Elizabeth Haswell

Summary

Affiliation: Washington University in Saint Louis
URL: http://biology4.wustl.edu/faculty/haswell/

Publications

  1. request reprint
    Haswell E. Gravity perception: how plants stand up for themselves. Curr Biol. 2003;13:R761-3 pubmed
  2. request reprint
    Haswell E, Meyerowitz E. MscS-like proteins control plastid size and shape in Arabidopsis thaliana. Curr Biol. 2006;16:1-11 pubmed
    ..We propose that MscS family members have evolved new roles in plants since the endosymbiotic event that gave rise to plastids. ..
  3. Haswell E, Phillips R, Rees D. Mechanosensitive channels: what can they do and how do they do it?. Structure. 2011;19:1356-69 pubmed publisher
    ....
  4. Maksaev G, Haswell E. Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes. J Gen Physiol. 2011;138:641-9 pubmed publisher
    ..Furthermore, MscS can now be compared directly to its eukaryotic homologues or to other mechanosensitive channels that are not easily studied in E. coli. ..
  5. Haswell E, Peyronnet R, Barbier Brygoo H, Meyerowitz E, Frachisse J. Two MscS homologs provide mechanosensitive channel activities in the Arabidopsis root. Curr Biol. 2008;18:730-734 pubmed publisher
    ..This is the first molecular identification and characterization of MS channels in plant membranes. ..
  6. Peyronnet R, Haswell E, Barbier Brygoo H, Frachisse J. AtMSL9 and AtMSL10: Sensors of plasma membrane tension in Arabidopsis roots. Plant Signal Behav. 2008;3:726-9 pubmed
    ..2,7,8 MscS homolgues have not yet been identified in animals. ..
  7. Wilson M, Jensen G, Haswell E. Two mechanosensitive channel homologs influence division ring placement in Arabidopsis chloroplasts. Plant Cell. 2011;23:2939-49 pubmed publisher
    ..These results establish MS channels as components of the chloroplast division machinery and suggest that their role is evolutionarily conserved. ..
  8. Veley K, Maksaev G, Frick E, January E, Kloepper S, Haswell E. Arabidopsis MSL10 has a regulated cell death signaling activity that is separable from its mechanosensitive ion channel activity. Plant Cell. 2014;26:3115-31 pubmed publisher
    ..These findings further our understanding of the evolution and significance of mechanosensitive ion channels. ..
  9. Haswell E, Verslues P. The ongoing search for the molecular basis of plant osmosensing. J Gen Physiol. 2015;145:389-94 pubmed publisher
  10. Hamilton E, Jensen G, Maksaev G, Katims A, Sherp A, Haswell E. Mechanosensitive channel MSL8 regulates osmotic forces during pollen hydration and germination. Science. 2015;350:438-41 pubmed publisher
    ..These data further suggest that homologs of bacterial MscS have been repurposed in eukaryotes to function as mechanosensors in multiple developmental and environmental contexts. ..

Detail Information

Publications13

  1. request reprint
    Haswell E. Gravity perception: how plants stand up for themselves. Curr Biol. 2003;13:R761-3 pubmed
  2. request reprint
    Haswell E, Meyerowitz E. MscS-like proteins control plastid size and shape in Arabidopsis thaliana. Curr Biol. 2006;16:1-11 pubmed
    ..We propose that MscS family members have evolved new roles in plants since the endosymbiotic event that gave rise to plastids. ..
  3. Haswell E, Phillips R, Rees D. Mechanosensitive channels: what can they do and how do they do it?. Structure. 2011;19:1356-69 pubmed publisher
    ....
  4. Maksaev G, Haswell E. Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes. J Gen Physiol. 2011;138:641-9 pubmed publisher
    ..Furthermore, MscS can now be compared directly to its eukaryotic homologues or to other mechanosensitive channels that are not easily studied in E. coli. ..
  5. Haswell E, Peyronnet R, Barbier Brygoo H, Meyerowitz E, Frachisse J. Two MscS homologs provide mechanosensitive channel activities in the Arabidopsis root. Curr Biol. 2008;18:730-734 pubmed publisher
    ..This is the first molecular identification and characterization of MS channels in plant membranes. ..
  6. Peyronnet R, Haswell E, Barbier Brygoo H, Frachisse J. AtMSL9 and AtMSL10: Sensors of plasma membrane tension in Arabidopsis roots. Plant Signal Behav. 2008;3:726-9 pubmed
    ..2,7,8 MscS homolgues have not yet been identified in animals. ..
  7. Wilson M, Jensen G, Haswell E. Two mechanosensitive channel homologs influence division ring placement in Arabidopsis chloroplasts. Plant Cell. 2011;23:2939-49 pubmed publisher
    ..These results establish MS channels as components of the chloroplast division machinery and suggest that their role is evolutionarily conserved. ..
  8. Veley K, Maksaev G, Frick E, January E, Kloepper S, Haswell E. Arabidopsis MSL10 has a regulated cell death signaling activity that is separable from its mechanosensitive ion channel activity. Plant Cell. 2014;26:3115-31 pubmed publisher
    ..These findings further our understanding of the evolution and significance of mechanosensitive ion channels. ..
  9. Haswell E, Verslues P. The ongoing search for the molecular basis of plant osmosensing. J Gen Physiol. 2015;145:389-94 pubmed publisher
  10. Hamilton E, Jensen G, Maksaev G, Katims A, Sherp A, Haswell E. Mechanosensitive channel MSL8 regulates osmotic forces during pollen hydration and germination. Science. 2015;350:438-41 pubmed publisher
    ..These data further suggest that homologs of bacterial MscS have been repurposed in eukaryotes to function as mechanosensors in multiple developmental and environmental contexts. ..
  11. Wilson M, Mixdorf M, Berg R, Haswell E. Plastid osmotic stress influences cell differentiation at the plant shoot apex. Development. 2016;143:3382-93 pubmed publisher
    ..These results are consistent with a model wherein the cytokinin/WUS pathway and retrograde signaling control cell differentiation at the shoot apex. ..
  12. Hamant O, Haswell E. Life behind the wall: sensing mechanical cues in plants. BMC Biol. 2017;15:59 pubmed publisher
    ..What about plant systems? Our goal in this review is to summarize what is known about the perception of mechanical cues in plants, and to provide a brief comparison with animals. ..
  13. Basu D, Haswell E. Plant mechanosensitive ion channels: an ocean of possibilities. Curr Opin Plant Biol. 2017;40:43-48 pubmed publisher
    ..Inspired by recent discoveries in bacterial and animal systems, we are beginning to establish the conserved and the unique ways in which mechanosensitive channels function in plants. ..