Research Topics
Species | L P DehnerSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Publications
Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associationsLouis P Dehner
Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
Mod Pathol 25:602-14. 2012..Our study suggests that cervical embryonal rhabdomyosarcoma may be another pathological manifestation in the spectrum of extrapulmonary pathology in the setting of pleuropulmonary blastoma...
Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestationsLouis P Dehner
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, Missouri, 63110, USA
Am J Surg Pathol 27:579-93. 2003....- Adrenal cortical neoplasms in children: why so many carcinomas and yet so many survivors?Louis P Dehner
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
Pediatr Dev Pathol 12:284-91. 2009..A risk assessment system is proposed that incorporates tumor weight, localization of tumor to the gland without invasion into the surrounding tissues or organs, and absence of metastasis... - The medical autopsy: past, present, and dubious futureLouis P Dehner
Department of Pathology and Immunology of Washington University School of Medicine, St Louis, USA
Mo Med 107:94-100. 2010..Will the autopsy survive? There are many reasons to advocate for the autopsy and they are considered in this discussion. The reasons to perform an autopsy remain as pertinent and relevant today as they did 50 to 100 years ago... - The evolution of the diagnosis and understanding of primitive and embryonic neoplasms in children: living through an epochL P Dehner
Lauren V Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, Barnes Jewish and St Louis Children s Hospitals, Missouri, USA
Mod Pathol 11:669-85. 1998.... - A role for fluorescence in situ hybridization detection of chromosome 22q dosage in distinguishing atypical teratoid/rhabdoid tumors from medulloblastoma/central primitive neuroectodermal tumorsL A Bruch
Department of Pathology (Neuropathology) and Anatomic Pathology, Washington University School of Medicine, St Louis, MO 63110, USA
Hum Pathol 32:156-62. 2001.... - CRTC1 rearrangements in the absence of t(11;19) in primary cutaneous mucoepidermoid carcinomaJ K M Lennerz
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
Br J Dermatol 161:925-9. 2009..The latter has been shown to harbour an oncogenic translocation resulting in a fusion gene consisting of exon 1 of CRTC1/MECT1/TORC1 at 19p and exons 2-5 of MAML2 at 11q... - Visceral primitive peripheral neuroectodermal tumors: a clinicopathologic and molecular studyE J Perlman
Lauren V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St Louis, MO 63110, USA
Hum Pathol 32:1109-15. 2001..05, chi(2) test). These results firmly establish the genetic relationship between EWS/PNET of visceral sites, soft tissue, and bone... - Germ cell tumors of the mediastinumL P Dehner
Department of Pathology, Washington University Medical Center, St Louis, MO 63110
Semin Diagn Pathol 7:266-84. 1990..It should be remembered that mediastinal lymph nodes are metastatic sites for primary gonadal germ cell tumors, so that a thorough clinical evaluation is necessary to exclude the latter possibility... - Chromosome 22q dosage in composite extrarenal rhabdoid tumors: clonal evolution or a phenotypic mimic?C E Fuller
Division of Neuropathology, Department of Pathology and Immunology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
Hum Pathol 32:1102-8. 2001.... - Undifferentiated embryonal sarcoma with unusual features arising within mesenchymal hamartoma of the liver: report of a case and review of the literatureP E Swanson
L. V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St. Louis, MO 63110, USA
Pediatr Dev Pathol 4:482-9. 2001..We report a case of UES arising in a young boy with MHL, with unusual histologic features, including large mesothelial-lined cysts and ectopic adrenal cortical tissue under Glisson's capsule... - Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical studyJ R Cook
Lauren V. Ackerman Division of Surgical Pathology, Washington University School of Medicine, St. Louis, Missouri, USA
Am J Surg Pathol 25:1364-71. 2001.... - Beware of "degenerating" congenital pulmonary cystsLouis P Dehner
