FRANCIS SESSIONS COLE

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype
    Eline van Meel
    Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St, Louis, MO 63110, USA
    BMC Med Genet 14:106. 2013
  2. doi request reprint NIH Consensus Development Conference statement: inhaled nitric-oxide therapy for premature infants
    F Sessions Cole
    Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pediatrics 127:363-9. 2011
  3. ncbi request reprint Population-based estimates of surfactant protein B deficiency
    F S Cole
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63110, USA
    Pediatrics 105:538-41. 2000
  4. ncbi request reprint Defects in surfactant synthesis: clinical implications
    F Sessions Cole
    Division of Newborn Medicine in the Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
    Pediatr Clin North Am 53:911-27, ix. 2006
  5. ncbi request reprint Genetic disorders of neonatal respiratory function
    F S Cole
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, and St Louis Children s Hospital, St Louis, Missouri 63110, U S A
    Pediatr Res 50:157-62. 2001
  6. pmc Population and disease-based prevalence of the common mutations associated with surfactant deficiency
    Tami H Garmany
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pediatr Res 63:645-9. 2008
  7. pmc Comprehensive genetic variant discovery in the surfactant protein B gene
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri 63110, USA
    Pediatr Res 62:170-5. 2007
  8. pmc Inherited surfactant deficiency caused by uniparental disomy of rare mutations in the surfactant protein-B and ATP binding cassette, subfamily a, member 3 genes
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63110, USA
    J Pediatr 155:854-859.e1. 2009
  9. pmc Developmental and genetic regulation of human surfactant protein B in vivo
    Aaron Hamvas
    Division of Newborn Medicine, the Edward Mallinckrodt Department of Pediatrics and St Louis Children s Hospital, St Louis, MO 63110, USA
    Neonatology 95:117-24. 2009
  10. ncbi request reprint Genetic disorders of surfactant proteins
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University and St Louis Children s Hospital, St Louis, MO 63110, USA
    Neonatology 91:311-7. 2007

Research Grants

  1. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    FRANCIS COLE; Fiscal Year: 2009
  2. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    FRANCIS SESSIONS COLE; Fiscal Year: 2010
  3. Genetic Regulation of Surfactant Deficiency
    FRANCIS SESSIONS COLE; Fiscal Year: 2010
  4. Genetic Regulation of Surfactant Deficiency
    FRANCIS COLE; Fiscal Year: 2009
  5. Genetic Basis of Inflammatory Airway Disease
    F Cole; Fiscal Year: 2007
  6. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    F Cole; Fiscal Year: 2007
  7. Mechanisms of Disease in the Newborn Human Infant
    F Cole; Fiscal Year: 2006
  8. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    FRANCIS COLE; Fiscal Year: 2005

