Richard Gelberman

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint The early effects of sustained platelet-derived growth factor administration on the functional and structural properties of repaired intrasynovial flexor tendons: an in vivo biomechanic study at 3 weeks in canines
    Richard H Gelberman
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, St Louis, MO 63110, USA
    J Hand Surg Am 32:373-9. 2007
  2. doi request reprint Osteochondroma of the capitate causing rupture of the extensor digiti minimi: case report
    Nirav R Shah
    Department of Orthopaedic Surgery, Washington University School of Medicine, Saint Louis, MO 63110, USA
    J Hand Surg Am 34:46-8. 2009
  3. ncbi request reprint Zone I flexor digitorum profundus repair: an ex vivo biomechanical analysis of tendon to bone repair in cadavera
    Thomas T Dovan
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, St Louis, MO, USA
    J Hand Surg Am 30:258-66. 2005
  4. ncbi request reprint Recent progress in flexor tendon healing. The modulation of tendon healing with rehabilitation variables
    Martin I Boyer
    Department of Orthopaedic Surgery, Orthopaedic Hand Surgery Service, Saint Louis, Missouri 63110, USA
    J Hand Ther 18:80-5; quiz 86. 2005
  5. ncbi request reprint Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro
    Stavros Thomopoulos
    Department of Orthopaedic Research, Washington University, St Louis, MO, USA
    J Hand Surg Am 30:441-7. 2005
  6. ncbi request reprint Early healing of flexor tendon insertion site injuries: Tunnel repair is mechanically and histologically inferior to surface repair in a canine model
    Matthew J Silva
    Department of Orthopaedic Surgery, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, Suite 11300 WP, St Louis, Missouri 63110, USA
    J Orthop Res 24:990-1000. 2006
  7. pmc The alchemy of tendon repair: a primer for the (S)mad scientist
    Dwight A Towler
    Department of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Clin Invest 116:863-6. 2006
  8. ncbi request reprint Alendronate prevents bone loss and improves tendon-to-bone repair strength in a canine model
    Stavros Thomopoulos
    Department of Orthopaedic Surgery, Washington University, 1 Barnes Jewish Hospital Plaza, Suite 11300, Campus Box 8233, St Louis, Missouri 63110, USA
    J Orthop Res 25:473-9. 2007
  9. ncbi request reprint PDGF-BB released in tendon repair using a novel delivery system promotes cell proliferation and collagen remodeling
    Stavros Thomopoulos
    Department of Orthopaedics, Washington University, St Louis, Missouri 63110, USA
    J Orthop Res 25:1358-68. 2007
  10. doi request reprint Effect of suture material and bone quality on the mechanical properties of zone I flexor tendon-bone reattachment with bone anchors
    Hironori Matsuzaki
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Hand Surg Am 33:709-17. 2008

Research Grants

  1. FLEXOR TENDON HEALING
    Richard Gelberman; Fiscal Year: 2007
  2. FLEXOR TENDON HEALING
    Richard Gelberman; Fiscal Year: 2004
  3. FLEXOR TENDON HEALING
    Richard Gelberman; Fiscal Year: 1999
  4. FLEXOR TENDON HEALING
    Richard H Gelberman; Fiscal Year: 2010

