P A Humphrey

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. doi request reprint Histological variants of prostatic carcinoma and their significance
    Peter A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Histopathology 60:59-74. 2012
  2. pmc Diagnosis of adenocarcinoma in prostate needle biopsy tissue
    P A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Clin Pathol 60:35-42. 2007
  3. ncbi request reprint Gleason grading and prognostic factors in carcinoma of the prostate
    Peter A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Mod Pathol 17:292-306. 2004
  4. ncbi request reprint Prostate cancer diagnosis
    Peter A Humphrey
    Washington University School of Medicine in St Louis, USA
    Mo Med 107:107-12. 2010
  5. ncbi request reprint Urinary bladder pathology 2004: an update
    Peter A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Ann Diagn Pathol 8:380-9. 2004
  6. ncbi request reprint Prognostic significance of plasma scatter factor/hepatocyte growth factor levels in patients with metastatic hormone- refractory prostate cancer: results from cancer and leukemia group B 150005/9480
    Peter A Humphrey
    Washington University Medical Center, St Louis, MO 63110, USA
    Clin Genitourin Cancer 4:269-74. 2006
  7. ncbi request reprint Frequent and early loss of the EGR1 corepressor NAB2 in human prostate carcinoma
    S A Abdulkadir
    Department of Pathology and Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Hum Pathol 32:935-9. 2001
  8. pmc Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis
    H Song
    Department of Pathology and Immunology, School of Medicine, Washington University at St Louis, St Louis, MO 63110, USA
    Oncogene 28:3307-19. 2009
  9. ncbi request reprint Scatter factor-hepatocyte growth factor elevation in the serum of patients with prostate cancer
    M Naughton
    Division of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA
    J Urol 165:1325-8. 2001
  10. ncbi request reprint Multiple measures of carcinoma extent versus perineural invasion in prostate needle biopsy tissue in prediction of pathologic stage in a screening population
    Tarek A Bismar
    Lauren V Ackerman Laboratory of Surgical Pathology, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Am J Surg Pathol 27:432-40. 2003

Detail Information

Publications64

  1. doi request reprint Histological variants of prostatic carcinoma and their significance
    Peter A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Histopathology 60:59-74. 2012
    ....
  2. pmc Diagnosis of adenocarcinoma in prostate needle biopsy tissue
    P A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Clin Pathol 60:35-42. 2007
    ..Measures of tumour extent are (1) number of cores positive for cancer in the number of cores examined, (2) percentage of needle core tissue affected by carcinoma and (3) linear millimetres of carcinoma present...
  3. ncbi request reprint Gleason grading and prognostic factors in carcinoma of the prostate
    Peter A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Mod Pathol 17:292-306. 2004
    ..Currently, established prognostic factors for prostatic carcinoma recommended for routine reporting are TNM stage, surgical margin status, serum prostate-specific antigen, and Gleason grade...
  4. ncbi request reprint Prostate cancer diagnosis
    Peter A Humphrey
    Washington University School of Medicine in St Louis, USA
    Mo Med 107:107-12. 2010
    ..This article reviews clinical and pathological approaches to prostate cancer diagnosis, with a focus on clinically localized disease and needle biopsy diagnosis...
  5. ncbi request reprint Urinary bladder pathology 2004: an update
    Peter A Humphrey
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Ann Diagn Pathol 8:380-9. 2004
    ..The aim of this presentation is to survey selected, recent advances in this broad field, with specific focus on histologic typing, grading, staging, molecular classification, and reporting on neoplasia of the urinary bladder...
  6. ncbi request reprint Prognostic significance of plasma scatter factor/hepatocyte growth factor levels in patients with metastatic hormone- refractory prostate cancer: results from cancer and leukemia group B 150005/9480
    Peter A Humphrey
    Washington University Medical Center, St Louis, MO 63110, USA
    Clin Genitourin Cancer 4:269-74. 2006
    ..Scatter factor, also known as hepatocyte growth factor (SF/HGF), is a polypeptide growth factor thought to be important in the growth and spread of prostatic carcinoma...
