Lori R Holtz

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Identification of a novel picornavirus related to cosaviruses in a child with acute diarrhea
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO USA
    Virol J 5:159. 2008
  2. pmc Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Virol J 6:86. 2009
  3. pmc Human stool contains a previously unrecognized diversity of novel astroviruses
    Stacy R Finkbeiner
    Department of Molecular Microbiology and Pathology, Washington University School of Medicine, St Louis, MO, USA
    Virol J 6:161. 2009
  4. pmc Comparison of novel MLB-clade, VA-clade and classic human astroviruses highlights constrained evolution of the classic human astrovirus nonstructural genes
    Hongbing Jiang
    Washington University School of Medicine, Department of Molecular Microbiology, St Louis, MO, USA
    Virology 436:8-14. 2013
  5. pmc Astrovirus MLB1 is not associated with diarrhea in a cohort of Indian children
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 6:e28647. 2011
  6. ncbi request reprint Discovery of rosavirus 2, a novel variant of a rodent-associated picornavirus, in children from The Gambia
    Efrem S Lim
    Departments of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Virology 454:25-33. 2014
  7. pmc Astrovirus MLB2 viremia in febrile child
    Lori R Holtz
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Emerg Infect Dis 17:2050-2. 2011
  8. pmc Detection of novel sequences related to african Swine Fever virus in human serum and sewage
    Joy Loh
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Box 8118, St Louis, MO 63110, USA
    J Virol 83:13019-25. 2009
  9. pmc Detection of newly described astrovirus MLB1 in stool samples from children
    Stacy R Finkbeiner
    Molecular Microbiology and Microbial Pathogenesis Program, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Emerg Infect Dis 15:441-4. 2009
  10. pmc Seroepidemiology of astrovirus MLB1
    Lori R Holtz
    Washington University School of Medicine, St Louis, Missouri, USA
    Clin Vaccine Immunol 21:908-11. 2014

Collaborators

Detail Information

Publications12

  1. pmc Identification of a novel picornavirus related to cosaviruses in a child with acute diarrhea
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO USA
    Virol J 5:159. 2008
    ..Based on the analysis discussed here, we propose that this virus represents a new species in the Cosavirus genus, and it has tentatively been named Human Cosavirus E1 (HCoSV-E1)...
  2. pmc Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Virol J 6:86. 2009
    ..In an effort to identify novel viruses that may be causal agents of diarrhea, we used high throughput mass sequencing to analyze stool samples collected from patients with acute diarrhea...
  3. pmc Human stool contains a previously unrecognized diversity of novel astroviruses
    Stacy R Finkbeiner
    Department of Molecular Microbiology and Pathology, Washington University School of Medicine, St Louis, MO, USA
    Virol J 6:161. 2009
    ..Given that a significant fraction of diarrhea etiologies is currently unknown, it is plausible that these or other yet unrecognized astroviruses may be responsible for at least part of the undiagnosed cases...
  4. pmc Comparison of novel MLB-clade, VA-clade and classic human astroviruses highlights constrained evolution of the classic human astrovirus nonstructural genes
    Hongbing Jiang
    Washington University School of Medicine, Department of Molecular Microbiology, St Louis, MO, USA
    Virology 436:8-14. 2013
    ....
  5. pmc Astrovirus MLB1 is not associated with diarrhea in a cohort of Indian children
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 6:e28647. 2011
    ..Furthermore, MLB1 viral load did not differ significantly between the cases and controls. The role of MLB1 in human health still remains unknown and future studies are needed...
  6. ncbi request reprint Discovery of rosavirus 2, a novel variant of a rodent-associated picornavirus, in children from The Gambia
    Efrem S Lim
    Departments of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Virology 454:25-33. 2014
    ..There was no statistical evidence that rosavirus 2 was associated with diarrheal cases. This study broadens our understanding of unknown viruses present in children in developing country settings. ..
  7. pmc Astrovirus MLB2 viremia in febrile child
    Lori R Holtz
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Emerg Infect Dis 17:2050-2. 2011
    ..We detected MLB2 in the plasma of a febrile child, which suggests that MLB2 has broader tropism than expected and disease potential beyond the gastrointestinal tract...
  8. pmc Detection of novel sequences related to african Swine Fever virus in human serum and sewage
    Joy Loh
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Box 8118, St Louis, MO 63110, USA
    J Virol 83:13019-25. 2009
    ..Detection of these sequences suggests that greater genetic diversity may exist among asfarviruses than previously thought and raises the possibility that human infection by asfarviruses may occur...
  9. pmc Detection of newly described astrovirus MLB1 in stool samples from children
    Stacy R Finkbeiner
    Molecular Microbiology and Microbial Pathogenesis Program, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Emerg Infect Dis 15:441-4. 2009
    ..Louis, Missouri, USA, was defined by reverse transcription-PCR. Of 254 stool specimens collected in 2008, 4 were positive for astrovirus MLB1. These results show that astrovirus MLB1 is circulating in North America...
  10. pmc Seroepidemiology of astrovirus MLB1
    Lori R Holtz
    Washington University School of Medicine, St Louis, Missouri, USA
    Clin Vaccine Immunol 21:908-11. 2014
    ..MLB1 seropositivity was high in children <6 months old, decreased to a nadir at 12 to 23 months old, and increased to 100% by adulthood. MLB1 infection is common, and primary exposure occurs in childhood. ..
  11. pmc Human polyomaviruses in children undergoing transplantation, United States, 2008-2010
    Erica A Siebrasse
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Emerg Infect Dis 18:1676-9. 2012
    ..All were detected; several were present in previously unreported specimen types...
  12. doi request reprint Acute bloody diarrhea: a medical emergency for patients of all ages
    Lori R Holtz
    Department of Pediatrics, Division of Gastroenterology and Nutrition, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Gastroenterology 136:1887-98. 2009
    ..These topics are discussed in the context of the medical care that is available to children and adults with bloody diarrhea in most institutions in developed nations...