Collaborators

Detail Information

Publications27

  1. ncbi request reprint The early effects of sustained platelet-derived growth factor administration on the functional and structural properties of repaired intrasynovial flexor tendons: an in vivo biomechanic study at 3 weeks in canines
    Richard H Gelberman
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, St Louis, MO 63110, USA
    J Hand Surg Am 32:373-9. 2007
    ..We hypothesized that PDGF-BB administered in this manner would improve the sutured tendon's functional and structural properties 3 weeks after repair...
  2. doi request reprint Osteochondroma of the capitate causing rupture of the extensor digiti minimi: case report
    Nirav R Shah
    Department of Orthopaedic Surgery, Washington University School of Medicine, Saint Louis, MO 63110, USA
    J Hand Surg Am 34:46-8. 2009
    ..Attritional rupture of the extensor digiti minimi tendon resulted from mechanical irritation as it coursed over the mass. Surgical excision of the mass with tendon transfer of the extensor digiti minimi was subsequently performed...
  3. ncbi request reprint Zone I flexor digitorum profundus repair: an ex vivo biomechanical analysis of tendon to bone repair in cadavera
    Thomas T Dovan
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, St Louis, MO, USA
    J Hand Surg Am 30:258-66. 2005
    ..The purpose of this study was to evaluate the ex vivo biomechanical properties of 2 new repair techniques in comparison with the standard FDP tendon to distal phalanx cortical surface repair...
  4. ncbi request reprint Recent progress in flexor tendon healing. The modulation of tendon healing with rehabilitation variables
    Martin I Boyer
    Department of Orthopaedic Surgery, Orthopaedic Hand Surgery Service, Saint Louis, Missouri 63110, USA
    J Hand Ther 18:80-5; quiz 86. 2005
    ....
  5. ncbi request reprint Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro
    Stavros Thomopoulos
    Department of Orthopaedic Research, Washington University, St Louis, MO, USA
    J Hand Surg Am 30:441-7. 2005
    ..Our second hypothesis was that there would be a positive effect from the combination of PDGF-BB and bFGF...
  6. ncbi request reprint Early healing of flexor tendon insertion site injuries: Tunnel repair is mechanically and histologically inferior to surface repair in a canine model
    Matthew J Silva
    Department of Orthopaedic Surgery, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, Suite 11300 WP, St Louis, Missouri 63110, USA
    J Orthop Res 24:990-1000. 2006
    ..If the results of our animal study extend to healing of the human FDP insertion, they indicate that FDP tendons should be reattached to the distal phalanx by suture to the cortical surface rather than suture in a bone tunnel...
  7. pmc The alchemy of tendon repair: a primer for the (S)mad scientist
    Dwight A Towler
    Department of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Clin Invest 116:863-6. 2006
    ..g., osteoblasts, myocytes, chondrocytes, and tenocytes--that may be useful in cell-based therapeutic approaches to musculoskeletal diseases...
  8. ncbi request reprint Alendronate prevents bone loss and improves tendon-to-bone repair strength in a canine model
    Stavros Thomopoulos
    Department of Orthopaedic Surgery, Washington University, 1 Barnes Jewish Hospital Plaza, Suite 11300, Campus Box 8233, St Louis, Missouri 63110, USA
    J Orthop Res 25:473-9. 2007
    ..These initial short-term data demonstrate the potential for a clinical treatment that could enhance tendon-to-bone healing...
  9. ncbi request reprint PDGF-BB released in tendon repair using a novel delivery system promotes cell proliferation and collagen remodeling
    Stavros Thomopoulos
    Department of Orthopaedics, Washington University, St Louis, Missouri 63110, USA
    J Orthop Res 25:1358-68. 2007
    ..Sustained delivery of growth factors may be achieved using a novel fibrin-based delivery system. PDGF-BB delivery increased cell proliferation and matrix remodeling and thus may accelerate flexor tendon healing...
  10. doi request reprint Effect of suture material and bone quality on the mechanical properties of zone I flexor tendon-bone reattachment with bone anchors
    Hironori Matsuzaki
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Hand Surg Am 33:709-17. 2008
    ..To compare the initial biomechanical properties of zone I flexor tendon to bone repairs performed using pull-out and anchor techniques and to investigate the effect of bone quality and suture materials on the strength of anchor repairs...
  11. doi request reprint Ganglia of the hand and wrist: a sonographic analysis
    Sharlene A Teefey
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110, USA
    AJR Am J Roentgenol 191:716-20. 2008
    ..The purpose of this study was to analyze the sonographic appearance of a large series of pathologically proven ganglia...
  12. ncbi request reprint Flexor digitorum profundus tendon to bone tunnel repair: a vascularization and histologic study in canines
    Thomas T Dovan
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, St Louis, MO, USA
    J Hand Surg Am 30:246-57. 2005
    ..The purpose of this study was to analyze the histologic and vascular anatomic properties of the FDP insertion site after transection and repair in a bone tunnel within the distal phalanx...
  13. ncbi request reprint The rigidity of repaired flexor tendons increases following ex vivo cyclic loading
    Konstantinos T Ditsios
    Department of Orthopaedic Surgery, Washington University, Suite 11300, 1 Barnes Jewish Plaza, St Louis, MO 63100, USA
    J Biomech 35:853-6. 2002
    ....
  14. ncbi request reprint The insertion site of the canine flexor digitorum profundus tendon heals slowly following injury and suture repair
    Matthew J Silva
    Department of Orthopaedic Surgery, Barnes Jewish Hospital, Washington University, St Louis, MO 63110, USA
    J Orthop Res 20:447-53. 2002
    ..While these findings may be limited to the particular repair method we used, they demonstrate a need for devising new treatment strategies to improve healing of flexor tendon insertion site injuries...
  15. ncbi request reprint Repair of flexor digitorum profundus tendon avulsions from bone: an ex vivo biomechanical analysis