  7. ncbi request reprint Frequent and early loss of the EGR1 corepressor NAB2 in human prostate carcinoma
    S A Abdulkadir
    Department of Pathology and Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Hum Pathol 32:935-9. 2001
    ..Our findings suggest that high levels of EGR1 coupled with low levels of NAB2 can result in high, unrestrained EGR1 transcriptional activity in human prostate cancers...
  8. pmc Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis
    H Song
    Department of Pathology and Immunology, School of Medicine, Washington University at St Louis, St Louis, MO 63110, USA
    Oncogene 28:3307-19. 2009
    ..1 loss depend on the epithelial proliferative stage at which its expression is lost, and that alterations in the PTEN-AKT-NKX3.1 axis are important for prostate cancer initiation...
  9. ncbi request reprint Scatter factor-hepatocyte growth factor elevation in the serum of patients with prostate cancer
    M Naughton
    Division of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA
    J Urol 165:1325-8. 2001
    ..SF-HGF levels are associated with metastatic prostate cancer independent of the prostate specific antigen level and patient age. These data imply that SF-HGF may be an important serum marker for prostate cancer...
  10. ncbi request reprint Multiple measures of carcinoma extent versus perineural invasion in prostate needle biopsy tissue in prediction of pathologic stage in a screening population
    Tarek A Bismar
    Lauren V Ackerman Laboratory of Surgical Pathology, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Am J Surg Pathol 27:432-40. 2003
    ..Reporting of several measures of carcinoma extent in needle biopsy tissue is recommended...
  11. ncbi request reprint Relating biopsy and clinical variables to radical prostatectomy findings: can insignificant and advanced prostate cancer be predicted in a screening population?
    Jason W Anast
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 64:544-50. 2004
    ....
  12. doi request reprint Microcystic adenocarcinoma of the prostate: a variant of pseudohyperplastic and atrophic patterns
    Oksana Yaskiv
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Surg Pathol 34:556-61. 2010
    ..Diagnostic awareness of this growth pattern of prostatic carcinoma is important to avoid underdiagnosis of adenocarcinoma of the prostate...
  13. ncbi request reprint Prostate-specific antigen cutoff of 2.6 ng/mL for prostate cancer screening is associated with favorable pathologic tumor features
    Jason S Krumholtz
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 60:469-73; discussion 473-4. 2002
    ..6 to 4.0-ng/mL PSA range and compare them with Stage T1c cancers concurrently detected in the 4.1 to 10.0-ng/mL PSA range. All cancers were detected in a prostate cancer screening study...
  14. ncbi request reprint Stratified epithelium in prostatic adenocarcinoma: a mimic of high-grade prostatic intraepithelial neoplasia
    Omar Hameed
    Department of Pathology and Immunology, Washington University Medical Center, St Louis, MO 63110, USA
    Mod Pathol 19:899-906. 2006
    ..These 'PIN-like' carcinomas can present in pure form. Recognition of this pattern of prostatic adenocarcinoma is necessary to correctly diagnose such cases as invasive carcinoma...
  15. ncbi request reprint Expression profiling reveals hepsin overexpression in prostate cancer
    J A Magee
    Department of Pathology, Division of Laboratory Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, Missouri 63110, USA
    Cancer Res 61:5692-6. 2001
    ..These facts, together with the molecular properties of hepsin, make it an ideal target for prostate cancer therapy...
  16. doi request reprint Prospective study of [18F]fluorodeoxyglucose positron emission tomography/computed tomography for staging of muscle-invasive bladder carcinoma
    Adam S Kibel
    Division of Urologic Surgery, Washington University School of Medicine, 4960 Children s Place, Box 8242, St Louis, MO 63105, USA
    J Clin Oncol 27:4314-20. 2009
    ..Herein, we report a prospective study of positron emission tomography/computed tomography (PET/CT) with [(18)F]fluorodeoxyglucose (FDG) in patients undergoing radical cystectomy for cT2-3N0M0 urothelial carcinoma of the bladder...
