Research Topics
| Mae O GordonSummaryAffiliation: Washington University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucomaMae O Gordon
OHTS Coordinating Center, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8203, 660 South Euclid, St Louis, MO 63110, USA
Arch Ophthalmol 120:714-20; discussion 829-30. 2002....
Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertensionMae O Gordon
OHTS Coordinating Center, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8203, 660 South Euclid, St Louis, MO 63110, USA
Ophthalmology 114:10-9. 2007....- The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucomaMichael A Kass
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
Arch Ophthalmol 120:701-13; discussion 829-30. 2002.... 
Delaying treatment of ocular hypertension: the ocular hypertension treatment studyMichael A Kass
Ocular Hypertension Treatment Study Coordinating Center, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Box 8203, 660 S Euclid Ave, St Louis, MO 63110, USA
Arch Ophthalmol 128:276-87. 2010..To compare the safety and efficacy of earlier vs later treatment in preventing primary open-angle glaucoma (POAG) in individuals with ocular hypertension...- The development of a decision analytic model of changes in mean deviation in people with glaucoma: the COA modelSteven M Kymes
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
Ophthalmology 119:1367-74. 2012..To create and validate a statistical model predicting progression of primary open-angle glaucoma (POAG) assessed by loss of visual field as measured in mean deviation (MD) using 3 landmark studies of glaucoma progression and treatment... - Effect of patient's life expectancy on the cost-effectiveness of treatment for ocular hypertensionSteven M Kymes
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8096, 660 S Euclid Ave, St Louis, MO 63110 1093, USA
Arch Ophthalmol 128:613-8. 2010..To assess the influence of expected life span on the cost-effectiveness of treating ocular hypertension to prevent primary open-angle glaucoma... - The utility of the monocular trial: data from the ocular hypertension treatment studyAnjali M Bhorade
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
Ophthalmology 117:2047-54. 2010..To determine whether adjusting the intraocular pressure (IOP) change of the trial eye for the IOP change of the fellow eye (i.e., monocular trial) is a better assessment of medication response than testing each eye independently... - Changes in the quality-of-life of people with keratoconusSteven M Kymes
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
Am J Ophthalmol 145:611-617. 2008..For this study, we evaluated changes that occurred in V-QoL over seven years of follow-up... - The incidence of retinal vein occlusion in the ocular hypertension treatment studyEdward M Barnett
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
Ophthalmology 117:484-8. 2010..To determine the incidence of retinal vein occlusion (RVO) in the Ocular Hypertension Treatment Study (OHTS)... - Management of ocular hypertension: a cost-effectiveness approach from the Ocular Hypertension Treatment StudySteven M Kymes
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
Am J Ophthalmol 141:997-1008. 2006..There is no consensus on which people with ocular hypertension would benefit from treatment... - The lifetime economic burden of keratoconus: a decision analysis using a markov modelRonald L Rebenitsch
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110 1093, USA
Am J Ophthalmol 151:768-773.e2. 2011..To estimate the expected incremental lifetime cost of treatment of keratoconus compared to the expected cost of the treatment of myopia... - The effect of changes in intraocular pressure on the risk of primary open-angle glaucoma in patients with ocular hypertension: an application of latent class analysisFeng Gao
Division of Biostatistics, Washington University School of Medicine, St, Louis, MO, 63110, USA
BMC Med Res Methodol 12:151. 2012..abstract:.. - Variability of intraocular pressure measurements in observation participants in the ocular hypertension treatment studyAnjali M Bhorade
Washington University School of Medicine, St Louis, Missouri 63110, USA
Ophthalmology 116:717-24. 2009..To describe variability of intraocular pressure (IOP) measurements within the same eye and between right and left eyes over a 60-month period in participants in the Ocular Hypertension Treatment Study... - Baseline factors predictive of incident penetrating keratoplasty in keratoconusMae O Gordon
Division of Biostatistics and the Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
Am J Ophthalmol 142:923-30. 2006..Knowledge of these factors is beneficial to clinicians in patient education and may be useful in disease management... - Effect of measurement order between right and left eyes on intraocular pressure measurementMelike Pekmezci
Department of Ophthalmology, University of California, San Francisco, USA
