Kenneth Freedland

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Depression as a risk factor for adverse outcomes in coronary heart disease
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Avenue, St Louis, MO 63108, USA
    BMC Med 11:131. 2013
  2. pmc Effect of obstructive sleep apnea on response to cognitive behavior therapy for depression after an acute myocardial infarction
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    J Psychosom Res 72:276-81. 2012
  3. pmc Effect of depression on prognosis in heart failure
    Kenneth E Freedland
    Department of Psychiatry, Behavioral Medicine Center, Washington University School of Medicine, 4320 Forest Park Avenue, St Louis, MO 63108, USA
    Heart Fail Clin 7:11-21. 2011
  4. doi request reprint Treatment of depression after coronary artery bypass surgery: a randomized controlled trial
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Ste 301, St Louis, MO 63108, USA
    Arch Gen Psychiatry 66:387-96. 2009
  5. pmc Usual and unusual care: existing practice control groups in randomized controlled trials of behavioral interventions
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Suite 301, St Louis, Missouri 63108, USA
    Psychosom Med 73:323-35. 2011
  6. ncbi request reprint Religious beliefs shorten hospital stays? Psychology works in mysterious ways: comment on Contrada et al. (2004)
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Health Psychol 23:239-42. 2004
  7. doi request reprint Multivariable models in biobehavioral research
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Suite 301, St Louis, Missouri 63108, USA
    Psychosom Med 71:205-16. 2009
  8. ncbi request reprint Circadian and ultradian rhythms in heart rate variability
    Phyllis K Stein
    1 Division of Cardiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Biomed Tech (Berl) 51:155-8. 2006
  9. ncbi request reprint Prevalence of depression in hospitalized patients with congestive heart failure
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63124, USA
    Psychosom Med 65:119-28. 2003
  10. ncbi request reprint Pathways linking depression, adiposity, and inflammatory markers in healthy young adults
    Gregory E Miller
    Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
    Brain Behav Immun 17:276-85. 2003

Detail Information

Publications76

  1. pmc Depression as a risk factor for adverse outcomes in coronary heart disease
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Avenue, St Louis, MO 63108, USA
    BMC Med 11:131. 2013
    ..In addition, research on biobehavioral mechanisms has not yet produced a definitive causal model of the relationship between depression and cardiac outcomes...
  2. pmc Effect of obstructive sleep apnea on response to cognitive behavior therapy for depression after an acute myocardial infarction
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    J Psychosom Res 72:276-81. 2012
    ..To determine whether obstructive sleep apnea (OSA) interferes with cognitive behavior therapy (CBT) for depression in patients with coronary heart disease...
  3. pmc Effect of depression on prognosis in heart failure
    Kenneth E Freedland
    Department of Psychiatry, Behavioral Medicine Center, Washington University School of Medicine, 4320 Forest Park Avenue, St Louis, MO 63108, USA
    Heart Fail Clin 7:11-21. 2011
    ..Further research is needed to clarify the relationships among depression, heart failure, and adverse outcomes, as well as to develop efficacious interventions for depressive disorders in patients with heart failure...
  4. doi request reprint Treatment of depression after coronary artery bypass surgery: a randomized controlled trial
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Ste 301, St Louis, MO 63108, USA
    Arch Gen Psychiatry 66:387-96. 2009
    ..There has been little research on the treatment of depression after coronary artery bypass surgery...
  5. pmc Usual and unusual care: existing practice control groups in randomized controlled trials of behavioral interventions
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Suite 301, St Louis, Missouri 63108, USA
    Psychosom Med 73:323-35. 2011
    ..To evaluate the use of existing practice control groups in randomized controlled trials of behavioral interventions and the role of extrinsic health care services in the design and conduct of behavioral trials...
