Peter A Crawford

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation
    Peter A Crawford
    Center for Genome Sciences and Department of Medicine, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 106:11276-81. 2009
  2. ncbi Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease
    Rebecca C Schugar
    Department of Medicine, Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, USA
    Curr Opin Clin Nutr Metab Care 15:374-80. 2012
  3. ncbi Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment
    Anna E Wentz
    Department of Medicine, Washington University, St Louis, Missouri 63108, USA
    J Biol Chem 285:24447-56. 2010
  4. ncbi Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet
    Joel R Garbow
    Department of 1Medicine, Washington University, St Louis, Missouri 63110, USA
    Am J Physiol Gastrointest Liver Physiol 300:G956-67. 2011
  5. ncbi Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor
    Fredrik Backhed
    Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 104:606-11. 2007
  6. ncbi Altered systemic ketone body metabolism in advanced heart failure
    Ajit Janardhan
    Division of Cardiovascular Medicine, Department of Medicine, Washington University, St Louis, Missouri 63110, USA
    Tex Heart Inst J 38:533-8. 2011
  7. ncbi Microbial regulation of intestinal radiosensitivity
    Peter A Crawford
    Center for Genome Sciences and Department of Molecular Biology, Washington University School of Medicine, St. Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 102:13254-9. 2005
  8. ncbi Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity
    Sharon Etzion
    Center for Cardiovascular Research, John Milliken Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Mol Cell Cardiol 49:931-40. 2010
  9. ncbi Obligate role for ketone body oxidation in neonatal metabolic homeostasis
    David G Cotter
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 286:6902-10. 2011

Collaborators

Detail Information

Publications9

  1. ncbi Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation
    Peter A Crawford
    Center for Genome Sciences and Department of Medicine, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 106:11276-81. 2009
    ..Together, these results illustrate benefits provided by the gut microbiota during periods of nutrient deprivation, and emphasize the importance of further exploring the relationship between gut microbes and cardiovascular health...
  2. ncbi Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease
    Rebecca C Schugar
    Department of Medicine, Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, USA
    Curr Opin Clin Nutr Metab Care 15:374-80. 2012
    ..This review focuses on the most recent findings that reveal the relationship between low-carbohydrate diets and NAFLD in rodent models and humans...
  3. ncbi Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment
    Anna E Wentz
    Department of Medicine, Washington University, St Louis, Missouri 63108, USA
    J Biol Chem 285:24447-56. 2010
    ..These results indicate that ketotic nutrient environments engage mechanisms that curtail ketolytic capacity, controlling the utilization of ketone bodies in ketotic states...
  4. ncbi Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet
    Joel R Garbow
    Department of 1Medicine, Washington University, St Louis, Missouri 63110, USA
    Am J Physiol Gastrointest Liver Physiol 300:G956-67. 2011
    ..The distinctive nutrient milieu created by long-term administration of this low-carbohydrate, low-protein ketogenic diet in mice evokes unique signatures of nonalcoholic fatty liver disease and whole-body glucose homeostasis...
  5. ncbi Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor
    Fredrik Backhed
    Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 104:606-11. 2007
    ..This organ-specific lymphovascular abnormality can be rescued by allowing embryonic Fiaf-/- intestinal isografts to develop in Fiaf+/+ recipients...
  6. ncbi Altered systemic ketone body metabolism in advanced heart failure
    Ajit Janardhan
    Division of Cardiovascular Medicine, Department of Medicine, Washington University, St Louis, Missouri 63110, USA
    Tex Heart Inst J 38:533-8. 2011
    ..Future studies are needed to determine whether ketone body metabolism serves as a dynamic quantitative biomarker of skeletal myopathy and fatigue in heart failure...
  7. ncbi Microbial regulation of intestinal radiosensitivity
    Peter A Crawford
    Center for Genome Sciences and Department of Molecular Biology, Washington University School of Medicine, St. Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 102:13254-9. 2005
    ..Together, these findings provide insights about the cellular and molecular targets involved in microbial regulation of intestinal radiosensitivity...
  8. ncbi Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity
    Sharon Etzion
    Center for Cardiovascular Research, John Milliken Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Mol Cell Cardiol 49:931-40. 2010
    ..This maladaptive response is associated with hypersensitivity of akt2(-/-) myocardium to β-adrenergic stimulation...
  9. ncbi Obligate role for ketone body oxidation in neonatal metabolic homeostasis
    David G Cotter
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 286:6902-10. 2011
    ..These results indicate the critical metabolic roles of ketone bodies in neonatal metabolism and suggest that distinct tissues exhibit specific metabolic responses to loss of ketone body oxidation...