John C Clohisy

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Acetabular and femoral radiographic abnormalities associated with labral tears
    Michael W Peelle
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 441:327-33. 2005
  2. ncbi Revision total hip arthroplasty: the patient's perspective
    Robert L Barrack
    Department of Orthopaedic Surgery, One Barnes Jewish Hospital Plaza, Suite 11300, St Louis, MO 63110, USA
    Clin Orthop Relat Res 453:173-7. 2006
  3. pmc Osseous remodeling after femoral head-neck junction osteochondroplasty
    Nader A Nassif
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300 West Pavilion, St Louis, MO 63110, USA
    Clin Orthop Relat Res 468:511-8. 2010
  4. ncbi Tumor necrosis factor-alpha mediates polymethylmethacrylate particle-induced NF-kappaB activation in osteoclast precursor cells
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Orthop Res 20:174-81. 2002
  5. ncbi Periacetabular osteotomy in the treatment of severe acetabular dysplasia. Surgical technique
    John C Clohisy
    St Louis Shriners Hospital for Children, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 88:65-83. 2006
  6. ncbi Preliminary assessment and treatment guidelines for hip disorders in young adults
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 441:168-79. 2005
  7. pmc Treatment of anterior femoroacetabular impingement with combined hip arthroscopy and limited anterior decompression
    John C Clohisy
    Department of Orthopedic Surgery, Barnes Jewish Hospital Washington University School of Medicine, St Louis, Missouri, USA
    Iowa Orthop J 25:164-71. 2005
  8. ncbi Periacetabular osteotomy for the treatment of severe acetabular dysplasia
    John C Clohisy
    St Louis Shriners Hospital for Children and Barnes Jewish Hospital at Washington University School of Medicine, 660 South Euclid, Campus Box 8233, St Louis, MO 63110, USA
    J Bone Joint Surg Am 87:254-9. 2005
  9. pmc Medial translation of the hip joint center associated with the Bernese periacetabular osteotomy
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine and St Louis Shriner s Hospital for Children, One Barnes Jewish Hospital Plaza, St Louis, Missouri 63110, USA
    Iowa Orthop J 24:43-8. 2004
  10. pmc Surgical procedure profile in a comprehensive hip surgery program
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University Medical School, St Louis, MO 63110, USA
    Iowa Orthop J 26:63-8. 2006

Detail Information

Publications93

  1. ncbi Acetabular and femoral radiographic abnormalities associated with labral tears
    Michael W Peelle
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 441:327-33. 2005
    ..See the Guidelines for Authors for a complete description of levels of evidence...
  2. ncbi Revision total hip arthroplasty: the patient's perspective
    Robert L Barrack
    Department of Orthopaedic Surgery, One Barnes Jewish Hospital Plaza, Suite 11300, St Louis, MO 63110, USA
    Clin Orthop Relat Res 453:173-7. 2006
    ....
  3. pmc Osseous remodeling after femoral head-neck junction osteochondroplasty
    Nader A Nassif
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300 West Pavilion, St Louis, MO 63110, USA
    Clin Orthop Relat Res 468:511-8. 2010
    ..There were no femoral neck fractures. The deformity correction achieved with femoral head-neck osteochondroplasty is maintained and recorticalization occurs in the majority of cases during the first two years...
  4. ncbi Tumor necrosis factor-alpha mediates polymethylmethacrylate particle-induced NF-kappaB activation in osteoclast precursor cells
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Orthop Res 20:174-81. 2002
    ..Thus, PMMA particle activation of NF-kappaB is a secondary event resulting from enhanced TNF expression and is independent of LPS contamination...
  5. ncbi Periacetabular osteotomy in the treatment of severe acetabular dysplasia. Surgical technique
    John C Clohisy
    St Louis Shriners Hospital for Children, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 88:65-83. 2006
    ....
  6. ncbi Preliminary assessment and treatment guidelines for hip disorders in young adults
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 441:168-79. 2005
    ..We outline general guidelines for the assessment and treatment of hip pain in young adult patients...
