Andrew Heath

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Statistical methods in genetic research on smoking
    A C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Stat Methods Med Res 7:165-86. 1998
  2. ncbi request reprint Zygosity diagnosis in the absence of genotypic data: an approach using latent class analysis
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Twin Res 6:22-6. 2003
  3. ncbi request reprint Accuracy of mothers' retrospective reports of smoking during pregnancy: comparison with twin sister informant ratings
    Andrew C Heath
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Twin Res 6:297-301. 2003
  4. ncbi request reprint Ascertainment of a mid-western US female adolescent twin cohort for alcohol studies: assessment of sample representativeness using birth record data
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, USA
    Twin Res 5:107-12. 2002
  5. ncbi request reprint Gene-environment interaction effects on behavioral variation and risk of complex disorders: the example of alcoholism and other psychiatric disorders
    Andrew C Heath
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis 63108, USA
    Twin Res 5:30-7. 2002
  6. ncbi request reprint Towards a molecular epidemiology of alcohol dependence: analysing the interplay of genetic and environmental risk factors
    A C Heath
    Missouri Alcoholism Research Center, Washington University, St Louis, Missouri, USA
    Br J Psychiatry Suppl 40:s33-40. 2001
  7. ncbi request reprint A note on issues in meta-analysis for behavioral genetic studies using categorical phenotypes
    T A Ridenour
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Behav Genet 29:155-62. 1999
  8. ncbi request reprint Resiliency factors protecting against teenage alcohol use and smoking: influences of religion, religious involvement and values, and ethnicity in the Missouri Adolescent Female Twin Study
    A C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Twin Res 2:145-55. 1999
  9. pmc Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways
    Oscar Harari
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 7:e50913. 2012
  10. pmc Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers
    Sarah M Hartz
    Washington University School of Medicine, St Louis, Missouri, USA
    Arch Gen Psychiatry 69:854-60. 2012

Detail Information

Publications68

  1. ncbi request reprint Statistical methods in genetic research on smoking
    A C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Stat Methods Med Res 7:165-86. 1998
    ....
  2. ncbi request reprint Zygosity diagnosis in the absence of genotypic data: an approach using latent class analysis
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Twin Res 6:22-6. 2003
    ..In the absence of genotypic data, or as a safeguard against sample duplication, application of LCA for zygosity assignment or confirmation is strongly recommended...
  3. ncbi request reprint Accuracy of mothers' retrospective reports of smoking during pregnancy: comparison with twin sister informant ratings
    Andrew C Heath
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Twin Res 6:297-301. 2003
    ..We conclude that retrospective smoking data can safely be used to identify potential associations of later child outcomes with maternal smoking during pregnancy...
  4. ncbi request reprint Ascertainment of a mid-western US female adolescent twin cohort for alcohol studies: assessment of sample representativeness using birth record data
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, USA
    Twin Res 5:107-12. 2002
    ..Sampling biases were however small. The unusual cooperativeness in research of families with twins persists...
  5. ncbi request reprint Gene-environment interaction effects on behavioral variation and risk of complex disorders: the example of alcoholism and other psychiatric disorders
    Andrew C Heath
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis 63108, USA
    Twin Res 5:30-7. 2002
    ..Since few separated twin pairs will be available for study in the future, we also consider methods for modifying variance components linkage analysis to allow for environmental interactions with linked loci...
  6. ncbi request reprint Towards a molecular epidemiology of alcohol dependence: analysing the interplay of genetic and environmental risk factors
    A C Heath
    Missouri Alcoholism Research Center, Washington University, St Louis, Missouri, USA
    Br J Psychiatry Suppl 40:s33-40. 2001
    ..Progress in identifying genetic factors protective against alcohol dependence (AlcD) requires a paradigm shift in psychiatric epidemiology...
  7. ncbi request reprint A note on issues in meta-analysis for behavioral genetic studies using categorical phenotypes
    T A Ridenour
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Behav Genet 29:155-62. 1999
    ..These complexities emphasize the importance of being sensitive to the effects of misspecifying ascertainment corrections in any meta-analysis of behavioral genetic data...
  8. ncbi request reprint Resiliency factors protecting against teenage alcohol use and smoking: influences of religion, religious involvement and values, and ethnicity in the Missouri Adolescent Female Twin Study
    A C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Twin Res 2:145-55. 1999
    ..We speculate about the possible association between high heritability of African American religious behavior and an accelerated maturation of religious values during adolescence...
