JEFFREY IVAN GORDON

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. doi request reprint The human gut microbiota and undernutrition
    Jeffrey I Gordon
    Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
    Sci Transl Med 4:137ps12. 2012
  2. pmc Moving pictures of the human microbiome
    J Gregory Caporaso
    Department of Chemistry and Biochemistry, University of Colorado, 215 UCB, Boulder, CO 80309, USA
    Genome Biol 12:R50. 2011
  3. doi request reprint Honor thy gut symbionts redux
    Jeffrey I Gordon
    Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
    Science 336:1251-3. 2012
  4. pmc Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure
    Amanda L Lewis
    Glycobiology Research and Training Center, Departments of Pediatrics, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 106:13552-7. 2009
  5. pmc Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation
    Peter A Crawford
    Center for Genome Sciences and Department of Medicine, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 106:11276-81. 2009
  6. ncbi request reprint A genomic view of our symbiosis with members of the gut microbiota
    Jeffrey I Gordon
    Center for Genome Sciences and Department of Molecular Biology and Pharmacology, Washington University, St Louis, Missouri, USA
    J Pediatr Gastroenterol Nutr 40:S28. 2005
  7. ncbi request reprint MapLinker: a software tool that aids physical map-linked whole genome shotgun assembly
    Jian Xu
    Center for Genome Sciences and Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63108, USA
    Bioinformatics 21:1265-6. 2005
  8. ncbi request reprint Response from Jeffrey I. Gordon et al.: Commensal bacteria make a difference
    Jeffrey I Gordon
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63110, USA
    Trends Microbiol 11:150-1. 2003
  9. ncbi request reprint How host-microbial interactions shape the nutrient environment of the mammalian intestine
    Lora V Hooper
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Nutr 22:283-307. 2002
  10. ncbi request reprint Improved magnetic resonance imaging detection of prostate cancer in a transgenic mouse model
    Sheng Kwei Song
    Biomedical MR Laboratory, Department of Chemistry, Washington University, St Louis, Missouri 63110, USA
    Cancer Res 62:1555-8. 2002

Collaborators

Detail Information

Publications11

  1. doi request reprint The human gut microbiota and undernutrition
    Jeffrey I Gordon
    Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
    Sci Transl Med 4:137ps12. 2012
    ..This effort will require elucidation of the interrelationships between breast milk composition and the development of the microbiota and immune system in the context of the maternal-infant dyad...
  2. pmc Moving pictures of the human microbiome
    J Gregory Caporaso
    Department of Chemistry and Biochemistry, University of Colorado, 215 UCB, Boulder, CO 80309, USA
    Genome Biol 12:R50. 2011
    ..Here, we present the largest human microbiota time series analysis to date, covering two individuals at four body sites over 396 timepoints...
  3. doi request reprint Honor thy gut symbionts redux
    Jeffrey I Gordon
    Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
    Science 336:1251-3. 2012
    ..It is captivating to the public and carries substantial expectations. As such, participating scientists need to sponsor proactive, solution-focused discussions of its societal implications...
  4. pmc Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure
    Amanda L Lewis
    Glycobiology Research and Training Center, Departments of Pediatrics, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 106:13552-7. 2009
    ..Together, these data indicate that some of the long-standing paradigms in Sia biology should be reconsidered in a wider evolutionary context of the extended family of NulO sugars...
  5. pmc Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation
    Peter A Crawford
    Center for Genome Sciences and Department of Medicine, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 106:11276-81. 2009
    ..Together, these results illustrate benefits provided by the gut microbiota during periods of nutrient deprivation, and emphasize the importance of further exploring the relationship between gut microbes and cardiovascular health...
  6. ncbi request reprint A genomic view of our symbiosis with members of the gut microbiota
    Jeffrey I Gordon
    Center for Genome Sciences and Department of Molecular Biology and Pharmacology, Washington University, St Louis, Missouri, USA
    J Pediatr Gastroenterol Nutr 40:S28. 2005
  7. ncbi request reprint MapLinker: a software tool that aids physical map-linked whole genome shotgun assembly
    Jian Xu
    Center for Genome Sciences and Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63108, USA
    Bioinformatics 21:1265-6. 2005
    ..Using the locations of sequence markers on the physical map, MapLinker generates a tentative sequence map of the genome that serves to verify the map and to guide genome-wide finishing...
  8. ncbi request reprint Response from Jeffrey I. Gordon et al.: Commensal bacteria make a difference
    Jeffrey I Gordon
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63110, USA
    Trends Microbiol 11:150-1. 2003
    ....
  9. ncbi request reprint How host-microbial interactions shape the nutrient environment of the mammalian intestine
    Lora V Hooper
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Nutr 22:283-307. 2002
    ..These and other studies underscore the importance of understanding precisely how nutrient metabolism serves to establish and sustain symbiotic relationships between mammals and their bacterial partners...
  10. ncbi request reprint Improved magnetic resonance imaging detection of prostate cancer in a transgenic mouse model
    Sheng Kwei Song
    Biomedical MR Laboratory, Department of Chemistry, Washington University, St Louis, Missouri 63110, USA
    Cancer Res 62:1555-8. 2002
    ..00001). Clinical application of DWI may offer advantages over current T2-weighted magnetic resonance imaging methods...
  11. ncbi request reprint Genetic mosaic analysis indicates that the bulb region of coat hair follicles contains a resident population of several active multipotent epithelial lineage progenitors
    Raphael Kopan
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Dev Biol 242:44-57. 2002
    ..This latter feature resembles the behavior of hematopoietic stem cells after bone marrow transplantation, and raises the question of whether this property may be shared by stem cells in other self-renewing epithelia...

