Research Topics
| THEODORE CICEROSummaryAffiliation: Washington University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Health outcomes in patients using no-prescription online pharmacies to purchase prescription drugsTheodore J Cicero
School of Medicine, Department of Psychiatry, Washington University in St Louis, Saint Louis, MO 63110, USA
J Med Internet Res 14:e174. 2012..Many prescription drugs are freely available for purchase on the Internet without a legitimate prescription from a physician...
Trends in the use and abuse of branded and generic extended release oxycodone and fentanyl products in the United StatesTheodore J Cicero
Washington University School of Medicine, Department of Psychiatry, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110 1093, USA
Drug Alcohol Depend 91:115-20. 2007..In this paper we assessed whether the introduction of generic products in the U.S. increased the therapeutic use and illicit abuse of extended release oxycodone products and the fentanyl patch...- Trends in abuse of Oxycontin and other opioid analgesics in the United States: 2002-2004Theodore J Cicero
Washington University School of Medicine, St Louis, Missouri 63110, USA
J Pain 6:662-72. 2005.... - Rates of abuse of tramadol remain unchanged with the introduction of new branded and generic products: results of an abuse monitoring system, 1994-2004Theodore J Cicero
Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
Pharmacoepidemiol Drug Saf 14:851-9. 2005..This provided a unique opportunity to study the potential changes in abuse as the generic and combination products became available... - Relationship between therapeutic use and abuse of opioid analgesics in rural, suburban, and urban locations in the United StatesTheodore J Cicero
Washington University School of Medicine, MO, USA
Pharmacoepidemiol Drug Saf 16:827-40. 2007..The goal of these studies was to determine the relationship between prescribed use of opioid analgesics and their non-medically related use (abuse) at a regional level across the country... - Co-morbid pain and psychopathology in males and females admitted to treatment for opioid analgesic abuseTheodore J Cicero
Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110 1093, USA
Pain 139:127-35. 2008.... - Source of drugs for prescription opioid analgesic abusers: a role for the Internet?Theodore J Cicero
Departmentof Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
Pain Med 9:718-23. 2008..We have studied whether this is correct... 
Co-morbidity and utilization of medical services by pain patients receiving opioid medications: data from an insurance claims databaseTheodore J Cicero
Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
Pain 144:20-7. 2009..g. morphine and oxycodone) seemed to be driven by numerous factors not necessarily related to the intensity or duration of pain...- Determinants of fentanyl and other potent µ opioid agonist misuse in opioid-dependent individualsTheodore J Cicero
Department of Psychiatry, Washington University, St Louis, MO 63110, USA
Pharmacoepidemiol Drug Saf 19:1057-63. 2010..Since the latter is seldom true, we postulated that there would be a significant mismatch between actual and predicted rates of misuse... - Role of key informants and direct patient interviews in epidemiological studies of substance abuseTheodore J Cicero
Washington University in St Louis, Department of Psychiatry, St Louis, MO, USA
Pharmacoepidemiol Drug Saf 20:308-12. 2011..The present study was undertaken to assess the degree to which key informants' perceptions of relative abuse liability of opioids in their communities correspond to actual drug use in their patients... - The development of a comprehensive risk-management program for prescription opioid analgesics: researched abuse, diversion and addiction-related surveillance (RADARS)Theodore J Cicero
Washington University School of Medicine, St Louis, Missouri 63110, USA
Pain Med 8:157-70. 2007..Thus, its major focus was the detection of abuse of OxyContin and other commonly prescribed opioid analgesics at the three-digit ZIP code level across the country utilizing a number of different detection systems... - Patterns of prescription opioid abuse and comorbidity in an aging treatment populationTheodore J Cicero
Washington University Department of Psychiatry, Campus Box 8134, 660 S Euclid Avenue, St Louis MO 63110, USA
J Subst Abuse Treat 42:87-94. 2012..Our results indicate that a "one-size-fits-all" approach to prevention, intervention, and treatment of opioid abuse that ignores the shifting needs of opioid-abusing men and women as they age is destined to fail... - Use and misuse of buprenorphine in the management of opioid addictionTheodore J Cicero
Washington University School of Medicine, St Louis, Missouri, USA
J Opioid Manag 3:302-8. 2007..Thus, the results indicate that it is unlikely that buprenorphine abuse will ever reach the epidemic that was feared by some regulatory groups and that its use in opioid detoxification and maintenance should continue... - Role of steroids in sex differences in morphine-induced analgesia: activational and organizational effectsTheodore J Cicero
Washington University School of Medicine, Department of Psychiatry, St Louis, Missouri 63110, USA