Pediatr Surg Int 21:123-4. 2005 - Viral diseases of the liver in children: diagnostic and differential diagnostic considerationsFrances V White
Department of Pathology and Immunology, Lauren V Ackerman Laboratory of Surgical Pathology, St Louis Children s Hospital at the Washington University Medical Center, 660 South Euclid Avenue, St Louis, MO 63110, USA
Pediatr Dev Pathol 7:552-67. 2004..The main epidemiologic, clinical, and pathologic features of the hepatotropic viruses are discussed, with an emphasis on pediatric studies and the differential diagnosis of hepatitis in childhood... - INI1 expression is retained in composite rhabdoid tumors, including rhabdoid meningiomasArie Perry
Department of Pathology, Washington University School of Medicine, St Louis, MO 63001 1093, USA
Mod Pathol 18:951-8. 2005..Therefore, we conclude that INI1 immunohistochemistry is a relatively simple, sensitive, and specific technique for distinguishing malignant rhabdoid tumor and atypical teratoid/rhabdoid tumor from composite rhabdoid tumor... - Urothelial neoplasms in patients 20 years or younger: a clinicopathological analysis using the world health organization 2004 bladder consensus classificationSamson W Fine
Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA
J Urol 174:1976-80. 2005..Thus, the diagnostic category of PUNLMP allowed 43.5% of patients in this series to avoid being labeled with "cancer" at a young age... - Molecular diagnosis of Ewing sarcoma/primitive neuroectodermal tumor in routinely processed tissue: a comparison of two FISH strategies and RT-PCR in malignant round cell tumorsRobert S Bridge
Department of Pathology and Immunology, Lauren V Ackerman Laboratory of Surgical Pathology, Barnes-Jewish Hospital, Washington University Medical Center, St Louis, MO 63110-1093, USA
Mod Pathol 19:1-8. 2006..The commercial break apart probe set is both readily available and easy to interpret, making it particularly attractive. Nonetheless, complex round cell tumors often benefit from molecular testing with multiple methods... - Correction: Pleuropulmonary blastoma, not rhabdomyosarcoma in a congenital lung cystShyun Pai
Department of Pathology, Kaohsiung Medical Center, Chang Gung University and Memorial Hospital, Niao-Sung, Kaohsiung, Taiwan
Pediatr Blood Cancer 48:370-1. 2007 - Primary peritoneal epithelioid hemangioendotheliomaLorena Posligua
Lauren V. Ackerman Laboratory of Surgical Pathology, Barnes-Jewish Hospital, Washington University Medical Center, St. Louis, Missouri, USA
Int J Surg Pathol 14:257-67. 2006..This series identifies the characteristics of peritoneal epithelioid hemangioendothelioma that can be reliably used for diagnosis... - Type I pleuropulmonary blastoma: pathology and biology study of 51 cases from the international pleuropulmonary blastoma registryDana Ashley Hill
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
Am J Surg Pathol 32:282-95. 2008..In the meantime, recognition of this lesion as a neoplasm with malignant potential rather than a developmental cystic malformation is vital so the child can receive complete excision and appropriate follow-up care... - Type I pleuropulmonary blastoma: a report from the International Pleuropulmonary Blastoma RegistryJohn R Priest
International Pleuropulmonary Blastoma Registry, Children s Hospitals and Clinics of Minnesota, St Paul, Minnesota 55102, USA
J Clin Oncol 24:4492-8. 2006..This article describes the first collection of type I PPB cases, analyzes outcome based on treatments of surgery or surgery plus chemotherapy, and presents type I PPB management recommendations... - Desmoplastic nested spindle cell tumor of liver: report of four cases of a proposed new entityD Ashley Hill
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, St Louis, MO 63110, USA
Am J Surg Pathol 29:1-9. 2005..5 years, 7 years, 5 years, and 8 months post-surgery. The morphologic appearance and immunohistochemical profile of these lesions are unique in our experience and represent a new category of pediatric liver tumor... - Mesenchymal hamartoma of the liver in the adult: association with distinct clinical features and histological changesJames R Cook
Lauren V. Ackerman Laboratory of Surgical Pathology, Barnes-Jewish and St. Louis Children's Hospitals, Washington University Medical Center, St. Louis, MO, USA
