Julia D Grant

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint A comparison of the latent class structure of cannabis problems among adult men and women who have used cannabis repeatedly
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 101:1133-42. 2006
  2. ncbi request reprint Subjective reactions to cocaine and marijuana are associated with abuse and dependence
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, 40 N Kingshighway, Suite 3, St Louis, MO 63108, United States
    Addict Behav 30:1574-86. 2005
  3. ncbi request reprint Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychol Med 36:109-18. 2006
  4. ncbi request reprint Spousal concordance for alcohol dependence: evidence for assortative mating or spousal interaction effects?
    Julia D Grant
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 31:717-28. 2007
  5. pmc Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO 63106, USA
    Addict Behav 37:240-7. 2012
  6. pmc Common genetic contributions to alcohol and cannabis use and dependence symptomatology
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 34:545-54. 2010
  7. pmc Associations of alcohol, nicotine, cannabis, and drug use/dependence with educational attainment: evidence from cotwin-control analyses
    Julia D Grant
    Midwest Alcoholism Research Center at Washington University, Washington University School of Medicine, St Louis, Missouri, USA
    Alcohol Clin Exp Res 36:1412-20. 2012
  8. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
  9. pmc Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 33:2047-56. 2009
  10. pmc Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression
    Carolyn E Sartor
    Department of Psychiatry, Yale School of Medicine, VA Connecticut Healthcare System, USA
    Arch Gen Psychiatry 69:293-9. 2012

Detail Information

Publications47

  1. ncbi request reprint A comparison of the latent class structure of cannabis problems among adult men and women who have used cannabis repeatedly
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 101:1133-42. 2006
    ..Current evidence is not conclusive regarding gender differences for cannabis use, abuse and dependence. It is not known if symptom profiles differ by gender...
  2. ncbi request reprint Subjective reactions to cocaine and marijuana are associated with abuse and dependence
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, 40 N Kingshighway, Suite 3, St Louis, MO 63108, United States
    Addict Behav 30:1574-86. 2005
    ..7; 95% CI: 5.6-62.6) classes. We found evidence for both qualitative and quantitative subjective effect profiles. Subjective effects, both positive and adverse are associated with lifetime risk for marijuana and cocaine dependence...
  3. ncbi request reprint Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychol Med 36:109-18. 2006
    ..Early alcohol use is associated with abuse and dependence of licit and illicit substances later in life. The role of genetic and environmental factors in this association is not conclusive...
  4. ncbi request reprint Spousal concordance for alcohol dependence: evidence for assortative mating or spousal interaction effects?
    Julia D Grant
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 31:717-28. 2007
    ..The primary goal of the present analyses is to test hypotheses about the source(s) and magnitude of spousal associations for AD using a twin-spouse design...
  5. pmc Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO 63106, USA
    Addict Behav 37:240-7. 2012
    ..Smoking interventions may have greatest impact by targeting smoking prevention among peer groups in adolescent and young adult populations...
  6. pmc Common genetic contributions to alcohol and cannabis use and dependence symptomatology
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 34:545-54. 2010
    ....
  7. pmc Associations of alcohol, nicotine, cannabis, and drug use/dependence with educational attainment: evidence from cotwin-control analyses
    Julia D Grant
    Midwest Alcoholism Research Center at Washington University, Washington University School of Medicine, St Louis, Missouri, USA
    Alcohol Clin Exp Res 36:1412-20. 2012
    ..We tested whether alcohol, nicotine, and illicit drug use and dependence were associated with lifetime educational attainment after controlling for familial background characteristics...
  8. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
    ..A high genetic correlation between these measures would suggest that a continuous measure of consumption may have a useful role in the discovery of genes contributing to dependence risk...
  9. pmc Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 33:2047-56. 2009
    ..In this study, we examine whether age at first drink moderates genetic and environmental influences, via gene x environment interactions, on DSM-IV alcohol dependence symptoms...
