Kathryn L Huisinga

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint The contradictory definitions of heterochromatin: transcription and silencing
    Kathryn L Huisinga
    Department of Biology, Washington University, Saint Louis, MO 63130, USA
    Chromosoma 115:110-22. 2006
  2. pmc A TATA binding protein regulatory network that governs transcription complex assembly
    Kathryn L Huisinga
    Center for Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Genome Biol 8:R46. 2007
  3. pmc Structural and functional analysis of mutations along the crystallographic dimer interface of the yeast TATA binding protein
    Haiping Kou
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16803, USA
    Mol Cell Biol 23:3186-201. 2003
  4. ncbi request reprint Interplay of TBP inhibitors in global transcriptional control
    Carmelata Chitikila
    Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16803, USA
    Mol Cell 10:871-82. 2002
  5. ncbi request reprint A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae
    Kathryn L Huisinga
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Mol Cell 13:573-85. 2004
  6. pmc Small RNA-directed heterochromatin formation in the context of development: what flies might learn from fission yeast
    Kathryn L Huisinga
    Department of Biology, Washington University, St Louis, MO 63130, USA
    Biochim Biophys Acta 1789:3-16. 2009

Collaborators

  • B Pugh
  • SARAH C ELGIN
  • Haiping Kou
  • Jordan D Irvin
  • Carmelata Chitikila
  • Madhusmita Mitra
  • Andrew D Basehoar

Detail Information

Publications6

  1. ncbi request reprint The contradictory definitions of heterochromatin: transcription and silencing
    Kathryn L Huisinga
    Department of Biology, Washington University, Saint Louis, MO 63130, USA
    Chromosoma 115:110-22. 2006
    ..We discuss the implications of these new findings for the current definition of heterochromatin...
  2. pmc A TATA binding protein regulatory network that governs transcription complex assembly
    Kathryn L Huisinga
    Center for Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Genome Biol 8:R46. 2007
    ..Here, we model and experimentally test a portion of the assembly process involving the regulation of the TATA binding protein (TBP) throughout the yeast genome...
  3. pmc Structural and functional analysis of mutations along the crystallographic dimer interface of the yeast TATA binding protein
    Haiping Kou
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16803, USA
    Mol Cell Biol 23:3186-201. 2003
    ..These phenotypes cannot be accounted for by defective interactions with other known TBP inhibitors and likely reflect defects in TBP dimerization...
  4. ncbi request reprint Interplay of TBP inhibitors in global transcriptional control
    Carmelata Chitikila
    Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16803, USA
    Mol Cell 10:871-82. 2002
    ..These findings reveal that transcriptional output is limited in part by a collaboration of different combinations of TBP inhibitory mechanisms...
  5. ncbi request reprint A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae
    Kathryn L Huisinga
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Mol Cell 13:573-85. 2004
    ..These two distinct modes of transcription regulation might reflect the need to balance inducible stress responses with the steady output of housekeeping genes...
  6. pmc Small RNA-directed heterochromatin formation in the context of development: what flies might learn from fission yeast
    Kathryn L Huisinga
    Department of Biology, Washington University, St Louis, MO 63130, USA
    Biochim Biophys Acta 1789:3-16. 2009
    ..pombe system as a model, we analyze the role of small RNA pathway components and associated small RNAs in regulating transposable elements and potentially directing heterochromatin formation at these elements in Drosophila melanogaster...