  17. doi request reprint SALL4 is a novel diagnostic marker for testicular germ cell tumors
    Dengfeng Cao
    The Lauren V Ackerman Laboratory of Surgical Pathology, Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University in Saint Louis, 660 S Euclid Avenue, Campus Box 8118, Saint Louis, MO 63110, USA
    Am J Surg Pathol 33:1065-77. 2009
    ..Our findings indicate that SALL4 is a novel sensitive and relatively specific marker for testicular GCTs. SALL4 is a more sensitive marker than AFP and glypican-3 for YST...
  18. doi request reprint SALL4 is a novel sensitive and specific marker for metastatic germ cell tumors, with particular utility in detection of metastatic yolk sac tumors
    Dengfeng Cao
    The Lauren V Ackerman Laboratory of Surgical Pathology, Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer 115:2640-51. 2009
    ..In the current study, the authors investigated the utility of SALL4 as a potential diagnostic marker for metastatic germ cell tumors...
  19. ncbi request reprint Immunohistochemistry in diagnostic surgical pathology of the prostate
    Omar Hameed
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, Missouri 63110, USA
    Semin Diagn Pathol 22:88-104. 2005
    ....
  20. doi request reprint Is there a better way to biopsy the prostate? Prospects for a novel transrectal systematic biopsy approach
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 70:22-6. 2007
    ..Its reproducibility from operator to operator suggests that it may be useful for guiding rebiopsy of specific locations within the prostate and for providing targeted focal prostate cancer therapy...
  21. doi request reprint Effect of reclassification on the incidence of benign and malignant renal tumors
    Ted A Skolarus
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine and Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    J Urol 183:455-8. 2010
    ..To further investigate the impact of histological reclassification we reexamined all excised renal masses using the 2004 WHO criteria and compared this histological classification to the prior criteria...
  22. doi request reprint Open versus laparoscopic retroperitoneal lymph node dissection: assessing adequacy of dissection in a porcine model
    Brian M Benway
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Endourol 23:485-8. 2009
    ..We therefore sought to compare the completeness of dissection between O-RPLND and L-RPLND in a porcine model...
  23. doi request reprint Percent microscopic tumor necrosis and survival after curative surgery for renal cell carcinoma
    Matthew D Katz
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 183:909-14. 2010
    ..We determined whether a correlation exists between the amount (not just the presence/absence) of tumor necrosis, and metastasis-free, disease specific and overall survival after surgery for renal cell carcinoma...
  24. doi request reprint The Gleason score of tumor at the margin in radical prostatectomy is predictive of biochemical recurrence
    Dengfeng Cao
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Surg Pathol 34:994-1001. 2010
    ..Reporting the Gleason score of the tumor at the margin can improve predictive accuracy of biochemical recurrence. We advocate reporting the Gleason score of tumor at the margin in radical prostatectomy...
  25. doi request reprint Bile duct-like differentiation in teratoma: a clinicopathologic and immunohistochemical study
    Andres A Roma
    Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Ann Diagn Pathol 14:402-7. 2010
    ....
  26. ncbi request reprint Exaggerated signet-ring cell change in stromal nodule of prostate: a pseudoneoplastic proliferation
    Hanlin L Wang
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110 1093, U S A
    Am J Surg Pathol 26:1066-70. 2002
    ..This case demonstrates that signet-ring cell change may occur in benign, hyperplastic, prostatic stromal cells in the absence of cellular damage...
  27. ncbi request reprint Carcinoma extent in prostate needle biopsy tissue in the prediction of whole gland tumor volume in a screening population
    James S Lewis
    Lauren V Ackerman Laboratory of Surgical Pathology, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Clin Pathol 118:442-50. 2002
    ..Findings highlight the importance of reporting quantitative measures of tumor amount in prostate needle biopsy specimens; several measures of tumor extent (vs 1 measure) provide maximal information on prostate cancer size...
  28. ncbi request reprint Patterns of multiple recurrences of superficial (Ta/T1) transitional cell carcinoma of bladder and effects of clinicopathologic and biochemical factors
    Yan Yan
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer 95:1239-46. 2002
    ....