  10. pmc Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression
    Carolyn E Sartor
    Department of Psychiatry, Yale School of Medicine, VA Connecticut Healthcare System, USA
    Arch Gen Psychiatry 69:293-9. 2012
    ....
  11. pmc Contribution of parental psychopathology to offspring smoking and nicotine dependence in a genetically informative design
    Hong Xian
    Research Service 151JC, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, Missouri 63106, USA
    J Stud Alcohol Drugs 71:664-73. 2010
    ....
  12. pmc Initial response to cigarettes predicts rate of progression to regular smoking: findings from an offspring-of-twins design
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, Saint Louis, Missouri 63110, USA
    Addict Behav 35:771-8. 2010
    ..exclusively negative (physiological) responses suggests the importance of considering both dimensions in combination to characterize risk for smoking-related outcomes...
  13. pmc A latent class analysis of DSM-IV and Fagerström (FTND) criteria for nicotine dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Nicotine Tob Res 13:972-81. 2011
    ....
  14. pmc Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring
    Vivia V McCutcheon
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8134, St Louis, MO 63110, USA
    Drug Alcohol Depend 128:20-9. 2013
    ..The present study examines the clustering of offspring lifetime substance use and psychiatric disorders into subtypes and characterizes them in terms of familial and non-familial influences using an offspring-of-twins design...
  15. pmc Subjective effects to cannabis are associated with use, abuse and dependence after adjusting for genetic and environmental influences
    Jeffrey F Scherrer
    Research Service, St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO, United States
    Drug Alcohol Depend 105:76-82. 2009
    ..This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder...
  16. doi request reprint Genetic and environmental contributions to nicotine, alcohol and cannabis dependence in male twins
    Hong Xian
    Research Service, St Louis Veterans Affairs Medical Center VAMC, St Louis, MO 63106, USA
    Addiction 103:1391-8. 2008
    ..To compute the common and specific genetic and environmental contributions to nicotine dependence (ND) alcohol dependence (AD) and cannabis dependence (CD)...
  17. pmc Patterns of use, sequence of onsets and correlates of tobacco and cannabis
    Arpana Agrawal
    Washington University School of Medicine, Dept of Psychiatry and the Midwest Alcoholism Research Center, Saint Louis, MO 63110, USA
    Addict Behav 36:1141-7. 2011
    ..In this study, we characterize patterns of cannabis and tobacco use (tobacco but not cannabis, cannabis but not tobacco or both) and compare the factors associated with onset of tobacco before cannabis and cannabis before tobacco...
  18. ncbi request reprint Risk for initiation of substance use as a function of age of onset of cigarette, alcohol and cannabis use: findings in a Midwestern female twin cohort
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Prev Med 43:125-8. 2006
    ..We investigated whether use and early-onset use of cigarettes, alcohol and cannabis contributed an increase in risk for initiation of subsequent psychoactive substances in women (N = 3729, mean age = 21.7)...
  19. pmc Measured environmental contributions to cannabis abuse/dependence in an offspring of twins design
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO 63106, USA
    Addict Behav 33:1255-66. 2008
    ..08). Perceived sibling, friend and school peer substance use are strongly associated with CAD in young adults even after accounting for latent familial risk and for multiple measured intra-family and extra-family environmental influences...
  20. pmc Childhood sexual abuse and early substance use in adolescent girls: the role of familial influences
    Carolyn E Sartor
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Addiction 108:993-1000. 2013
    ..To assess the extent to which the association between childhood sexual abuse (CSA) and early use of alcohol, cigarettes and cannabis in adolescent girls is mediated by risk factors that tend to cluster in families where CSA occurs...
  21. pmc Deconstructing the age-prevalence curve of alcohol dependence: why "maturing out" is only a small piece of the puzzle
    Alvaro Vergés
    Department of Psychological Sciences, University of Missouri Columbia, Midwest Alcoholism Research Center, Columbia, MO, USA
    J Abnorm Psychol 121:511-23. 2012
    ....