Arch Ophthalmol 129:276-81. 2011..To determine whether the order of intraocular pressure (IOP) measurement between right and left eyes affects IOP measurement... - The impact of anchor point on utilities for 5 common ophthalmic diseasesBryan S Lee
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri 63110, USA
Ophthalmology 115:898-903.e4. 2008..To elicit utilities on a perfect health and perfect vision scale for 5 common eye diseases... - Quality of life in keratoconusSteven M Kymes
Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
Am J Ophthalmol 138:527-35. 2004..We examined the vision-related quality of life of patients in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study... - Comparison of initial intraocular pressure response with topical beta-adrenergic antagonists and prostaglandin analogues in African American and white individuals in the Ocular Hypertension Treatment StudySteven L Mansberger
Devers Eye Institute Discoveries In Sight, Legacy Health System, Portland, Ore, USA
Arch Ophthalmol 125:454-9. 2007.... - Visual field quality control in the Ocular Hypertension Treatment Study (OHTS)John L Keltner
Department of Ophthalmology and Vision Science, University of California, Davis, CA, USA
J Glaucoma 16:665-9. 2007.... - Changes in central corneal thickness over time: the ocular hypertension treatment studyJames D Brandt
Department of Ophthalmology and Vision Science, University of California, Sacramento, California, USA
Ophthalmology 115:1550-6, 1556.e1. 2008.... - Racial differences in optic disc topography: baseline results from the confocal scanning laser ophthalmoscopy ancillary study to the ocular hypertension treatment studyLinda M Zangwill
Department of Ophthalmology, University of California, San Diego, La Jolla 92093, USA
Arch Ophthalmol 122:22-8. 2004..To examine racial differences in optic disc topography among ocular hypertensive participants in the Ocular Hypertension Treatment Study... - Topical ocular hypotensive medication and lens opacification: evidence from the ocular hypertension treatment studyDavid C Herman
Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Am J Ophthalmol 142:800-10. 2006..We found no evidence for a general effect of topical ocular hypotensive medication on lens opacification or visual function... - Detection and prognostic significance of optic disc hemorrhages during the Ocular Hypertension Treatment StudyDonald L Budenz
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Ophthalmology 113:2137-43. 2006.... - The association between glaucomatous visual fields and optic nerve head features in the Ocular Hypertension Treatment StudyJohn L Keltner
Department of Ophthalmology and Visual Science, University of California, Davis, Sacramento, California 95817, USA
Ophthalmology 113:1603-12. 2006..To determine the association between change from baseline in the optic nerve head (ONH) and the visual field (VF) during follow-up of ocular hypertension participants in the Ocular Hypertension Treatment Study... - Baseline visual field characteristics in the ocular hypertension treatment studyChris A Johnson
Discoveries in Sight, Devers Eye Institute, Portland, Oregon
Ophthalmology 109:432-7. 2002..A clinical screening review of otherwise normal and reliable tests was not restrictive. The adoption of a 33% fixation loss cutoff significantly reduced the number of required retests and prevented study rejection of 89 patients... - Classification of visual field abnormalities in the ocular hypertension treatment studyJohn L Keltner
Visual Field Reading Center, Department of Ophthalmology, University of California Davis, Sacramento, 95817, USA
Arch Ophthalmol 121:643-50. 2003..1) To develop a classification system for visual field (VF) abnormalities, (2) to determine interreader and test-retest agreement, and (3) to determine the frequency of various VF defects in the Ocular Hypertension Treatment Study... - The confocal scanning laser ophthalmoscopy ancillary study to the ocular hypertension treatment study: study design and baseline factorsLinda M Zangwill
Department of Ophthalmology, University of California at San Diego, La Jolla, California 92093 0946, USA
Am J Ophthalmol 137:219-27. 2004.... - Variables affecting rigid contact lens comfort in the collaborative longitudinal evaluation of keratoconus (CLEK) studyTimothy B Edrington
Optom Vis Sci 81:182-8. 2004..To identify factors associated with rigid contact lens comfort in keratoconus... - The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individualsEve J Higginbotham
Department of Ophthalmology, Maryland Center for Eye Care Associates, Baltimore, USA
Arch Ophthalmol 122:813-20. 2004..50; 95% confidence interval, 0.28-0.90; P =.02). CONCLUSION: Topical ocular hypotensive therapy is effective in delaying or preventing the onset of POAG in African American individuals who have ocular hypertension... - Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment StudyAnne L Coleman
Jules Stein Eye Institute, University of California, Los Angeles, USA