  7. pmc Treatment of anterior femoroacetabular impingement with combined hip arthroscopy and limited anterior decompression
    John C Clohisy
    Department of Orthopedic Surgery, Barnes Jewish Hospital Washington University School of Medicine, St Louis, Missouri, USA
    Iowa Orthop J 25:164-71. 2005
    ....
  8. ncbi Periacetabular osteotomy for the treatment of severe acetabular dysplasia
    John C Clohisy
    St Louis Shriners Hospital for Children and Barnes Jewish Hospital at Washington University School of Medicine, 660 South Euclid, Campus Box 8233, St Louis, MO 63110, USA
    J Bone Joint Surg Am 87:254-9. 2005
    ....
  9. pmc Medial translation of the hip joint center associated with the Bernese periacetabular osteotomy
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine and St Louis Shriner s Hospital for Children, One Barnes Jewish Hospital Plaza, St Louis, Missouri 63110, USA
    Iowa Orthop J 24:43-8. 2004
    ..This study demonstrates that in addition to optimizing femoral head coverage, a major and distinct advantage of the periacetabular osteotomy is reproducible and consistent medial translation of the hip joint center...
  10. pmc Surgical procedure profile in a comprehensive hip surgery program
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University Medical School, St Louis, MO 63110, USA
    Iowa Orthop J 26:63-8. 2006
    ..These data underscore the variety of surgical techniques needed to treat this patient population, and emphasize an expanding role for nonarthroplasty surgical interventions...
  11. ncbi NF-kB signaling blockade abolishes implant particle-induced osteoclastogenesis
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300, West Pavillion, St Louis, MO 63110, USA
    J Orthop Res 22:13-20. 2004
    ..Again, this inhibitor efficiently blocked particle-induced osteoclastogenesis. Thus, we have shown that pharmaceutical and molecular blockade of NF-kB activation inhibits PMMA particle-directed osteoclastogenesis in vitro...
  12. ncbi Patient compliance with clinical follow-up after total joint arthroplasty
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, One Barnes Hospital Plaza, Suite 11300 West Pavilion, St Louis, MO 63110, USA
    J Bone Joint Surg Am 90:1848-54. 2008
    ..The purpose of this study was to evaluate patient compliance with early clinical follow-up after total hip arthroplasty or total knee arthroplasty...
  13. ncbi RANKL is an essential cytokine mediator of polymethylmethacrylate particle-induced osteoclastogenesis
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, School of Medicine, One Barnes Jewish Hospital Plaza, 11300 West Pavilion, Campus Box 8233, St Louis, Missouri 63110, USA
    J Orthop Res 21:202-12. 2003
    ....
  14. ncbi The frog-leg lateral radiograph accurately visualized hip cam impingement abnormalities
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 462:115-21. 2007
    ..6 mm for hips with impingement versus 9.3 mm for control hips). The frog-leg lateral radiograph provides accurate visualization of the femoral head-neck offset in patients being evaluated for femoroacetabular impingement...
  15. pmc Reliability of various observers in determining common radiographic parameters of adult hip structural anatomy
    John C Carlisle
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    Iowa Orthop J 31:52-8. 2011
    ..The purpose of this study was to determine the interobserver and intraobserver reliability of various musculoskeletal physicians in performing selected measurements of adult structural hip anatomy...
  16. pmc What is the prognosis of revision total hip arthroplasty in patients 55 years and younger?
    Muyibat A Adelani
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St Louis, MO, 63110, USA
    Clin Orthop Relat Res 472:1518-25. 2014
    ..Revision THAs are expected to increase; however, few studies have characterized the prognosis of revision THAs in younger patients...
  17. pmc Do young, active patients perceive advantages after surface replacement compared to cementless total hip arthroplasty?
    Robert L Barrack
    Department of Orthopaedic Surgery, Washington University School of Medicine Barnes Jewish Hospital, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, 11300 West Pavilion, Campus Box 8233, St Louis, MO, 63110, USA
    Clin Orthop Relat Res 471:3803-13. 2013
    ..Potential advantages suggested but not confirmed for surface replacement arthroplasty (SRA) over THA include lower frequency of limp, less thigh pain, less limb length discrepancy, and higher activity...