Collaborators

Detail Information

Publications17

  1. pmc Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype
    Eline van Meel
    Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St, Louis, MO 63110, USA
    BMC Med Genet 14:106. 2013
    ..Methionyl-tRNA synthetase (MARS) catalyzes the ligation of methionine to its cognate transfer RNA and therefore plays an essential role in protein biosynthesis...
  2. doi request reprint NIH Consensus Development Conference statement: inhaled nitric-oxide therapy for premature infants
    F Sessions Cole
    Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pediatrics 127:363-9. 2011
    ....
  3. ncbi request reprint Population-based estimates of surfactant protein B deficiency
    F S Cole
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63110, USA
    Pediatrics 105:538-41. 2000
    ..Using independent clinical ascertainment and molecular methods in different populations, we sought to determine allele frequency...
  4. ncbi request reprint Defects in surfactant synthesis: clinical implications
    F Sessions Cole
    Division of Newborn Medicine in the Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
    Pediatr Clin North Am 53:911-27, ix. 2006
    ..In contrast to developmental causes of respiratory distress, which may improve as infants and children mature, genetic causes result in both acute and chronic (and potentially irreversible) respiratory failure...
  5. ncbi request reprint Genetic disorders of neonatal respiratory function
    F S Cole
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, and St Louis Children s Hospital, St Louis, Missouri 63110, U S A
    Pediatr Res 50:157-62. 2001
    ..We review examples of genetic variations known to be associated with or cause respiratory distress in infancy...
  6. pmc Population and disease-based prevalence of the common mutations associated with surfactant deficiency
    Tami H Garmany
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pediatr Res 63:645-9. 2008
    ..E292V was over-represented in newborns with RDS suggesting that E292V or its unique haplotype impart increased genetic risk for RDS...
  7. pmc Comprehensive genetic variant discovery in the surfactant protein B gene
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri 63110, USA
    Pediatr Res 62:170-5. 2007
    ....
  8. pmc Inherited surfactant deficiency caused by uniparental disomy of rare mutations in the surfactant protein-B and ATP binding cassette, subfamily a, member 3 genes
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63110, USA
    J Pediatr 155:854-859.e1. 2009
    ..To characterize inheritance of homozygous, rare, recessive loss-of-function mutations in surfactant protein-B (SFTPB) or ATP binding cassette, subfamily A, member 3 (ABCA3) genes in newborns with lethal respiratory failure...
  9. pmc Developmental and genetic regulation of human surfactant protein B in vivo
    Aaron Hamvas
    Division of Newborn Medicine, the Edward Mallinckrodt Department of Pediatrics and St Louis Children s Hospital, St Louis, MO 63110, USA
    Neonatology 95:117-24. 2009
    ..Genetic and developmental disruption of surfactant protein B (SP-B) expression causes neonatal respiratory distress syndrome (RDS)...
  10. ncbi request reprint Genetic disorders of surfactant proteins
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University and St Louis Children s Hospital, St Louis, MO 63110, USA
    Neonatology 91:311-7. 2007
    ..The molecular basis and the genetic and tissue-based approaches to the evaluation of children suspected of having one of these disorders are discussed...
  11. ncbi request reprint Informed consent for genetic research
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63110, USA
    Arch Pediatr Adolesc Med 158:551-5. 2004
    ....
  12. ncbi request reprint Genetic variant characterization in intron 4 of the surfactant protein B gene
    Aaron Hamvas
    Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri, USA
    Hum Mutat 26:494-5. 2005
    ..7, 95% CI 1.0-7.2). Reliable characterization of genetic variants in intron 4 requires both a high fidelity polymerase and sequencing of variant alleles...
  13. pmc Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene
    Amy D McBee
    Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Pediatr Pulmonol 43:443-50. 2008
    ..To determine haplotype background of common mutations in the genes encoding surfactant proteins B and C (SFTPB and SFTPC) and to assess recombination in SFTPC...
  14. ncbi request reprint A major deletion in the surfactant protein-B gene causing lethal respiratory distress
    Daniel J Wegner
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, MO 63110, USA
    Acta Paediatr 96:516-20. 2007
    ..No large deletions in SFTPB have been previously identified...
  15. ncbi request reprint Racial disparity in the frequency of recurrence of preterm birth
    Zachary A F Kistka
    Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63110, USA
    Am J Obstet Gynecol 196:131.e1-6. 2007
    ..We examined the hypothesis that black race independent of other factors increases the risk for extreme preterm birth and its frequency of recurrence at a similar gestational age...
  16. ncbi request reprint Long-term outcomes after infant lung transplantation for surfactant protein B deficiency related to other causes of respiratory failure
    Lisanne M Palomar
    Edward Mallinckrodt Department of Pediatrics, Washington University, St Louis, Missouri 63110, USA
    J Pediatr 149:548-53. 2006
    ..To determine if the outcomes of lung transplantation for infants with surfactant protein-B (SP-B) deficiency are unique...
  17. pmc Quantification of rare allelic variants from pooled genomic DNA
    Todd E Druley
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Nat Methods 6:263-5. 2009
    ..Our base-calling algorithm, SNPSeeker, derived from large deviation theory, detected single-nucleotide polymorphisms present at frequencies below the raw error rate of the sequencing platform...

Research Grants18

  1. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    FRANCIS COLE; Fiscal Year: 2009
    ..These studies will suggest new strategies for diagnosis, treatment, and prevention of neonatal respiratory distress. ..
  2. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    FRANCIS SESSIONS COLE; Fiscal Year: 2010
    ....
  3. Genetic Regulation of Surfactant Deficiency
    FRANCIS SESSIONS COLE; Fiscal Year: 2010
    ..These studies will lead to improved diagnostic capabilities and suggest novel strategies to correct surfactant deficiency in newborn infants. ..
  4. Genetic Regulation of Surfactant Deficiency
    FRANCIS COLE; Fiscal Year: 2009
    ..These studies will lead to improved diagnostic capabilities and suggest novel strategies to correct surfactant deficiency in newborn infants. ..
  5. Genetic Basis of Inflammatory Airway Disease
    F Cole; Fiscal Year: 2007
    ..This career development program will train young scientists to use state of the art methods in genetics and genomics to develop new diagnostic and therapeutic strategies for asthma, cystic fibrosis, and COPD. (End of Abstract) ..
  6. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    F Cole; Fiscal Year: 2007
    ..These studies will suggest new strategies for diagnosis, treatment, and prevention of neonatal respiratory distress. ..
  7. Mechanisms of Disease in the Newborn Human Infant
    F Cole; Fiscal Year: 2006
    ..As such, this program should provide for new pediatric scholars to lead the way for future advances in this important area of child health. ..
  8. EPIDEMIOLOGY OF SURFACTANT PROTEIN-B DEFICIENCY
    FRANCIS COLE; Fiscal Year: 2005
    ....