  9. pmc Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways
    Oscar Harari
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 7:e50913. 2012
    ....
  10. pmc Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers
    Sarah M Hartz
    Washington University School of Medicine, St Louis, Missouri, USA
    Arch Gen Psychiatry 69:854-60. 2012
    ..Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymous single-nucleotide polymorphism in CHRNA5, rs16969968...
  11. pmc Marital conflict and conduct problems in Children of Twins
    K Paige Harden
    Department of Psychology, University of Virginia, Charlottesville, VA 22902, USA
    Child Dev 78:1-18. 2007
    ..Furthermore, genetic influences mediated the association between marital conflict frequency and conduct problems. These results highlight the need for quasiexperimental designs in investigations of intergenerational associations...
  12. pmc Childhood sexual abuse and the course of alcohol dependence development: findings from a female twin sample
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Drug Alcohol Depend 89:139-44. 2007
    ..Findings indicate that CSA and elevated risk for AD may be linked via early age at first drink and that progression from first drink to AD follows a similar course among women with and without histories of CSA...
  13. ncbi request reprint A latent class analysis of illicit drug abuse/dependence: results from the National Epidemiological Survey on Alcohol and Related Conditions
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 102:94-104. 2007
    ..We examine the co-occurrence of abuse/dependence across different illicit drugs and test associations between these classes and major psychiatric disorders...
  14. ncbi request reprint Spousal concordance for alcohol dependence: evidence for assortative mating or spousal interaction effects?
    Julia D Grant
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 31:717-28. 2007
    ..The primary goal of the present analyses is to test hypotheses about the source(s) and magnitude of spousal associations for AD using a twin-spouse design...
  15. ncbi request reprint Genetic and environmental influences on emotion-modulated startle reflex: a twin study
    Andrey P Anokhin
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Psychophysiology 44:106-12. 2007
    ..Thus, our data do not support the hypothesis that emotion-modulated startle can serve as an indicator of genetically transmitted individual differences in affective processing...
  16. pmc The Nicotine Dependence Syndrome Scale in Finnish smokers
    Ulla Broms
    Department of Public Health, University of Helsinki, Mannerheimintie 172, P O Box 41, 00014 Helsinki, Finland
    Drug Alcohol Depend 89:42-51. 2007
    ..These analyses indicate that the NDSS functions well in a Finnish family-based sample and provide additional validation of a new scale developed to capture complex behavioural features of nicotine dependence...
  17. pmc Cohort trends in prevalence and spousal concordance for smoking
    Po Hsiu Kuo
    Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23219, USA
    Drug Alcohol Depend 88:122-9. 2007
    ..19-0.49). Despite using a simplified smoking assessment, findings in this study demonstrated changes of lifetime smoking patterns across birth cohorts and the presence of assortative mating for smoking behavior...
  18. ncbi request reprint Evidence for specificity of transmission of alcohol and nicotine dependence in an offspring of twins design
    Heather E Volk
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 87:225-32. 2007
    ..Despite the substantial genetic overlap between the two disorders, there is evidence for genetic effects specific for AD and ND...
  19. ncbi request reprint Genetic and environmental influences on extreme personality dispositions in adolescent female twins
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Child Psychol Psychiatry 47:902-9. 2006
    ....
  20. ncbi request reprint Exposure to paternal alcoholism does not predict development of alcohol-use disorders in offspring: evidence from an offspring-of-twins study
    Alexis E Duncan
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Avenue, Suite 1000, St Louis, Missouri 63110, USA
    J Stud Alcohol 67:649-56. 2006
    ..Cox proportional hazards models were fit to predict time to first symptom of abuse/dependence in offspring...
  21. ncbi request reprint Mental representations of attachment in identical female twins with and without conduct problems
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Ave, Campus Box 8134, St Louis, MO 63110, USA
    Child Psychiatry Hum Dev 37:65-72. 2006
    ..In this sample of twins with and without histories of Conduct Disorder, mental representations of attachment appear to be highly familial, i.e., strongly influenced by either shared environmental factors, genetic factors, or both...
  22. pmc A genetically informed study of the processes underlying the association between parental marital instability and offspring adjustment
    Brian M D'Onofrio
    Department of Psychology, University of Virginia, VA 47405, USA
    Dev Psychol 42:486-99. 2006
    ..In contrast, the increased risk for cohabitation and earlier initiation of drug use was explained by selection factors, including genetic confounds. ((c) 2006 APA, all rights reserved)...
