Research Topics
| P W KalivasSummaryAffiliation: Washington State University Country: USA Publications
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Publications
Dopamine regulation of extracellular glutamate in the nucleus accumbensP W Kalivas
Department of Veterinary Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman 99164 6520, USA
Brain Res 761:173-7. 1997..Both SCH-23390 and sulpiride prevented the reduction in extracellular glutamate by amphetamine. The data indicate that, similar to the striatum, glutamate release in the nucleus accumbens is modulated by presynaptic dopamine receptors...
A role for sensitization in craving and relapse in cocaine addictionP W Kalivas
Alcohol and Drug Abuse Program, Washington State University, Pullman 99164 6520, USA
J Psychopharmacol 12:49-53. 1998..It is proposed that the pharmacological neuroadaptations predominate in the manifestation of cocaine-induced paranoia, while the changes derived from learning may provide more critical underpinnings for cocaine craving and relapse...
Autoradiographic localization of mu-opioid and neurotensin receptors within the mesolimbic dopamine systemR P Dilts
Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman 99164
Brain Res 488:311-27. 1989..These results are consistent with the pharmacological effects of mu-opioids and neurotensin, and suggest an indirect modulation of the mesolimbic dopamine neurons by mu-opioid agonists and the endogenous opioid peptides...
Changes in gamma-aminobutyric acid, mu-opioid and neurotensin receptors in the accumbens-pallidal projection after discrete quinolinic acid lesions in the nucleus accumbensL Churchill
Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, College of Veterinary Medicine, Washington State University, Pullman 99164
Brain Res 511:41-54. 1990..Fluoro-gold retrograde tracer histochemistry confirmed the specific projection from the dorsomedial core to the dorsal ventral pallidum; and from the shell of the nucleus accumbens to more ventral regions of the ventral pallidum...
The NMDA antagonist, dizocilpine, enhances cocaine reinforcement without influencing mesoaccumbens dopamine transmissionR C Pierce
Alcohol and Drug Abuse Program, Washington State University, Pullman 99164 6520, USA
Psychopharmacology (Berl) 133:188-95. 1997..Collectively, these findings suggest that dizocilpine enhances the reinforcing effect of cocaine without influencing dopamine transmission in the nucleus accumbens shell...
Autoradiographic localization of delta opioid receptors within the mesocorticolimbic dopamine system using radioiodinated [2-D-penicillamine, 5-D-penicillamine]enkephalin (125I-DPDPE)R P Dilts
Department of Veterinary Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman 99164 6520
Synapse 6:121-32. 1990..These results suggest that the enkephalins and opioid agonists acting through delta opioid receptors do not directly modulate dopaminergic afferents but do regulate postsynaptic targets of the mesocorticolimbic dopamine system...
A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulantsR C Pierce
Alcohol and Drug Abuse Program, Washington State University, Pullman 99164 6520, USA
Brain Res Brain Res Rev 25:192-216. 1997..This neural circuit is used as a template to organize the relevant biochemical and molecular findings into a model of the expression of behavioral sensitization...
Autoradiographic localization of gamma-aminobutyric acidA receptors within the ventral tegmental areaL Churchill
Department of Veterinary and Comparative Anatomy, Washington State University, Pullman 99164 6520
Neurochem Res 17:101-6. 1992..These results are consistent with the predominant localization of GABAA receptors to non-dopaminergic neurons intrinsic to the VTA...
