B Geller

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Prepubertal and early adolescent bipolarity differentiate from ADHD by manic symptoms, grandiose delusions, ultra-rapid or ultradian cycling
    B Geller
    Washington University School of Medicine, St Louis, MO, 63110, USA
    J Affect Disord 51:81-91. 1998
  2. ncbi Phenomenology of prepubertal and early adolescent bipolar disorder: examples of elated mood, grandiose behaviors, decreased need for sleep, racing thoughts and hypersexuality
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 12:3-9. 2002
  3. ncbi Two-year prospective follow-up of children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Psychiatry 159:927-33. 2002
  4. ncbi GAD1 single nucleotide polymorphism is in linkage disequilibrium with a child bipolar I disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Child Adolesc Psychopharmacol 18:25-9. 2008
  5. ncbi Proposed definitions of bipolar I disorder episodes and daily rapid cycling phenomena in preschoolers, school-aged children, adolescents, and adults
    Barbara Geller
    Washington University School of Medicine, Department of Psychiatry, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 17:217-22. 2007
  6. ncbi Four-year prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, MO 63110, USA
    Arch Gen Psychiatry 61:459-67. 2004
  7. ncbi Controlled, blindly rated, direct-interview family study of a prepubertal and early-adolescent bipolar I disorder phenotype: morbid risk, age at onset, and comorbidity
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, St Louis, MO 63110 1093, USA
    Arch Gen Psychiatry 63:1130-8. 2006
  8. ncbi Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 161:1698-700. 2004
  9. ncbi Are the arginine vasopressin V1a receptor microsatellites related to hypersexuality in children with a prepubertal and early adolescent bipolar disorder phenotype?
    Barbara Geller
    Washington University School of Medicine, St Louis, MO 63110, USA
    Bipolar Disord 7:610-6. 2005
  10. ncbi DSM-IV mania symptoms in a prepubertal and early adolescent bipolar disorder phenotype compared to attention-deficit hyperactive and normal controls
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 12:11-25. 2002

