L P Dehner

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint The evolution of the diagnosis and understanding of primitive and embryonic neoplasms in children: living through an epoch
    L P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, Barnes Jewish and St Louis Children s Hospitals, Missouri, USA
    Mod Pathol 11:669-85. 1998
  2. ncbi request reprint Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations
    Louis P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, Missouri, 63110, USA
    Am J Surg Pathol 27:579-93. 2003
  3. doi request reprint Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations
    Louis P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Mod Pathol 25:602-14. 2012
  4. doi request reprint Adrenal cortical neoplasms in children: why so many carcinomas and yet so many survivors?
    Louis P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Pediatr Dev Pathol 12:284-91. 2009
  5. ncbi request reprint The medical autopsy: past, present, and dubious future
    Louis P Dehner
    Department of Pathology and Immunology of Washington University School of Medicine, St Louis, USA
    Mo Med 107:94-100. 2010
  6. ncbi request reprint A role for fluorescence in situ hybridization detection of chromosome 22q dosage in distinguishing atypical teratoid/rhabdoid tumors from medulloblastoma/central primitive neuroectodermal tumors
    L A Bruch
    Department of Pathology (Neuropathology) and Anatomic Pathology, Washington University School of Medicine, St Louis, MO 63110, USA
    Hum Pathol 32:156-62. 2001
  7. doi request reprint CRTC1 rearrangements in the absence of t(11;19) in primary cutaneous mucoepidermoid carcinoma
    J K M Lennerz
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Br J Dermatol 161:925-9. 2009
  8. ncbi request reprint Visceral primitive peripheral neuroectodermal tumors: a clinicopathologic and molecular study
    E J Perlman
    Lauren V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St Louis, MO 63110, USA
    Hum Pathol 32:1109-15. 2001
  9. ncbi request reprint Germ cell tumors of the mediastinum
    L P Dehner
    Department of Pathology, Washington University Medical Center, St Louis, MO 63110
    Semin Diagn Pathol 7:266-84. 1990
  10. ncbi request reprint Chromosome 22q dosage in composite extrarenal rhabdoid tumors: clonal evolution or a phenotypic mimic?
    C E Fuller
    Division of Neuropathology, Department of Pathology and Immunology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Hum Pathol 32:1102-8. 2001

Collaborators

Detail Information

Publications48

  1. ncbi request reprint The evolution of the diagnosis and understanding of primitive and embryonic neoplasms in children: living through an epoch
    L P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, Barnes Jewish and St Louis Children s Hospitals, Missouri, USA
    Mod Pathol 11:669-85. 1998
    ....
  2. ncbi request reprint Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations
    Louis P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, Missouri, 63110, USA
    Am J Surg Pathol 27:579-93. 2003
    ....
  3. doi request reprint Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations
    Louis P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Mod Pathol 25:602-14. 2012
    ..Our study suggests that cervical embryonal rhabdomyosarcoma may be another pathological manifestation in the spectrum of extrapulmonary pathology in the setting of pleuropulmonary blastoma...
  4. doi request reprint Adrenal cortical neoplasms in children: why so many carcinomas and yet so many survivors?
    Louis P Dehner
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Pediatr Dev Pathol 12:284-91. 2009
    ..A risk assessment system is proposed that incorporates tumor weight, localization of tumor to the gland without invasion into the surrounding tissues or organs, and absence of metastasis...
  5. ncbi request reprint The medical autopsy: past, present, and dubious future
    Louis P Dehner
    Department of Pathology and Immunology of Washington University School of Medicine, St Louis, USA
    Mo Med 107:94-100. 2010
    ..Will the autopsy survive? There are many reasons to advocate for the autopsy and they are considered in this discussion. The reasons to perform an autopsy remain as pertinent and relevant today as they did 50 to 100 years ago...
