Matthew A Ciorba

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Indoleamine 2,3 dioxygenase in intestinal disease
    Matthew A Ciorba
    Division of Gastroenterology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Curr Opin Gastroenterol 29:146-52. 2013
  2. pmc A gastroenterologist's guide to probiotics
    Matthew A Ciorba
    Department of Medicine, Division of Gastroenterology, Washington University, St Louis School of Medicine, St Louis, Missouri 63110, USA
    Clin Gastroenterol Hepatol 10:960-8. 2012
  3. pmc Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner
    Matthew A Ciorba
    Division of Gastroenterology, Washington University Saint Louis, 660 South Euclid Avenue, Box 8124, Saint Louis, MO 63110, USA
    Gut 61:829-38. 2012
  4. pmc IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice
    Ameet I Thaker
    Division of Gastroenterology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Gastroenterology 145:416-25.e1-4. 2013
  5. pmc Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity
    Nitin K Gupta
    Division of Gastroenterology, Washington University in Saint Louis School of Medicine, St Louis, Missouri, USA
    Inflamm Bowel Dis 18:1214-20. 2012
  6. pmc Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis
    Matthew A Ciorba
    Division of Gastroenterology, Washington University, St Louis, MO 63110, USA
    J Immunol 184:3907-16. 2010
  7. doi request reprint Microbial influences on the small intestinal response to radiation injury
    Christopher D Packey
    Division of Gastroenterology, Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA
    Curr Opin Gastroenterol 26:88-94. 2010
  8. pmc Biomarkers in inflammatory bowel disease: current practices and recent advances
    Heba N Iskandar
    Division of Gastroenterology, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA
    Transl Res 159:313-25. 2012
  9. doi request reprint Probiotics as therapy in gastroenterology: a study of physician opinions and recommendations
    Michael D Williams
    Saint Louis University School of Medicine, St Louis, MO 63110, USA
    J Clin Gastroenterol 44:631-6. 2010
  10. pmc Patients with late-adult-onset ulcerative colitis have better outcomes than those with early onset disease
    Christina Y Ha
    Division of Gastroenterology, Washington University in St Louis School of Medicine, St Louis, Missouri 63110, USA
    Clin Gastroenterol Hepatol 8:682-687.e1. 2010

Collaborators

Detail Information

Publications12

  1. pmc Indoleamine 2,3 dioxygenase in intestinal disease
    Matthew A Ciorba
    Division of Gastroenterology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Curr Opin Gastroenterol 29:146-52. 2013
    ..Promotion of T-cell-mediated tolerance and antimicrobial effects are among the variety of functions attributed to IDO1 activity. Recent advances addressing the diverse implications of gut-associated IDO1 expression are herein reviewed...
  2. pmc A gastroenterologist's guide to probiotics
    Matthew A Ciorba
    Department of Medicine, Division of Gastroenterology, Washington University, St Louis School of Medicine, St Louis, Missouri 63110, USA
    Clin Gastroenterol Hepatol 10:960-8. 2012
    ..The current review provides condition-specific rationale for using probiotic therapy and literature-based recommendations...
  3. pmc Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner
    Matthew A Ciorba
    Division of Gastroenterology, Washington University Saint Louis, 660 South Euclid Avenue, Box 8124, Saint Louis, MO 63110, USA
    Gut 61:829-38. 2012
    ..The small intestinal epithelium is highly sensitive to radiation and is a major site of injury during radiation therapy and environmental overexposure...
  4. pmc IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice
    Ameet I Thaker
    Division of Gastroenterology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Gastroenterology 145:416-25.e1-4. 2013
    ..We used genetic and pharmacologic approaches to manipulate IDO1 activity in mice with colitis-associated cancer and human colon cancer cell lines...
  5. pmc Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity
    Nitin K Gupta
    Division of Gastroenterology, Washington University in Saint Louis School of Medicine, St Louis, Missouri, USA
    Inflamm Bowel Dis 18:1214-20. 2012
    ..We sought to determine if increased gut expression of IDO1 in Crohn's disease (CD) would result in detectable changes in serum levels of tryptophan and the initial IDO1 pathway catabolite, kynurenine...
  6. pmc Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis
    Matthew A Ciorba
    Division of Gastroenterology, Washington University, St Louis, MO 63110, USA
    J Immunol 184:3907-16. 2010
    ..These findings support the possibility that targeted induction of IDO-1 is an approach deserving further investigation as a therapeutic strategy for diseases of intestinal inflammation...
  7. doi request reprint Microbial influences on the small intestinal response to radiation injury
    Christopher D Packey
    Division of Gastroenterology, Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA
    Curr Opin Gastroenterol 26:88-94. 2010
    ..Here, we will review recent developments in the area of acute radiation enteropathy and examine the current state of knowledge regarding the impact of host-microbial interactions in the process...
  8. pmc Biomarkers in inflammatory bowel disease: current practices and recent advances
    Heba N Iskandar
    Division of Gastroenterology, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA
    Transl Res 159:313-25. 2012
    ..This article reviews the uses and limitations of currently available biomarkers and highlights recent advances in IBD biomarker discovery...
  9. doi request reprint Probiotics as therapy in gastroenterology: a study of physician opinions and recommendations
    Michael D Williams
    Saint Louis University School of Medicine, St Louis, MO 63110, USA
    J Clin Gastroenterol 44:631-6. 2010
    ..The objective of this study was to determine how gastroenterologists perceive and use probiotic-based therapies in practice...
  10. pmc Patients with late-adult-onset ulcerative colitis have better outcomes than those with early onset disease
    Christina Y Ha
    Division of Gastroenterology, Washington University in St Louis School of Medicine, St Louis, Missouri 63110, USA
    Clin Gastroenterol Hepatol 8:682-687.e1. 2010
    ..Given potential age-related differences in risk factors and immune function, we sought to determine if disease behavior or clinical outcomes differed between patients diagnosed with UC in later versus earlier stages of adulthood...
  11. doi request reprint Magnetic resonance enterography: safe and effective imaging for stricturing Crohn's disease
    Christina Y Ha
    Division of Gastroenterology, Washington University in St Louis School of Medicine, St Louis, MO 63110, USA
    Dig Dis Sci 56:2906-13. 2011
    ..Magnetic resonance enterography (MRE) provides information regarding disease activity, chronicity, and stricture formation without using ionizing radiation...
  12. doi request reprint Probiotic therapy in radiation-induced intestinal injury and repair
    Matthew A Ciorba
    Division of Gastroenterology, Washington University in Saint Louis School of Medicine, Saint Louis, MO 63110, USA
    Ann N Y Acad Sci 1165:190-4. 2009
    ..We will review the area with a focus on new developments surrounding probiotic therapy in radiation-induced intestinal injury and repair...