David A Hess

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
    David A Hess
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Program, Washington University School of Medicine, 660 S Euclid Ave, Box 8007, St Louis, MO 63110, USA
    Blood 104:1648-55. 2004
  2. ncbi Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
    David A Hess
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Group, Washington University School of Medicine, Southwest Tower, Rm 644, 4940 Parkview Pl, Campus Box 8007, St Louis, MO 63110, USA
    Blood 107:2162-9. 2006
  3. ncbi Fluorophore-conjugated iron oxide nanoparticle labeling and analysis of engrafting human hematopoietic stem cells
    Dustin J Maxwell
    Molecular Imaging Center, Mallinckrodt Institute of Radiology, Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri, USA
    Stem Cells 26:517-24. 2008
  4. ncbi Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity
    David A Hess
    Hematopoietic Development and Malignancy Group, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Stem Cells 26:611-20. 2008
  5. ncbi Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor
    David A Hess
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Group, Washington University School of Medicine, 4940 Parkview Place, St Louis, MO 63110, USA
    Biol Blood Marrow Transplant 13:398-411. 2007
  6. ncbi Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity
    Benjamin J Capoccia
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Blood 113:5340-51. 2009
  7. ncbi Recent advances in hematopoietic stem cell biology
    Jesper Bonde
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Program, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    Curr Opin Hematol 11:392-8. 2004
  8. ncbi Immune-deficient mouse models for analysis of human stem cells
    Todd E Meyerrose
    Washington University School of Medicine, St. Louis, MO, USA
    Biotechniques 35:1262-72. 2003
  9. ncbi Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor
    David A Hess
    Developmental Stem Cell Biology and Regenerative Medicine, John P. Robarts Research Institute, London, Ontario, Canada
    Blood 100:869-78. 2002

Collaborators

Detail Information

Publications9

  1. ncbi Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
    David A Hess
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Program, Washington University School of Medicine, 660 S Euclid Ave, Box 8007, St Louis, MO 63110, USA
    Blood 104:1648-55. 2004
    ..Cell fractionation according to lineage depletion and ALDH activity provides a viable and prospective purification of HSCs on the basis of cell function rather than cell surface phenotype...
  2. ncbi Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
    David A Hess
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Group, Washington University School of Medicine, Southwest Tower, Rm 644, 4940 Parkview Pl, Campus Box 8007, St Louis, MO 63110, USA
    Blood 107:2162-9. 2006
    ..Cell selection based on ALDH activity and CD133 expression provides a novel purification of HSCs with long-term repopulating function and may be considered an alternative to CD34 cell selection for stem cell therapies...
  3. ncbi Fluorophore-conjugated iron oxide nanoparticle labeling and analysis of engrafting human hematopoietic stem cells
    Dustin J Maxwell
    Molecular Imaging Center, Mallinckrodt Institute of Radiology, Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri, USA
    Stem Cells 26:517-24. 2008
    ..The use of fluorophore-labeled iron oxide nanoparticles for fluorescence imaging in combination with flow cytometry allows evaluation of labeling efficiencies and homing capabilities of defined human HSC subsets...
  4. ncbi Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity
    David A Hess
    Hematopoietic Development and Malignancy Group, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Stem Cells 26:611-20. 2008
    ..ALDH-expressing progenitor cells demonstrated widespread and tissue-specific distribution of variable cellular phenotypes, indicating that these adult progenitor cells should be explored in transplantation models of tissue damage...
  5. ncbi Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor
    David A Hess
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Group, Washington University School of Medicine, 4940 Parkview Place, St Louis, MO 63110, USA
    Biol Blood Marrow Transplant 13:398-411. 2007
    ..Thus, AMD3100 mobilized peripheral blood represents a rapidly obtained, highly repopulating source of hematopoietic progenitors for clinical transplantation...
  6. ncbi Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity
    Benjamin J Capoccia
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Blood 113:5340-51. 2009
    ..These clinically relevant cells may prove useful in the treatment of critical ischemia in humans...
  7. ncbi Recent advances in hematopoietic stem cell biology
    Jesper Bonde
    Department of Internal Medicine, Division of Oncology, Hematopoietic Development and Malignancy Program, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    Curr Opin Hematol 11:392-8. 2004
    ..These discoveries will significantly advance the field of stem cell transplantation...
  8. ncbi Immune-deficient mouse models for analysis of human stem cells
    Todd E Meyerrose
    Washington University School of Medicine, St. Louis, MO, USA
    Biotechniques 35:1262-72. 2003
    ....
  9. ncbi Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor
    David A Hess
    Developmental Stem Cell Biology and Regenerative Medicine, John P. Robarts Research Institute, London, Ontario, Canada
    Blood 100:869-78. 2002
    ....