G A Grant

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. Grant G, Schuller D, Banaszak L. A model for the regulation of D-3-phosphoglycerate dehydrogenase, a Vmax-type allosteric enzyme. Protein Sci. 1996;5:34-41 pubmed
    ....
  2. request reprint
    Grant G, Xu X. Probing the regulatory domain interface of D-3-phosphoglycerate dehydrogenase with engineered tryptophan residues. J Biol Chem. 1998;273:22389-94 pubmed
    ....
  3. Grant G, Xu X, Hu Z. The relationship between effector binding and inhibition of activity in D-3-phosphoglycerate dehydrogenase. Protein Sci. 1999;8:2501-5 pubmed
    ..Thus, maximal inhibition is accomplished with less than maximal occupancy of effector sites through a mechanism that displays strong elements of both positive and negative cooperativity. ..

Detail Information

Publications3

  1. Grant G, Schuller D, Banaszak L. A model for the regulation of D-3-phosphoglycerate dehydrogenase, a Vmax-type allosteric enzyme. Protein Sci. 1996;5:34-41 pubmed
    ....
  2. request reprint
    Grant G, Xu X. Probing the regulatory domain interface of D-3-phosphoglycerate dehydrogenase with engineered tryptophan residues. J Biol Chem. 1998;273:22389-94 pubmed
    ....
  3. Grant G, Xu X, Hu Z. The relationship between effector binding and inhibition of activity in D-3-phosphoglycerate dehydrogenase. Protein Sci. 1999;8:2501-5 pubmed
    ..Thus, maximal inhibition is accomplished with less than maximal occupancy of effector sites through a mechanism that displays strong elements of both positive and negative cooperativity. ..