J Pharmacol Exp Ther 300:695-701. 2002.... - Chronic opiate exposure in the male rat adversely affects fertilityTheodore J Cicero
Department of Psychiatry, Washington University School of Medicine, Box 8027, 660 South Euclid Avenue, St Louis, MO 63110 1093, USA
Pharmacol Biochem Behav 72:157-63. 2002..This potentially important effect of paternal morphine administration on conception and/or preimplementation loss of embryos has not been previously noted and deserves more systematic study... - Gender-linked differences in the expression of physical dependence in the ratTheodore J Cicero
Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, St Louis, MO 63110, USA
Pharmacol Biochem Behav 72:691-7. 2002.... - Gender differences in the intravenous self-administration of mu opiate agonistsTheodore J Cicero
Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, St Louis, MO 63110, USA
Pharmacol Biochem Behav 74:541-9. 2003..Finally, we conclude that they will also expend much greater effort in an operant conditioning task to obtain opiate reinforcement... - Chronic morphine increases the pituitary-adrenocortical response of juvenile rats to mild stressBruce Nock
Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
Pharmacol Biochem Behav 80:77-85. 2005..Either way, there is a striking shift in morphine's effects on the pituitary-adrenocortical axis across development... - Foundations of opioid risk managementNathaniel P Katz
Tufts University School of Medicine, Boston, MA, USA
Clin J Pain 23:103-18. 2007..Limitations of current approaches, and emerging directions in opioid risk management, are also presented... - Physical dependence on Ultram (tramadol hydrochloride): both opioid-like and atypical withdrawal symptoms occurEdward C Senay
Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA
Drug Alcohol Depend 69:233-41. 2003..These results indicate that physicians and other healthcare professionals need to be aware of the potential of Ultram to induce withdrawal of the classical opioid type, and that atypical withdrawal may also occur... - Postmarketing surveillance for drug abuseCynthia L Arfken
Department of Psychiatry and Behavioral Neurosciences, School of Medicine, Wayne State University, 2761 E Jefferson, Detroit, MI 48207, USA
Drug Alcohol Depend 70:S97-105. 2003..Information on comparator medications is highly recommended both to validate the system and to place the results in context... - An independent assessment of MEDWatch reporting for abuse/dependence and withdrawal from Ultram (tramadol hydrochloride)George E Woody
Treatment Research Institute, School of Medicine, Philadelphia Va University of Pennsylvania, 600 Public Ledger Building, 150 South Independence Mall W, Philadelphia, PA 19106 3475, USA
Drug Alcohol Depend 72:163-8. 2003..Assess the validity of medical products reporting program (MEDWatch) reports of abuse/dependence and withdrawal associated with Ultram (tramadol)... - Diversion and abuse of methadone prescribed for pain managementTheodore J Cicero
JAMA 293:297-8. 2005 - Mechanisms of prescription drug diversion among drug-involved club- and street-based populationsJames A Inciardi
Center for Drug and Alcohol Studies, University of Delaware, Coral Gables, Florida 33134, USA
Pain Med 8:171-83. 2007..However, empirical data on diversion are limited... - A comparison of the abuse liability of tramadol, NSAIDs, and hydrocodone in patients with chronic painEdgar H Adams
Edgar Adams Consulting, Covance, Princeton, New Jersey 08540, USA
J Pain Symptom Manage 31:465-76. 2006.... - The Diversion of Ultram, Ultracet, and generic tramadol HCLJames A Inciardi
University of Delaware Research Center, Coral Gables, FL 33134, USA
J Addict Dis 25:53-8. 2006..Survey data suggest that the diversion of Ultram and other tramadol products is low, and overall, diversion investigators did not consider tramadol to be a problem in their respective jurisdictions... - Potential for abuse of buprenorphine in office-based treatment of opioid dependenceTheodore J Cicero
N Engl J Med 353:1863-5. 2005
Research Grants
- OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTSTHEODORE CICERO; Fiscal Year: 1992
- Electronic Research Submission at Washington UnivTHEODORE CICERO; Fiscal Year: 2002..In addition, this infrastructure will make it possible for all compliance committees to share data to ensure the highest level of human subject protection. ..
- OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTSTHEODORE CICERO; Fiscal Year: 2003..The proposed animal studies could establish whether gender differences exist and if these differences are based on inherent, first-order biological differences between the sexes. ..
- BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSETHEODORE CICERO; Fiscal Year: 2007....
- BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSETHEODORE CICERO; Fiscal Year: 2006..abstract_text> ..
- OPIATE-ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTSTHEODORE CICERO; Fiscal Year: 1993....
- Molecular Genetics of Inattention in AustraliaTHEODORE CICERO; Fiscal Year: 2009..This will be at a marked cost savings due to the employment of existing well-characterized samples and the long history of collaborative studies between investigators from Australia and the United States. ..