  18. pmc Large acetabular defects can be managed with cementless revision components
    E Scott Paxton
    Department of Orthopaedics, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 469:483-93. 2011
    ..While cementless hemispherical components have been utilized to treat large acetabular defects, most reports have not focused specifically on patients with extensive deficiencies...
  19. pmc Surgical treatment of femoroacetabular impingement: a systematic review of the literature
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300 West Pavilion, St Louis, MO 63110, USA
    Clin Orthop Relat Res 468:555-64. 2010
    ..Long-term followup is needed to determine survivorship and impact on osteoarthritis progression and natural history...
  20. pmc The incidence of acetabular osteolysis in young patients with conventional versus highly crosslinked polyethylene
    Nathan A Mall
    Department of Orthopedics, Washington University School of Medicine, Barnes Jewish Hospital, One Barnes Jewish Hospital Plaza, 11300 West Pavilion, St Louis, MO 63110, USA
    Clin Orthop Relat Res 469:372-81. 2011
    ..Previous literature has focused on the amount of polyethylene wear comparing highly crosslinked polyethylene (HXPLE) with conventional liners but has not clarified the relative incidence of osteolysis with these two liners...
  21. pmc Are younger patients undergoing TKAs appropriately characterized as active?
    James A Keeney
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid, CB 8233, St Louis, MO, 63110, USA
    Clin Orthop Relat Res 472:1210-6. 2014
    ..Patient age (≤ 55 years) and preoperative diagnosis have been used to define this patient group, with the presumption that these patients are more active than older patients with similar indications for TKA...
  22. pmc Persistent structural disease is the most common cause of repeat hip preservation surgery
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes Jewish Hospital, 660 S Euclid Avenue, Box 8233, St Louis, MO, 63110, USA
    Clin Orthop Relat Res 471:3788-94. 2013
    ..Hip preservation surgery has become more commonplace, yet when it fails, it is unclear why it does so. Understanding failed procedures should lead to improved surgical results...
  23. pmc Radiographic evaluation of the hip has limited reliability
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Hospital Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 467:666-75. 2009
    ..Accordingly, a more clear set of definitions and measurements must be developed to allow for more reliable diagnosis of early hip disease...
  24. pmc Clinical presentation of patients with symptomatic anterior hip impingement
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 467:638-44. 2009
    ..The patients were relatively active, yet demonstrated restrictions of function and overall health. These data may facilitate diagnosis of this disorder...
  25. ncbi Optimal initial dose adjustment of warfarin in orthopedic patients
    Petra A Lenzini
    Washington University in St Louis, St Louis, MO 63110, USA
    Ann Pharmacother 41:1798-804. 2007
    ..Dosing algorithms have not been widely adopted because they require a fixed initial warfarin dose (eg, 5 mg) and are not tailored to other factors that may affect the international normalized ratio (INR)...
  26. pmc Why do hip arthroscopy procedures fail?
    Ljiljana Bogunovic
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Hospital Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 471:2523-9. 2013
    ..Knowledge regarding the reasons for treatment failures may also improve surgical decision making...
  27. doi Descriptive epidemiology of femoroacetabular impingement: a North American cohort of patients undergoing surgery
    John C Clohisy
    John C Clohisy, Washington University, 11300 West Pavilion, Campus Box 8233, One Barnes Jewish Hospital Plaza, St Louis, MO 63110
    Am J Sports Med 41:1348-56. 2013
    ..The authors have therefore established a multicenter, prospective, longitudinal cohort of patients undergoing surgery for symptomatic FAI...
  28. pmc Revision total knee arthroplasty for major osteolysis
    R Stephen J Burnett
    Department of Orthopaedic Surgery, Washington University School of Medicine and Barnes Jewish Hospital, St Louis, Missouri, USA
    Iowa Orthop J 29:28-37. 2009
    ..Significant improvement in clinical and radiographic outcomes may be anticipated using these surgical techniques...
  29. pmc Has total hip arthroplasty in patients 30 years or younger improved? A systematic review
    Muyibat A Adelani
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 471:2595-601. 2013
    ..However, THA in very young patients historically has been associated with lower survivorship, and it is unclear whether this, or results pertaining to pain and function, has improved with contemporary THA...
  30. pmc What are the factors associated with acetabular correction in Perthes-like hip deformities?
