J R Garbow

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint MRI measurement of liver regeneration in mice following partial hepatectomy
    J R Garbow
    Department of Chemistry, Washington University, St Louis, Missouri 63110, USA
    Magn Reson Med 52:177-80. 2004
  2. ncbi request reprint In vivo MRS measurement of liver lipid levels in mice
    J R Garbow
    Department of Chemistry and Alvin J Siteman Cancer Center, Washington University, St Louis, MO 63130, USA
    J Lipid Res 45:1364-71. 2004
  3. ncbi request reprint Detection of primary lung tumors in rodents by magnetic resonance imaging
    Joel R Garbow
    Department of Chemistry, Washington University, St Louis, Missouri, USA
    Cancer Res 64:2740-2. 2004
  4. pmc Magnetic resonance imaging defines cervicovaginal anatomy, cancer, and VEGF trap antiangiogenic efficacy in estrogen-treated K14-HPV16 transgenic mice
    Joel R Garbow
    Department of Radiology, Alvin J Siteman Cancer Center, Washington University in St Louis, Missouri 63110, USA
    Cancer Res 69:7945-52. 2009
  5. doi request reprint Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging
    Joel R Garbow
    Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Cancer Res 14:1363-7. 2008
  6. ncbi request reprint CXCR4 regulates growth of both primary and metastatic breast cancer
    Matthew C P Smith
    Molecular Imaging Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA
    Cancer Res 64:8604-12. 2004
  7. ncbi request reprint Structure, dynamics, and stability of beta-cyclodextrin inclusion complexes of aspartame and neotame
    J R Garbow
    Analytical Sciences Center, Pharmacia Corporation, 800 North Lindbergh Boulevard, St Louis, Missouri 63167, USA
    J Agric Food Chem 49:2053-60. 2001
  8. pmc Frequency-dependent viscoelastic parameters of mouse brain tissue estimated by MR elastography
    E H Clayton
    Department of Mechanical Engineering and Materials Science, Washington University in St Louis, 1 Brookings Drive, Campus Box 1185, Saint Louis, MO 63130, USA
    Phys Med Biol 56:2391-406. 2011
  9. pmc Orthotopic mouse lung transplantation as experimental methodology to study transplant and tumor biology
    Alexander S Krupnick
    Department of Surgery, Washington University School of Medicine, Campus Box 8234, 660 South Euclid Avenue, St Louis, Missouri 63110, USA
    Nat Protoc 4:86-93. 2009
  10. pmc Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases
    Beatriz M Carreno
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Cancer Res 15:3277-86. 2009