  6. ncbi request reprint A role for fluorescence in situ hybridization detection of chromosome 22q dosage in distinguishing atypical teratoid/rhabdoid tumors from medulloblastoma/central primitive neuroectodermal tumors
    L A Bruch
    Department of Pathology (Neuropathology) and Anatomic Pathology, Washington University School of Medicine, St Louis, MO 63110, USA
    Hum Pathol 32:156-62. 2001
    ....
  7. doi request reprint CRTC1 rearrangements in the absence of t(11;19) in primary cutaneous mucoepidermoid carcinoma
    J K M Lennerz
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Br J Dermatol 161:925-9. 2009
    ..The latter has been shown to harbour an oncogenic translocation resulting in a fusion gene consisting of exon 1 of CRTC1/MECT1/TORC1 at 19p and exons 2-5 of MAML2 at 11q...
  8. ncbi request reprint Visceral primitive peripheral neuroectodermal tumors: a clinicopathologic and molecular study
    E J Perlman
    Lauren V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St Louis, MO 63110, USA
    Hum Pathol 32:1109-15. 2001
    ..05, chi(2) test). These results firmly establish the genetic relationship between EWS/PNET of visceral sites, soft tissue, and bone...
  9. ncbi request reprint Germ cell tumors of the mediastinum
    L P Dehner
    Department of Pathology, Washington University Medical Center, St Louis, MO 63110
    Semin Diagn Pathol 7:266-84. 1990
    ..It should be remembered that mediastinal lymph nodes are metastatic sites for primary gonadal germ cell tumors, so that a thorough clinical evaluation is necessary to exclude the latter possibility...
  10. ncbi request reprint Chromosome 22q dosage in composite extrarenal rhabdoid tumors: clonal evolution or a phenotypic mimic?
    C E Fuller
    Division of Neuropathology, Department of Pathology and Immunology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Hum Pathol 32:1102-8. 2001
    ....
  11. ncbi request reprint Undifferentiated embryonal sarcoma with unusual features arising within mesenchymal hamartoma of the liver: report of a case and review of the literature
    P E Swanson
    L. V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St. Louis, MO 63110, USA
    Pediatr Dev Pathol 4:482-9. 2001
    ..We report a case of UES arising in a young boy with MHL, with unusual histologic features, including large mesothelial-lined cysts and ectopic adrenal cortical tissue under Glisson's capsule...
  12. ncbi request reprint Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study
    J R Cook
    Lauren V. Ackerman Division of Surgical Pathology, Washington University School of Medicine, St. Louis, Missouri, USA
    Am J Surg Pathol 25:1364-71. 2001
    ....
  13. ncbi request reprint Beware of "degenerating" congenital pulmonary cysts
    Louis P Dehner
    Pediatr Surg Int 21:123-4. 2005
  14. ncbi request reprint Viral diseases of the liver in children: diagnostic and differential diagnostic considerations
    Frances V White
    Department of Pathology and Immunology, Lauren V Ackerman Laboratory of Surgical Pathology, St Louis Children s Hospital at the Washington University Medical Center, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Pediatr Dev Pathol 7:552-67. 2004
    ..The main epidemiologic, clinical, and pathologic features of the hepatotropic viruses are discussed, with an emphasis on pediatric studies and the differential diagnosis of hepatitis in childhood...
  15. ncbi request reprint INI1 expression is retained in composite rhabdoid tumors, including rhabdoid meningiomas
    Arie Perry
    Department of Pathology, Washington University School of Medicine, St Louis, MO 63001 1093, USA
    Mod Pathol 18:951-8. 2005
    ..Therefore, we conclude that INI1 immunohistochemistry is a relatively simple, sensitive, and specific technique for distinguishing malignant rhabdoid tumor and atypical teratoid/rhabdoid tumor from composite rhabdoid tumor...
  16. ncbi request reprint Urothelial neoplasms in patients 20 years or younger: a clinicopathological analysis using the world health organization 2004 bladder consensus classification
    Samson W Fine
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Urol 174:1976-80. 2005
    ..Urothelial neoplasms in patients younger than 20 years are rare, with conflicting data regarding clinical outcomes...
