THEODORE CICERO

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Factors contributing to the rise of buprenorphine misuse: 2008-2013
    Theodore J Cicero
    Washington University, Department of Psychiatry, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, United States Electronic address
    Drug Alcohol Depend 142:98-104. 2014
  2. ncbi request reprint Factors influencing the selection of hydrocodone and oxycodone as primary opioids in substance abusers seeking treatment in the United States
    Theodore J Cicero
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA Electronic address
    Pain 154:2639-48. 2013
  3. pmc Health outcomes in patients using no-prescription online pharmacies to purchase prescription drugs
    Theodore J Cicero
    School of Medicine, Department of Psychiatry, Washington University in St Louis, Saint Louis, MO 63110, USA
    J Med Internet Res 14:e174. 2012
  4. ncbi request reprint Trends in the use and abuse of branded and generic extended release oxycodone and fentanyl products in the United States
    Theodore J Cicero
    Washington University School of Medicine, Department of Psychiatry, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110 1093, USA
    Drug Alcohol Depend 91:115-20. 2007
  5. ncbi request reprint Relationship between therapeutic use and abuse of opioid analgesics in rural, suburban, and urban locations in the United States
    Theodore J Cicero
    Washington University School of Medicine, MO, USA
    Pharmacoepidemiol Drug Saf 16:827-40. 2007
  6. ncbi request reprint Trends in abuse of Oxycontin and other opioid analgesics in the United States: 2002-2004
    Theodore J Cicero
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Pain 6:662-72. 2005
  7. ncbi request reprint Rates of abuse of tramadol remain unchanged with the introduction of new branded and generic products: results of an abuse monitoring system, 1994-2004
    Theodore J Cicero
    Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Pharmacoepidemiol Drug Saf 14:851-9. 2005
  8. doi request reprint Co-morbid pain and psychopathology in males and females admitted to treatment for opioid analgesic abuse
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110 1093, USA
    Pain 139:127-35. 2008
  9. doi request reprint Source of drugs for prescription opioid analgesic abusers: a role for the Internet?
    Theodore J Cicero
    Departmentof Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pain Med 9:718-23. 2008
  10. pmc Co-morbidity and utilization of medical services by pain patients receiving opioid medications: data from an insurance claims database
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Pain 144:20-7. 2009

Research Grants

  1. OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1991
  2. OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1992
  3. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2001
  4. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2002
  5. Electronic Research Submission at Washington Univ
    THEODORE CICERO; Fiscal Year: 2002
  6. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2003
  7. BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSE
    THEODORE CICERO; Fiscal Year: 2007
  8. BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSE
    THEODORE CICERO; Fiscal Year: 2006
  9. OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1990
  10. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1999