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Hospital Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 470:3439-45. 2012
    ..Nevertheless, the necessity and indications for surgical correction of associated acetabular dysplasia have not been established...
  31. ncbi The reliability of arthroscopic classification of acetabular rim labrochondral disease
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Sports Med 40:2224-9. 2012
    ..Yet, the reliability of arthroscopic hip disease classification has not been well defined. Purpose/..
  32. pmc Stride activity level in young and middle-aged adults with hip disorders
    Marcie Harris-Hayes
    Program in Physical Therapy, Washington University Medical School, Campus Box 8502, St Louis, MO 63108, USA
    Physiother Theory Pract 28:333-43. 2012
    ..To determine the activity level, represented by total daily strides (TDS), of young and middle-aged adults with hip disorders and asymptomatic controls and to assess the association between TDS and self-report functional measures...
  33. pmc Does previous reconstructive surgery influence functional improvement and deformity correction after periacetabular osteotomy?
    Gregory G Polkowski
    Department of Orthopaedic Surgery, New England Musculoskeletal Institute, University of Connecticut Health Center, Farmington, CT, USA
    Clin Orthop Relat Res 470:516-24. 2012
    ..However, the degree to which function and radiographic deformity are corrected in patients with more severe deformities that have undergone previous reconstructive pelvic or femoral osteotomies is unclear...
  34. ncbi Combined hip arthroscopy and limited open osteochondroplasty for anterior femoroacetabular impingement
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
    J Bone Joint Surg Am 92:1697-706. 2010
    ....
  35. ncbi The value of intraoperative Gram stain in revision total knee arthroplasty
    Patrick M Morgan
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 91:2124-9. 2009
    ..While intraoperative Gram stains are routinely performed during revision total knee arthroplasty, their value remains unclear...
  36. pmc 2011 Marshall Urist Young Investigator Award: when to release patients to high-impact activities after hip resurfacing
    Katherine M Bedigrew
    Washington University School of Medicine, St Louis, MO, USA
    Clin Orthop Relat Res 470:299-306. 2012
    ..Femoral neck fracture is an arthroplasty-related complication unique to surface replacement arthroplasty. However, it is unclear regarding whether patients are at lower risk for fracture after a certain postoperative time...
  37. doi Clinical and radiographic predictors of intra-articular hip disease in arthroscopy
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Sports Med 39:296-303. 2011
    ..Nevertheless, contemporary diagnostic tools have significant limitations in predicting severity of disease preoperatively...
  38. ncbi Labral disease associated with femoroacetabular impingement: do we need to correct the structural deformity?
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    J Arthroplasty 24:114-9. 2009
    ..These preliminary data suggest that patients with cam femoroacetabular impingement may have improved clinical outcomes when the impingement deformity is corrected...
  39. pmc The fate of grafting acetabular defects during revision total hip arthroplasty
    Nathan A Mall
    Department of Orthopaedics, Washington University Barnes Jewish Hospital, St Louis, MO, USA
    Clin Orthop Relat Res 468:3286-94. 2010
    ..Previous studies using plain radiographs report high rates of graft incorporation. However, given plain radiographs underestimate osteolysis, it is unclear whether plain radiographs adequately reflect graft fill or incorporation...
  40. pmc Combined periacetabular and femoral osteotomies for severe hip deformities
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 467:2221-7. 2009
    ..These data indicate combined PAO/PFO is associated with improved hip function in most patients. These clinical results are comparable to those obtained with isolated PAO for lesser hip deformities...
  41. ncbi Periacetabular osteotomy for the treatment of acetabular dysplasia associated with major aspherical femoral head deformities
    John C Clohisy
    St Louis Shriners Hospital for Children, Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 89:1417-23. 2007
    ..The optimal method of surgical correction for these challenging combined deformities remains controversial...
  42. pmc Anterior femoroacetabular impingement: a diverse disease with evolving treatment options
    Lukas P Zebala
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    Iowa Orthop J 27:71-81. 2007
    ..FAI is now more commonly diagnosed and there is an increasing need for a thorough understanding of the broad spectrum of clinical presentation for the disease as well as more precise definition of the possible surgical options...
