Urology, Washington University School of Medicine, 4960 Children s Place, St Louis, MO 63110, USA
    Int J Cancer 109:668-72. 2004
    ..DUSP16, FLJ10298 and BCLG were significantly downregulated in both clinical tumors and cultured prostate cancer tissue, indicating that one or all may be critical to initiation or progression of prostate carcinoma...
  6. ncbi request reprint Xq27-28 deletions in prostate carcinoma
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Genes Chromosomes Cancer 37:381-8. 2003
    ..These data clearly indicate that deletions do occur within the HPCX locus in a subset of sporadic prostate cancers and therefore raises the possibility that the gene at this locus may prove to play a role in sporadic disease...
  7. ncbi request reprint Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma
    Ferrin C Noonan-Wheeler
    Department of Surgery, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    Prostate 66:49-56. 2006
    ..Herein, we examine patients with metastatic disease to determine if an association exists between HPC SNPs and unambiguously significant prostate cancer...
  8. ncbi request reprint CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma
    Adam S Kibel
    Departments of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer Res 63:2033-6. 2003
    ..Analysis of CDKN1A and/or CDKN1B genotypes may prove useful in determining which patients are at risk for developing advanced prostate carcinoma and therefore would gain the most from aggressive screening, prophylaxis, and/or treatment...
  9. ncbi request reprint 11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse
    Nobuyuki Oyama
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Boulevard, St Louis, MO 63110, USA
    J Nucl Med 44:549-55. 2003
    ..We also compared the reliability of AC PET in detecting recurrent prostate cancer with that of PET with (18)F-FDG...
  10. ncbi request reprint Prostate cancer: screening, diagnosis and management in 2007
    Robert L Grubb
    Washington University School of Medicine, St Louis, USA
    Mo Med 104:408-13; quiz 413-4. 2007
    ..Recently, docetaxel has been added to standard androgen ablation as an effective treatment for advanced prostate cancer...
  11. doi request reprint The Gleason score of tumor at the margin in radical prostatectomy is predictive of biochemical recurrence
    Dengfeng Cao
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Surg Pathol 34:994-1001. 2010
    ..Reporting the Gleason score of the tumor at the margin can improve predictive accuracy of biochemical recurrence. We advocate reporting the Gleason score of tumor at the margin in radical prostatectomy...
  12. doi request reprint Association between polymorphisms in cell cycle genes and advanced prostate carcinoma
    Adam S Kibel
    Department of Surgery, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    Prostate 68:1179-86. 2008
    ..Herein, we explored the role of SNPs in cell cycle genes to determine if they were associated with advanced PCa...
  13. pmc Impact of comorbidity on overall survival in patients surgically treated for renal cell carcinoma
    David A Berger
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63105, USA
    Urology 72:359-63. 2008
    ..Because patients with renal cell carcinoma often have other medical conditions, we explored the effect of preexisting medical disease on survival after radical and partial nephrectomy...
  14. doi request reprint Prospective study of [18F]fluorodeoxyglucose positron emission tomography/computed tomography for staging of muscle-invasive bladder carcinoma
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, 4960 Children s Place, Box 8242, St Louis, MO 63105, USA
    J Clin Oncol 27:4314-20. 2009
    ..Herein, we report a prospective study of positron emission tomography/computed tomography (PET/CT) with [(18)F]fluorodeoxyglucose (FDG) in patients undergoing radical cystectomy for cT2-3N0M0 urothelial carcinoma of the bladder...
  15. doi request reprint Effect of reclassification on the incidence of benign and malignant renal tumors
    Ted A Skolarus
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine and Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    J Urol 183:455-8. 2010
    ..To further investigate the impact of histological reclassification we reexamined all excised renal masses using the 2004 WHO criteria and compared this histological classification to the prior criteria...
  16. pmc Risk of urinary incontinence following prostatectomy: the role of physical activity and obesity
    Kathleen Y Wolin
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 183:629-33. 2010
    ..We evaluated the association of obesity and lack of physical activity with urinary incontinence in a sample of men who had undergone radical prostatectomy...