  23. ncbi request reprint Clustering of eating disorder symptoms in a general population female twin sample: a latent class analysis
    Alexis E Duncan
    Department of Psychiatry and Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychol Med 37:1097-107. 2007
    ..The objective of the current study was to examine the clustering of ED symptoms in a general population sample using latent class analysis (LCA)...
  24. pmc Correlates of cannabis initiation in a longitudinal sample of young women: the importance of peer influences
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Prev Med 45:31-4. 2007
    ..In adolescent girls especially, rates of cannabis use have increased over the last decade, urging the need to characterize the potential correlates of onset of cannabis use during emerging adulthood...
  25. ncbi request reprint Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: genes or environment?
    Katherine I Morley
    Genetic Epidemiology Group, Queensland Institute of Medical Research, Queensland, Australia
    Psychol Med 37:1357-67. 2007
    ..We investigated the genetic and environmental contributions to covariation between smoking age-at-onset, cigarette consumption and smoking persistence...
  26. pmc Searching for an environmental effect of parental alcoholism on offspring alcohol use disorder: a genetically informed study of children of alcoholics
    Wendy S Slutske
    Department of Psychological Sciences, Midwest Alcoholism Research Center, University of Missouri Columbia, Columbia, MO 65211, USA
    J Abnorm Psychol 117:534-51. 2008
    ..The results of this study suggest that the direct causal effect of being exposed to an alcoholic parent on offspring alcohol use disorder is modest at best...
  27. doi request reprint Long-term stability and heritability of telephone interview measures of alcohol consumption and dependence
    Narelle K Hansell
    Genetic Epidemiology Unit, Queensland Institute of Medical Research, Post Office Royal Brisbane Hospital, Queensland, 4029, Australia
    Twin Res Hum Genet 11:287-305. 2008
    ..42 to .51 for dependence and from .31 to .51 for consumption. Consumption was significantly less heritable in the younger Phase 2 cohort (23-39 years) compared to the older Phase 1 cohort (28-90 years)...
  28. doi request reprint Effects of GABRA2 variation on physiological, psychomotor and subjective responses in the alcohol challenge twin study
    Penelope A Lind
    Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia
    Twin Res Hum Genet 11:174-82. 2008
    ..Because of the large number of phenotypes tested, these possibly significant findings will need to be confirmed in further studies...
  29. pmc Transitions to regular smoking and to nicotine dependence in women using cannabis
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 95:107-14. 2008
    ..If there is evidence in its favor, the increased rates of cigarette smoking in cannabis users may prove to be the most significant public health problem associated with cannabis use...
  30. doi request reprint Drinking expectancies and motives: a genetic study of young adult women
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Addiction 103:194-204. 2008
    ..However, little is known of the extent to which genetic and environmental influences contribute to individual differences in expectancies and motives...
  31. pmc Childhood sexual abuse moderates genetic influences on age at first consensual sexual intercourse in women
    Mary Waldron
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Campus Box 8134, St Louis, MO 63110, USA
    Behav Genet 38:1-10. 2008
    ..For both female and male twins, results from models that included conduct disorder as a covariate were near identical to results from models without conduct disorder...
  32. ncbi request reprint Early-onset alcohol-use behaviors and subsequent alcohol-related driving risks in young women: a twin study
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Road, Suite 1000, Saint Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 68:798-804. 2007
    ..The purpose of this study was to estimate associations between early-onset alcohol use/intoxication and subsequent risks of alcohol-related driving risks in young women after control for familial liability for these behaviors...
  33. pmc Evidence of genetic effects on blood lead concentration
    John B Whitfield
    Department of Clinical Biochemistry, Royal Prince Alfred Hospital, Sydney, Australia
    Environ Health Perspect 115:1224-30. 2007
    ..However, there has been little investigation of individual differences in lead absorption, distribution, or toxicity, or of genetic causes of such variation...
  34. pmc Differential etiology of posttraumatic stress disorder with conduct disorder and major depression in male veterans
    Qiang Fu
    Department of Community Health, Saint Louis University School of Public Health, St Louis, Missouri 63104, USA
    Biol Psychiatry 62:1088-94. 2007
    ..Epidemiologic studies reveal that posttraumatic stress disorder (PTSD) is highly comorbid with both conduct disorder and major depression in men. The genetic and environmental etiology of this comorbidity has not been examined...