  43. pmc NFAT2 is an essential mediator of orthopedic particle-induced osteoclastogenesis
    Yasuhiro Yamanaka
    Department of Orthopedics, Washington University School of Medicine, One Barnes Hospital Plaza, 11300 West Pavilion, Campus Box 8233, St Louis, Missouri 63110, USA
    J Orthop Res 26:1577-84. 2008
    ..Thus, our findings demonstrate that activation of the NFAT pathway in conjunction with MAP kinases is essential for basal and PMMA-stimulated osteoclastogenesis...
  44. ncbi Direct inhibition of NF-kappa B blocks bone erosion associated with inflammatory arthritis
    John C Clohisy
    Department of Orthopaedic Research Laboratory, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Immunol 171:5547-53. 2003
    ..Thus, NF-kappaB appears to be the centerpiece of inflammatory-osteolytic arthritis and direct inhibition of this transcription factor by unique and novel I-kappaB mutant proteins blocks manifestation of the disease...
  45. doi Accuracy of acetabular component position in hip arthroplasty
    Robert L Barrack
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St Louis, MO 63110 E mail address for R L Barrack
    J Bone Joint Surg Am 95:1760-8. 2013
    ..The purpose of this study was to examine the frequency in which acetabular components are placed within a predetermined target range...
  46. pmc Do fluoroscopy and postoperative radiographs correlate for periacetabular osteotomy corrections?
    Charles L Lehmann
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 S Euclid, 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 470:3508-14. 2012
    ..Fluoroscopy is used by some surgeons to assess intraoperative acetabular correction but it is unclear whether the features observed by fluoroscopy accurately reflect those on postoperative radiographs...
  47. doi Periacetabular osteotomy and combined femoral head-neck junction osteochondroplasty: a minimum two-year follow-up cohort study
    Nader A Nassif
    Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Bone Joint Surg Am 94:1959-66. 2012
    ....
  48. pmc Clinical outcomes analysis of conservative and surgical treatment of patients with clinical indications of prearthritic, intra-articular hip disorders
    Devyani Hunt
    Section, Physical Medicine and Rehabilitation, Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    PM R 4:479-87. 2012
    ....
  49. ncbi The reliability and variation of acetabular component anteversion measurements from cross-table lateral radiographs
    Ryan M Nunley
    Washington University School of Medicine, Department of Orthopaedic Surgery, Saint Louis, Missouri 63110, USA
    J Arthroplasty 26:84-7. 2011
    ..Although CL imaging provides acceptable assessment of general component position, it has limited use for precise analysis in research, outcome reporting, or determination of cause of implant failure...
  50. pmc Incidence and characteristics of femoral deformities in the dysplastic hip
    John C Clohisy
    Department of Orthopaedic Surgery, Barnes Jewish Hospital, Washington University School of Medicine, One Barnes Hospital Plaza, St Louis, MO 63110, USA
    Clin Orthop Relat Res 467:128-34. 2009
    ..Identifying and treating these abnormalities may optimize joint congruency and minimize secondary impingement after acetabular reorientation...
  51. ncbi Revision total knee arthroplasty: the patient's perspective
    Robert L Barrack
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 464:146-50. 2007
    ....
  52. doi Minimal incision surgery as a risk factor for early failure of total knee arthroplasty
    Robert L Barrack
    Department of Orthopaedic Surgery, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    J Arthroplasty 24:489-98. 2009
    ..001). Minimal incision surgery TKA accounted for a substantial percentage of revision TKA in recent years at these centers. The high prevalence of MIS failures occurring within 24 months is disturbing and warrants further investigation...
  53. doi Coxa profunda is not a useful radiographic parameter for diagnosing pincer-type femoroacetabular impingement
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 95:417-23. 2013
    ..Our hypothesis was that coxa profunda is a very common radiographic finding in females and is not a finding that is specifically associated with pincer-type femoroacetabular impingement...
  54. doi Clinical presentation of symptomatic acetabular dysplasia in skeletally mature patients
    Ryan M Nunley
    Department of Orthopaedic Surgery, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, MO, USA
    J Bone Joint Surg Am 93:17-21. 2011
    ..The purpose of this study was to prospectively determine the early clinical presentation of symptomatic acetabular dysplasia in skeletally mature patients...