    Martin I Boyer
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, One Barnes Jewish Hospital, Suite 11300 West Pavilion, St Louis, MO 63110, USA
    J Hand Surg Am 27:594-8. 2002
    ..Neither suture caliber nor repair technique had a notable effect on strain at 20-N force, suggesting that early gap formation at the tendon-bone repair site may occur regardless of technique...
  16. ncbi request reprint Recent progress in flexor tendon healing
    Matthew J Silva
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300 West Pavilion, St Louis, MO 63110, USA
    J Orthop Sci 7:508-14. 2002
    ..Future advances will probably require manipulation of the biological factors that promote healing...
  17. ncbi request reprint Neovascularization of the flexor digitorum profundus tendon after avulsion injury: an in vivo canine study
    Konstantinos Ditsios
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Hand Surg Am 28:231-6. 2003
    ..Our objective was to determine both the time course and the source of neovascularization of the tendon stump in an in vivo canine model of flexor digitorum profundus (FDP) avulsion after a clinically relevant delay in diagnosis...
  18. ncbi request reprint Two-portal repair of canine flexor tendon insertion site injuries: histologic and immunohistochemical characterization of healing during the early postoperative period
    Martin I Boyer
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63130, USA
    J Hand Surg Am 28:469-74. 2003
    ..The hypothesis was that the tendon-bone interface matures and assumes a progressively more anatomic histologic and immunohistochemical appearance during the first 6 weeks after repair...
  19. ncbi request reprint Bone loss following tendon laceration, repair and passive mobilization
    Konstantinos Ditsios
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, Suite 11300 WP, 1 Barnes Jewish Plaza, Saint Louis, MO 63110, USA
    J Orthop Res 21:990-6. 2003
    ..This bone loss may impact healing by impeding the restoration of a strong tendon-bone interface...
  20. ncbi request reprint Tendon injury response: assessment of biomechanical properties, tissue morphology and viability following flexor digitorum profundus tendon transection
    Matthew J Silva
    Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, 1 Barnes Jewish Plaza, Suite 1100 WP, St Louis, MO 63110, USA
    J Orthop Res 22:990-7. 2004
    ..This leads to increased tendon size and enhanced resistance to suture pullout. These findings offer a scientific rationale supporting the clinical practice of surgical re-attachment within the first 3 weeks after injury...
  21. ncbi request reprint Treatment of distal radius fractures with a low-profile dorsal plating system: an outcomes assessment
    Paul M Simic
    Southern California Orthopaedic Institute, Van Nuys, CA, USA
    J Hand Surg Am 31:382-6. 2006
    ..Our hypothesis was that the low-profile dorsal plating system would allow for a reduction of extensor tendon irritation and pain and provide stable osseous fixation...
  22. ncbi request reprint Vascular anatomy of the human flexor digitorum profundus tendon insertion
    Fraser J Leversedge
    Department of Orthopaedic Surgery, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, MO 63110, USA
    J Hand Surg Am 27:806-12. 2002
    ....
  23. ncbi request reprint Anatomic tilt x-rays of the distal radius: an ex vivo analysis of surgical fixation
    Martin I Boyer
    Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes Jewish Hospital, Suite 11300 West Pavilion, One Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
    J Hand Surg Am 29:116-22. 2004
    ..To compare anatomic tilt radiographs with standard posteroanterior (PA) and lateral radiographs for their efficacy in detecting screw penetration of the distal radius articular surface...
  24. ncbi request reprint Vascularity and osteonecrosis of the wrist
    Michael J Botte
    Division of Orthopaedic Surgery, Scripps Clinic, 10666 North Torrey Pines Road, La Jolla, CA 92037, USA
    Orthop Clin North Am 35:405-21, xi. 2004
    ..Separate discussions of etiology, diagnosis, and treatment of osteonecrosis of the commonly involved carpal bones are included...
  25. ncbi request reprint The radial nerve in the brachium: an anatomic study in human cadavers
    Douglas Carlan
    Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes Jewish Hospital, 1 Barnes Jewish Plaza, St Louis, MO 63110, USA
    J Hand Surg Am 32:1177-82. 2007
    ..To explore the course of the radial nerve in the brachium and to identify practical anatomic landmarks that can be used to avoid iatrogenic injury during humerus fracture fixation...
  26. ncbi request reprint Entrapment of the sciatic nerve by the femoral neck following closed reduction of a hip prosthesis : a case report
    Fraser J Leversedge
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 84:1210-3. 2002
  27. ncbi request reprint Nerve decompression for complex regional pain syndrome type II following upper extremity surgery
    Jeffrey D Placzek
    Department of Orthopaedic Surgery, Washington University, One Barnes Jewish Plaza, St Louis, MO 63110, USA
    J Hand Surg Am 30:69-74. 2005
    ..To evaluate the results of nerve decompression for the symptoms of complex regional pain syndrome that developed after upper-extremity surgery...

Research Grants14

  1. FLEXOR TENDON HEALING
    Richard Gelberman; Fiscal Year: 2007
    ..They will extend our understanding of the critical early stages of healing and will provide therapeutic solutions for the most prevalent clinical problems associated with tendon injury and repair. ..
  2. FLEXOR TENDON HEALING
    Richard Gelberman; Fiscal Year: 2004
    ..Identification of improved repair and rehabilitation techniques for insertion-site injuries will be an initial step toward modernizing clinical treatment and improving patient outcomes. ..
  3. FLEXOR TENDON HEALING
    Richard Gelberman; Fiscal Year: 1999
    ....
  4. FLEXOR TENDON HEALING
    Richard H Gelberman; Fiscal Year: 2010
    ..They will extend our understanding of the critical early stages of healing and will provide therapeutic solutions for the most prevalent clinical problems associated with tendon injury and repair. ..