  35. pmc Intergenerational transmission of childhood conduct problems: a Children of Twins Study
    Brian M D'Onofrio
    Department of Psychological and Brain Sciences, Indiana University, 1101 E 10th St, Bloomington, IN 47405, USA
    Arch Gen Psychiatry 64:820-9. 2007
    ..The familial nature of childhood conduct problems has been well documented, but few genetically informed studies have explicitly explored the processes through which parental conduct problems influence an offspring's behavior problems...
  36. pmc Common genetic risk of major depression and nicotine dependence: the contribution of antisocial traits in a United States veteran male twin cohort
    Qiang Fu
    Department of Community Health, St Louis University School of Public Health, St Louis, Missouri 63104, United States of America
    Twin Res Hum Genet 10:470-8. 2007
    ....
  37. ncbi request reprint Age at first sexual intercourse and teenage pregnancy in Australian female twins
    Mary Waldron
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, United States of America
    Twin Res Hum Genet 10:440-9. 2007
    ....
  38. ncbi request reprint Maternal alcohol use disorder and offspring ADHD: disentangling genetic and environmental effects using a children-of-twins design
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 36:1461-71. 2006
    ....
  39. ncbi request reprint Duration of cannabis use--a novel phenotype?
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Rd, Suite 1000, St Louis, MO 63110, United States
    Addict Behav 31:984-94. 2006
    ..While there were high genetic correlations in both women and men, lifetime duration of cannabis may be uniquely informative in assessing components of liability to cannabis use...
  40. ncbi request reprint Defining nicotine dependence for genetic research: evidence from Australian twins
    Christina N Lessov
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Psychol Med 34:865-79. 2004
    ....
  41. ncbi request reprint The genetics of alcohol intake and of alcohol dependence
    John B Whitfield
    Department of Clinical Biochemistry, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia
    Alcohol Clin Exp Res 28:1153-60. 2004
    ..The aims of this study were to assess the long-term repeatability and genetic or environmental causes of variation in alcohol intake and to estimate the degree of overlap with causes of susceptibility to alcohol dependence...
  42. ncbi request reprint Do the genetic or environmental determinants of anxiety and depression change with age? A longitudinal study of Australian twins
    Nathan A Gillespie
    Queensland Institute of Medical Research, Brisbane, Australia
    Twin Res 7:39-53. 2004
    ..These findings have significance for large scale depression prevention projects...
  43. ncbi request reprint Are substance use, abuse and dependence associated with study participation? Predictors of offspring nonparticipation in a twin-family study
    Jeffrey F Scherrer
    Research Service 151 JC, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, Missouri 63106, USA
    J Stud Alcohol 65:140-4. 2004
    ..In the current study we constructed a model of offspring nonparticipation in a twin-family design and computed weights to recapture the distribution of offspring alcohol abuse and dependence...
  44. ncbi request reprint Genetic epidemiology of alcohol-induced blackouts
    Elliot C Nelson
    Department of Psychiatry, Washington University School of Medicine and St Louis University School of Public Health, St Louis, O 63108, USA
    Arch Gen Psychiatry 61:257-63. 2004
    ..Alcohol-induced blackouts (ie, periods of anterograde amnesia) have received limited recent research attention...
  45. ncbi request reprint Reliability and stability of a semistructured DSM-IV interview designed for family studies
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Campus Box 8134, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 42:1460-8. 2003
    ....
  46. pmc Genetic epidemiology of self-reported lifetime DSM-IV major depressive disorder in a population-based twin sample of female adolescents
    Anne L Glowinski
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63108, USA
    J Child Psychol Psychiatry 44:988-96. 2003
    ..The goal of this study was the genetic analysis of MDD in an epidemiologically and genetically representative sample of adolescent female twins...
  47. ncbi request reprint Escalation of drug use in early-onset cannabis users vs co-twin controls
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    JAMA 289:427-33. 2003
    ..Previous studies have reported that early initiation of cannabis (marijuana) use is a significant risk factor for other drug use and drug-related problems...
  48. ncbi request reprint Genes, environment, and individual differences in alcohol expectancies among female adolescents and young adults
    Wendy S Slutske
    Missouri Alcoholism Research Center, Department of Psychological Sciences, University of Missouri Columbia, 65211, USA
    Psychol Addict Behav 16:308-17. 2002
    ..The extent to which the familial similarity for positive alcohol expectancies was moderated by age, race, drinking status, and the sharing of peer groups was also examined...
