Joseph D Dougherty

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors
    Joseph D Dougherty
    Department of Genetics and Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 33:2732-53. 2013
  2. pmc Mouse transgenesis in a single locus with independent regulation for multiple fluorophores
    Joseph D Dougherty
    Laboratory of Molecular Biology, The Rockefeller University, New York, New York, United States of America
    PLoS ONE 7:e40511. 2012
  3. doi request reprint Identifying essential cell types and circuits in autism spectrum disorders
    Susan E Maloney
    Department of Genetics, Washington University School of Medicine, St Louis, Missouri, USA Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Int Rev Neurobiol 113:61-96. 2013
  4. pmc Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation
    Jasbir Dalal
    Department of Genetics, Washington University School of Medicine, St Louis, MO 63110, USA
    Genes Dev 27:565-78. 2013
  5. doi request reprint Investigation of maternal genotype effects in autism by genome-wide association
    Han Yuan
    Department of Genetics, Washington University School of Medicine, St Louis, Missouri, USA
    Autism Res 7:245-53. 2014
  6. doi request reprint Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders
    Xiaoxiao Xu
    Preston M Green Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Missouri 63130, and Departments of Genetics and Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri 63110
    J Neurosci 34:1420-31. 2014
  7. pmc Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells
    Joseph D Dougherty
    Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
    Nucleic Acids Res 38:4218-30. 2010

Collaborators

Detail Information

Publications7

  1. pmc The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors
    Joseph D Dougherty
    Department of Genetics and Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 33:2732-53. 2013
    ..This work provides a reproducible and accurate method to profile serotonergic neurons under a variety of conditions and suggests a novel paradigm for gaining information on the etiology of psychiatric disorders...
  2. pmc Mouse transgenesis in a single locus with independent regulation for multiple fluorophores
    Joseph D Dougherty
    Laboratory of Molecular Biology, The Rockefeller University, New York, New York, United States of America
    PLoS ONE 7:e40511. 2012
    ..This generic solution should permit more sophisticated experimental manipulations to assess functional interactions amongst populations of cell types in vivo in a more rapid and efficient manner...
  3. doi request reprint Identifying essential cell types and circuits in autism spectrum disorders
    Susan E Maloney
    Department of Genetics, Washington University School of Medicine, St Louis, Missouri, USA Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Int Rev Neurobiol 113:61-96. 2013
    ..We hope that in the future, systematic studies of cellular sufficiency and genetic interaction will help to classify patients into groups by type of cellular disruptions which suggest tractable therapeutic targets. ..
  4. pmc Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation
    Jasbir Dalal
    Department of Genetics, Washington University School of Medicine, St Louis, MO 63110, USA
    Genes Dev 27:565-78. 2013
    ..These data provide an in-depth and accurate profile of Hcrt neuron gene expression and suggest that Lhx9 may be important for specification or survival of a subset of these cells...
  5. doi request reprint Investigation of maternal genotype effects in autism by genome-wide association
    Han Yuan
    Department of Genetics, Washington University School of Medicine, St Louis, Missouri, USA
    Autism Res 7:245-53. 2014
    ..However, there was evidence for the possibility of a large number of alleles of effective size marginally below our power to detect. Autism Res 2014, 7: 245-253. © 2014 International Society for Autism Research, Wiley Periodicals, Inc. ..
  6. doi request reprint Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders
    Xiaoxiao Xu
    Preston M Green Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Missouri 63130, and Departments of Genetics and Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri 63110
    J Neurosci 34:1420-31. 2014
    ..Our approach may be useful for identifying common cellular mechanisms arising from distinct genetic lesions. ..
  7. pmc Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells
    Joseph D Dougherty
    Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
    Nucleic Acids Res 38:4218-30. 2010
    ..We apply this measure to a large survey of CNS cell-specific microarray data to identify those genes that are significantly enriched in each population Data and algorithms are available online (www.bactrap.org)...