Michael S Gaffrey

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Disrupted amygdala reactivity in depressed 4- to 6-year-old children
    Michael S Gaffrey
    Washington University, School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 52:737-46. 2013
  2. pmc Towards the study of functional brain development in depression: an Interactive Specialization approach
    Michael S Gaffrey
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA
    Neurobiol Dis 52:38-48. 2013
  3. pmc Default mode network connectivity in children with a history of preschool onset depression
    Michael S Gaffrey
    Department of Psychiatry, Washington University in St Louis, Saint Louis, MO 63110, USA
    J Child Psychol Psychiatry 53:964-72. 2012
  4. pmc Association between depression severity and amygdala reactivity during sad face viewing in depressed preschoolers: an fMRI study
    Michael S Gaffrey
    Washington University School of Medicine, Department of Psychiatry, Saint Louis, MO 63110, United States
    J Affect Disord 129:364-70. 2011
  5. pmc Subgenual cingulate connectivity in children with a history of preschool-depression
    Michael S Gaffrey
    Departments of Psychiatry, Washington University, St Louis, Missouri, USA
    Neuroreport 21:1182-8. 2010
  6. pmc The 2-week duration criterion and severity and course of early childhood depression: implications for nosology
    Michael S Gaffrey
    Washington University School of Medicine, Department of Psychiatry, Saint Louis, Missouri 63110, USA
    J Affect Disord 133:537-45. 2011
  7. pmc Structural-functional correlations between hippocampal volume and cortico-limbic emotional responses in depressed children
    Hideo Suzuki
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Cogn Affect Behav Neurosci 13:135-51. 2013
  8. pmc Functional connectivity of the amygdala in early-childhood-onset depression
    Katherine R Luking
    Department of Psychology, Washington University in St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 50:1027-41.e3. 2011
  9. pmc Functional brain activation to emotionally valenced faces in school-aged children with a history of preschool-onset major depression
    Deanna M Barch
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA
    Biol Psychiatry 72:1035-42. 2012
  10. doi request reprint Stress-system genes and life stress predict cortisol levels and amygdala and hippocampal volumes in children
    David Pagliaccio
    Program in Neuroscience, Washington University in St Louis, St Louis, MO, USA
    Neuropsychopharmacology 39:1245-53. 2014

Detail Information

Publications14

  1. pmc Disrupted amygdala reactivity in depressed 4- to 6-year-old children
    Michael S Gaffrey
    Washington University, School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 52:737-46. 2013
    ..The current study addressed this question by examining functional brain activity and its relationships to emotion regulation in depressed 4- to 6-year-old children and their healthy peers...
  2. pmc Towards the study of functional brain development in depression: an Interactive Specialization approach
    Michael S Gaffrey
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA
    Neurobiol Dis 52:38-48. 2013
    ..Future directions including longitudinal neuroimaging studies of early onset depression and groups at risk for this disorder are proposed...
  3. pmc Default mode network connectivity in children with a history of preschool onset depression
    Michael S Gaffrey
    Department of Psychiatry, Washington University in St Louis, Saint Louis, MO 63110, USA
    J Child Psychol Psychiatry 53:964-72. 2012
    ..The current case-control study examined the DMN in a unique prospective sample of school-age children with a previous history of preschool depression...
  4. pmc Association between depression severity and amygdala reactivity during sad face viewing in depressed preschoolers: an fMRI study
    Michael S Gaffrey
    Washington University School of Medicine, Department of Psychiatry, Saint Louis, MO 63110, United States
    J Affect Disord 129:364-70. 2011
    ..Previous research has indicated that symptom severity and amygdala reactivity during the viewing of facial expressions of emotion are related in depression. However, it remains unclear how early in development this can be detected...
  5. pmc Subgenual cingulate connectivity in children with a history of preschool-depression
    Michael S Gaffrey
    Departments of Psychiatry, Washington University, St Louis, Missouri, USA
    Neuroreport 21:1182-8. 2010
    ..These findings demonstrate that atypical sgACC functional connections are evident as early as school age in children with a history of PO-MDD and suggest an association with a very early episode of depression...
  6. pmc The 2-week duration criterion and severity and course of early childhood depression: implications for nosology
    Michael S Gaffrey
    Washington University School of Medicine, Department of Psychiatry, Saint Louis, Missouri 63110, USA
    J Affect Disord 133:537-45. 2011
    ..The current study aimed to begin addressing this question...
  7. pmc Structural-functional correlations between hippocampal volume and cortico-limbic emotional responses in depressed children
    Hideo Suzuki
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Cogn Affect Behav Neurosci 13:135-51. 2013
    ..These findings suggest that there may be important interrelationships between reduced hippocampal volume and hyperactivation of brain responses in children, both those with and those without a history of PO-MDD...
  8. pmc Functional connectivity of the amygdala in early-childhood-onset depression
    Katherine R Luking
    Department of Psychology, Washington University in St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 50:1027-41.e3. 2011
    ..However, it is unclear whether such connectivity alterations are also present in early-childhood-onset MDD...
  9. pmc Functional brain activation to emotionally valenced faces in school-aged children with a history of preschool-onset major depression
    Deanna M Barch
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA
    Biol Psychiatry 72:1035-42. 2012
    ..Recent research has demonstrated that clinical depression can emerge as early as the preschool period. Here, we examine brain function in children with a history of preschool-onset depression (PO-MDD) in comparison with healthy children...
  10. doi request reprint Stress-system genes and life stress predict cortisol levels and amygdala and hippocampal volumes in children
    David Pagliaccio
    Program in Neuroscience, Washington University in St Louis, St Louis, MO, USA
    Neuropsychopharmacology 39:1245-53. 2014
    ..These results suggest that stress-related genetic and early environmental factors contribute to variation in stress cortisol reactivity and limbic brain volumes in children, phenotypes associated with depression in adulthood. ..
  11. pmc Maternal support in early childhood predicts larger hippocampal volumes at school age
    Joan L Luby
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 109:2854-9. 2012
    ..These findings provide prospective evidence in humans of the positive effect of early supportive parenting on healthy hippocampal development, a brain region key to memory and stress modulation...
  12. doi request reprint Serotonin transporter-linked polymorphic region (5-HTTLPR) genotype and stressful life events interact to predict preschool-onset depression: a replication and developmental extension
    Ryan Bogdan
    Department of Psychology, Washington University in St Louis, St Louis, MO, USA Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA
    J Child Psychol Psychiatry 55:448-57. 2014
    ....
  13. pmc Functional brain activation to emotional and nonemotional faces in healthy children: evidence for developmentally undifferentiated amygdala function during the school-age period
    David Pagliaccio
    Program in Neuroscience, Washington University, St Louis, Missouri, USA
    Cogn Affect Behav Neurosci 13:771-89. 2013
    ..Additionally, sex differences were observed in frontal, temporal, and visual regions, as well as effects of pubertal development in visual regions. These findings suggest important differences in amygdala reactivity in childhood...
  14. pmc Relational aggression in children with preschool-onset psychiatric disorders
    Andy C Belden
    Early Emotional Development Program, Washington University School of Medicine in St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 51:889-901. 2012
    ..The role of preschool-onset (PO) psychiatric disorders as correlates and/or risk factors for relational aggression during kindergarten or first grade was tested in a sample of 146 preschool-age children (age 3 to 5.11 years)...