  6. ncbi request reprint Religious beliefs shorten hospital stays? Psychology works in mysterious ways: comment on Contrada et al. (2004)
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Health Psychol 23:239-42. 2004
    ..Why? What determines the importance of psychosocial predictors of medical outcomes? How can health psychologists increase the impact of biopsychosocial research?..
  7. doi request reprint Multivariable models in biobehavioral research
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Suite 301, St Louis, Missouri 63108, USA
    Psychosom Med 71:205-16. 2009
    ..To review contemporary multivariable modeling and statistical reporting practices in psychosomatic and behavioral medicine research...
  8. ncbi request reprint Circadian and ultradian rhythms in heart rate variability
    Phyllis K Stein
    1 Division of Cardiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Biomed Tech (Berl) 51:155-8. 2006
    ..While overall and circadian heart rate (HR) and HRV are well characterized by traditional measures, there is currently no method to measure ultradian cycles of HR and HRV...
  9. ncbi request reprint Prevalence of depression in hospitalized patients with congestive heart failure
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63124, USA
    Psychosom Med 65:119-28. 2003
    ..This article reports the prevalence of depression in a larger sample of hospitalized patients with CHF and identifies demographic, medical, psychosocial, and methodological factors that may affect prevalence estimates...
  10. ncbi request reprint Pathways linking depression, adiposity, and inflammatory markers in healthy young adults
    Gregory E Miller
    Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
    Brain Behav Immun 17:276-85. 2003
    ..99; NNFI =.99; RMSEA =.05). It did not support a sickness behavior model in which the inflammatory molecules arising from expanded adipose tissue promote depressive symptoms...
  11. pmc Heart rate variability and markers of inflammation and coagulation in depressed patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    J Psychosom Res 62:463-7. 2007
    ..Cardiac autonomic nervous system (ANS) dysregulation, proinflammatory processes, and procoagulant processes have been suggested as possible explanations...
  12. ncbi request reprint Coronary heart disease and depression: a review of recent mechanistic research
    Judith A Skala
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Can J Psychiatry 51:738-45. 2006
    ..Both behavioural and physiological factors have been proposed as mechanisms that may explain the negative effect of depression on coronary heart disease (CHD). Our aim is to review some of the most important findings since our prior review...
  13. ncbi request reprint Depression and obstructive sleep apnea in patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychosom Med 68:443-8. 2006
    ..Obstructive sleep apnea/hypopnea syndrome (OSAHS) is frequently comorbid with depression and is also a risk factor for cardiac events. Undetected OSAHS could help explain the increased risk associated with depression...
  14. ncbi request reprint Sertraline for prevention of depression recurrence in diabetes mellitus: a randomized, double-blind, placebo-controlled trial
    Patrick J Lustman
    Department of Veterans Affairs Medical Center, St Louis, MO, USA
    Arch Gen Psychiatry 63:521-9. 2006
    ..In patients with diabetes mellitus, depression is a prevalent and recurrent problem that adversely affects the medical prognosis...
  15. ncbi request reprint Heart rate turbulence, depression, and survival after acute myocardial infarction
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Psychosom Med 69:4-9. 2007
    ..e., abnormal turbulence) to premature ventricular contractions (VPCs), and b) whether abnormal HR turbulence accounts for the effect of depression on increased mortality after AMI...
  16. ncbi request reprint Low heart rate variability and the effect of depression on post-myocardial infarction mortality
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Arch Intern Med 165:1486-91. 2005
    ..Depression is associated with an increased risk for mortality after acute myocardial infarction (MI). The purpose of this study was to determine whether low heart rate variability (HRV) mediates the effect of depression on mortality...
  17. ncbi request reprint Depression and smoking in coronary heart disease
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, 4625 Lindell Blvd, Suite 420, St Louis, MO 63108, USA
    Psychosom Med 67:S42-6. 2005
    ....
  18. ncbi request reprint Depression, the autonomic nervous system, and coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Psychosom Med 67:S29-33. 2005
    ....