  29. ncbi request reprint Visceral primitive peripheral neuroectodermal tumors: a clinicopathologic and molecular study
    E J Perlman
    Lauren V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St Louis, MO 63110, USA
    Hum Pathol 32:1109-15. 2001
    ..05, chi(2) test). These results firmly establish the genetic relationship between EWS/PNET of visceral sites, soft tissue, and bone...
  30. ncbi request reprint Squamous cell carcinoma arising in recurrent respiratory papillomatosis with pulmonary involvement: emerging common pattern of clinical features and human papillomavirus serotype association
    J R Cook
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology, Washington University School of Medicine, St Louis, Missouri, USA
    Mod Pathol 13:914-8. 2000
    ....
  31. ncbi request reprint Value of CDX2, villin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma
    Namsoo Suh
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Mod Pathol 18:1217-22. 2005
    ..Lack of CDX2 and villin signals points strongly to a bladder primary...
  32. doi request reprint Percentage of high-grade carcinoma as a prognostic indicator in patients with renal cell carcinoma
    Maria F Serrano
    Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer 113:477-83. 2008
    ..However, to the authors' knowledge, the prognostic significance of the amount of high-grade renal cell carcinoma has not been previously analyzed...
  33. pmc Impact of comorbidity on overall survival in patients surgically treated for renal cell carcinoma
    David A Berger
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63105, USA
    Urology 72:359-63. 2008
    ..Because patients with renal cell carcinoma often have other medical conditions, we explored the effect of preexisting medical disease on survival after radical and partial nephrectomy...
  34. doi request reprint Gene expression profiles of ductal versus acinar adenocarcinoma of the prostate
    Souzan Sanati
    Department of Pathology and Immunology, Division of Anatomic and Molecular Pathology, Washington University School of Medicine, University Medical Center, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Mod Pathol 22:1273-9. 2009
    ....
  35. ncbi request reprint Immunohistochemical stains for p63 and alpha-methylacyl-CoA racemase, versus a cocktail comprising both, in the diagnosis of prostatic carcinoma: a comparison of the immunohistochemical staining of 430 foci in radical prostatectomy and needle biopsy tissu
    Omar Hameed
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, MO 63110, USA
    Am J Surg Pathol 29:579-87. 2005
    ..This cocktail would be of diagnostic utility when only limited tissue is available for immunohistochemical evaluation of small, diagnostically difficult foci in prostate needle biopsy tissue...
  36. pmc A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells
    E M Garabedian
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 95:15382-7. 1998
    ..This model indicates that the neuroendocrine cell lineage of the prostate is exquisitely sensitive to transformation and provides insights about the significance of neuroendocrine differentiation in human prostate cancer...
  37. pmc Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinoma
    P A Humphrey
    Department of Pathology, Washington University Medical Center, St Louis, Missouri 63110, USA
    Am J Pathol 147:386-96. 1995
    ....
  38. ncbi request reprint Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice
    Yan Hu
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 277:44462-74. 2002
    ..These results underscore the value of CR2-TAg mice for characterizing normal NE cell biology and tumorigenesis...
  39. ncbi request reprint Basal cell hyperplasia in the peripheral zone of the prostate
    Phataraporn Thorson
    Lauren V Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St Louis, Missouri 63110, USA
    Mod Pathol 16:598-606. 2003
    ....
  40. ncbi request reprint Expression of beta-catenin in prostatic adenocarcinomas: a comparison with colorectal adenocarcinomas
    Tark A Bismar
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Am J Clin Pathol 121:557-63. 2004
    ..The immunophenotypes documented herein also might aid in the distinction between prostatic and colorectal origins when metastasis is encountered...
  41. ncbi request reprint Impaired prostate tumorigenesis in Egr1-deficient mice
    S A Abdulkadir
    Department of Pathology, Washington University, Box 8118, 660 S Euclid Avenue, St Louis, Missouri 63119, USA
    Nat Med 7:101-7. 2001
    ..These results indicate a unique role for Egr1 in regulating the transition from localized, carcinoma in situ to invasive carcinoma...
