Erik R Dubberke

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Burden of Clostridium difficile on the healthcare system
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Infect Dis 55:S88-92. 2012
  2. doi request reprint Clostridium difficile infection: the scope of the problem
    Erik Dubberke
    Division of Infectious Disease, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Hosp Med 7:S1-4. 2012
  3. doi request reprint Strategies for prevention of Clostridium difficile infection
    Erik Dubberke
    Division of Infectious Disease, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Hosp Med 7:S14-7. 2012
  4. pmc Implementing automated surveillance for tracking Clostridium difficile infection at multiple healthcare facilities
    Erik R Dubberke
    Washington University School of Medicine, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 33:305-8. 2012
  5. pmc Prevention of healthcare‐associated Clostridium difficile infection: what works?
    Erik R Dubberke
    Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 31:S38-41. 2010
  6. pmc Impact of clinical symptoms on interpretation of diagnostic assays for Clostridium difficile infections
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, 660 S Euclid, Box 8051, St Louis, MO 63110, USA
    J Clin Microbiol 49:2887-93. 2011
  7. pmc Development and validation of a Clostridium difficile infection risk prediction model
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 32:360-6. 2011
  8. pmc Multicenter study of Clostridium difficile infection rates from 2000 to 2006
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, Box 8051, 660 South Euclid, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 31:1030-7. 2010
  9. pmc Hospital-associated Clostridium difficile infection: is it necessary to track community-onset disease?
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 30:332-7. 2009
  10. pmc Multicenter study of surveillance for hospital-onset Clostridium difficile infection by the use of ICD-9-CM diagnosis codes
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 31:262-8. 2010

