JAMES HARBOUR

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Molecular basis of low-penetrance retinoblastoma
    J W Harbour
    Washington University, Campus Box 8069, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 119:1699-704. 2001
  2. ncbi request reprint Photodynamic therapy for choroidal metastasis from carcinoid tumor
    J William Harbour
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 137:1143-5. 2004
  3. pmc Association between choroidal pigmentation and posterior uveal melanoma in a white population
    J W Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8069, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Br J Ophthalmol 88:39-43. 2004
  4. ncbi request reprint Transpupillary thermotherapy versus plaque radiotherapy for suspected choroidal melanomas
    J William Harbour
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Ophthalmology 110:2207-14; discussion 2215. 2003
  5. pmc Frequent mutation of BAP1 in metastasizing uveal melanomas
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Science 330:1410-3. 2010
  6. pmc Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi
    J W Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8069, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Br J Ophthalmol 88:36-8. 2004
  7. ncbi request reprint Rate of resolution of exudative retinal detachment after plaque radiotherapy for uveal melanoma
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, PO Box 8069, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 120:1463-9. 2002
  8. ncbi request reprint Transducible peptide therapy for uveal melanoma and retinoblastoma
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8069, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 120:1341-6. 2002
  9. ncbi request reprint Altered expression of Rb and p53 in uveal melanomas following plaque radiotherapy
    Milam A Brantley
    Center for Ocular Oncology, Department of Ophthalmology and Visual Sciences and Division of Molecular Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 133:242-8. 2002
  10. doi request reprint A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Cancer Res 14:3737-45. 2008

Research Grants

  1. Molecular Predictive Testing in Ocular Melanoma
    JAMES HARBOUR; Fiscal Year: 2009
  2. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2009
  3. Molecular Predictive Testing in Ocular Melanoma
    JAMES HARBOUR; Fiscal Year: 2007
  4. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2007
  5. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2004
  6. Molecular Predictive Testing in Ocular Melanoma
    JAMES W HARBOUR; Fiscal Year: 2010

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Molecular basis of low-penetrance retinoblastoma
    J W Harbour
    Washington University, Campus Box 8069, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 119:1699-704. 2001
    ..Low-penetrance retinoblastoma mutations either cause a reduction in the amount of normal pRB that is produced (class 1 mutations) or result in a partially functional mutant pRB (class 2 mutations)...
  2. ncbi request reprint Photodynamic therapy for choroidal metastasis from carcinoid tumor
    J William Harbour
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 137:1143-5. 2004
    ..To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy...
  3. pmc Association between choroidal pigmentation and posterior uveal melanoma in a white population
    J W Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8069, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Br J Ophthalmol 88:39-43. 2004
    ..It is well known that light skin pigmentation is a risk factor for cutaneous melanoma. The aim of this study was to investigate the analogous association between choroidal pigmentation and posterior uveal melanoma...
  4. ncbi request reprint Transpupillary thermotherapy versus plaque radiotherapy for suspected choroidal melanomas
    J William Harbour
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Ophthalmology 110:2207-14; discussion 2215. 2003
    ..To examine the outcomes and complications of transpupillary thermotherapy for treatment of small choroidal melanomas...
  5. pmc Frequent mutation of BAP1 in metastasizing uveal melanomas
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Science 330:1410-3. 2010
    ..These findings implicate loss of BAP1 in uveal melanoma metastasis and suggest that the BAP1 pathway may be a valuable therapeutic target...
  6. pmc Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi
    J W Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8069, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Br J Ophthalmol 88:36-8. 2004
    ..To investigate the association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi...
  7. ncbi request reprint Rate of resolution of exudative retinal detachment after plaque radiotherapy for uveal melanoma
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, PO Box 8069, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 120:1463-9. 2002
    ..To determine the clinical relevance of exudative retinal detachment (ERD) and the rate of ERD resolution after plaque radiotherapy of posterior uveal melanomas...
  8. ncbi request reprint Transducible peptide therapy for uveal melanoma and retinoblastoma
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8069, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 120:1341-6. 2002
    ..To determine whether transducible peptides that inhibit the oncoproteins HDM2 and Bcl-2 may selectively kill uveal melanoma and retinoblastoma cells...
  9. ncbi request reprint Altered expression of Rb and p53 in uveal melanomas following plaque radiotherapy
    Milam A Brantley
    Center for Ocular Oncology, Department of Ophthalmology and Visual Sciences and Division of Molecular Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 133:242-8. 2002
    ..To examine the expression of proteins in the Rb and p53 tumor suppressor pathways in uveal melanomas following plaque radiotherapy...