  19. ncbi request reprint Does treating depression improve survival after acute coronary syndrome? Invited commentary on... Effects of antidepressant treatment following myocardial infarction
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, Missouri, USA
    Br J Psychiatry 190:467-8. 2007
    ..More effective treatments for depression will have to be developed if this hypothesis is to be tested with sufficient power in attainable samples...
  20. ncbi request reprint Circadian and ultradian rhythms in cardiac autonomic modulation
    Phyllis K Stein
    Washington University School of Medicine, St Louis, MO 63108, USA
    Conf Proc IEEE Eng Med Biol Soc 1:429-32. 2006
    ..We have developed a method for capturing these rhythms during sleep and have now applied it to 24-hour recordings...
  21. pmc Effect of omega-3 fatty acids on heart rate variability in depressed patients with coronary heart disease
    Robert M Carney
    Behavioral Medicine Center, Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Avenue, Suite 301, St Louis, MO 63108, USA
    Psychosom Med 72:748-54. 2010
    ..Low intake of omega-3 FAs is associated with depression and with low HRV, and all three are associated with an increased risk of death in patients with CHD...
  22. doi request reprint Anxiety disorders increase risk for incident myocardial infarction in depressed and nondepressed Veterans Administration patients
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, MO, USA
    Am Heart J 159:772-9. 2010
    ..Depression is a risk factor for incident myocardial infarction (MI), but little is known about the independent or additive risk from anxiety disorders...
  23. pmc Omega-3 augmentation of sertraline in treatment of depression in patients with coronary heart disease: a randomized controlled trial
    Robert M Carney
    Behavioral Medicine Center, Department of Psychiatry, Washington University School of Medicine, 4320 Forest Park Ave, Ste 301, St Louis, MO 63108, USA
    JAMA 302:1651-7. 2009
    ..Studies of depressed psychiatric patients have shown that antidepressant efficacy can be increased by augmentation with omega-3 fatty acids...
  24. pmc Depression and heart rate variability in patients with coronary heart disease
    Robert M Carney
    Behavioral Medicine Center, 4320 Forest Park Boulevard, Suite 301, St Louis, MO 63108, USA
    Cleve Clin J Med 76:S13-7. 2009
    ..This manuscript provides an overview of this literature and concludes that HRV may account for a substantial part of the risk associated with depression in CHD...
  25. pmc Treatment-resistant depression and mortality after acute coronary syndrome
    Robert M Carney
    Behavioral Medicine Center, 4320 Forest Park Blvd Suite 301, St Louis, MO 63108, USA
    Am J Psychiatry 166:410-7. 2009
    ..Directions for future research are also considered, with particular emphasis on efforts to elucidate the underlying mechanisms and to develop more efficacious treatments for depression in patients with coronary heart disease...
  26. pmc History of depression and survival after acute myocardial infarction
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychosom Med 71:253-9. 2009
    ..Recent reports suggest that the level of risk may depend on whether the comorbid MD is a first or a recurrent episode...
  27. doi request reprint Depression in patients with coronary heart disease
    Robert M Carney
    Behavioral Medicine Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Am J Med 121:S20-7. 2008
    ..This article describes screening techniques for use in primary care and cardiology settings, and discusses the safety and efficacy of available treatments for depression in patients with CHD...
  28. pmc Nighttime heart rate and survival in depressed patients post acute myocardial infarction
    Robert M Carney
    Departments of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychosom Med 70:757-63. 2008
    ..It is also associated with sleep disturbances and with elevated HR, which may be more pronounced at night. Resting and 24-hour HR have been found to predict mortality in patient and community samples...
  29. pmc Depression and five year survival following acute myocardial infarction: a prospective study
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, United States
    J Affect Disord 109:133-8. 2008
    ..Even minor depression is associated with an increased risk. Although it is not known whether treating depression can improve survival, patients with depression should be recognized as being at increased risk long after their acute MI...