  55. doi Arthroscopic treatment of labral tears after a previous pemberton osteotomy
    Sandra E Klein
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Pediatr Orthop 30:549-53. 2010
    ..All the 3 patients were subsequently diagnosed with and successfully treated for symptomatic acetabular labral damage. All patients were informed that data concerning their case would be submitted for publication...
  56. pmc What is the evidence for total knee arthroplasty in young patients?: a systematic review of the literature
    James A Keeney
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 469:574-83. 2011
    ..TKA is commonly performed to treat advanced inflammatory and degenerative knee arthritis. With increasing use in younger patients, it is important to define the best practices to enhance clinical performance and implant longevity...
  57. doi Radiographic structural abnormalities associated with premature, natural hip-joint failure
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
    J Bone Joint Surg Am 93:3-9. 2011
    ....
  58. pmc Iliopsoas bursa injections can be beneficial for pain after total hip arthroplasty
    Ryan M Nunley
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 468:519-26. 2010
    ....
  59. doi Readmission following total knee arthroplasty: venous thromboembolism as a "never event" is a counterproductive misnomer
    Muyibat A Adelani
    Department of Orthopaedic Surgery, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    J Arthroplasty 28:747-50. 2013
    ..3%), and all occurred despite adequate prophylaxis. The cost of bleeding, wound complications, infection, and limited motion each exceeded the cost of VTE. These results challenge the identification of VTE as a "never event."..
  60. ncbi Clinical diagnosis of femoroacetabular impingement
    Jeffrey J Nepple
    Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Am Acad Orthop Surg 21:S16-9. 2013
    ..Clinical and physical examination findings must be viewed collectively because no single pathognomonic finding exists for FAI. Nevertheless, common components of the history and physical examination do suggest a diagnosis of FAI. ..
  61. ncbi Diagnostic imaging of femoroacetabular impingement
    Jeffrey J Nepple
    Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Am Acad Orthop Surg 21:S20-6. 2013
    ..Three-dimensional imaging such as MRI and CT often is obtained for the evaluation of labral and cartilage pathology, definition of bony anatomy, and surgical planning. ..
  62. pmc Do plain radiographs correlate with CT for imaging of cam-type femoroacetabular impingement?
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 S Euclid, 11300 West Pavilion, Campus Box 8233, St Louis, MO, USA
    Clin Orthop Relat Res 470:3313-20. 2012
    ..It is unclear, however, whether the plain radiographs accurately reflect the findings on three-dimensional imaging...
  63. doi Radiographic findings of femoroacetabular impingement in National Football League Combine athletes undergoing radiographs for previous hip or groin pain
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    Arthroscopy 28:1396-403. 2012
    ..The purpose of this study was to investigate the prevalence of radiographic findings of femoroacetabular impingement (FAI) in elite football players with a history of hip pain or groin injury who underwent radiographs...
  64. pmc Treatment of posttraumatic labral interposition with surgical hip dislocation and labral repair
    Jeffrey J Nepple
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    Iowa Orthop J 31:187-92. 2011
    ..At two-year follow-up, the patient had an excellent clinical and radiographic outcome...
  65. doi The Shenton line in the diagnosis of acetabular dysplasia in the skeletally mature patient
    Peter C Rhee
    Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Bone Joint Surg Am 93:35-9. 2011
    ..The purpose of the present study was to determine the reliability and accuracy of the Shenton line in the diagnosis of acetabular dysplasia in the skeletally mature patient...
  66. doi Early intra-articular hip disease presenting with posterior pelvic and groin pain
    Heidi Prather
    Section, Physical Medicine and Rehabilitation, Department of Orthopedic Surgery, Washington University School of Medicine, One Barnes Plaza, Suite 11300, St Louis, MO 64110, USA
    PM R 1:809-15. 2009
    ..To determine whether posterior pelvic pain is associated with intra-articular hip abnormalities (labral tears and early degenerative changes) in patients with minimal-to-no radiographic abnormalities...
  67. ncbi The fate of the unexpected positive intraoperative cultures after revision total knee arthroplasty
    Robert L Barrack
    Department of Orthopaedic Surgery, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    J Arthroplasty 22:94-9. 2007
    ..Two of these patients became reinfected within a year. A single positive intraoperative culture after revision total knee arthroplasty does not mandate further treatment in the absence of any other signs of infection...