Collaborators

Detail Information

Publications37

  1. ncbi request reprint MRI measurement of liver regeneration in mice following partial hepatectomy
    J R Garbow
    Department of Chemistry, Washington University, St Louis, Missouri 63110, USA
    Magn Reson Med 52:177-80. 2004
    ..The success of this method will enable future studies to better elucidate the factors that affect regeneration, and help to optimize the timing and dosing of chemotherapeutics to minimize their deleterious effects on liver regeneration...
  2. ncbi request reprint In vivo MRS measurement of liver lipid levels in mice
    J R Garbow
    Department of Chemistry and Alvin J Siteman Cancer Center, Washington University, St Louis, MO 63130, USA
    J Lipid Res 45:1364-71. 2004
    ....
  3. ncbi request reprint Detection of primary lung tumors in rodents by magnetic resonance imaging
    Joel R Garbow
    Department of Chemistry, Washington University, St Louis, Missouri, USA
    Cancer Res 64:2740-2. 2004
    ....
  4. pmc Magnetic resonance imaging defines cervicovaginal anatomy, cancer, and VEGF trap antiangiogenic efficacy in estrogen-treated K14-HPV16 transgenic mice
    Joel R Garbow
    Department of Radiology, Alvin J Siteman Cancer Center, Washington University in St Louis, Missouri 63110, USA
    Cancer Res 69:7945-52. 2009
    ....
  5. doi request reprint Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging
    Joel R Garbow
    Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Cancer Res 14:1363-7. 2008
    ..The goal of this work was to monitor quantitatively the development and progression of adenocarcinoma in a time course study of mice treated with the carcinogen urethane using in vivo small-animal magnetic resonance imaging (MRI)...
  6. ncbi request reprint CXCR4 regulates growth of both primary and metastatic breast cancer
    Matthew C P Smith
    Molecular Imaging Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA
    Cancer Res 64:8604-12. 2004
    ..These data indicate that CXCR4 is required to initiate proliferation and/or promote survival of breast cancer cells in vivo and suggest that CXCR4 inhibitors will improve treatment of patients with primary and metastatic breast cancer...
  7. ncbi request reprint Structure, dynamics, and stability of beta-cyclodextrin inclusion complexes of aspartame and neotame
    J R Garbow
    Analytical Sciences Center, Pharmacia Corporation, 800 North Lindbergh Boulevard, St Louis, Missouri 63167, USA
    J Agric Food Chem 49:2053-60. 2001
    ..Solid-state NMR experiments provide additional characterization, clearly demonstrating the formation of inclusion complexes in lyophilized solids prepared from solutions of beta-CyD and either aspartame or neotame...
  8. pmc Frequency-dependent viscoelastic parameters of mouse brain tissue estimated by MR elastography
    E H Clayton
    Department of Mechanical Engineering and Materials Science, Washington University in St Louis, 1 Brookings Drive, Campus Box 1185, Saint Louis, MO 63130, USA
    Phys Med Biol 56:2391-406. 2011
    ..Quantitative measurements of the viscoelastic parameters of brain tissue at high frequencies are also valuable for modeling and simulation of traumatic brain injury...
  9. pmc Orthotopic mouse lung transplantation as experimental methodology to study transplant and tumor biology
    Alexander S Krupnick
    Department of Surgery, Washington University School of Medicine, Campus Box 8234, 660 South Euclid Avenue, St Louis, Missouri 63110, USA
    Nat Protoc 4:86-93. 2009
    ....
  10. pmc Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases
    Beatriz M Carreno
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Cancer Res 15:3277-86. 2009
    ....
  11. ncbi request reprint Registration of [18F]FDG microPET and small-animal MRI
    Douglas J Rowland
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Nucl Med Biol 32:567-72. 2005
    ..Our technique requires no manual identification of image features and makes no use of surgically implanted or external fiducial markers or stereotactic apparatus...
  12. ncbi request reprint Molecular imaging of host-pathogen interactions in intact small animals
    David Piwnica-Worms
    Molecular Imaging Center, Mallinckrodt Institute of Radiology, 510 S Kingshighway Blvd, Box 8225, Washington University, St Louis, MO 63110, USA
    Cell Microbiol 6:319-31. 2004
    ....
  13. pmc MRI detection of early bone metastases in b16 mouse melanoma models
    Karen M Gauvain
    Department of Pediatrics, Division of Hematology Oncology, Washington University School of Medicine, One Children s Place, Box 8116, St Louis, MO 63110, USA
    Clin Exp Metastasis 22:403-11. 2005
    ..0001) and can be used as a marker of early bone metastases. These studies demonstrate that MR imaging can detect bone marrow metastases in small animals prior to development of cortical bone loss identified by X-ray...
  14. ncbi request reprint In vivo imaging in a murine model of glioblastoma
    Sarah C Jost
    Department of Neurosurgery, Washington University, School of Medicine, St Louis, Missouri 63110, USA
    Neurosurgery 60:360-70; discussion 370-1. 2007
    ....
  15. pmc Maintenance of airway epithelium in acutely rejected orthotopic vascularized mouse lung transplants
    Mikio Okazaki
    Department of Surgery, and The Alvin J Siteman Cancer Center, Washington University in St Louis, St Louis, Missouri, USA
    Am J Respir Cell Mol Biol 37:625-30. 2007
    ..Thus, the model of vascularized mouse lung transplantation may provide a new and more physiologic experimental tool to study the interaction between immune and nonimmune mechanisms affecting airway pathology in lung allografts...
  16. pmc Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs
    Yian Wang
    Department of Surgery and The Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Cancer Prev Res (Phila) 2:634-40. 2009
    ..We found that ATB is rapidly absorbed and then distributes to various tissues including the lung. These results indicate that ATB is a potent chemopreventive agent against the development of mouse lung SCCs...
  17. pmc Measuring brain tumor growth: combined bioluminescence imaging-magnetic resonance imaging strategy
    Sarah C Jost
    Department of Neurosurgery, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Mol Imaging 8:245-53. 2009
    ....
  18. pmc Diffusion effects on longitudinal relaxation in poorly mixed compartments
    J R Anderson
    Department of Chemistry, Washington University, St Louis, MO 63130, USA
    J Magn Reson 211:30-6. 2011
    ..In both cases, apparent longitudinal relaxation, though clearly multi-exponential, is well-modeled as bi-exponential...
  19. pmc Detection and measurement of neurofibromatosis-1 mouse optic glioma in vivo
    Debasish Banerjee
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 35:1434-7. 2007