  30. ncbi request reprint Cardiac autonomic modulation. Analyzing circadian and ultradian rhythms
    Phyllis K Stein
    Washington University School of Medicine, St Louis, MO 63108, USA
    IEEE Eng Med Biol Mag 26:14-8. 2007
  31. ncbi request reprint Depression-related hyperglycemia in type 1 diabetes: a mediational approach
    Patrick J Lustman
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Psychosom Med 67:195-9. 2005
    ..In this study, we applied mediational analysis methods to determine whether the hyperglycemic effect of depression could be mediated by poor diabetes self-care...
  32. ncbi request reprint Depression and late mortality after myocardial infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study
    Robert M Carney
    Department of Psychiatry, Behavioral Medicine Center, Washington University School of Medicine, St Louis, MO 63108, USA
    Psychosom Med 66:466-74. 2004
    ..It also examines the relationship between change in depression and late mortality...
  33. ncbi request reprint Gender influence on cognitive function after cardiac operation
    Charles W Hogue
    Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Ann Thorac Surg 76:1119-25. 2003
    ..Women are at higher risk than men for stroke after cardiac operation. The purpose of this study was to evaluate for gender influences on the more common postoperative neurologic complication, cognitive dysfunction...
  34. ncbi request reprint Depression, mortality, and medical morbidity in patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Biol Psychiatry 54:241-7. 2003
    ..The relationship is most apparent for patients with a recent acute myocardial infarction. Many questions about the impact of depression on heart disease remain unresolved...
  35. ncbi request reprint Depression and coronary heart disease in women with diabetes
    Ray E Clouse
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Psychosom Med 65:376-83. 2003
    ..Depression predicts onset of and poor outcome from CHD in nondiabetic populations. We hypothesized that the doubled rates of depression in female diabetic patients could help explain the high prevalence of CHD in women with diabetes...
  36. ncbi request reprint Death takes a raincheck
    Judith A Skala
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Psychosom Med 66:382-6. 2004
    ..To review the research literature on temporal variation in mortality rates around symbolically important occasions...
  37. doi request reprint Depression increases risk of incident myocardial infarction among Veterans Administration patients with rheumatoid arthritis
    Jeffrey F Scherrer
    Research Service, St Louis Veterans Affairs Medical Center, St Louis, MO 63106, USA
    Gen Hosp Psychiatry 31:353-9. 2009
    ..This study evaluates whether depression is a risk factor for incident myocardial infarction (MI) in Department of Veterans Affairs (VA) patients with rheumatoid arthritis (RA) between 30 and 79 years of age...
  38. ncbi request reprint Clinical depression and inflammatory risk markers for coronary heart disease
    Gregory E Miller
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    Am J Cardiol 90:1279-83. 2002
    ..Increased body mass appears to be partially, although not completely, responsible for this relation...
  39. ncbi request reprint Depression as a risk factor for mortality after acute myocardial infarction
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Am J Cardiol 92:1277-81. 2003
    ..In conclusion, depression was an independent risk factor for death after AMI, but it did not have a significant effect on mortality until nearly 12 months after the acute event, nor did it predict nonfatal recurrent infarction...
  40. ncbi request reprint Depression predicts self-reported sleep quality in patients with obstructive sleep apnea
    Rachel D Wells
    Department of Psychology, Washington University, One Brookings Drive, Campus Box 1125, St Louis, Missouri 63130 4899, USA
    Psychosom Med 66:692-7. 2004
    ..The objective of this study was to examine whether depression is independently associated with lower self-reported sleep quality in patients with obstructive sleep apnea (OSA), after controlling for polysomnographic measures of sleep...
  41. ncbi request reprint Depression as a risk factor for cardiac mortality and morbidity: a review of potential mechanisms
    Robert M Carney
    Department of Psychiatry, Suite 420, Behavioral Medicine Center, Washington University School of Medicine, 4625 Lindell Boulevard, St Louis, MO 63108, USA
    J Psychosom Res 53:897-902. 2002
    ..inflammatory processes. Despite recent advances in our understanding of these potential mechanisms, further research is needed to determine how depression increases risk for cardiac morbidity and mortality...