Research Grants

  1. Treatment of Early Age Mania (TEAM)
    Barbara Geller; Fiscal Year: 2007

Detail Information

Publications40

  1. ncbi Prepubertal and early adolescent bipolarity differentiate from ADHD by manic symptoms, grandiose delusions, ultra-rapid or ultradian cycling
    B Geller
    Washington University School of Medicine, St Louis, MO, 63110, USA
    J Affect Disord 51:81-91. 1998
    ..To address this ddx issue, and to provide prepubertal mania manifestations, interim baseline data are presented from the National Institute of Mental Health (NIMH)-funded study 'Phenomenology and Course of Pediatric Bipolarity'...
  2. ncbi Phenomenology of prepubertal and early adolescent bipolar disorder: examples of elated mood, grandiose behaviors, decreased need for sleep, racing thoughts and hypersexuality
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 12:3-9. 2002
    ..g., children do not "max" out credit cards or have four marriages). To address this issue, our group investigated prepubertal and early adolescent age equivalents of adult mania behaviors...
  3. ncbi Two-year prospective follow-up of children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Psychiatry 159:927-33. 2002
    ..This study sought to provide rates and predictors of recovery and relapse in children with a prepubertal and early adolescent bipolar disorder phenotype...
  4. ncbi GAD1 single nucleotide polymorphism is in linkage disequilibrium with a child bipolar I disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Child Adolesc Psychopharmacol 18:25-9. 2008
    ..Thus, it is of interest to examine the association of GAD1 to child BP-I because of its recently reported association to childhood SZ...
  5. ncbi Proposed definitions of bipolar I disorder episodes and daily rapid cycling phenomena in preschoolers, school-aged children, adolescents, and adults
    Barbara Geller
    Washington University School of Medicine, Department of Psychiatry, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 17:217-22. 2007
    ..These data may reflect actual sample differences, but the absence of uniformly applied definitions of episode duration, number of lifetime episodes and daily rapid cycling patterns during episodes may also account for these differences...
  6. ncbi Four-year prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, MO 63110, USA
    Arch Gen Psychiatry 61:459-67. 2004
    ..Diagnosis of child mania has been contentious...
  7. ncbi Controlled, blindly rated, direct-interview family study of a prepubertal and early-adolescent bipolar I disorder phenotype: morbid risk, age at onset, and comorbidity
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, St Louis, MO 63110 1093, USA
    Arch Gen Psychiatry 63:1130-8. 2006
    ..This question arises because of the greater severity, longer current episode duration, preponderance of mania, and high rates of ultradian rapid cycling and comorbid attention-deficit/hyperactivity disorder (ADHD) in PEA-BP-I...
  8. ncbi Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 161:1698-700. 2004
    ..Transmission of the brain-derived neurotrophic factor (BDNF) Val66 allele in children with a prepubertal and early adolescent bipolar disorder phenotype was examined...
  9. ncbi Are the arginine vasopressin V1a receptor microsatellites related to hypersexuality in children with a prepubertal and early adolescent bipolar disorder phenotype?
    Barbara Geller
    Washington University School of Medicine, St Louis, MO 63110, USA
    Bipolar Disord 7:610-6. 2005
    ..Preferential transmission of the number of AVPR1A microsatellite repeats to hypersexual and uninhibited people-seeking probands was hypothesized, based on reports from preclinical work in the literature...
  10. ncbi DSM-IV mania symptoms in a prepubertal and early adolescent bipolar disorder phenotype compared to attention-deficit hyperactive and normal controls
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 12:11-25. 2002
    ....
  11. ncbi Prepubertal and early adolescent bipolar I disorder: review of diagnostic validation by Robins and Guze criteria
    Barbara Geller
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA
    J Clin Psychiatry 66:21-8. 2005
    ..Continuities between PEA-BP and adult bipolar disorder and relationships of PEA-BP to other descriptions of child mania are discussed...
  12. ncbi Psychosocial functioning in a prepubertal and early adolescent bipolar disorder phenotype
    B Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis 63110, USA
    J Am Acad Child Adolesc Psychiatry 39:1543-8. 2000
    ..To compare psychosocial functioning (PF) in a prepubertal and early adolescent bipolar disorder phenotype (PEA-BP) sample to two comparison groups, i.e., attention-deficit/hyperactivity disorder (ADHD) and community controls (CC)...
  13. ncbi Diagnostic characteristics of 93 cases of a prepubertal and early adolescent bipolar disorder phenotype by gender, puberty and comorbid attention deficit hyperactivity disorder
    B Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 10:157-64. 2000
    ....
  14. ncbi Six-month stability and outcome of a prepubertal and early adolescent bipolar disorder phenotype