  68. ncbi Clinical presentation of patients with tears of the acetabular labrum
    R Stephen J Burnett
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 88:1448-57. 2006
    ..We sought to define the clinical characteristics associated with symptomatic acetabular labral tears by reviewing a group of patients who had an arthroscopically confirmed diagnosis...
  69. pmc Reliability and agreement of hip range of motion and provocative physical examination tests in asymptomatic volunteers
    Heidi Prather
    Section Physical Medicine and Rehabilitation, Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300, Campus Box 8233, St Louis, MO 63110, USA
    PM R 2:888-95. 2010
    ....
  70. ncbi Failure of the American College of Chest Physicians-1A protocol for lovenox in clinical outcomes for thromboembolic prophylaxis
    R Stephen J Burnett
    Department of Orthopaedic Surgery, Washington University School of Medicine, and Barnes Jewish Hospital, St Louis, Missouri, USA
    J Arthroplasty 22:317-24. 2007
    ..Surgical site complications requiring readmission or reoperation should be considered "major" complications...
  71. pmc Unstable SCFE: review of treatment modalities and prevalence of osteonecrosis
    Ira Zaltz
    Department of Orthopaedic Surgery, William Beaumont Hospital, Royal Oak, MI 48073, USA
    Clin Orthop Relat Res 471:2192-8. 2013
    ..As such, the rates of osteonecrosis and complications after current treatments of unstable SCFE must be compared with those of newer surgical techniques...
  72. ncbi Assessing readmission databases: how reliable is the information?
    James A Keeney
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    J Arthroplasty 27:72-6.e1-2. 2012
    ..66, 77, 78, and 998.59) in 70% of cases. The findings of our study raise questions regarding the validity of accepting information obtained from larger databases without closer scrutiny...
  73. pmc Is routine mid-term total hip arthroplasty surveillance beneficial?
    James A Keeney
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 470:3220-6. 2012
    ..Although mid-term followup (4-10 years) has been performed to follow cohorts of patients, the benefit of observing individual patients regardless of symptoms has not been established...
  74. ncbi Do patients return to work after hip arthroplasty surgery
    Ryan M Nunley
    Washington University Barnes Jewish Hospital, Department of Orthopaedics, Saint Louis, Missouri 63110, USA
    J Arthroplasty 26:92-98.e1-3. 2011
    ..4%), with the vast majority returning to their preoperative occupation, and very few (2.3%) were limited in their ability to return to work because of their operative hip...
  75. ncbi Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis
    John C Clohisy
    Department of Orthopaedics and Cell Biology and Physiology, Washington University School of Medicine, One Barnes Hospital Plaza, 11300 West Pavilion Campus, Box 8233, St Louis, Missouri 63110, USA
    J Orthop Res 24:1358-65. 2006
    ..Thus, NBD peptide is considered as a promising modality to regulate inflammatory osteolysis...
  76. doi AOA symposium. Hip disease in the young adult: current concepts of etiology and surgical treatment
    John C Clohisy
    Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 90:2267-81. 2008
  77. pmc Periacetabular osteotomy: a systematic literature review
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
    Clin Orthop Relat Res 467:2041-52. 2009
    ..These data indicate periacetabular osteotomy provides pain relief and improved hip function in most patients over short- to midterm followup. The current evidence is primarily Level IV...
  78. doi Arthroscopic disease classification and interventions as an adjunct in the treatment of acetabular dysplasia
    James R Ross
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Sports Med 39:72S-8S. 2011
    ..Improved understanding of intra-articular disease patterns associated with hip dysplasia will help delineate the role of arthroscopy as an adjunct to osteotomy surgery for dysplastic hips...
  79. ncbi Surgical management of the problematic hip in adolescent and young adult patients
    Perry L Schoenecker
    Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Am Acad Orthop Surg 19:275-86. 2011
    ..Restoration of more normal proximal femoral morphology results in marked improvement in functional outcome. Effective orthopaedic management requires an understanding of the mechanisms of hip disease as well as surgical expertise...