  49. ncbi request reprint Shared genetic risk of major depression, alcohol dependence, and marijuana dependence: contribution of antisocial personality disorder in men
    Qiang Fu
    Missouri Alcoholism Research Center at Washington University, Department of Psychiatry, Washington University School of Medicine, 40 N Kingshighway Blvd, Suite 2, St Louis, MO 63108, USA
    Arch Gen Psychiatry 59:1125-32. 2002
    ..We examined the contribution of genetic effects associated with ASPD to the comorbidity of MD and substance use disorders...
  50. ncbi request reprint Emotional and behavioral problems among female twins: an evaluation of the equal environments assumption
    Nikole J Cronk
    Missouri Alcoholism Research Center, Department of Psychological Sciences, University of Missouri Columbia, 65211, USA
    J Am Acad Child Adolesc Psychiatry 41:829-37. 2002
    ..To evaluate the equal environments assumption (EEA) of the twin method for mother-reported symptoms of child and adolescent emotional and behavioral problems...
  51. ncbi request reprint Discrimination of DSM-IV and latent class attention-deficit/hyperactivity disorder subtypes by educational and cognitive performance in a population-based sample of child and adolescent twins
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 41:820-8. 2002
    ..This report contrasts two ADHD subtyping approaches on the prediction of cognitive function and educational achievement...
  52. ncbi request reprint Estimating two-stage models for genetic influences on alcohol, tobacco or drug use initiation and dependence vulnerability in twin and family data
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Twin Res 5:113-24. 2002
    ..Illustrative application of the model to Australian twin data on smoking confirmed substantial heritability of smoking persistence (42%) with minimal overlap with genetic influences on initiation...
  53. ncbi request reprint Do college students drink more than their non-college-attending peers? Evidence from a population-based longitudinal female twin study
    Wendy S Slutske
    Department of Psychological Sciences, University of Missouri, 210 McAlester Hall, Columbia, MO 65211, USA
    J Abnorm Psychol 113:530-40. 2004
    ..These results are consistent with the conclusion that some aspect of the college experience may be an important environmental risk factor for this pattern of drinking among young adults...
  54. ncbi request reprint The genetics of middle-age spread in middle-class males
    James C Romeis
    Health Services Research, Department of Health Management and Policy, School of Public Health, Saint Louis University, St Louis, Missouri 63104, USA
    Twin Res 7:596-602. 2004
    ..The data analysis suggests that treatments and public health interventions need to recognize the magnitude of genetic factors if short-term and long-term interventions are to be effective...
  55. pmc Rapid discrimination of visual scene content in the human brain
    Andrey P Anokhin
    Department of Psychiatry, Washington University School of Medicine, 18 S Kingshighway, Suite 2T, St Louis, MO 63108, USA
    Brain Res 1093:167-77. 2006
    ....
  56. ncbi request reprint Genetic architecture of smoking behavior: a study of Finnish adult twins
    Ulla Broms
    Department of Public Health, University of Helsinki, Finland
    Twin Res Hum Genet 9:64-72. 2006
    ..This has implications for defining phenotypes in searches for genes underlying smoking behaviors...
  57. pmc Genetic influences on dynamic complexity of brain oscillations
    Andrey P Anokhin
    Washington University School of Medicine, Department of Psychiatry, 18 S Kingshighway, Suite 2T U, St Louis, MO 63108, USA
    Neurosci Lett 397:93-8. 2006
    ..Neurophysiological mechanisms mediating genetic variation in EEG complexity may include the degree of structural connectivity and functional differentiation among cortical neuronal assemblies...
  58. ncbi request reprint A possible smoking susceptibility locus on chromosome 11p12: evidence from sex-limitation linkage analyses in a sample of Australian twin families
    Katherine I Morley
    Genetic Epidemiology, Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, Queensland, Australia
    Behav Genet 36:87-99. 2006
    ..We identified one region suggestive of linkage on chromosome 11p12. This locus, as well as another region identified on chromosome 6p12, replicates regions identified in previous studies...
  59. ncbi request reprint Limitations of DSM-IV operationalizations of alcohol abuse and dependence in a sample of Australian twins
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Twin Res Hum Genet 8:574-84. 2005
    ....