Detail Information

Publications29

  1. ncbi request reprint Factors contributing to the rise of buprenorphine misuse: 2008-2013
    Theodore J Cicero
    Washington University, Department of Psychiatry, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, United States Electronic address
    Drug Alcohol Depend 142:98-104. 2014
    ..The purpose of the present study was to examine the motivations underlying the use of buprenorphine outside of therapeutic channels and the factors that might account for the reported rapid increase in buprenorphine misuse in recent years...
  2. ncbi request reprint Factors influencing the selection of hydrocodone and oxycodone as primary opioids in substance abusers seeking treatment in the United States
    Theodore J Cicero
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA Electronic address
    Pain 154:2639-48. 2013
    ....
  3. pmc Health outcomes in patients using no-prescription online pharmacies to purchase prescription drugs
    Theodore J Cicero
    School of Medicine, Department of Psychiatry, Washington University in St Louis, Saint Louis, MO 63110, USA
    J Med Internet Res 14:e174. 2012
    ..Many prescription drugs are freely available for purchase on the Internet without a legitimate prescription from a physician...
  4. ncbi request reprint Trends in the use and abuse of branded and generic extended release oxycodone and fentanyl products in the United States
    Theodore J Cicero
    Washington University School of Medicine, Department of Psychiatry, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110 1093, USA
    Drug Alcohol Depend 91:115-20. 2007
    ..In this paper we assessed whether the introduction of generic products in the U.S. increased the therapeutic use and illicit abuse of extended release oxycodone products and the fentanyl patch...
  5. ncbi request reprint Relationship between therapeutic use and abuse of opioid analgesics in rural, suburban, and urban locations in the United States
    Theodore J Cicero
    Washington University School of Medicine, MO, USA
    Pharmacoepidemiol Drug Saf 16:827-40. 2007
    ..The goal of these studies was to determine the relationship between prescribed use of opioid analgesics and their non-medically related use (abuse) at a regional level across the country...
  6. ncbi request reprint Trends in abuse of Oxycontin and other opioid analgesics in the United States: 2002-2004
    Theodore J Cicero
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Pain 6:662-72. 2005
    ..These results indicate that OxyContin abuse is a pervasive problem in this country, but that it needs to be considered in the context of a general pattern of increasing prescription drug abuse...
  7. ncbi request reprint Rates of abuse of tramadol remain unchanged with the introduction of new branded and generic products: results of an abuse monitoring system, 1994-2004
    Theodore J Cicero
    Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Pharmacoepidemiol Drug Saf 14:851-9. 2005
    ..This provided a unique opportunity to study the potential changes in abuse as the generic and combination products became available...
  8. doi request reprint Co-morbid pain and psychopathology in males and females admitted to treatment for opioid analgesic abuse
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110 1093, USA
    Pain 139:127-35. 2008
    ....
  9. doi request reprint Source of drugs for prescription opioid analgesic abusers: a role for the Internet?
    Theodore J Cicero
    Departmentof Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pain Med 9:718-23. 2008
    ..We have studied whether this is correct...
  10. pmc Co-morbidity and utilization of medical services by pain patients receiving opioid medications: data from an insurance claims database
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Pain 144:20-7. 2009
    ..g. morphine and oxycodone) seemed to be driven by numerous factors not necessarily related to the intensity or duration of pain...
  11. pmc Determinants of fentanyl and other potent ยต opioid agonist misuse in opioid-dependent individuals
    Theodore J Cicero
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA
    Pharmacoepidemiol Drug Saf 19:1057-63. 2010
    ..Since the latter is seldom true, we postulated that there would be a significant mismatch between actual and predicted rates of misuse...
  12. pmc Role of key informants and direct patient interviews in epidemiological studies of substance abuse
    Theodore J Cicero
    Washington University in St Louis, Department of Psychiatry, St Louis, MO, USA
    Pharmacoepidemiol Drug Saf 20:308-12. 2011
    ..The present study was undertaken to assess the degree to which key informants' perceptions of relative abuse liability of opioids in their communities correspond to actual drug use in their patients...
  13. ncbi request reprint The development of a comprehensive risk-management program for prescription opioid analgesics: researched abuse, diversion and addiction-related surveillance (RADARS)
    Theodore J Cicero
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pain Med 8:157-70. 2007
    ..Thus, its major focus was the detection of abuse of OxyContin and other commonly prescribed opioid analgesics at the three-digit ZIP code level across the country utilizing a number of different detection systems...
  14. pmc Patterns of prescription opioid abuse and comorbidity in an aging treatment population
    Theodore J Cicero
    Washington University Department of Psychiatry, Campus Box 8134, 660 S Euclid Avenue, St Louis MO 63110, USA
    J Subst Abuse Treat 42:87-94. 2012
    ..Our results indicate that a "one-size-fits-all" approach to prevention, intervention, and treatment of opioid abuse that ignores the shifting needs of opioid-abusing men and women as they age is destined to fail...
  15. ncbi request reprint Use and misuse of buprenorphine in the management of opioid addiction
    Theodore J Cicero
    Washington University School of Medicine, St Louis, Missouri, USA
    J Opioid Manag 3:302-8. 2007
    ..Thus, the results indicate that it is unlikely that buprenorphine abuse will ever reach the epidemic that was feared by some regulatory groups and that its use in opioid detoxification and maintenance should continue...
  16. ncbi request reprint Role of steroids in sex differences in morphine-induced analgesia: activational and organizational effects
    Theodore J Cicero
    Washington University School of Medicine, Department of Psychiatry, St Louis, Missouri 63110, USA
    J Pharmacol Exp Ther 300:695-701. 2002
    ....
  17. ncbi request reprint Chronic opiate exposure in the male rat adversely affects fertility
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, Box 8027, 660 South Euclid Avenue, St Louis, MO 63110 1093, USA
    Pharmacol Biochem Behav 72:157-63. 2002
    ..This potentially important effect of paternal morphine administration on conception and/or preimplementation loss of embryos has not been previously noted and deserves more systematic study...
  18. ncbi request reprint Gender-linked differences in the expression of physical dependence in the rat
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, St Louis, MO 63110, USA
    Pharmacol Biochem Behav 72:691-7. 2002
    ....
  19. ncbi request reprint Gender differences in the intravenous self-administration of mu opiate agonists
    Theodore J Cicero
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, St Louis, MO 63110, USA
    Pharmacol Biochem Behav 74:541-9. 2003
    ..Finally, we conclude that they will also expend much greater effort in an operant conditioning task to obtain opiate reinforcement...
  20. ncbi request reprint Chronic morphine increases the pituitary-adrenocortical response of juvenile rats to mild stress
    Bruce Nock
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Pharmacol Biochem Behav 80:77-85. 2005
    ..Either way, there is a striking shift in morphine's effects on the pituitary-adrenocortical axis across development...
  21. ncbi request reprint Physical dependence on Ultram (tramadol hydrochloride): both opioid-like and atypical withdrawal symptoms occur
    Edward C Senay
    Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA
    Drug Alcohol Depend 69:233-41. 2003
    ..These results indicate that physicians and other healthcare professionals need to be aware of the potential of Ultram to induce withdrawal of the classical opioid type, and that atypical withdrawal may also occur...
  22. ncbi request reprint Postmarketing surveillance for drug abuse
    Cynthia L Arfken
    Department of Psychiatry and Behavioral Neurosciences, School of Medicine, Wayne State University, 2761 E Jefferson, Detroit, MI 48207, USA
    Drug Alcohol Depend 70:S97-105. 2003
    ..Information on comparator medications is highly recommended both to validate the system and to place the results in context...
  23. ncbi request reprint An independent assessment of MEDWatch reporting for abuse/dependence and withdrawal from Ultram (tramadol hydrochloride)
    George E Woody
    Treatment Research Institute, School of Medicine, Philadelphia Va University of Pennsylvania, 600 Public Ledger Building, 150 South Independence Mall W, Philadelphia, PA 19106 3475, USA
    Drug Alcohol Depend 72:163-8. 2003
    ..Assess the validity of medical products reporting program (MEDWatch) reports of abuse/dependence and withdrawal associated with Ultram (tramadol)...
  24. ncbi request reprint Diversion and abuse of methadone prescribed for pain management
    Theodore J Cicero
    JAMA 293:297-8. 2005
  25. ncbi request reprint A comparison of the abuse liability of tramadol, NSAIDs, and hydrocodone in patients with chronic pain
    Edgar H Adams
    Edgar Adams Consulting, Covance, Princeton, New Jersey 08540, USA
    J Pain Symptom Manage 31:465-76. 2006
    ....
  26. ncbi request reprint The Diversion of Ultram, Ultracet, and generic tramadol HCL
    James A Inciardi
    University of Delaware Research Center, Coral Gables, FL 33134, USA
    J Addict Dis 25:53-8. 2006
    ..Survey data suggest that the diversion of Ultram and other tramadol products is low, and overall, diversion investigators did not consider tramadol to be a problem in their respective jurisdictions...
  27. pmc Mechanisms of prescription drug diversion among drug-involved club- and street-based populations
    James A Inciardi
    Center for Drug and Alcohol Studies, University of Delaware, Coral Gables, Florida 33134, USA
    Pain Med 8:171-83. 2007
    ..However, empirical data on diversion are limited...
  28. ncbi request reprint Foundations of opioid risk management
    Nathaniel P Katz
    Tufts University School of Medicine, Boston, MA, USA
    Clin J Pain 23:103-18. 2007
    ..Limitations of current approaches, and emerging directions in opioid risk management, are also presented...
  29. ncbi request reprint Potential for abuse of buprenorphine in office-based treatment of opioid dependence
    Theodore J Cicero
    N Engl J Med 353:1863-5. 2005