    B Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 10:165-73. 2000
    ..Six-month follow-up data are provided on a prepubertal and early adolescent bipolar disorder phenotype (PEA-BP). Stabilities were defined as continuous presence of PEA-BP and of individual mania criteria between baseline and 6 months...
  15. ncbi Bipolar disorder at prospective follow-up of adults who had prepubertal major depressive disorder
    B Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Psychiatry 158:125-7. 2001
    ..The authors' goal was to conduct an adult follow-up of subjects who had participated in a study of nortriptyline for childhood depression...
  16. ncbi One-year recovery and relapse rates of children with a prepubertal and early adolescent bipolar disorder phenotype
    B Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Psychiatry 158:303-5. 2001
    ..The study examined 1-year recovery and relapse rates for mania in subjects who met criteria for a prepubertal and early adolescent bipolar disorder phenotype...
  17. ncbi Reliability of the Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) mania and rapid cycling sections
    B Geller
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 40:450-5. 2001
    ..To investigate the reliability of the Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) mania and rapid cycling sections...
  18. ncbi Adult psychosocial outcome of prepubertal major depressive disorder
    B Geller
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 40:673-7. 2001
    ..To compare adult psychosocial functioning (PSF) of subjects with prepubertal major depressive disorder (PMDD) to a normal comparison (NC) group...
  19. ncbi Prepubertal and young adolescent bipolarity versus ADHD: assessment and validity using the WASH-U-KSADS, CBCL and TRF
    B Geller
    Washington University School of Medicine, St Louis, MO, 63110, USA
    J Affect Disord 51:93-100. 1998
    ....
  20. ncbi Lithium for prepubertal depressed children with family history predictors of future bipolarity: a double-blind, placebo-controlled study
    B Geller
    Washington University School of Medicine, St Louis, MO 63110, USA
    J Affect Disord 51:165-75. 1998
    ....
  21. ncbi Relationship of parent and child informants to prevalence of mania symptoms in children with a prepubertal and early adolescent bipolar disorder phenotype
    Rebecca Tillman
    Department of Psychiatry, School of Medicine, Washington University St. Louis, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Am J Psychiatry 161:1278-84. 2004
    ..Differences in mania symptom profiles between investigative groups may be, in part, due to whether child informants were assessed...
  22. ncbi A brief screening tool for a prepubertal and early adolescent bipolar disorder phenotype
    Rebecca Tillman
    Department of Psychiatry, Washington University, St. Louis, MO 63110, USA
    Am J Psychiatry 162:1214-6. 2005
    ....
  23. ncbi Ages of onset and rates of syndromal and subsyndromal comorbid DSM-IV diagnoses in a prepubertal and early adolescent bipolar disorder phenotype
    Rebecca Tillman
    Department of Psychiatry, Washington University School of Medicine, St. Louis, USA
    J Am Acad Child Adolesc Psychiatry 42:1486-93. 2003
    ..Comparison with other studies demonstrated the importance of DSM system and severity scales in reporting comorbidity rates...
  24. ncbi Life events in a prepubertal and early adolescent bipolar disorder phenotype compared to attention-deficit hyperactive and normal controls
    Rebecca Tillman
    Washington University, St. Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 13:243-51. 2003
    ....
  25. ncbi A prepubertal and early adolescent bipolar disorder-I phenotype: review of phenomenology and longitudinal course
    James L Craney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Bipolar Disord 5:243-56. 2003
    ..CONCLUSION: Counterintuitively, typical 7-year-old children with PEA-BP were more severely ill than typical 27 year olds with adult-onset mania. Moreover, longitudinal data strongly supported differentiation of PEA-BP from ADHD...
  26. ncbi Controlled study of switching from attention-deficit/hyperactivity disorder to a prepubertal and early adolescent bipolar I disorder phenotype during 6-year prospective follow-up: rate, risk, and predictors
    Rebecca Tillman
    Department of Psychiatry, Washington University, St Louis, MO 63110 1093, USA
    Dev Psychopathol 18:1037-53. 2006
    ..BP I in first-degree relatives, antidepressants, psychosocial measures, and life events were not predictive...
  27. ncbi Child bipolar I disorder: prospective continuity with adult bipolar I disorder; characteristics of second and third episodes; predictors of 8-year outcome
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, 660 S Euclid Ave, St Louis, MO 63110 1093, USA
    Arch Gen Psychiatry 65:1125-33. 2008
    ..Child bipolar I disorder (BP-I) is a contentious diagnosis...
  28. ncbi Effects of age, sex, and independent life events on amygdala and nucleus accumbens volumes in child bipolar I disorder
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, St Louis, Missouri 63110 1093, USA
    Biol Psychiatry 65:432-7. 2009