  60. pmc A genetically informed study of marital instability and its association with offspring psychopathology
    Brian M D'Onofrio
    Department of Psychology, University of Virginia, Charlottesville, VA, USA
    J Abnorm Psychol 114:570-86. 2005
    ..The results are consistent with a causal connection between marital instability and psychopathology in young-adult offspring...
  61. ncbi request reprint Correlates of regular cigarette smoking in a population-based sample of Australian twins
    Arpana Agrawal
    Washington University School of Medicine, St Louis, MO 63108, USA
    Addiction 100:1709-19. 2005
    ..Design Members of monozygotic and dizygotic, including unlike-sex twin pairs (n = 6257) from a young adult cohort from the Australian Twin Registry...
  62. ncbi request reprint Heritability of SF-36 among middle-age, middle-class, male-male twins
    James C Romeis
    Comparative Aging and Health Status Laboratory, Department of Health Management and Policy, School of Public Health, Saint Louis University, St Louis, MO 63104 1314, USA
    Med Care 43:1147-54. 2005
    ....
  63. ncbi request reprint Evidence of age-dependent genetic influences on plasma total cholesterol
    Rita Middelberg
    Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia
    Eur J Cardiovasc Prev Rehabil 12:380-6. 2005
    ....
  64. ncbi request reprint Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 35:625-35. 2005
    ..Little attention, however, has been directed to investigating the roles of genetic transmission and prenatal exposure simultaneously...
  65. ncbi request reprint Paternal alcoholism and offspring conduct disorder: evidence for the 'common genes' hypothesis
    Jon R Haber
    Palo Alto Veterans Affairs Health Care System, Menlo Park, California, United States of America
    Twin Res Hum Genet 8:120-31. 2005
    ....
  66. ncbi request reprint The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression
    Nathan A Gillespie
    Queensland Institute of Medical Research, Royal Brisbane Hospital, Herston, Australia
    Psychol Med 35:101-11. 2005
    ....
  67. ncbi request reprint Genetic effects on alcohol dependence risk: re-evaluating the importance of psychiatric and other heritable risk factors
    Valerie S Knopik
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Psychol Med 34:1519-30. 2004
    ..Genetic influences have been shown to play a major role in determining the risk of alcohol dependence (AD) in both women and men; however, little attention has been directed to identifying the major sources of genetic variation in AD risk...
  68. ncbi request reprint Association between self-reported childhood sexual abuse and adverse psychosocial outcomes: results from a twin study
    Elliot C Nelson
    Washington University School of Medicine, Department of Psychiatry, 40 N Kingshighway, Suite 1, St Louis, MO 63108, USA
    Arch Gen Psychiatry 59:139-45. 2002
    ..Increased risk for serious adverse outcomes has been associated with a history of childhood sexual abuse (CSA). Whether these risks are directly attributable to CSA rather than family background remains controversial...

Research Grants31

  1. GxE in Early Childhood: Twin Mothers
    Andrew Heath; Fiscal Year: 2007
    ..In conjunction with R01s 2-4, these data will permit a powerful resolution of hypotheses concerning GE interplay effects on young children. ..
  2. Genetic Epideniologic Models of Alcohol Abuse
    Andrew Heath; Fiscal Year: 2007
    ..abstract_text> ..
  3. BIOMEDICAL TRAINING IN ALCOHOLISM RESEARCH
    Andrew Heath; Fiscal Year: 2007
    ....
  4. Parental Alcohlism & Child Environmental Risk
    Andrew Heath; Fiscal Year: 2007
    ..abstract_text> ..
  5. GxE in Early Childhood: Twin Mothers
    Andrew Heath; Fiscal Year: 2009
    ..In conjunction with R01s 2-4, these data will permit a powerful resolution of hypotheses concerning GE interplay effects on young children. ..
  6. ALCOHOL USE DISORDER IN YOUNG WOMEN: GENETIC EPIDEMIOLOGY: MOAFTS WAVE 7
    Andrew Heath; Fiscal Year: 2009
    ....
  7. Molecular Epidemiology of Alcoholism 3 - EDAC Families
    Andrew Heath; Fiscal Year: 2005
    ....
  8. ALCOHOLISM: GENETIC EPIDEMIOLOGIC TWIN STUDY
    Andrew Heath; Fiscal Year: 2004
    ..abstract_text> ..
  9. ALCOHOL USE DISORDER IN YOUNG WOMEN: GENETIC EPIDEMIOLOGY: MOAFTS WAVE 7
    Andrew C Heath; Fiscal Year: 2010
    ....