  42. ncbi request reprint Renal hypothermia achieved by retrograde intracavitary saline perfusion
    Jaime Landman
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    J Endourol 16:445-9. 2002
    ..We evaluated the utility of a newly developed ureteral access system for circulating ice-cold saline...
  43. ncbi request reprint Determination of cell viability after laparoscopic tissue stapling in a porcine model
    Ramakrishna Venkatesh
    Department of Surgery, Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    J Endourol 19:744-7. 2005
    ....
  44. ncbi request reprint p63/AMACR antibody cocktail restaining of prostate needle biopsy tissues after transfer to charged slides: a viable approach in the diagnosis of small atypical foci that are lost on block sectioning
    Omar Hameed
    Department of Pathology and Immunology, Lauren V Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St Louis, MO 63110, USA
    Am J Clin Pathol 124:708-15. 2005
    ..This approach is best used when 2 or more H&E-stained sections harbor the suspicious focus, as we always recommended preservation of at least 1 H&E-stained section...
  45. ncbi request reprint Enhanced renal parenchymal cryoablation with novel 17-gauge cryoprobes
    Caroline D Ames
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 64:173-5. 2004
    ..To evaluate novel, 17-gauge cryoprobes with a modified heat exchange mechanism to evaluate the area of ablation that could be achieved with 17-gauge (1.47-mm) cryoprobes...
  46. ncbi request reprint Laparoscopic mid sagittal hemicystectomy and bladder reconstruction with small intestinal submucosa and reimplantation of ureter into small intestinal submucosa: 1-year followup
    Jaime Landman
    Department of Pathology, Washington University School of Medicine, St Louis, Missouri
    J Urol 171:2450-5. 2004
    ..We evaluated the long-term results of laparoscopic hemicystectomy and bladder replacement with small intestinal submucosa (SIS) with ureteral reimplantation into the SIS material...
  47. ncbi request reprint The distribution of histological subtypes of renal tumors by decade of life using the 2004 WHO classification
    Ted A Skolarus
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine and Barnes Jewish Hospital, St Louis, Missouri, USA
    J Urol 179:439-43; discussion 443-4. 2008
    ..We reviewed all partial and radical nephrectomy specimens at Barnes-Jewish Hospital to determine if the distribution of renal tumor histological subtypes varies by decade of life using the new scheme...
  48. pmc Magnetic resonance diffusion characteristics of histologically defined prostate cancer in humans
    Junqian Xu
    Department of Chemistry, Washington University, St Louis, Missouri 63110, USA
    Magn Reson Med 61:842-50. 2009
    ..PCa identified in volume rendered MR images qualitatively correlates well with histologically determined PCa foci...
  49. ncbi request reprint Percent carcinoma in prostatectomy specimen is associated with risk of recurrence after radical prostatectomy in patients with pathologically organ confined prostate cancer
    Christian G Ramos
    Clinica Las Condes, Santiago, Chile
    J Urol 172:137-40. 2004
    ..We evaluated tumor size, measured as the percent of the prostate involved by cancer, as a predictor of tumor recurrence after radical prostatectomy in patients with pathologically organ confined prostate cancer...
  50. ncbi request reprint Updated protocol for the examination of specimens from patients with carcinoma of the urinary bladder, ureter, and renal pelvis
    Mahul B Amin
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Arch Pathol Lab Med 127:1263-79. 2003
  51. ncbi request reprint High-grade prostatic intraepithelial neoplasia in needle biopsy as risk factor for detection of adenocarcinoma: current level of risk in screening population
    Neriman Gokden
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Urology 65:538-42. 2005
    ....
  52. ncbi request reprint Tumor volume in prostate cancer and serum prostate-specific antigen. Analysis from a kinetic viewpoint
    Robin T Vollmer
    Veterans Affairs Medical Center, Department of Pathology, Duke University Medical Center, Durham, NC, USA
    Am J Clin Pathol 119:80-9. 2003
    ..Nevertheless, surrogates for the missing parameters may exist and could lead to statistical models that could improve the prediction of tumor volume...