  10. doi request reprint A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Cancer Res 14:3737-45. 2008
    ....
  11. pmc An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    J Mol Diagn 12:461-8. 2010
    ..This prognostic assay provides an important addition to the armamentarium for managing patients with uveal melanoma, and it provides a proof of principle for the development of similar assays for other cancers...
  12. ncbi request reprint Lipid exudation following plaque radiotherapy for posterior uveal melanoma
    Michael D Mills
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Am J Ophthalmol 141:594-595. 2006
    ..To investigate factors associated with lipid exudation after plaque radiotherapy for uveal melanoma...
  13. doi request reprint Loss of Id2 potentiates the tumorigenic effect of Rb inactivation in a mouse model of retinoblastoma
    Solange Landreville
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Curr Eye Res 35:435-9. 2010
    ..The role of Id2 has not yet been investigated in the prototype cancer Rb-defective cancer, retinoblastoma itself. This study investigated whether loss of Id2 modified the effects of Rb inactivation in a mouse model of retinoblastoma...
  14. doi request reprint Molecular prognostic testing and individualized patient care in uveal melanoma
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 148:823-9.e1. 2009
    ..To critically assess the status of molecular prognostic testing and its use for individualized patient care in uveal melanoma...
  15. pmc Eye cancer: unique insights into oncogenesis: the Cogan Lecture
    J William Harbour
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Invest Ophthalmol Vis Sci 47:1736-45. 2006
  16. pmc Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens
    Michael D Onken
    Box 8096, 660 South Euclid Ave, St Louis, MO 63124, USA
    J Mol Diagn 8:567-73. 2006
    ..This method can be applied to specimens obtained from distant geographic locations and can stratify uveal melanoma patients based on metastatic risk...
  17. pmc Emerging insights into the molecular pathogenesis of uveal melanoma
    Solange Landreville
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Future Oncol 4:629-36. 2008
    ..Taken together, this pathogenetic scheme can be used to construct a molecularly based and prognostically relevant classification of uveal melanomas that can be used clinically for personalized patient management...
  18. ncbi request reprint Functional analysis of the p53 pathway in response to ionizing radiation in uveal melanoma
    Young Sun
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO, USA
    Invest Ophthalmol Vis Sci 46:1561-4. 2005
    ..The current study was conducted to analyze the functional integrity of the p53 pathway in primary uveal melanoma cells...
  19. ncbi request reprint Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Cancer Res 64:7205-9. 2004
    ..These studies offer new insights into melanoma pathogenesis, and they provide a practical foundation for effective clinical predictive testing...
  20. ncbi request reprint Pars plana vitrectomy in eyes containing a treated posterior uveal melanoma
    William J Foster
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, and Barnes Retina Institute, St Louis, Missouri 63110, USA
    Am J Ophthalmol 136:471-6. 2003
    ..To determine the safety of pars plana vitrectomy in eyes containing a treated posterior uveal melanoma...
  21. doi request reprint Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling
    Lori A Worley
    Department of Ophthalmology and Visual Sciences and Siteman Comprehensive Cancer Center, Washington University School of Medicine, St Louis, Missouri, USA
    Melanoma Res 18:184-90. 2008
    ..miRNA expression may represent a highly accurate biomarker for metastatic risk in uveal melanoma. In addition, these results may provide new insights into the role of miRNAs in tumor progression and the metastatic phenotype...
  22. ncbi request reprint Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer Res 66:4602-9. 2006
    ..These findings reveal new roles for Id2 and E-cadherin in uveal melanoma progression, and they identify potential targets for therapeutic intervention...
  23. doi request reprint Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis
    Shu Hong Chang
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Melanoma Res 18:191-200. 2008
    ....
  24. ncbi request reprint DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma
    Justis P Ehlers
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Cancer Res 11:3609-13. 2005
    ..In this profile, a cluster of genes at chromosome 8q was overexpressed in high-grade tumors, providing an opportunity to search for potential oncogenes in this region...
  25. ncbi request reprint Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma
    Lori A Worley
    Department of Ophthalmology and Visual Sciences, Washington University, St Louis, Missouri 63110, USA
    Clin Cancer Res 13:1466-71. 2007
    ..To compare a gene expression-based classifier versus the standard genetic prognostic marker, monosomy 3, for predicting metastasis in uveal melanoma...