Collaborators

Detail Information

Publications40

  1. pmc Burden of Clostridium difficile on the healthcare system
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Clin Infect Dis 55:S88-92. 2012
    ....
  2. doi request reprint Clostridium difficile infection: the scope of the problem
    Erik Dubberke
    Division of Infectious Disease, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Hosp Med 7:S1-4. 2012
    ..The 3 articles that follow in this supplement address the diagnosis and treatment of initial and recurrent CDI, and current practice guidelines for the prevention and control of CDI in the hospital setting...
  3. doi request reprint Strategies for prevention of Clostridium difficile infection
    Erik Dubberke
    Division of Infectious Disease, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Hosp Med 7:S14-7. 2012
    ..difficile, and antibiotic stewardship. Hospitalists, as coordinators of care for each patient and advocates for quality care, can spearhead these efforts...
  4. pmc Implementing automated surveillance for tracking Clostridium difficile infection at multiple healthcare facilities
    Erik R Dubberke
    Washington University School of Medicine, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 33:305-8. 2012
    ..Electronic surveillance was highly sensitive, specific, and showed good to excellent agreement for hospital-onset; community-onset, study facility-associated; indeterminate; and recurrent CDI...
  5. pmc Prevention of healthcare‐associated Clostridium difficile infection: what works?
    Erik R Dubberke
    Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 31:S38-41. 2010
    ..difficile infection. Studies are needed to define the optimal prevention practices and to investigate novel prevention methods...
  6. pmc Impact of clinical symptoms on interpretation of diagnostic assays for Clostridium difficile infections
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, 660 S Euclid, Box 8051, St Louis, MO 63110, USA
    J Clin Microbiol 49:2887-93. 2011
    ..None suffered from any CDI-related adverse events. In conclusion, clinical presentation is important when interpreting C. difficile diagnostic assays...
  7. pmc Development and validation of a Clostridium difficile infection risk prediction model
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 32:360-6. 2011
    ..To develop and validate a risk prediction model that could identify patients at high risk for Clostridium difficile infection (CDI) before they develop disease...
  8. pmc Multicenter study of Clostridium difficile infection rates from 2000 to 2006
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, Box 8051, 660 South Euclid, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 31:1030-7. 2010
    ....
  9. pmc Hospital-associated Clostridium difficile infection: is it necessary to track community-onset disease?
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 30:332-7. 2009
    ....
  10. pmc Multicenter study of surveillance for hospital-onset Clostridium difficile infection by the use of ICD-9-CM diagnosis codes
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 31:262-8. 2010
    ..difficile toxin assay results...
  11. doi request reprint Multicenter study of the impact of community-onset Clostridium difficile infection on surveillance for C. difficile infection
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 30:518-25. 2009
    ..To evaluate the impact of cases of community-onset, healthcare facility (HCF)-associated Clostridium difficile infection (CDI) on the incidence and outbreak detection of CDI...
  12. pmc The impact of ICD-9-CM code rank order on the estimated prevalence of Clostridium difficile infections
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Infect Dis 53:20-5. 2011
    ..Whether ICD-9-CM code rank order affects CDI prevalence estimates is important because the National Hospital Discharge Survey (NHDS) and the Nationwide Inpatient Sample (NIS) have varying limits on the number of ICD-9-CM codes collected...
  13. pmc Identification of a pseudo-outbreak of Clostridium difficile infection (CDI) and the effect of repeated testing, sensitivity, and specificity on perceived prevalence of CDI
    Marina Litvin
    Department of Medicine, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 30:1166-71. 2009
    ..difficile on perceived CDI burden, positive predictive value, and false-positive results...
  14. pmc Attributable outcomes of endemic Clostridium difficile-associated disease in nonsurgical patients
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Emerg Infect Dis 14:1031-8. 2008
    ..Even in a nonoutbreak setting, CDAD had a statistically significant negative impact on patient illness and death, and the impact of CDAD persisted beyond hospital discharge...
  15. pmc A multicenter study of Clostridium difficile infection-related colectomy, 2000-2006
    Amelia M Kasper
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 33:470-6. 2012
    ..To assess Clostridium difficile infection (CDI)-related colectomy rates by CDI surveillance definitions and over time at multiple healthcare facilities...
  16. pmc Recognition and prevention of hospital-associated enteric infections in the intensive care unit
    Linda D Bobo
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Crit Care Med 38:S324-34. 2010
    ..In addition, intensivists should be ready to implement systems changes related to notification, isolation precautions and prevention, and environmental cleaning in the ICU...
  17. pmc Clostridium difficile-associated disease in allogeneic hematopoietic stem-cell transplant recipients: risk associations, protective associations, and outcomes
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Clin Transplant 24:192-8. 2010
    ..6, 95% CI 1.1-6.2). CDAD is a significant cause of morbidity and mortality in allogeneic HSCT patients, but modifiable risk factors exist. Further study is needed to determine the best methods of decreasing patients' risk of CDAD...
  18. doi request reprint Clostridium difficile--associated disease in a setting of endemicity: identification of novel risk factors
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Clin Infect Dis 45:1543-9. 2007
    ..The purpose of this study was to determine risk factors for endemic CDAD, including CDAD pressure, a modified version of colonization pressure...
  19. doi request reprint Short- and long-term attributable costs of Clostridium difficile-associated disease in nonsurgical inpatients
    Erik R Dubberke
    Washington University School of Medicine, Saint Louis, Missouri, USA
    Clin Infect Dis 46:497-504. 2008
    ..There are few data on the short-term and long-term attributable costs of CDAD. The objective of this study was to determine the acute and 180-day attributable inpatient costs of CDAD...
  20. doi request reprint A Clostridium difficile infection "intervention": change in toxin assay results in fewer C difficile infection cases without changes in patient outcomes
    Zhuolin Han
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Am J Infect Control 40:349-53. 2012
    ..The objective of this study was to determine whether the decreased CDI incidence related to the change in EIA resulted in adverse patient outcomes...
  21. doi request reprint Clostridium difficile infection in solid organ transplant recipients
    David J Riddle
    Division of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri 63110, USA
    Curr Opin Organ Transplant 13:592-600. 2008
    ..To provide a general understanding of Clostridium difficile infection with a focus on recent publications that evaluate the disease in solid organ transplant recipients...
  22. ncbi request reprint Evaluation of Clostridium difficile-associated disease pressure as a risk factor for C difficile-associated disease