  80. doi Imaging structural abnormalities in the hip joint: instability and impingement as a cause of osteoarthritis
    Young Jo Kim
    Department of Orthopaedic Surgery, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Semin Musculoskelet Radiol 12:334-45. 2008
    ..Additionally, we will illustrate the use of MRI imaging to detect subtle anatomic abnormalities, as well as the use of biochemical imaging techniques such as dGEMRIC to guide clinical decision making...
  81. pmc Function and fixation of total hip arthroplasty in patients 25 years of age or younger
    John C Clohisy
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Orthop Relat Res 468:3207-13. 2010
    ..The functional improvements in this group of patients are not well documented and whether the condition for which the surgery is performed influences function...
  82. pmc Genetic-based dosing in orthopedic patients beginning warfarin therapy
    Eric A Millican
    Department of Medicine, Washington University in St Louis, MO 63110, USA
    Blood 110:1511-5. 2007
    ..If validated, this model should provide a safer, more effective process for initiating warfarin therapy...
  83. ncbi Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor
    Sabiha Abbas
    Department of Orthopaedics, Washington University School of Medicine, St Louis, MO 63110, USA
    Cytokine 22:33-41. 2003
    ..Importantly, these effects are mediated via a mechanism requiring the TNF type-1 receptor...
  84. ncbi Revision total knee arthroplasty for restricted motion
    James A Keeney
    Department of Orthopedic Surgery, Wilford Hall Medical Center USAF, San Antonio, TX, USA
    Clin Orthop Relat Res 440:135-40. 2005
    ..LEVEL OF EVIDENCE: Therapeutic study, Level III-1 (retrospective comparative study). See the Guidelines for Authors for a complete description of levels of evidence...
  85. pmc Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies
    Yousef Abu-Amer
    Department of Orthopaedic Surgery and Department of Cell Biology and Physiology, Washington University School of Medicine, Barnes Hospital Plaza, Saint Louis, Missouri 63110, USA
    Arthritis Res Ther 9:S6. 2007
    ..An appreciation of the complex network that leads to these cellular and inflammatory responses will form a foundation on which to develop therapeutic interventions to combat inflammatory periprosthetic bone loss...
  86. ncbi Efficacy of combined modality prophylaxis including short-duration warfarin to prevent venous thromboembolism after total hip arthroplasty
    James A Keeney
    Department of Orthopaedic Surgery, Washington University School of Medicine, 660 So Euclid, Campus Box 8233, St Louis, MO 63110, USA
    J Arthroplasty 21:469-75. 2006
    ..The combination of short-duration warfarin and mechanical prophylaxis with predischarge ultrasound screening was safe and effective in limiting the occurrence of venous thromboembolism...
  87. ncbi Entrapment of the sciatic nerve by the femoral neck following closed reduction of a hip prosthesis : a case report
    Fraser J Leversedge
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 84:1210-3. 2002
  88. ncbi Hip biomechanics
    Gregory G Polkowski
    Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Sports Med Arthrosc 18:56-62. 2010
    ....
  89. ncbi Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency. A case report
    Priya K Gopalan
    Department of Medicine, Washington University School of Medicine, Mailstop 8056, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Bone Joint Surg Am 89:389-91. 2007
  90. ncbi Treatment of periprosthetic femoral shaft nonunion
    Alpesh A Patel
    Department of Orthopaedic Surgery, Washington University at Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    J Arthroplasty 21:435-42. 2006
    ..Successful treatment of periprosthetic femoral shaft nonunion yielded excellent pain relief, improved function, and patient satisfaction. However, complication and reoperation rates remain high...
  91. ncbi Progressive peroneal nerve palsy in a varus arthritic knee. A case report
    Gary B Fetzer
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at School of Medicine, One Barnes Jewish Hospital Plaza, West Pavilion, Suite 11300, St Louis, MO 63110, USA
    J Bone Joint Surg Am 86:1538-40. 2004
  92. ncbi Association of third body embedment with rim damage in retrieved acetabular liners
    Hannah J Lundberg
    Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA
    Clin Orthop Relat Res 465:133-9. 2007
    ....
  93. ncbi Hip arthroscopy: an emerging gold standard
    Paul E Beaule
    Arthroscopy 23:682. 2007