  17. doi request reprint Percent microscopic tumor necrosis and survival after curative surgery for renal cell carcinoma
    Matthew D Katz
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 183:909-14. 2010
    ..We determined whether a correlation exists between the amount (not just the presence/absence) of tumor necrosis, and metastasis-free, disease specific and overall survival after surgery for renal cell carcinoma...
  18. pmc Prognostic impact of comorbidity in patients with bladder cancer
    Ifeanyichukwu I Megwalu
    Division of Urology, Washington University School of Medicine, St Louis, MO, USA
    Eur Urol 53:581-9. 2008
    ..To determine the impact of comorbidity on survival of bladder cancer patients...
  19. ncbi request reprint Adjuvant weekly docetaxel for patients with high risk prostate cancer after radical prostatectomy: a multi-institutional pilot study
    Adam S Kibel
    Siteman Cancer Center, Washington University School of Medicine, St Louis, Missouri 63105, USA
    J Urol 177:1777-81. 2007
    ..Patients with adverse pathological features are at high risk for recurrence following radical prostatectomy. To improve outcomes in this population we performed a phase II study of adjuvant docetaxel in these high risk patients...
  20. ncbi request reprint Patterns of multiple recurrences of superficial (Ta/T1) transitional cell carcinoma of bladder and effects of clinicopathologic and biochemical factors
    Yan Yan
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer 95:1239-46. 2002
    ....
  21. ncbi request reprint Single nucleotide polymorphisms: early diagnosis and risk assessment in genitourinary malignancy
    Adam S Kibel
    Department of Surgery Division of Urology, Washington University School of Medicine, St Louis, MO 63110, USA
    Urol Oncol 24:224-30. 2006
    ..Here, we review the rationale for studying polymorphic variants in urologic malignancies, prior studies in the field, and future avenues of research...
  22. doi request reprint Percentage of high-grade carcinoma as a prognostic indicator in patients with renal cell carcinoma
    Maria F Serrano
    Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer 113:477-83. 2008
    ..However, to the authors' knowledge, the prognostic significance of the amount of high-grade renal cell carcinoma has not been previously analyzed...
  23. doi request reprint High-risk localized prostate cancer: role of radical prostatectomy
    Robert L Grubb
    Division of Urology, Department of Surgery, Washington University in St Louis, St Louis, MO 63105, USA
    Curr Opin Urol 20:204-10. 2010
    ....
  24. ncbi request reprint Surgical treatment of renal neoplasia: evolving toward a laparoscopic standard of care
    Sam B Bhayani
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 62:821-6. 2003
    ..To determine the extent to which laparoscopy has replaced open surgery for renal malignancy...
  25. doi request reprint Evaluation of a novel precision template-guided biopsy system for detecting prostate cancer
    Ifeanyichukwu I Megwalu
    Division of Urology, Washington University School of Medicine, St Louis, MO 63105, USA
    BJU Int 102:546-50. 2008
    ....
  26. ncbi request reprint Transitional cell carcinoma of the renal pelvis associated with hypercalcemia in a patient with autosomal dominant polycystic kidney disease
    Robert L Grubb
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    Urology 63:778-80. 2004
    ..The hypercalcemia had not recurred, and she was without evidence of disease recurrence at 36 months. This case is unique in that we did not find any previously reported cases of TCC associated with ADPKD and hypercalcemia...
  27. ncbi request reprint Minimally invasive approaches to localized prostate carcinoma
    Robert L Grubb
    Division of Urology, Washington University School of Medicine, St Louis, MO 63110, USA
    Hematol Oncol Clin North Am 20:879-95. 2006
    ..They attempt to use nonsurgical methods to treat prostate cancer with the hope of providing oncologic control comparable to surgery and radiation while minimizing morbidity...
  28. pmc Association of CASP8 D302H polymorphism with reduced risk of aggressive prostate carcinoma
    Jessica Lubahn
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    Prostate 70:646-53. 2010
    ..As such, genetic variants in apoptosis genes are potential markers of aggressive PCa. Recent work in breast carcinoma has implicated the histidine variant of CASP8 D302H (rs1045485) as a protective risk allele...