Hum Pathol 33:893-8. 2002..Recognition of the clinicopathologic differences between adult and pediatric cases will facilitate accurate diagnosis of this uncommon lesion... - Meningeal tumors of childhood and infancy. An update and literature reviewArie Perry
Division of Neuropathology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
Brain Pathol 13:386-408. 2003..As in other areas of pediatric pathology, there are significant differences between this patient cohort and adults, differences which will be emphasized in this review... - Columnar cell variant of papillary thyroid carcinoma. Report of a case with cytologic findingsLourdes R Ylagan
Lauren V. Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Barnes and Jewish Hospital, Washington University Medical Center, St. Louis, Missouri, USA
Acta Cytol 48:73-7. 2004..Immunohistochemical staining to rule out other thyroid neoplasms can be performed to aid in the diagnosis... - Low-grade fibrosarcoma (hyalinizing spindle cell tumor with giant rosettes) with pulmonary metastases at presentation: case report and review of the literatureKarim E Sirgi
Pathology Department, University of Edinburgh Medical School, Edinburgh, Scotland
Int J Surg Pathol 10:211-6. 2002..The fact should not be overlooked that the HSCT is a recently reported entity whose natural history and nosology are subjects of continuing observation, study, and discussion... - Fine needle aspiration of the thyroid: a cytohistologic correlation and study of discrepant casesLourdes R Ylagan
The Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, Missouri 63108, USA
Thyroid 14:35-41. 2004..The purpose of this study was to evaluate the causes for discordance between the interpretation on FNA and the pathologic findings in the resected thyroid... - Fine-needle aspiration cytology of recurrent granulosa cell tumor: case report with differential diagnosis and immunocytochemistryLourdes R Ylagan
Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, Missouri 63110, USA
Diagn Cytopathol 27:38-41. 2002..The cytopathologic features of metastatic granular cell tumor have been described in a limited number of previous reports... - Abdominal mucinous cystic neoplasm in a male childJean J Luo
The Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO, USA
Pediatr Dev Pathol 11:46-9. 2008..Only 1 other case of a mesenteric MCN has been reported to date in a child and none in a male. The MCN of the mesentery joins other, somewhat more common cystic lesions of the omentum and mesentery presenting in childhood... - Rosai-Dorfman disease following bone marrow transplantation for pre-B cell acute lymphoblastic leukemiaS Ambati
Department of Pediatrics, Miami Children s Hospital, Miami, Florida 33155, USA
Pediatr Blood Cancer 51:433-5. 2008..Only one previous example of acute lymphoblastic leukemia in childhood has been reported with R-D disease... - Practical application of molecular genetic testing as an aid to the surgical pathologic diagnosis of sarcomas: a prospective studyD Ashley Hill
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, MO, USA
Am J Surg Pathol 26:965-77. 2002..We conclude that PCR-based testing is a useful adjunct for the diagnosis of malignant small round cell tumors, spindle cell tumors, and other miscellaneous neoplasms in routine surgical pathology practice... - [Urothelial neoplasms in individuals younger than 20 years show very few genetic alterations and have a favourable clinical outcome]Johannes Giedl
, , Regensburg
Verh Dtsch Ges Pathol 90:253-63. 2006..The most frequent genetic alterations found in elderly patients are extremely rare. Urothelial neoplasms in young patients could represent a biologically distinct form of bladder disease with lack of genetic instability in most cases... - Transcripts, transcripts, everywhereLouis P Dehner
Adv Anat Pathol 9:265-6; author reply 266-7. 2002 - Median raphe cyst in the scrotum after orchiopexyLouis P Dehner
Int J Urol 14:573-4; author reply 574. 2007 - Cytologic diagnosis of Ewing sarcoma/peripheral neuroectodermal tumor with paired prospective molecular genetic analysisSouzan Sanati
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and Saint Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110 1093, USA