  26. doi request reprint Tilting of radioactive plaques after initial accurate placement for treatment of uveal melanoma
    Arghavan Almony
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Ophthalmol 126:65-70. 2008
    ..To evaluate plaque movement as a potential factor in local failure using intraoperative ultrasonography at plaque insertion and removal...
  27. ncbi request reprint NBS1 expression as a prognostic marker in uveal melanoma
    Justis P Ehlers
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Clin Cancer Res 11:1849-53. 2005
    ..Here, we use microarray gene expression data to identify a new prognostic marker...
  28. ncbi request reprint Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase
    Jonathan H Lieman
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 South Euclid Ave, St Louis, Missouri 63110, USA
    J Biol Chem 280:10484-90. 2005
    ..These findings reveal a new mechanistic link between Rb-E2F and the extrinsic (caspase 8-mediated) apoptotic pathway...
  29. ncbi request reprint Optical coherence tomography in the evaluation of retinal changes associated with suspicious choroidal melanocytic tumors
    Gabriella Espinoza
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences and Barnes Retina Institute, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 137:90-5. 2004
    ..This study investigates optical coherence tomography (OCT) in evaluating SRF in suspicious choroidal melanocytic tumors...
  30. pmc Oncogenic mutations in GNAQ occur early in uveal melanoma
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Invest Ophthalmol Vis Sci 49:5230-4. 2008
    ..An extensive search for such mutations was undertaken, focusing on the RAF/MEK/ERK pathway, which is often the target of initiating mutations in other types of cancer...
  31. doi request reprint Hepatic metastasis from uveal melanoma: angiographic pattern predictive of survival after hepatic arterial chemoembolization
    Pouya N Dayani
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Ophthalmol 127:628-32. 2009
    ..To identify clinical features associated with survival after hepatic arterial chemoembolization (HACE) for uveal melanoma metastasis...
  32. ncbi request reprint Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Ophthalmol 140:748-9. 2005
    ..To determine whether there is an association between gene expression profile and looping extravascular matrix patterns in primary uveal melanomas...
  33. pmc Association between gene expression profile, proliferation and metastasis in uveal melanoma
    Michael D Onken
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Curr Eye Res 35:857-63. 2010
    ..Towards such an explanation, this study was conducted to determine whether class 2 tumors have a higher proliferative rate than class 1 tumors...
  34. ncbi request reprint Status of the NF1 tumor suppressor locus in uveal melanoma
    William J Foster
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Ophthalmol 121:1311-5. 2003
    ..A clinical association has been observed between uveal melanoma and neurofibromatosis type 1 (NF1). This study aims to determine whether the NF1 tumor suppressor gene is mutated in uveal melanoma...
  35. doi request reprint Review of 676 second primary tumors in patients with retinoblastoma: association between age at onset and tumor type
    Kyung In Woo
    Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Ophthalmol 128:865-70. 2010
    ..To obtain a more accurate understanding of second primary tumors (SPTs) by analyzing a large number of SPTs from the published literature...
  36. ncbi request reprint Hepatic arterial chemoembolization for management of metastatic melanoma
    Karun V Sharma
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA
    AJR Am J Roentgenol 190:99-104. 2008
    ..However, the reports of outcomes are limited. We present our outcomes with hepatic arterial chemoembolization for metastasis of stage 4 melanoma...
  37. pmc MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A
    Amy E Loercher
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    J Cell Biol 168:35-40. 2005
    ....
  38. ncbi request reprint Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb
    Duanduan Ma
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 278:19358-66. 2003
    ..As a survival strategy, some cancer cells may exploit this dual role of Rb by phosphorylating sites that regulate tumor suppression but avoiding phosphorylation of Ser567 and consequent apoptotic stimulus...
  39. ncbi request reprint Fine needle aspiration biopsy with adjunct immunohistochemistry in intraocular tumor management
    Beverly E Faulkner-Jones
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Acta Cytol 49:297-308. 2005
    ..To assess the effectiveness of fine needle aspiration biopsy (FNAB), with and without immunohistochemistry (IHC), in the management of solid intraocular tumors...
  40. ncbi request reprint Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma
    Michael D Onken
    Department of Ophthalmology, Washington University, St Louis, Missouri, USA
    Clin Cancer Res 13:2923-7. 2007
    ..It is not known whether techniques that identify loss of heterozygosity for chromosome 3 predict metastasis more accurately than those that detect only numerical loss of chromosome 3 (monosomy 3)...