  29. ncbi request reprint The distribution of histological subtypes of renal tumors by decade of life using the 2004 WHO classification
    Ted A Skolarus
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine and Barnes Jewish Hospital, St Louis, Missouri, USA
    J Urol 179:439-43; discussion 443-4. 2008
    ..We reviewed all partial and radical nephrectomy specimens at Barnes-Jewish Hospital to determine if the distribution of renal tumor histological subtypes varies by decade of life using the new scheme...
  30. ncbi request reprint Trends in nephron-sparing surgery for renal neoplasia
    Sam B Bhayani
    Department of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 68:732-6. 2006
    ..To determine the extent that laparoscopy has replaced open surgery for nephron-sparing surgery in a mature laparoscopic environment...
  31. ncbi request reprint Comparison of hand assisted and standard laparoscopic radical nephroureterectomy for the management of localized transitional cell carcinoma
    Jaime Landman
    Division of Urology, Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 167:2387-91. 2002
    ..Therefore, we compared standard and hand assisted laparoscopic radical nephroureterectomy for localized upper tract transitional cell carcinoma...
  32. pmc Magnetic resonance diffusion characteristics of histologically defined prostate cancer in humans
    Junqian Xu
    Department of Chemistry, Washington University, St Louis, Missouri 63110, USA
    Magn Reson Med 61:842-50. 2009
    ..PCa identified in volume rendered MR images qualitatively correlates well with histologically determined PCa foci...
  33. ncbi request reprint Management of the postpubertal patient with cryptorchidism: an updated analysis
    Joseph Oh
    Division of Urology, Department of Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA
    J Urol 167:1329-33. 2002
    ..We revisited the topic using contemporary data to determine whether and how recommendations on management of the postpubertal cryptorchid testis should be changed...
  34. pmc SnoRNA U50 is a candidate tumor-suppressor gene at 6q14.3 with a mutation associated with clinically significant prostate cancer
    Xue Yuan Dong
    Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Road, Atlanta, GA 30322, USA
    Hum Mol Genet 17:1031-42. 2008
    ..9; 95% confidence interval 1.17-7.21). These findings establish snoRNA U50 as a reasonable candidate for the 6q tumor-suppressor gene in prostate cancer and likely in other types of cancers...
  35. ncbi request reprint Optimizing prostate biopsy techniques
    Adam S Kibel
    J Urol 177:1976-7. 2007
  36. ncbi request reprint The use and abuse of data: nomograms and talking to patients about clinical medicine
    Seth P Lerner
    Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, USA
    Urol Oncol 25:333-7. 2007
    ..To review the development of nomograms and consortia efforts applying these tools to model outcome predictions associated with radical cystectomy...
  37. ncbi request reprint The Second Joint Meeting of American Urological Association (AUA)/Japanese Urological Association (JUA) International Program on the 102nd Annual Meeting of American Urological Association at Anaheim 2007
    Kenneth Ogan
    Emory University, USA
    Int J Urol 14:1116-23. 2007

Research Grants6

  1. Genetic Risk Profiling in Metastatic Prostate Carcinoma
    Adam Kibel; Fiscal Year: 2004
    ..At the conclusion of this study, we will have a panel of markers with the potential to predict, in future prospective studies, which patients are at high risk of eventual death from prostate carcinoma. ..
  2. IDENTIFICATION OF A 12P PROSTATE TUMOR SUPPRESSOR GENE
    Adam Kibel; Fiscal Year: 2006
    ..The identification of a novel tumor suppressor would provide a target for better prostate cancer therapy and/or more accurate prognostic information for men newly diagnosed with the disease. ..
  3. Cell Cycle Variants and Metastatic Prostate Cancer Risk
    Adam Kibel; Fiscal Year: 2009
    ..At the conclusion of this study, we will have a panel of markers that can be used to predict which patients are at high risk of treatment failure and eventual death from prostate carcinoma. ..