Joseph D Dougherty
Affiliation: Washington University School of Medicine
- The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviorsJoseph D Dougherty
Department of Genetics and Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Neurosci 33:2732-53. 2013..This work provides a reproducible and accurate method to profile serotonergic neurons under a variety of conditions and suggests a novel paradigm for gaining information on the etiology of psychiatric disorders...
- Mouse transgenesis in a single locus with independent regulation for multiple fluorophoresJoseph D Dougherty
Laboratory of Molecular Biology, The Rockefeller University, New York, New York, United States of America
PLoS ONE 7:e40511. 2012..This generic solution should permit more sophisticated experimental manipulations to assess functional interactions amongst populations of cell types in vivo in a more rapid and efficient manner...
- Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulationJasbir Dalal
Department of Genetics, Washington University School of Medicine, St Louis, MO 63110, USA
Genes Dev 27:565-78. 2013..These data provide an in-depth and accurate profile of Hcrt neuron gene expression and suggest that Lhx9 may be important for specification or survival of a subset of these cells...
- Analytical approaches to RNA profiling data for the identification of genes enriched in specific cellsJoseph D Dougherty
Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
Nucleic Acids Res 38:4218-30. 2010..We apply this measure to a large survey of CNS cell-specific microarray data to identify those genes that are significantly enriched in each population Data and algorithms are available online (www.bactrap.org)...