  17. ncbi request reprint Molecular diagnosis of Ewing sarcoma/primitive neuroectodermal tumor in routinely processed tissue: a comparison of two FISH strategies and RT-PCR in malignant round cell tumors
    Robert S Bridge
    Department of Pathology and Immunology, Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, MO 63110 1093, USA
    Mod Pathol 19:1-8. 2006
    ..The commercial break apart probe set is both readily available and easy to interpret, making it particularly attractive. Nonetheless, complex round cell tumors often benefit from molecular testing with multiple methods...
  18. ncbi request reprint Correction: Pleuropulmonary blastoma, not rhabdomyosarcoma in a congenital lung cyst
    Shyun Pai
    Department of Pathology, Kaohsiung Medical Center, Chang Gung University and Memorial Hospital, Niao Sung, Kaohsiung, Taiwan
    Pediatr Blood Cancer 48:370-1. 2007
  19. ncbi request reprint Primary peritoneal epithelioid hemangioendothelioma
    Lorena Posligua
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, Missouri, USA
    Int J Surg Pathol 14:257-67. 2006
    ..This series identifies the characteristics of peritoneal epithelioid hemangioendothelioma that can be reliably used for diagnosis...
  20. doi request reprint Type I pleuropulmonary blastoma: pathology and biology study of 51 cases from the international pleuropulmonary blastoma registry
    Dana Ashley Hill
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110, USA
    Am J Surg Pathol 32:282-95. 2008
    ..In the meantime, recognition of this lesion as a neoplasm with malignant potential rather than a developmental cystic malformation is vital so the child can receive complete excision and appropriate follow-up care...
  21. ncbi request reprint Type I pleuropulmonary blastoma: a report from the International Pleuropulmonary Blastoma Registry
    John R Priest
    International Pleuropulmonary Blastoma Registry, Children s Hospitals and Clinics of Minnesota, St Paul, Minnesota 55102, USA
    J Clin Oncol 24:4492-8. 2006
    ..This article describes the first collection of type I PPB cases, analyzes outcome based on treatments of surgery or surgery plus chemotherapy, and presents type I PPB management recommendations...
  22. ncbi request reprint Desmoplastic nested spindle cell tumor of liver: report of four cases of a proposed new entity
    D Ashley Hill
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, St Louis, MO 63110, USA
    Am J Surg Pathol 29:1-9. 2005
    ..5 years, 7 years, 5 years, and 8 months post-surgery. The morphologic appearance and immunohistochemical profile of these lesions are unique in our experience and represent a new category of pediatric liver tumor...
  23. ncbi request reprint Mesenchymal hamartoma of the liver in the adult: association with distinct clinical features and histological changes
    James R Cook
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO, USA
    Hum Pathol 33:893-8. 2002
    ..Recognition of the clinicopathologic differences between adult and pediatric cases will facilitate accurate diagnosis of this uncommon lesion...
  24. ncbi request reprint Meningeal tumors of childhood and infancy. An update and literature review
    Arie Perry
    Division of Neuropathology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Brain Pathol 13:386-408. 2003
    ..As in other areas of pediatric pathology, there are significant differences between this patient cohort and adults, differences which will be emphasized in this review...
  25. ncbi request reprint Columnar cell variant of papillary thyroid carcinoma. Report of a case with cytologic findings
    Lourdes R Ylagan
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Barnes and Jewish Hospital, Washington University Medical Center, St Louis, Missouri, USA
    Acta Cytol 48:73-7. 2004
    ..We present a case of the columnar cell variant of PTC in a young woman that demonstrates the diagnostic challenge...
  26. ncbi request reprint Low-grade fibrosarcoma (hyalinizing spindle cell tumor with giant rosettes) with pulmonary metastases at presentation: case report and review of the literature
    Maureen J O'Sullivan
    Pathology Department, University of Edinburgh Medical School, Edinburgh, Scotland
    Int J Surg Pathol 10:211-6. 2002
    ..The fact should not be overlooked that the HSCT is a recently reported entity whose natural history and nosology are subjects of continuing observation, study, and discussion...