Am J Ophthalmol 138:684-5. 2004..CONCLUSION: Whether PSD or VC/D was included in the Cox proportional hazards model, the same baseline factors were statistically significant and their hazard ratios were essentially similar... - Central corneal thickness and measured IOP response to topical ocular hypotensive medication in the Ocular Hypertension Treatment StudyJames D Brandt
Department of Ophthalmology, University of California, Davis, Sacramento, California, USA
Am J Ophthalmol 138:717-22. 2004..We believe that CCT measurements may be useful in patient management and in interpreting clinical trials of ocular hypotensive medication... - Incorporating the results of the Ocular Hypertension Treatment Study into clinical practiceMichael A Kass
Arch Ophthalmol 123:1021-2. 2005 - The Ocular Hypertension Treatment Study: reproducibility of cup/disk ratio measurements over time at an optic disc reading centerWilliam J Feuer
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA
Am J Ophthalmol 133:19-28. 2002..Horizontal cup/disk ratio measurements in OHTS are sufficiently reproducible to provide information about the relationship of cup/disk ratio to the prognosis of individuals with ocular hypertension... - Baseline topographic optic disc measurements are associated with the development of primary open-angle glaucoma: the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment StudyLinda M Zangwill
Hamilton Glaucoma Center and Diagnostic Imaging Laboratory, Department of Ophthalmology, University of California San Diego, La Jolla, CA 92093, USA
Arch Ophthalmol 123:1188-97. 2005..To determine whether baseline confocal scanning laser ophthalmoscopy (CSLO) optic disc topographic measurements are associated with the development of primary open-angle glaucoma (POAG) in individuals with ocular hypertension... - Normal visual field test results following glaucomatous visual field end points in the Ocular Hypertension Treatment StudyJohn L Keltner
Visual Field Reading Center, Department of Ophthalmology, University of California Davis, 4860 Y Street, Ste 2400, Sacramento, CA 95817, USA
Arch Ophthalmol 123:1201-6. 2005..To compare the occurrence of normal visual field (VF) test results following 2 vs 3 consecutive, abnormal, reliable test results in the Ocular Hypertension Treatment Study... - Test-retest reproducibility of optic disk deterioration detected from stereophotographs by masked gradersRichard K Parrish
Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, Florida, USA
Am J Ophthalmol 140:762-4. 2005..Consistency (specificity) in re-grading optic disks that did not develop deterioration was particularly high. The sensitivity results show that detecting subtle deterioration of optic disks is challenging... - Comparison of flat and steep rigid contact lens fitting methods in keratoconusKarla Zadnik
The Ohio State University College of Optometry, Columbus, 43210, USA
Optom Vis Sci 82:1014-21. 2005..The purpose of this article is to compare the safety and efficacy of flat- and steep-fitting rigid contact lenses in keratoconus... - Longitudinal changes in visual acuity in keratoconusLarry J Davis
University of Missouri-St. Louis College of Optometry, St. Louis, Missouri, USA
Invest Ophthalmol Vis Sci 47:489-500. 2006..Better baseline BCVA, steeper FDACL, and fundus abnormalities were predictive of greater acuity loss with time... - Differences in keratoconus as a function of genderBarbara A Fink
The Ohio State University College of Optometry, 338 West Tenth Avenue, Columbus OH 43210-1240, USA
Am J Ophthalmol 140:459-68. 2005..NEI-VFQ results revealed differences in self-reported difficulty with distance activities and driving. CONCLUSIONS: Gender differences exist in patient history, vision, and ocular symptoms in keratoconus patients... - Is a history of diabetes mellitus protective against developing primary open-angle glaucoma?Mae O Gordon
Arch Ophthalmol 126:280-1. 2008 - Estimation of the incidence and factors predictive of corneal scarring in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) StudyJoseph T Barr
Ohio State University College of Optometry, 338 West Tenth Avenue, Columbus, 43210-1240, USA
Cornea 25:16-25. 2006..These findings suggest a causal contribution of contact lens wear to corneal scarring in keratoconus and imply that corneal scarring might be reduced by modifying the contact lens fit... - Diabetes and glaucomaMichael A Kass
Arch Ophthalmol 126:746-7. 2008
Research Grants
- EGPS/OHTS Collaborative AnalysisMAE GORDON; Fiscal Year: 2005..A Joint Committee will be responsible for implementing the study, overseeing the analyses and preparing presentations and publications. ..
- CLEK-COORDINATING CENTERMAE GORDON; Fiscal Year: 2004..The DCC is responsible for the study design, management of study data, monitoring the performance of the Reading Center and participating clinics, preparation of performance reports, analysis of data and presentation of results. ..
- Ocular Hypertension Treatment Study: Coordinating CenterMAE GORDON; Fiscal Year: 2007..Developing plans for the orderly close-out of the study including participants, clinics, and resource centers 9. Archiving and documenting study data. ..