    ..Relationships between environment and cortical-limbic-striatal pathways are not well-researched in child bipolar I disorder (BP-I)...
  29. ncbi Pharmacological and non-drug treatment of child bipolar I disorder during prospective eight-year follow-up
    Barbara Geller
    Department of Psychiatry, Washington University in St Louis, St Louis, MO 63110 1093, USA
    Bipolar Disord 12:164-71. 2010
    ....
  30. ncbi Temperament and character factors in a prepubertal and early adolescent bipolar disorder phenotype compared to attention deficit hyperactive and normal controls
    Rebecca Tillman
    Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 13:531-43. 2003
    ..CONCLUSION: These findings are consistent with studies of novelty seeking in adults who had either BP or ADHD and are discussed in relationship to genetic studies of dopamine receptors and novelty seeking...
  31. ncbi Controlled study of encopresis and enuresis in children with a prepubertal and early adolescent bipolar-I disorder phenotype
    Tricia Klages
    Department of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 44:1050-7. 2005
    ..7% versus 55.6%, chi2 = 8.3, p = .004). Parent-child concordance on reporting encopresis and enuresis was poor to fair. CONCLUSIONS: Children with PEA-BP need to be evaluated for encopresis, enuresis, and mother-child relationships...
  32. ncbi Children with a prepubertal and early adolescent bipolar disorder phenotype from pediatric versus psychiatric facilities
    Rebecca Tillman
    Department of Psychiatry, Washington University, St. Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 44:776-81. 2005
    ..Moreover, pediatricians may be more likely to refer children to psychiatrists when depression or suicidality is evident...
  33. ncbi Diagnostic characteristics of child bipolar I disorder: does the "Treatment of Early Age Mania (team)" sample generalize?
    Rebecca Tillman
    Department of Psychiatry, Washington University in St Louis, St Louis, MO 63110, USA
    J Clin Psychiatry 68:307-14. 2007
    ..To examine the representativeness of a randomized controlled trial (RCT) sample versus one obtained by consecutive new case ascertainment, for subjects with child bipolar I disorder...
  34. ncbi Psychotic phenomena in 257 young children and adolescents with bipolar I disorder: delusions and hallucinations (benign and pathological)
    Rebecca Tillman
    Department of Psychiatry, Washington University in St Louis, St Louis, MO 63110, USA
    Bipolar Disord 10:45-55. 2008
    ..In contrast to studies of adult bipolar I disorder (BP-I), there is a paucity of data on psychotic phenomena in child BP-I. Therefore, the aim of this work was to describe delusions and hallucinations in pediatric BP-I...
  35. ncbi Clinical implications of antidepressant and stimulant use on switching from depression to mania in children
    James Craney
    Washington University, St. Louis, Missouri, USA
    J Child Adolesc Psychopharmacol 13:201-4. 2003
  36. ncbi Definitions of rapid, ultrarapid, and ultradian cycling and of episode duration in pediatric and adult bipolar disorders: a proposal to distinguish episodes from cycles
    Rebecca Tillman
    Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Child Adolesc Psychopharmacol 13:267-71. 2003
    ..2) Cycles will be defined by mood switches occurring daily or every few days during an episode. Further research will be needed to elucidate potential differences between child and adult cycling patterns...
  37. ncbi Review of studies of child and adolescent offspring of bipolar parents
    M P Delbello
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Bipolar Disord 3:325-34. 2001
    ..The authors reviewed studies of child and adolescent offspring of bipolar (BP) parents. Findings from these studies are critically discussed with respect to methodological issues that can inform future designs...
  38. ncbi Prepubertal bipolar I disorder and bipolar disorder NOS are separable from ADHD
    Robert M Post
    J Clin Psychiatry 65:898-902. 2004
  39. ncbi Adaptive strategies for treating childhood mania
    Ree Dawson
    Frontier Science Technology and Research Foundation, Boston, Massachusetts 02215, USA
    Biol Psychiatry 61:758-64. 2007
    ..Our exposition is developed in the specific clinical context of childhood mania to maximize accessibility of the ideas but applies more generally to other chronic mental and physical health disorders that are difficult to treat...
  40. ncbi National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders
    Dennis S Charney
    Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 59:262-70. 2002
    ..Research is needed on the ethical conduct of studies to limit risks of medication-free intervals and facilitate poststudy treatment. Patients must fully understand the risks and lack of individualized treatment involved in research...

Research Grants1

  1. Treatment of Early Age Mania (TEAM)
    Barbara Geller; Fiscal Year: 2007
    ..The chief study statistician, Dr. Satish lyengar is subcontracted to the coordinating site at Washington U in St. Louis and Dr. Philip Lavori is a major consultant for statistical analyses. ..