Joseph Corbo

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Avian cone photoreceptors tile the retina as five independent, self-organizing mosaics
    Yoseph A Kram
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 5:e8992. 2010
  2. ncbi request reprint The role of cis-regulatory elements in the design of gene therapy vectors for inherited blindness
    Joseph C Corbo
    Washington University School of Medicine, Department of Pathology and Immunology, Campus Box 8118, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Expert Opin Biol Ther 8:599-608. 2008
  3. pmc CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors
    Joseph C Corbo
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110 1024, USA
    Genome Res 20:1512-25. 2010
  4. pmc The cis-regulatory logic of the mammalian photoreceptor transcriptional network
    Timothy H C Hsiau
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 2:e643. 2007
  5. ncbi request reprint Inherited diseases of photoreceptors and prospects for gene therapy
    Cynthia L Montana
    Department of Pathology and Immunology, Washington University School of Medicine, Campus Box 8118 660 South Euclid Ave St Louis, MO 63110, USA
    Pharmacogenomics 9:335-47. 2008

Research Grants

Collaborators

  • Thomas Langmann
  • Yoseph A Kram
  • Cynthia L Montana
  • Timothy H C Hsiau
  • Stephanie Mantey
  • Connie A Myers
  • Claudiu Diaconu
  • Jongwoo Lee
  • Constance L Cepko

Detail Information

Publications5

  1. pmc Avian cone photoreceptors tile the retina as five independent, self-organizing mosaics
    Yoseph A Kram
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 5:e8992. 2010
    ..Our results indicate that the evolutionary pressures that gave rise to the avian retina's various adaptations for enhanced color discrimination also acted to fine-tune its spatial sampling of color and luminance...
  2. ncbi request reprint The role of cis-regulatory elements in the design of gene therapy vectors for inherited blindness
    Joseph C Corbo
    Washington University School of Medicine, Department of Pathology and Immunology, Campus Box 8118, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Expert Opin Biol Ther 8:599-608. 2008
    ..In order to target expression of a rescue transgene specifically to the cells in need of therapy, it is necessary to employ a cis-regulatory element (CRE) to drive expression of the transgene specifically in those cells...
  3. pmc CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors
    Joseph C Corbo
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110 1024, USA
    Genome Res 20:1512-25. 2010
    ..In addition, this study pinpoints thousands of noncoding regions of relevance to both Mendelian and complex retinal disease...
  4. pmc The cis-regulatory logic of the mammalian photoreceptor transcriptional network
    Timothy H C Hsiau
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 2:e643. 2007
    ..This study represents the first systematic identification and in vivo validation of CREs in a mammalian neuronal cell type and lays the groundwork for a systems biology of photoreceptor transcriptional regulation...
  5. ncbi request reprint Inherited diseases of photoreceptors and prospects for gene therapy
    Cynthia L Montana
    Department of Pathology and Immunology, Washington University School of Medicine, Campus Box 8118 660 South Euclid Ave St Louis, MO 63110, USA
    Pharmacogenomics 9:335-47. 2008
    ....

Research Grants1

  1. Gene Regulatory Networks in Rod Photoreceptor Cells
    Joseph Corbo; Fiscal Year: 2007
    ..Dr. Joseph Corbo, the Principal Investigator, is an M.D., Ph.D...