  22. pmc Genetic and environmental contributions to BMI in adolescent and young adult women
    Alexis E Duncan
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Obesity (Silver Spring) 17:1040-3. 2009
    ..Additional research is needed to better characterize the environmental and genetic factors related to BMI in persons of different races to aid understanding of the complex determinants of body weight in individuals...
  23. ncbi request reprint Stimulant use and symptoms of abuse/dependence: epidemiology and associations with cannabis use--a twin study
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Rd, Suite 1000, St Louis, MO 63110, United States
    Drug Alcohol Depend 86:147-53. 2007
    ....
  24. ncbi request reprint Subtypes of illicit drug users: a latent class analysis of data from an Australian twin sample
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, United States of America
    Twin Res Hum Genet 9:523-30. 2006
    ..Aggregation of population-level data may obscure important subgroup differences in patterns of illicit drug use and psychiatric comorbidity. Further exploration of a 'self-medicating' subgroup is needed...
  25. pmc The effects of maternal smoking during pregnancy on offspring outcomes
    Arpana Agrawal
    Washington University School of Medicine, Dept of Psychiatry, Saint Louis, MO 63110, USA
    Prev Med 50:13-8. 2010
    ....
  26. pmc H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence
    Elliot C Nelson
    Department of Psychiatry, Washington University School of Medicine, USA
    Addict Biol 15:1-11. 2010
    ..Our results also suggest that severe early trauma may prove to be an important clinical covariate in the treatment of alcohol dependence...
  27. pmc Psychiatric and familial predictors of transition times between smoking stages: results from an offspring-of-twins study
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addict Behav 33:235-51. 2008
    ..Findings characterize a rarely examined aspect of the course of ND development and highlight critical distinctions in risk profiles across stages of tobacco involvement...
  28. pmc A cotwin-control analysis of drug use and abuse/dependence risk associated with early-onset cannabis use
    Julia D Grant
    The Midwest Alcoholism Research Center at Washington University, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addict Behav 35:35-41. 2010
    ..In contrast to previous research, there is limited evidence for increased risk associated with early-onset use in this sample of Vietnam-era veterans...
  29. pmc Relationship between body mass index, alcohol use, and alcohol misuse in a young adult female twin sample
    Alexis E Duncan
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 70:458-66. 2009
    ..The aim of this study was to examine the relationships between body mass index (BMI) and alcohol use and misuse in young adulthood in a sample of black and white female twins...
  30. pmc A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 70:513-8. 2011
    ....
  31. ncbi request reprint Assortative mating for cigarette smoking and for alcohol consumption in female Australian twins and their spouses
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, 8134, St Louis, MO 63110, USA
    Behav Genet 36:553-66. 2006
    ..We aim to clarify the mechanisms contributing to spousal similarity for cigarette smoking and alcohol consumption...
  32. pmc Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Avenue, Box 8134, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 70:157-68. 2009
    ..The purpose of this study was to develop a quantitative measure of alcohol consumption for gene-mapping studies...
  33. ncbi request reprint Duration of cannabis use--a novel phenotype?
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Rd, Suite 1000, St Louis, MO 63110, United States
    Addict Behav 31:984-94. 2006
    ..While there were high genetic correlations in both women and men, lifetime duration of cannabis may be uniquely informative in assessing components of liability to cannabis use...
  34. pmc The interpretability of family history reports of alcoholism in general community samples: findings in a midwestern U.S. twin birth cohort
    Mary Waldron
    School of Education, Indiana University, Bloomington, IN 47405, USA
    Alcohol Clin Exp Res 36:1091-8. 2012
    ..Although there is a long tradition in alcoholism research of using family history ratings, the interpretability of family history reports of alcoholism from general community samples has yet to be established...
  35. pmc The association between cannabis abuse and dependence and childhood physical and sexual abuse: evidence from an offspring of twins design
    Alexis E Duncan
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 103:990-7. 2008
    ....