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Intern Med 167:1092-7. 2007
    ..The purpose of this study was to evaluate CDAD pressure, a modified form of colonization pressure based on symptomatic CDAD cases, as a risk factor for CDAD...
  23. ncbi request reprint Incidence of Clostridium difficile infection in inflammatory bowel disease
    Joseph F Rodemann
    Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Gastroenterol Hepatol 5:339-44. 2007
    ..We sought to determine whether CDAD incidence has increased specifically in hospitalized patients with IBD. We also explored possible differences in the risk for and time to presentation of CDAD between IBD and non-IBD patients...
  24. ncbi request reprint Prevalence of Clostridium difficile environmental contamination and strain variability in multiple health care facilities
    Erik R Dubberke
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Infect Control 35:315-8. 2007
    ..difficile environmental contamination at various health care facilities in a metropolitan area and determine if the North American pulsed field gel electrophoresis type 1 (NAP1) strain was present...
  25. pmc Clostridium difficile in the ICU: the struggle continues
    Linda D Bobo
    Adult Infectious Diseases Division, University School of Medicine, St Louis, MO, USA
    Chest 140:1643-53. 2011
    ....
  26. pmc Use of cytomegalovirus intravenous immune globulin for the adjunctive treatment of cytomegalovirus in hematopoietic stem cell transplant recipients
    Bryan T Alexander
    Department of Pharmacy, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pharmacotherapy 30:554-61. 2010
    ..To describe the characteristics and clinical outcomes of hematopoietic stem cell transplant (HSCT) recipients who received adjunctive cytomegalovirus intravenous immune globulin (CMV-IVIG) for probable or proven CMV disease...
  27. pmc MAPK-activated protein kinase 2 contributes to Clostridium difficile-associated inflammation
    Linda D Bobo
    Departments of Pediatrics, Washington University School of Medicine, StLouis, Missouri, USA
    Infect Immun 81:713-22. 2013
    ..Activation of p38-MK2 in infected animals and humans suggests that this pathway is a key driver of intestinal inflammation in patients with CDI...
  28. pmc Risk factors associated with methicillin-resistant Staphylococcus aureus colonization on hospital admission among oncology patients
    Adam M Schaefer
    Barnes Jewish Hospital, St Louis, MO, USA
    Am J Infect Control 37:603-5. 2009
    ..Risk factors for any S aureus and MRSA colonization on admission in oncology patients are consistent with previous studies in general populations. In addition, recent chemotherapy as a risk factor is a unique finding in this population...
  29. pmc Clostridium difficile infection in the intensive care unit
    David J Riddle
    Division of Infectious Diseases, Departments of Medicine and Pediatrics, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8051, St Louis, MO 63110 1093, USA
    Infect Dis Clin North Am 23:727-43. 2009
    ..This article seeks to provide a broad understanding of CDI in the intensive care unit, with special emphasis on risk factor identification, treatment options, and disease prevention...
  30. doi request reprint A systematic evaluation of methods to optimize culture-based recovery of Clostridium difficile from stool specimens
    Tiffany Hink
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Anaerobe 19:39-43. 2013
    ..Sparks, MD). Identifying the most sensitive method of recovery will allow for further study of asymptomatic C. difficile carriers and their role in the epidemiology of C. difficile...
  31. doi request reprint Review of current literature on the economic burden of Clostridium difficile infection
    Erik R Dubberke
    Infectious Diseases Division, Department of Medicine, Washington University in St Louis, School of Medicine, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 30:57-66. 2009
    ..To more completely assess its economic burden, we performed a review of available literature that reported costs associated with the infection...
  32. ncbi request reprint Severity of Clostridium difficile-associated disease (CDAD) in allogeneic stem cell transplant recipients: evaluation of a CDAD severity grading system
    Erik R Dubberke
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 28:208-11. 2007
    ..Patients with severe CDAD had significantly shorter median survival times and more adverse outcomes than patients with mild or moderate CDAD...
  33. doi request reprint Case-control study of clinical features of influenza in hospitalized patients
    Hilary M Babcock
    Washington University School of Medicine, Infectious Diseases Division, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 29:921-6. 2008
    ..Few data exist on the clinical presentation of influenza in hospitalized patients, which may be distinct from the clinical presentation of influenza in ambulatory patients because of underlying medical conditions and medications...
  34. doi request reprint Micafungin for the prophylaxis and treatment of Candida infections
    Joseph M Fritz
    Washington University School of Medicine, Division of Infectious Diseases, Department of Internal Medicine, 660 South Euclid Avenue, Campus Box 8051, St Louis, MO 63110, USA
    Expert Rev Anti Infect Ther 6:153-62. 2008
    ..In general, micafungin is well tolerated and has favorable safety and drug-interaction profiles...
  35. ncbi request reprint Acute meningoencephalitis caused by adenovirus serotype 26
    Erik R Dubberke
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurovirol 12:235-40. 2006
    ..In this article the authors report a case of adenoviral meningoencephalitis caused by serotype 26 and its identification, not described previously, in cerebrospinal fluid (CSF) by PCR and brain tissue by immunohistochemical staining...
  36. doi request reprint Assessing colectomies due to Clostridium difficile infection: increases in the community, but not in the referral center
    Kathleen M McMullen
    Infection Prevention, Barnes Jewish Hospital, St Louis, MO, USA
    Am J Infect Control 40:778-80. 2012
    ..The investigation found an increase in CDI-related colectomies for CDI not associated with the study institution. Electronically available data facilitated surveillance for severe CDI...
  37. doi request reprint Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in adults with neutropenic fever
    Heather M Arnold
    Department of Pharmacy, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    Pharmacotherapy 29:914-23. 2009
    ....
  38. pmc Development and evaluation of a novel, semiautomated Clostridium difficile typing platform
    Lars F Westblade
    Department of Pathology and Immunology, Washington University School of Medicine in St Louis, St Louis, Missouri, USA
    J Clin Microbiol 51:621-4. 2013
    ..The platform is reproducible with minimal intra- or interassay variability. This method exhibited a discriminatory index of 0.954 and is therefore comparable to more arduous typing systems, such as pulsed-field gel electrophoresis...
  39. pmc ICD-9 codes and surveillance for Clostridium difficile-associated disease
    Erik R Dubberke
    Washington University in St Louis School of Medicine, Saint Louis, Missouri, USA
    Emerg Infect Dis 12:1576-9. 2006
    ..The correlation between toxin assay results and ICD-9 codes was good (K = 0.72, p<0.01). The sensitivity of the ICD-9 codes was 78% and the specificity was 99.7%...
  40. ncbi request reprint A woman from Honduras with a painful forearm and fever
    Erik R Dubberke
    Infectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Trop Med Hyg 78:697-8. 2008