  42. ncbi request reprint Heart disease attributions: introduction to the miniseries
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Int J Behav Med 12:21-3. 2005
  43. ncbi request reprint Effects of depression on QT interval variability after myocardial infarction
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychosom Med 65:177-80. 2003
    ..The purpose of this study was to determine whether depression is associated with increased QT variability in patients recovering from myocardial infarction...
  44. doi request reprint Antidepressant drug compliance: reduced risk of MI and mortality in depressed patients
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, St Louis, MO, USA
    Am J Med 124:318-24. 2011
    ..The present study uses a national Veterans Affairs cohort to test whether antidepressants increase or decrease risk of MI and all-cause mortality...
  45. pmc Preexisting cognitive impairment in women before cardiac surgery and its relationship with C-reactive protein concentrations
    Charles W Hogue
    Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri, USA
    Anesth Analg 102:1602-8; table of contents. 2006
    ....
  46. ncbi request reprint Anxiety and poor glycemic control: a meta-analytic review of the literature
    Ryan J Anderson
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Int J Psychiatry Med 32:235-47. 2002
    ..To determine whether anxiety is associated with poor glycemic control in adults with type 1 or type 2 diabetes...
  47. pmc Antidepressant pharmacotherapy in adults with type 2 diabetes: rates and predictors of initial response
    Ryan J Anderson
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Diabetes Care 33:485-9. 2010
    ..CONCLUSIONS In patients with type 2 diabetes, poor initial response to antidepressant medication is predicted by multiple factors. Auxiliary treatment of pain and impairment may be required to achieve better outcomes...
  48. ncbi request reprint The Depression Interview and Structured Hamilton (DISH): rationale, development, characteristics, and clinical validity
    Kenneth E Freedland
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychosom Med 64:897-905. 2002
    ..This article describes the development and characteristics of the DISH and presents a validity study and data on its use in ENRICHD...
  49. ncbi request reprint Prevalence of anxiety in adults with diabetes: a systematic review
    Allison B Grigsby
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Psychosom Res 53:1053-60. 2002
    ..Anxiety is associated with decreased functioning and quality of life. It may have added importance in diabetes for its potential adverse effects on regimen adherence and glycemic control...
  50. ncbi request reprint Adherence, reports of benefits, and depression among patients treated with continuous positive airway pressure
    Rachel D Wells
    Behavioral Medicine Institute, St Louis, MO 63110, USA
    Psychosom Med 69:449-54. 2007
    ..CPAP is a highly effective treatment for OSA. Low adherence to CPAP therapy is common and poorly understood. Depression and lack of perceived benefits from CPAP are possible reasons for low adherence...
  51. ncbi request reprint Effects of anxiety and depression on heart disease attributions
    Ryan C Day
    Department of Psychology, Washington University, St Louis, Missouri 63108, USA
    Int J Behav Med 12:24-9. 2005
    ..We conclude that mood state influences cardiac patients' beliefs about the causes of their heart disease...
  52. ncbi request reprint Predictors of mortality in younger and older patients with heart failure and preserved or reduced left ventricular ejection fraction
    Roger Kerzner
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Am Heart J 146:286-90. 2003
    ..Although half of elderly patients with heart failure have preserved left ventricular ejection fraction (LVEF), little is known about predictors of mortality in this group...
  53. ncbi request reprint Cognitive and somatic symptoms of depression are associated with medical comorbidity in patients after acute myocardial infarction
    Lana L Watkins
    Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA
    Am Heart J 146:48-54. 2003
    ..However, the extent to which clinical depression is related to comorbid medical conditions is unknown. This study examined the degree of association between clinical depression and medical comorbidity in patients hospitalized with AMI...