  27. ncbi request reprint Fine needle aspiration of the thyroid: a cytohistologic correlation and study of discrepant cases
    Lourdes R Ylagan
    The Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, Missouri 63108, USA
    Thyroid 14:35-41. 2004
    ..The purpose of this study was to evaluate the causes for discordance between the interpretation on FNA and the pathologic findings in the resected thyroid...
  28. ncbi request reprint Fine-needle aspiration cytology of recurrent granulosa cell tumor: case report with differential diagnosis and immunocytochemistry
    Lourdes R Ylagan
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University Medical Center, St Louis, Missouri 63110, USA
    Diagn Cytopathol 27:38-41. 2002
    ..The cytopathologic features of metastatic granular cell tumor have been described in a limited number of previous reports...
  29. doi request reprint Abdominal mucinous cystic neoplasm in a male child
    Jean J Luo
    The Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO, USA
    Pediatr Dev Pathol 11:46-9. 2008
    ..Only 1 other case of a mesenteric MCN has been reported to date in a child and none in a male. The MCN of the mesentery joins other, somewhat more common cystic lesions of the omentum and mesentery presenting in childhood...
  30. doi request reprint Rosai-Dorfman disease following bone marrow transplantation for pre-B cell acute lymphoblastic leukemia
    S Ambati
    Department of Pediatrics, Miami Children s Hospital, Miami, Florida 33155, USA
    Pediatr Blood Cancer 51:433-5. 2008
    ..Only one previous example of acute lymphoblastic leukemia in childhood has been reported with R-D disease...
  31. ncbi request reprint Practical application of molecular genetic testing as an aid to the surgical pathologic diagnosis of sarcomas: a prospective study
    D Ashley Hill
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, MO, USA
    Am J Surg Pathol 26:965-77. 2002
    ..We conclude that PCR-based testing is a useful adjunct for the diagnosis of malignant small round cell tumors, spindle cell tumors, and other miscellaneous neoplasms in routine surgical pathology practice...
  32. ncbi request reprint [Urothelial neoplasms in individuals younger than 20 years show very few genetic alterations and have a favourable clinical outcome]
    Johannes Giedl
    Institut fur Pathologie, Universitat Regensburg, Regensburg
    Verh Dtsch Ges Pathol 90:253-63. 2006
    ..Urothelial neoplasms in patients 19 years or younger are rare, with conflicting data regarding clinical outcome and no molecular data available...
  33. ncbi request reprint Transcripts, transcripts, everywhere
    Maureen J O'Sullivan
    Adv Anat Pathol 9:265-6; author reply 266-7. 2002
  34. ncbi request reprint Median raphe cyst in the scrotum after orchiopexy
    Louis P Dehner
    Int J Urol 14:573-4; author reply 574. 2007
  35. ncbi request reprint Cytologic diagnosis of Ewing sarcoma/peripheral neuroectodermal tumor with paired prospective molecular genetic analysis
    Souzan Sanati
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and Saint Louis Children s Hospitals, Washington University Medical Center, St Louis, MO 63110 1093, USA
    Cancer 111:192-9. 2007
    ....
  36. ncbi request reprint Primary cardiac alveolar soft part sarcoma. A report of the first observed case with molecular diagnostics corroboration
    Jean Luo
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish and St Louis Children s Hospitals, Washington University Medical Center, St Louis, MO, USA
    Pediatr Dev Pathol 11:142-7. 2008
    ..This initial case of primary cardiac ASPS joins the list of other types of sarcomas in children that have been reported as primary neoplasms of the heart...
  37. ncbi request reprint Vinblastine and methotrexate for desmoid fibromatosis in children: results of a Pediatric Oncology Group Phase II Trial
    Stephen X Skapek
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Clin Oncol 25:501-6. 2007
    ..To determine the efficacy and safety of using vinblastine (Vbl) and methotrexate (Mtx) in children with desmoid-type fibromatosis that is recurrent or not amenable to treatment with radiation or surgery...
