E Warwick Daw
Affiliation: Washington University School of Medicine
- Identifying rare variants from exome scans: the GAW17 experienceSaurabh Ghosh
Human Genetics Unit, Indian Statistical Institute, Kolkata 700018, India
BMC Proc 5:S1. 2011....
- Identifying modifier loci in existing genome scan dataE W Daw
Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO 63108, USA
Ann Hum Genet 72:670-5. 2008..We found that both methods produced scores that are significant on a genome-wide level in some replicates. We conclude that mapping of modifier loci in existing samples is possible with these methods...
- A framework for analyzing both linkage and association: an analysis of Genetic Analysis Workshop 16 simulated dataE Warwick Daw
Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Campus Box 8506, St, Louis, Missouri 63108 USA
BMC Proc 3:S98. 2009..1%) contributions to trait variance may require additional sources of information. All methods examined fared poorly for the smallest in the simulated "polygene" range (h2 of 0.0015 to 0.0002)...
- The Genetic Analysis Workshop 16 Problem 3: simulation of heritable longitudinal cardiovascular phenotypes based on actual genome-wide single-nucleotide polymorphisms in the Framingham Heart StudyAldi T Kraja
Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Campus Box 8506, St, Louis, Missouri 63108, USA
BMC Proc 3:S4. 2009..Smoking was simulated to be commensurate with rates reported by the Centers for Disease Control. Two hundred replications were simulated...