  53. ncbi request reprint Outcome for repeated biopsy of the prostate: roles of serum PSA, small atypical glands, and prostatic intraepithelial neoplasia
    Fadi Brimo
    Department of Pathology, Montreal General Hospital, Montreal, Canada
    Am J Clin Pathol 128:648-51. 2007
    ..For higher PSA values, the presence of ASAPs dramatically increases the probability of a positive follow-up biopsy result compared with cases with no atypia or PIN in the first biopsy specimen...
  54. ncbi request reprint Urothelial neoplasms in patients 20 years or younger: a clinicopathological analysis using the world health organization 2004 bladder consensus classification
    Samson W Fine
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Urol 174:1976-80. 2005
    ..Urothelial neoplasms in patients younger than 20 years are rare, with conflicting data regarding clinical outcomes...
  55. ncbi request reprint High-grade prostate cancer in the Prostate Cancer Prevention Trial: fact or artifact?
    Gerald L Andriole
    J Natl Cancer Inst 99:1355-6. 2007
  56. ncbi request reprint The morphologic spectrum of metastatic prostatic adenocarcinoma to the lung: special emphasis on histologic features overlapping with other pulmonary neoplasms
    John N Copeland
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Am J Clin Pathol 117:552-7. 2002
    ..Attention to specific discriminating histologic features, supported by immunohistochemical staining, may be useful in the differential diagnosis, which is therapeutically and prognostically critical...
  57. ncbi request reprint Updated protocol for the examination of specimens from patients with carcinomas of the prostate gland
    John R Srigley
    Department of Laboratory Medicine, Credit Valley Hospital, Mississauga, Ontario, Canada
    Arch Pathol Lab Med 130:936-46. 2006
  58. doi request reprint Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathology
    Mathieu Latour
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1532-9. 2008
    ..In conclusion, most of the small cribriform cancer foci seen on needle biopsy should be interpreted as Gleason pattern 4 and not pattern 3...
  59. ncbi request reprint Large cell neuroendocrine carcinoma of prostate: a clinicopathologic summary of 7 cases of a rare manifestation of advanced prostate cancer
    Andrew J Evans
    Department of Pathology and Laboratory Medicine, University Health Network, Mt Sinai Hospital, Toronto, Ontario, Canada
    Am J Surg Pathol 30:684-93. 2006
    ..LCNEC of prostate is a distinct clinicopathologic entity that typically manifests after long-term hormonal therapy for prostatic adenocarcinoma and likely arises through clonal progression under the selection pressure of therapy...
  60. doi request reprint Tissue response to surgical energy devices
    Courtney K Phillips
    Department of Urology, Columbia University Medical Center, New York, New York, USA
    Urology 71:744-8. 2008
    ..As such, we quantified the lateral thermal damage associated with contemporary ESD: the Harmonic ACE, a prototype bipolar device known as the Gyrus Trisector, the Harmonic LCS-C5, and the LigaSure V...
  61. ncbi request reprint Evaluation of surgical energy devices for vessel sealing and peripheral energy spread in a porcine model
    Gregory W Hruby
    Department of Urology, Columbia University Medical Center, New York, New York, USA
    J Urol 178:2689-93. 2007
    ..Vessel sealing capabilities and the peripheral energy spread associated with currently available energy based surgical instruments were evaluated...
  62. pmc Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia
    Sarki A Abdulkadir
    Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
    Mol Cell Biol 22:1495-503. 2002
    ..1 allele lose expression of the wild-type allele. Our results support the role of NKX3.1 as a prostate tumor suppressor and indicate a role for this gene in tumor initiation...
  63. ncbi request reprint Transcripts, transcripts, everywhere
    Maureen J O'Sullivan
    Adv Anat Pathol 9:265-6; author reply 266-7. 2002
  64. ncbi request reprint Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee
    Scott B Shappell
    Department of Pathology and Vanderbilt Prostate Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37210, USA
    Cancer Res 64:2270-305. 2004
    ....