Research Grants24

  1. OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1991
  2. OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1992
  3. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2001
    ..The proposed animal studies could establish whether gender differences exist and if these differences are based on inherent, first-order biological differences between the sexes. ..
  4. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2002
    ..The proposed animal studies could establish whether gender differences exist and if these differences are based on inherent, first-order biological differences between the sexes. ..
  5. Electronic Research Submission at Washington Univ
    THEODORE CICERO; Fiscal Year: 2002
    ..In addition, this infrastructure will make it possible for all compliance committees to share data to ensure the highest level of human subject protection. ..
  6. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 2003
    ..The proposed animal studies could establish whether gender differences exist and if these differences are based on inherent, first-order biological differences between the sexes. ..
  7. BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSE
    THEODORE CICERO; Fiscal Year: 2007
    ....
  8. BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSE
    THEODORE CICERO; Fiscal Year: 2006
    ..abstract_text> ..
  9. OPIATE-ENDOCRINE INTERACTIONS; DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1990
  10. OPIATE ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1999
    ..The proposed animal studies could establish whether gender differences exist and if these differences are based on inherent, first-order biological differences between the sexes. ..
  11. OPIATE-ENDOCRINE INTERACTIONS--DEVELOPMENTAL ASPECTS
    THEODORE CICERO; Fiscal Year: 1993
    ....
  12. Molecular Genetics of Inattention in Australia
    THEODORE CICERO; Fiscal Year: 2009
    ..This will be at a marked cost savings due to the employment of existing well-characterized samples and the long history of collaborative studies between investigators from Australia and the United States. ..