Cancer 111:192-9. 2007.... - Primary cardiac alveolar soft part sarcoma. A report of the first observed case with molecular diagnostics corroborationJean Luo
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO, USA
Pediatr Dev Pathol 11:142-7. 2008..This initial case of primary cardiac ASPS joins the list of other types of sarcomas in children that have been reported as primary neoplasms of the heart... - Vinblastine and methotrexate for desmoid fibromatosis in children: results of a Pediatric Oncology Group Phase II TrialStephen X Skapek
Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
J Clin Oncol 25:501-6. 2007..To determine the efficacy and safety of using vinblastine (Vbl) and methotrexate (Mtx) in children with desmoid-type fibromatosis that is recurrent or not amenable to treatment with radiation or surgery... - Pleomorphic rhabdomyosarcoma of the anterior abdominal wall following multimodality treatment for carcinoma of the rectumVeena Rajaram
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA
Int J Surg Pathol 12:161-5. 2004..We report a case of pleomorphic rhabdomyosarcoma of the anterior abdominal wall following treatment of rectal carcinoma, and we review the literature... - The challenges of vasoformative tumors of the liver in childrenLouis P Dehner
Pediatr Dev Pathol 7:A5-7. 2004 - A cautionary note about congenital cystic adenomatoid malformation (CCAM) type 4D Ashley Hill
Am J Surg Pathol 28:554-5; author reply 555. 2004 - Reawakening to the existence of juvenile xanthogranulomaLouis P Dehner
Am J Surg Pathol 29:119-20. 2005 - Mucoepidermoid carcinoma of the skin: a distinct entity from adenosquamous carcinoma: a case study with a review of the literatureWolfram F J Riedlinger
Lauren V. Ackerman Laboratory of Surgical Pathology, Barnes-Jewish Hospital, Washington University Medical Center, St. Louis, MO 63110-1093, USA
Am J Surg Pathol 29:131-5. 2005..Additionally, the immunophenotype of our case is similar to at least two other cases of cutaneous MEC, as well as MEC of the salivary gland, to support the hypothesis that this neoplasm is adnexal rather than epidermal in origin... - Concurrent infantile hemangioendothelioma and mesenchymal hamartoma in a developmentally arrested liver of an infant requiring hepatic transplantationPablo A Bejarano
Department of Pathology, University of Miami School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz Center Room 2042, Miami, FL 33136, USA
Pediatr Dev Pathol 6:552-7. 2003..This simultaneous involvement of the liver by a mesenchymal hamartoma and infantile hemangioendothelioma is unique. A review of the literature revealed only one incompletely characterized case with similar findings... - Congenital malignant rhabdoid tumorLouis P Dehner
Diagn Cytopathol 32:135-6. 2005 - Paraganglioma of the vagina: report of a case, including immunohistochemical and ultrastructural findingsAnjum Hassan
Mallinckrodt Institute of Radiology, Washington University Medical Center, St. Louis, MO 63110, USA
Int J Gynecol Pathol 22:404-6. 2003..The clinical course after the biopsy implied that this neoplasm had been awakened from its functionless dormancy... - Dermatofibrosarcoma protuberans of the vulva and groin: detection of COL1A1-PDGFB fusion transcripts by RT-PCRNeriman Gokden
Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, MO, USA
J Cutan Pathol 30:190-5. 2003..The trunk and extremities are the anatomic sites of predilection for DFSP, whereas the vulva and groin are quite uncommon sites of involvement... - Successful treatment of inflammatory myofibroblastic tumor with malignant transformation by surgical resection and chemotherapyMegan K Dishop
Department of Pathology, University of Kentuckey Children's Hospital/Chandler Medical Center, Lexington, USA
J Pediatr Hematol Oncol 25:153-8. 2003..He is disease-free after 2 years, representing successful combined surgery and chemotherapy in the treatment of malignant IMT. The use of chemotherapy for aggressive myofibroblastic tumors is reviewed... - Perianal rhabdomyosarcoma presenting as a perirectal abscess: A report of 11 casesD Ashley Hill
Department of Pathology, St Jude Children's Research Hospital and University of Tennessee, Memphis TN, USA
J Pediatr Surg 37:576-81. 2002....