  54. ncbi request reprint Medical disorders among patients admitted to a public-sector psychiatric inpatient unit
    Lorrin M Koran
    Department of Psychiatry and Behavioral Science, OCD Clinic, Stanford University Medical Center, Room 2363, 401 Quarry Road, Stanford, CA 94305, USA
    Psychiatr Serv 53:1623-5. 2002
    ..5 percent of the patients, respectively. Patients admitted to psychiatric inpatient units should be carefully evaluated for physical disease...
  55. doi request reprint Depressive symptoms predict heart rate recovery after exercise treadmill testing in patients with coronary artery disease: results from the Psychophysiological Investigation of Myocardial Ischemia study
    Joel W Hughes
    Kent State University, Kent, Ohio, USA
    Psychosom Med 70:456-60. 2008
    ..The purpose of this study was to determine whether depressive symptoms are associated with low heart rate variability (HRV) and prolonged HR recovery after exercise testing in patients with coronary artery disease (CAD)...
  56. ncbi request reprint Aspects of social support associated with depression at hospitalization and follow-up assessment among cardiac patients
    John C Barefoot
    Duke University Medical Center, Durham, NC 27710, USA
    J Cardiopulm Rehabil 23:404-12. 2003
    ..This study examined various aspects of social support as they relate to depressive symptoms in patients with MI, both in the hospital and 2 weeks later...
  57. ncbi request reprint Predictors of treatment response for depression and inadequate social support--the ENRICHD randomized clinical trial
    Marie J Cowan
    School of Nursing, University of California at Los Angeles, Los Angeles, Calif 90095 1702, USA
    Psychother Psychosom 77:27-37. 2008
    ....
  58. ncbi request reprint Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute working group report
    Karina W Davidson
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA, and Centre Hospitalier de l Universite de Montreal Research Center, Quebec, Canada
    Ann Behav Med 32:121-6. 2006
  59. ncbi request reprint Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study
    Allan S Jaffe
    Cardiovascular Division, Mayo Clinic, Rochester, MN 55905, USA
    Am Heart J 152:126-35. 2006
    ....
  60. ncbi request reprint Telephone-based coping skills training for patients awaiting lung transplantation
    James A Blumenthal
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    J Consult Clin Psychol 74:535-44. 2006
    ..Despite the severity of pulmonary disease in this patient population, significant improvements in quality of life, but not somatic measures or survival to transplant, were achieved...
  61. ncbi request reprint Depressive symptoms and the regulation of proinflammatory cytokine expression in patients with coronary heart disease
    Gregory E Miller
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver BC, Canada V6T 1Z4
    J Psychosom Res 59:231-6. 2005
    ..This study examined whether depressive symptoms are associated with the dysregulation of inflammatory cytokine production in response to an in vitro infectious challenge...
  62. ncbi request reprint The INTERHEART study: intersection between behavioral and general medicine
    David S Sheps
    Psychosom Med 66:797-8. 2004
  63. ncbi request reprint Depression following myocardial infarction
    Robert M Carney
    Gen Hosp Psychiatry 27:381-2. 2005
  64. ncbi request reprint Depression is a risk factor for mortality in coronary heart disease
    Robert M Carney
    Psychosom Med 66:799-801. 2004
  65. ncbi request reprint Relation of depressive symptoms to C-reactive protein and pathogen burden (cytomegalovirus, herpes simplex virus, Epstein-Barr virus) in patients with earlier acute coronary syndromes
    Gregory E Miller
    Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Cardiol 95:317-21. 2005
    ..In doing so, they highlight a mechanism through which depressive symptoms might foster morbidity and mortality among patients who have cardiac disease...
