Joseph Corbo

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint The role of cis-regulatory elements in the design of gene therapy vectors for inherited blindness
    Joseph C Corbo
    Washington University School of Medicine, Department of Pathology and Immunology, Campus Box 8118, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Expert Opin Biol Ther 8:599-608. 2008
  2. pmc CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors
    Joseph C Corbo
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110 1024, USA
    Genome Res 20:1512-25. 2010
  3. pmc The cis-regulatory logic of the mammalian photoreceptor transcriptional network
    Timothy H C Hsiau
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 2:e643. 2007
  4. doi request reprint Inherited diseases of photoreceptors and prospects for gene therapy
    Cynthia L Montana
    Department of Pathology and Immunology, Washington University School of Medicine, Campus Box 8118 660 South Euclid Ave St Louis, MO 63110, USA
    Pharmacogenomics 9:335-47. 2008

Collaborators

  • Cynthia L Montana
  • Timothy H C Hsiau
  • Connie A Myers
  • Jongwoo Lee
  • Claudiu Diaconu
  • Constance L Cepko

Detail Information

Publications4

  1. ncbi request reprint The role of cis-regulatory elements in the design of gene therapy vectors for inherited blindness
    Joseph C Corbo
    Washington University School of Medicine, Department of Pathology and Immunology, Campus Box 8118, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Expert Opin Biol Ther 8:599-608. 2008
    ..In order to target expression of a rescue transgene specifically to the cells in need of therapy, it is necessary to employ a cis-regulatory element (CRE) to drive expression of the transgene specifically in those cells...
  2. pmc CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors
    Joseph C Corbo
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110 1024, USA
    Genome Res 20:1512-25. 2010
    ..In addition, this study pinpoints thousands of noncoding regions of relevance to both Mendelian and complex retinal disease...
  3. pmc The cis-regulatory logic of the mammalian photoreceptor transcriptional network
    Timothy H C Hsiau
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 2:e643. 2007
    ..This study represents the first systematic identification and in vivo validation of CREs in a mammalian neuronal cell type and lays the groundwork for a systems biology of photoreceptor transcriptional regulation...
  4. doi request reprint Inherited diseases of photoreceptors and prospects for gene therapy
    Cynthia L Montana
    Department of Pathology and Immunology, Washington University School of Medicine, Campus Box 8118 660 South Euclid Ave St Louis, MO 63110, USA
    Pharmacogenomics 9:335-47. 2008
    ....

Research Grants4

  1. QUANTITATIVE ANALYSIS AND ENGINEERING OF THE PHOTORECEPTOR TRANSCRIPTION NETWORK
    Joseph C Corbo; Fiscal Year: 2010
    ..It is the aim of our research to significantly expand the repertoire of both natural promoters and synthetic gene circuits available for treating patients with blindness. ..
  2. Gene Regulatory Networks in Rod Photoreceptor Cells
    Joseph Corbo; Fiscal Year: 2007
    ..Dr. Joseph Corbo, the Principal Investigator, is an M.D., Ph.D...
  3. QUANTITATIVE ANALYSIS AND ENGINEERING OF THE PHOTORECEPTOR TRANSCRIPTION NETWORK
    Joseph Corbo; Fiscal Year: 2009
    ..It is the aim of our research to significantly expand the repertoire of both natural promoters and synthetic gene circuits available for treating patients with blindness. ..