  41. ncbi request reprint Molecular genetics of uveal melanoma
    Amy E Loercher
    Department of Ophthalmology and Visual Sciences, Washington University, School of Medicine, St Louis, MO 63110, USA
    Curr Eye Res 27:69-74. 2003
    ..Herein, we review the findings to date, discuss the insights they provide, and suggest future directions for molecular research in uveal melanoma...
  42. ncbi request reprint Ocular melanoma: a review and the relationship to cutaneous melanoma
    Eva A Hurst
    Division of Dermatology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Dermatol 139:1067-73. 2003
    ..We review the incidence and characteristics of OM, evaluate the existent data regarding its potential relationship to CM, and provide some guidance for the dermatologist regarding the evaluation and diagnosis of this ocular tumor...
  43. doi request reprint Id2 deficiency promotes metastasis in a mouse model of ocular cancer
    Olga A Agapova
    Department of Ophthalmology and Visual Sciences and Siteman Cancer Center, Washington University School of Medicine, Campus Box 8096, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Clin Exp Metastasis 27:91-6. 2010
    ..These findings provide new insights into the role of Id2 in metastasis...
  44. ncbi request reprint Rb at the interface between cell cycle and apoptotic decisions
    Rachel B Delston
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Curr Mol Med 6:713-8. 2006
    ..For many of these studies, we have chosen the melanocyte lineage as a model cell system because of the established role for Rb in melanocyte differentiation and survival, and the frequent deregulation of the Rb pathway in melanoma...
  45. ncbi request reprint Risk factors for metastasis in retinoblastoma
    Paul T Finger
    The New York Eye Cancer Center, New York, NY, USA
    Surv Ophthalmol 47:1-16. 2002
    ..This review has been performed to help those caring for patients with retinoblastoma and to aid informed consent...
  46. ncbi request reprint Photodynamic therapy for circumscribed choroidal hemangioma
    Tom G Sheidow
    Ivey Eye Institute, Department of Ophthalmology, University of Western Ontario, London
    Can J Ophthalmol 37:314-7. 2002
  47. ncbi request reprint What is the best treatment for retinoblastoma?
    J William Harbour
    Am J Ophthalmol 138:471-3. 2004
  48. ncbi request reprint Molecular prognostic testing in uveal melanoma: has it finally come of age?
    J William Harbour
    Arch Ophthalmol 125:1122-3. 2007
  49. ncbi request reprint For whom the bell tolls: susceptibility to common adult cancers in retinoblastoma survivors
    Frederic J Kaye
    J Natl Cancer Inst 96:342-3. 2004
  50. doi request reprint Integrative genomic analysis of aneuploidy in uveal melanoma
    Justis P Ehlers
    Wills Eye Hospital, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 14:115-22. 2008
    ..Uveal melanoma is an attractive solid tumor for studying aneuploidy because it is a relatively homogeneous cancer that is highly metastatic and has low nonspecific chromosomal instability...
  51. ncbi request reprint Molecular pathobiology of uveal melanoma
    Justis P Ehlers
    Willis Eye Hospital, Philadelphia, PA 19107, USA
    Int Ophthalmol Clin 46:167-80. 2006
  52. ncbi request reprint Uveal melanoma: genetic aspects
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute i3 129, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:85-97, viii. 2005
    ..This article reviews the clinical genetics, cytogenetics, and molecular genetic aspects of uveal melanoma...
  53. ncbi request reprint Inhibiting angiogenesis in retinoblastoma
    Rajendra S Apte
    Ophthalmic Res 39:188-90. 2007

Research Grants13

  1. Molecular Predictive Testing in Ocular Melanoma
    JAMES HARBOUR; Fiscal Year: 2009
    ....
  2. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2009
    ..Consequently, these aims are highly relevant to the vision statement of the NEI, and they address several major program goals and objectives of the Retinal Diseases Program. ..
  3. Molecular Predictive Testing in Ocular Melanoma
    JAMES HARBOUR; Fiscal Year: 2007
    ....
  4. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2007
    ..Consequently, these aims are highly relevant to the vision statement of the NEI, and they address several major program goals and objectives of the Retinal Diseases Program. ..
  5. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2004
    ..abstract_text> ..
  6. Molecular Predictive Testing in Ocular Melanoma
    JAMES W HARBOUR; Fiscal Year: 2010
    ..This research proposal represents an application of this strategy and provides a proof of principle for similar approaches in other cancers. ..