Research Grants45

  1. GUT MICROBIOTA AND OBESITY: STUDIES IN GNOTOBIOTIC MICE
    JEFFREY IVAN GORDON; Fiscal Year: 2010
    ....
  2. REGULATION OF GENE EXPRESSION IN THE SMALL INTESTINE
    Jeffrey Gordon; Fiscal Year: 2005
    ..abstract_text> ..
  3. GNOTOBIOTIC TRANSGENIC MODELS OF THE GASTRIC ECOSYSTEM
    Jeffrey Gordon; Fiscal Year: 2005
    ..These studies should yield new insights about H. pylori pathogenesis plus markers for identifying patients at risk for severe pathology. ..
  4. Gastric and intestinal epithelial progenitor cell GAP
    Jeffrey Gordon; Fiscal Year: 2004
    ..3) In situ hybridization studies of the adult mouse and human gut will be used to obtain a more refined view of the cellular basis of expression of genes selected from (1) and (2). ..
  5. 4th International Conference on Systems Biology
    Jeffrey Gordon; Fiscal Year: 2004
    ....
  6. PROTEIN MYRISTOYLATION IN S CEREVISIAE AND C NEOFORMANS
    Jeffrey Gordon; Fiscal Year: 2004
    ..They should also provide molecular insights about the relationship between resistance to nutrient deprivation and aging that are applicable to other organisms. ..
  7. Genomic and metabolomic foundations of human-microbial symbiosis in the gut
    Jeffrey Gordon; Fiscal Year: 2007
    ..M. smithii, and E. rectale/E. eligens. These studies should provide new approaches for monitoring and manipulating the functions of the microbiota to promote human health. ..
  8. GNOTOBIOTIC TRANSGENIC MODELS OF THE GASTRIC ECOSYSTEM
    JEFFREY IVAN GORDON; Fiscal Year: 2010
    ..These analyses should provide the first genome-wide view of Hp evolution in ChAG and Ca, and yield new bacterial and host biomarkers associated with these states. ..
  9. GNOTOBIOTIC TRANSGENIC MODELS OF THE GASTRIC ECOSYSTEM
    Jeffrey Gordon; Fiscal Year: 2009
    ..These analyses should provide the first genome-wide view of Hp evolution in ChAG and Ca, and yield new bacterial and host biomarkers associated with these states. ..
  10. Gut microbiota and obesity: studies in gnotobiotic mice
    Jeffrey Gordon; Fiscal Year: 2009
    ..abstract_text> ..
  11. GNOTOBIOTIC TRANSGENIC MODELS OF THE GASTRIC ECOSYSTEM
    Jeffrey Gordon; Fiscal Year: 2007
    ..These analyses should provide the first genome-wide view of Hp evolution in ChAG and Ca, and yield new bacterial and host biomarkers associated with these states. ..
  12. Gut microbiota and obesity: studies in gnotobiotic mice
    Jeffrey Gordon; Fiscal Year: 2007
    ..abstract_text> ..
  13. REGULATION OF GENE EXPRESSION - SMALL INTESTINE
    Jeffrey Gordon; Fiscal Year: 1992
    ....
  14. TRANSGENIC MOUSE MODELS FOR STUDYING PROSTATE/GU DISEASE
    Jeffrey Gordon; Fiscal Year: 2002
    ..These mice will allow future tests of the contributions of various genes to urothelial function in health and disease. ..