    ..In all cases, OPG presence or absence was correctly identified. In addition, the OPG size and shape were accurately measured in vivo, facilitating the use of this model for preclinical drug studies...
  20. pmc Magnetic resonance imaging of hypoxic injury to the murine placenta
    Tracy M Tomlinson
    Department of Obstetrics and Gynecology, Washington University, St Louis, Missouri, USA
    Am J Physiol Regul Integr Comp Physiol 298:R312-9. 2010
    ..Exposure to hypoxia near the end of mouse pregnancy reduces placental perfusion and clearance of contrast. MRI-based DCE imaging provides a novel tool for dynamic, in vivo assessment of placental function...
  21. ncbi request reprint Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity
    M Livia Bajenaru
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer Res 63:8573-7. 2003
    ..This mouse model demonstrates that Nf1+/- cells contribute to the pathogenesis of gliomas in NF1 and provides a tool for the preclinical evaluation of potential therapeutic interventions for these tumors...
  22. pmc Optic nerve dysfunction in a mouse model of neurofibromatosis-1 optic glioma
    Balazs Hegedus
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neuropathol Exp Neurol 68:542-51. 2009
    ....
  23. ncbi request reprint Hyperpolarized (3)He MRI of mouse lung
    Joseph P Dugas
    Department of Physics, Washington University, St Louis, Missouri 63110, USA
    Magn Reson Med 52:1310-7. 2004
    ..While tumors are shown to cause substantial ventilation defects in the lung, these defects appear confined to the cancerous regions and do not extend to large-scale regions of the lung distal to the tumors...
  24. ncbi request reprint Nondestructive NMR determination of oil composition in transformed canola seeds
    W C Hutton
    Nutrition and Consumer Sector, Monsanto, St Louis, Missouri 63167, USA
    Lipids 34:1339-46. 1999
    ..These NMR methods are nondestructive and attractive for plant-breeding programs or other studies (e.g., functional genomics) where loss of seed viability is inconvenient...
  25. ncbi request reprint NMR studies of structure and dynamics in fruit cuticle polyesters
    R E Stark
    Department of Chemistry, College of Staten Island and the Graduate School of the City University of New York, NY 10314, USA
    Solid State Nucl Magn Reson 16:37-45. 2000
    ....
  26. ncbi request reprint A mouse model for developing treatment for secondary liver tumors
    Shi Rong Cai
    Departmen of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Oncol 27:113-20. 2005
    ....
  27. ncbi request reprint Copper-64-pyruvaldehyde-bis(N(4)-methylthiosemicarbazone) for the prevention of tumor growth at wound sites following laparoscopic surgery: monitoring therapy response with microPET and magnetic resonance imaging
    Jason S Lewis
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer Res 62:445-9. 2002
    ..001). This study demonstrates the therapeutic potential of (64)Cu-PTSM in inhibiting cancer cell implantation and growth at doses well below the maximum tolerated dose, with no signs of toxicity to the hamsters...
  28. doi request reprint Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma
    Balazs Hegedus
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Cancer Res 68:1520-8. 2008
    ..Collectively, these findings suggest that this Nf1 optic glioma model may be a potential preclinical benchmark for identifying novel therapies that have a high likelihood of success in human clinical trials...
  29. pmc A novel murine model for localized radiation necrosis and its characterization using advanced magnetic resonance imaging
    Sarah C Jost
    Department of Neurosurgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 75:527-33. 2009
    ..To develop a murine model of radiation necrosis using fractionated, subtotal cranial irradiation; and to investigate the imaging signature of radiation-induced tissue damage using advanced magnetic resonance imaging techniques...
  30. pmc A novel technology for the imaging of acidic prostate tumors by positron emission tomography
    Amy L Vavere
    Division of Radiological Sciences, Department of Radiology, Washington University School of Medicine, St Louis, MO, USA
    Cancer Res 69:4510-6. 2009
    ..This article introduces a novel class of noninvasive pH-selective positron emission tomography imaging agents and opens new research directions in the diagnosis of acidic solid tumors...
  31. ncbi request reprint Natural history of neurofibromatosis 1-associated optic nerve glioma in mice
    M Livia Bajenaru
    Department of Neurology, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Ann Neurol 57:119-27. 2005
    ..Last, we observed neovascularization and microglial cell infiltration by 3 weeks of age before overt neoplastic transformation, suggesting that these cellular changes participate in the early stages of tumor formation...
  32. ncbi request reprint Synthesis and characterization of a Gd-DOTA-D-permeation peptide for magnetic resonance relaxation enhancement of intracellular targets
    Andrew M Prantner
    Washington University School of Medicine, St Louis, MO 63110, USA
    Mol Imaging 2:333-41. 2003
    ....
  33. pmc Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1
    Nicole M Warrington
    Department of Pediatrics, Molecular Imaging Center, Mallinckrodt Institute of Radiology, Developmental Biology, and Anatomy and Neurobiology, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri 63110, USA
    Cancer Res 70:5717-27. 2010
    ..Together, these results indicate that low levels of cAMP in a susceptible Nf1 mouse strain are sufficient to promote gliomagenesis, and justify the implementation of cAMP-based stroma-targeted therapies for glioma...
  34. pmc Feasibility of small animal cranial irradiation with the microRT system
    Erich L Kiehl
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 35:4735-43. 2008
    ..To develop and validate methods for small-animal CNS radiotherapy using the microRT system...
  35. pmc Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice
    Marshall W Anderson
    Department of Molecular Oncogenesis, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA
    Carcinogenesis 29:1594-600. 2008
    ..Our results suggest a potential role for green tea extracts in preventing the progression of large, aggressive lung adenocarcinomas...
  36. pmc Hydrochalarones: a novel endohedral metallofullerene platform for enhancing magnetic resonance imaging contrast
    Darren K MacFarland
    Luna nanoWorks A Division of Luna Innovations, Incorporated, 521 Bridge Street, Danville, Virginia 24541, USA
    J Med Chem 51:3681-3. 2008
    ..These new compounds can be used to visualize tissue architecture in vivo with standard MRI techniques...
  37. pmc Rethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop
    Karlyne M Reilly
    Mouse Cancer Genetics Program, National Cancer Institute, Frederick, Maryland 21702, USA
    Cancer Res 68:5508-11. 2008