  66. ncbi request reprint Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group Report
    Karina W Davidson
    Department of Medicine, Columbia University College of Physicians and Surgeons, 622 W 168th St, PH9 Center, Room 941, New York, NY 10032, USA
    Psychosom Med 68:645-50. 2006
    ..The National Heart, Lung, and Blood Institute convened an interdisciplinary working group of experts to develop recommendations for the assessment and treatment of depression in patients with coronary heart disease (CHD)...
  67. ncbi request reprint Depression and heart failure in patients with a new myocardial infarction
    Lynda H Powell
    Department of Preventive Medicine, Rush University Medical Center, Chicago, Ill 60614, USA
    Am Heart J 149:851-5. 2005
    ..This investigation compared the prevalence of depression in patients with and without HF who were hospitalized with myocardial infarction (MI) and also at high psychosocial risk...
  68. pmc Coping and quality of life in patients awaiting lung transplantation
    Jessica L Taylor
    Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC 27710, USA
    J Psychosom Res 65:71-9. 2008
    ..Although coping strategies are related to QOL in patients with ESLD, the extent to which specific native lung disease moderates this relationship is unknown...
  69. ncbi request reprint Depression and coronary heart disease: more pieces of the puzzle
    Robert M Carney
    Am J Psychiatry 164:1307-9. 2007
  70. ncbi request reprint Cynical hostility, depressive symptoms, and the expression of inflammatory risk markers for coronary heart disease
    Gregory E Miller
    Department of Psychology, Washington University, Saint Louis, Missouri, USA
    J Behav Med 26:501-15. 2003
    ..These findings highlight the importance of considering both the independent and interactive relationships among psychosocial characteristics involved in disease...
  71. ncbi request reprint The effect of a psychosocial intervention and quality of life after acute myocardial infarction: the Enhancing Recovery in Coronary Heart Disease (ENRICHD) clinical trial
    Carlos F Mendes de Leon
    Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Cardiopulm Rehabil 26:9-13; quiz 14-5. 2006
    ..This report analyzes the effect of the intervention on quality of life (QOL), which was an important secondary outcome...
  72. ncbi request reprint Probable need for psychiatric treatment is not the same as depression
    Nancy Frasure-Smith
    Eur Heart J 25:994-5; author reply 995-6. 2004
  73. ncbi request reprint Does living alone affect the outcome of acute myocardial infarction?
    Kenneth E Freedland
    Am J Cardiol 91:1040. 2003
  74. ncbi request reprint Psychological distress as a risk factor for stroke-related mortality
    Robert M Carney
    Stroke 33:5-6. 2002
  75. ncbi request reprint ENRICHD and SADHART: implications for future biobehavioral intervention efforts
    David S Sheps
    Psychosom Med 65:1-2. 2003
  76. ncbi request reprint Depression as a risk factor for post-MI mortality
    Robert M Carney
    J Am Coll Cardiol 44:472; author reply 473-4. 2004

Research Grants11

  1. TREATMENT OF FUNCTIONAL IMPAIRMENT IN PATIENTS WITH HEART FAILURE AND COMORBID DE
    Kenneth Freedland; Fiscal Year: 2009
    ..The effects of treatment on other outcomes such as physical activity and rehospitalizations will also be investigated. ..
  2. Effects of Depression on Short-Term Recovery from MI
    Kenneth Freedland; Fiscal Year: 2007
    ..The results will clarify the early course of post-MI depression and the mechanisms linking depression to cardiac events, and they will inform efforts to develop more efficacious treatments. ..
  3. Treatment of Depression After Coronary Bypass Surgery
    Kenneth Freedland; Fiscal Year: 2004
    ..Secondary analyses will test the effects of treatment on remission, neurocognitive and functional recovery, quality of life, and examine the relationships between treatment process and outcome variables. ..
  4. TREATMENT OF FUNCTIONAL IMPAIRMENT IN PATIENTS WITH HEART FAILURE AND COMORBID DE
    Kenneth E Freedland; Fiscal Year: 2010
    ..The effects of treatment on other outcomes such as physical activity and rehospitalizations will also be investigated. ..