  36. pmc A candidate gene association study of alcohol consumption in young women
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Alcohol Clin Exp Res 35:550-8. 2011
    ..We used data on a previously defined alcohol consumption factor score in a sample of 827 young women to investigate association with 1,014 single-nucleotide polymorphisms in genes related to addiction...
  37. ncbi request reprint Psychiatric comorbidity and progression in drug use in adult male twins: implications for the design of genetic association studies
    Alexandre A Todorov
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, MO 63110 1502, United States
    Addict Behav 31:948-61. 2006
    ..We use the result of these analyses to show how the use of a particular drug disorder phenotype for selecting cases could impact final sample composition...
  38. doi request reprint Parental separation and early substance involvement: Results from children of alcoholic and cannabis dependent twins
    Mary Waldron
    Department of Counseling and Educational Psychology, Indiana University School of Education, Bloomington, IN, United States Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO, United States Electronic address
    Drug Alcohol Depend 134:78-84. 2014
    ..We examined early substance involvement as a function of parental separation during childhood and parental alcohol and cannabis dependence...
  39. pmc A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families
    Michele L Pergadia
    Department of Psychiatry, WashingtonUniversity School of Medicine, Saint Louis, MO 63110, USA
    Am J Psychiatry 168:848-52. 2011
    ..The authors tested for genetic linkage of DSM-IV-diagnosed major depressive disorder in families that were ascertained for cigarette smoking...
  40. pmc Heritability of delay discounting in adolescence: a longitudinal twin study
    Andrey P Anokhin
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Behav Genet 41:175-83. 2011
    ..This study provides the first evidence for heritability of DD in humans and suggests that DD can be a promising endophenotype for genetic studies of addiction and externalizing disorders...
  41. pmc A twin study of alcohol dependence, binge eating, and compensatory behaviors
    Melissa A Munn-Chernoff
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 74:664-73. 2013
    ..We investigated genetic and environmental correlations among alcohol dependence, binge eating, and compensatory behaviors in male and female twins...
  42. pmc Age and ethnic differences in the onset, persistence and recurrence of alcohol use disorder
    Julia D Grant
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 107:756-65. 2012
    ..To estimate ethnic differences in three components of alcohol use disorder and alcohol dependence course (onset, persistence and recurrence) in a developmental framework...
  43. pmc Suicidal behavior, smoking, and familial vulnerability
    Jeffrey F Scherrer
    Research Service 151 JC, St Louis Veterans Affairs Medical Center, St Louis, MO, USA
    Nicotine Tob Res 14:415-24. 2012
    ..Smoking is a well-established correlate of suicidal behavior. It is not known if familial risk factors contribute to this association...
  44. pmc Developmental and genetic influences on prefrontal function in adolescents: a longitudinal twin study of WCST performance
    Andrey P Anokhin
    Washington University School of Medicine, St Louis, MO 63110, USA
    Neurosci Lett 472:119-22. 2010
    ..The results suggest increasing influence of familial factors on frontal executive functioning during adolescence, as well as gender differences in the relative role of genetic and environmental factors...
  45. ncbi request reprint The assessment of peer selection and peer environmental influences on behavior using pairs of siblings or twins
    Pamela A F Madden
    Missouri Alcoholism Research Center, Washington University School, 63108, USA
    Twin Res 5:38-43. 2002
    ..Limitations of these simulations, including uncertainty about the most appropriate way to model peer selection, are discussed...
  46. ncbi request reprint The genetics of middle-age spread in middle-class males
    James C Romeis
    Health Services Research, Department of Health Management and Policy, School of Public Health, Saint Louis University, St Louis, Missouri 63104, USA
    Twin Res 7:596-602. 2004
    ..The data analysis suggests that treatments and public health interventions need to recognize the magnitude of genetic factors if short-term and long-term interventions are to be effective...
  47. ncbi request reprint Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 35:625-35. 2005
    ..Little attention, however, has been directed to investigating the roles of genetic transmission and prenatal exposure simultaneously...