  38. ncbi request reprint Pleomorphic rhabdomyosarcoma of the anterior abdominal wall following multimodality treatment for carcinoma of the rectum
    Veena Rajaram
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Int J Surg Pathol 12:161-5. 2004
    ..We report a case of pleomorphic rhabdomyosarcoma of the anterior abdominal wall following treatment of rectal carcinoma, and we review the literature...
  39. ncbi request reprint The challenges of vasoformative tumors of the liver in children
    Louis P Dehner
    Pediatr Dev Pathol 7:A5-7. 2004
  40. ncbi request reprint A cautionary note about congenital cystic adenomatoid malformation (CCAM) type 4
    D Ashley Hill
    Am J Surg Pathol 28:554-5; author reply 555. 2004
  41. ncbi request reprint Reawakening to the existence of juvenile xanthogranuloma
    Louis P Dehner
    Am J Surg Pathol 29:119-20. 2005
  42. ncbi request reprint Mucoepidermoid carcinoma of the skin: a distinct entity from adenosquamous carcinoma: a case study with a review of the literature
    Wolfram F J Riedlinger
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, MO 63110 1093, USA
    Am J Surg Pathol 29:131-5. 2005
    ..Additionally, the immunophenotype of our case is similar to at least two other cases of cutaneous MEC, as well as MEC of the salivary gland, to support the hypothesis that this neoplasm is adnexal rather than epidermal in origin...
  43. ncbi request reprint Concurrent infantile hemangioendothelioma and mesenchymal hamartoma in a developmentally arrested liver of an infant requiring hepatic transplantation
    Pablo A Bejarano
    Department of Pathology, University of Miami School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz Center Room 2042, Miami, FL 33136, USA
    Pediatr Dev Pathol 6:552-7. 2003
    ..This simultaneous involvement of the liver by a mesenchymal hamartoma and infantile hemangioendothelioma is unique. A review of the literature revealed only one incompletely characterized case with similar findings...
  44. ncbi request reprint Congenital malignant rhabdoid tumor
    Louis P Dehner
    Diagn Cytopathol 32:135-6. 2005
  45. ncbi request reprint Paraganglioma of the vagina: report of a case, including immunohistochemical and ultrastructural findings
    Anjum Hassan
    Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Gynecol Pathol 22:404-6. 2003
    ..The clinical course after the biopsy implied that this neoplasm had been awakened from its functionless dormancy...
  46. ncbi request reprint Dermatofibrosarcoma protuberans of the vulva and groin: detection of COL1A1-PDGFB fusion transcripts by RT-PCR
    Neriman Gokden
    Lauren V Ackerman Laboratory of Surgical Pathology, Barnes Jewish Hospital, Washington University Medical Center, St Louis, MO, USA
    J Cutan Pathol 30:190-5. 2003
    ..The trunk and extremities are the anatomic sites of predilection for DFSP, whereas the vulva and groin are quite uncommon sites of involvement...
  47. ncbi request reprint Successful treatment of inflammatory myofibroblastic tumor with malignant transformation by surgical resection and chemotherapy
    Megan K Dishop
    Department of Pathology, University of Kentuckey Children s Hospital Chandler Medical Center, Lexington, USA
    J Pediatr Hematol Oncol 25:153-8. 2003
    ..He is disease-free after 2 years, representing successful combined surgery and chemotherapy in the treatment of malignant IMT. The use of chemotherapy for aggressive myofibroblastic tumors is reviewed...
  48. ncbi request reprint Perianal rhabdomyosarcoma presenting as a perirectal abscess: A report of 11 cases
    D Ashley Hill
    Department of Pathology, St Jude Children s Research Hospital and University of Tennessee, Memphis TN, USA
    J Pediatr Surg 37:576-81. 2002
    ....