RICHARD ARTHUR CHOLE

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. doi request reprint Predictors of future success in otolaryngology residency applicants
    Richard A Chole
    Department of Otolaryngology Head and NeckSurgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 138:707-12. 2012
  2. doi request reprint A novel transnasal transsphenoidal speculum: a design for both microscopic and endoscopic transsphenoidal pituitary surgery
    Richard A Chole
    Department of Otolaryngology, Washington University School of Medicine, St Louis, Missouri, USA
    J Neurosurg 114:1380-5. 2011
  3. ncbi request reprint Evidence for microbial biofilms in cholesteatomas
    Richard A Chole
    Department of Otolaryngology, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 128:1129-33. 2002
  4. doi request reprint Two ears and two (or more?) devices: a pediatric case study of bilateral profound hearing loss
    Rosalie M Uchanski
    Program in Audiology and Communication Sciences, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA
    Trends Amplif 13:107-23. 2009
  5. ncbi request reprint Anatomical evidence of microbial biofilms in tonsillar tissues: a possible mechanism to explain chronicity
    Richard A Chole
    Department of Otolaryngology Head and Neck Surgery, Washington University in St Louis, St Louis, MO, USA
    Arch Otolaryngol Head Neck Surg 129:634-6. 2003
  6. ncbi request reprint Relief of idiopathic subjective tinnitus: is gabapentin effective?
    Jay F Piccirillo
    Division of Clinical Outcomes Research, Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 133:390-7. 2007
  7. ncbi request reprint Bacterial biofilms may explain chronicity in osteoradionecrosis of the temporal bone
    Robert Nason
    Department of Otolaryngology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Otol Neurotol 28:1026-8. 2007
  8. ncbi request reprint Gerbilline cholesteatoma development Part III. Increased proliferation index of basal keratinocytes of the tympanic membrane and external ear canal
    Steven P Tinling
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, University of California Davis, Otolaryngology Research Laboratory, 1515 Newton Court, Davis, CA 95616, USA
    Otolaryngol Head Neck Surg 135:116-23. 2006
  9. doi request reprint Gentian violet and ferric ammonium citrate disrupt Pseudomonas aeruginosa biofilms
    Eric W Wang
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA
    Laryngoscope 118:2050-6. 2008
  10. ncbi request reprint Gerbilline cholesteatoma development. Part II: temporal histopathologic changes in the tympanic membrane and middle ear
    Steven P Tinling
    Department of Otolaryngology Head and Neck Surgery, University of California, Davis, School of Medicine, Davis, California 95616, USA
    Otolaryngol Head Neck Surg 134:953-60. 2006

Research Grants

  1. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD CHOLE; Fiscal Year: 2007
  2. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD CHOLE; Fiscal Year: 2002
  3. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD ARTHUR CHOLE; Fiscal Year: 2010

Collaborators

Detail Information

Publications16

  1. doi request reprint Predictors of future success in otolaryngology residency applicants
    Richard A Chole
    Department of Otolaryngology Head and NeckSurgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 138:707-12. 2012
    ..To evaluate the information available about otolaryngology residency applicants for factors that may predict future success as an otolaryngologist...
  2. doi request reprint A novel transnasal transsphenoidal speculum: a design for both microscopic and endoscopic transsphenoidal pituitary surgery
    Richard A Chole
    Department of Otolaryngology, Washington University School of Medicine, St Louis, Missouri, USA
    J Neurosurg 114:1380-5. 2011
    ..A forehead headrest component adds further stabilization. This device has been used successfully in 90 transsphenoidal procedures...
  3. ncbi request reprint Evidence for microbial biofilms in cholesteatomas
    Richard A Chole
    Department of Otolaryngology, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 128:1129-33. 2002
    ..Additionally, the keratin "matrix" of a cholesteatoma is an ideal environment for the support of biofilm formation...
  4. doi request reprint Two ears and two (or more?) devices: a pediatric case study of bilateral profound hearing loss
    Rosalie M Uchanski
    Program in Audiology and Communication Sciences, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA
    Trends Amplif 13:107-23. 2009
    ..The authors find that although the use of bilateral hearing aids with a CI may only provide a slight benefit, careful attention must be paid to the coordinated fitting of devices, especially at the ear with two devices...
  5. ncbi request reprint Anatomical evidence of microbial biofilms in tonsillar tissues: a possible mechanism to explain chronicity
    Richard A Chole
    Department of Otolaryngology Head and Neck Surgery, Washington University in St Louis, St Louis, MO, USA
    Arch Otolaryngol Head Neck Surg 129:634-6. 2003
    ..The presence of bacterial biofilms within the tissue and crypts of inflamed tonsils may explain the chronicity and recurrent characteristics of some forms of tonsillitis...
  6. ncbi request reprint Relief of idiopathic subjective tinnitus: is gabapentin effective?
    Jay F Piccirillo
    Division of Clinical Outcomes Research, Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 133:390-7. 2007
    ..To assess the therapeutic benefit of gabapentin (Neurontin) for subjective idiopathic troublesome tinnitus...
  7. ncbi request reprint Bacterial biofilms may explain chronicity in osteoradionecrosis of the temporal bone
    Robert Nason
    Department of Otolaryngology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Otol Neurotol 28:1026-8. 2007
    ..To identify biofilm formation within a case of temporal bone osteoradionecrosis...
  8. ncbi request reprint Gerbilline cholesteatoma development Part III. Increased proliferation index of basal keratinocytes of the tympanic membrane and external ear canal
    Steven P Tinling
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, University of California Davis, Otolaryngology Research Laboratory, 1515 Newton Court, Davis, CA 95616, USA
    Otolaryngol Head Neck Surg 135:116-23. 2006
    ..To quantify the rate of basal cell division for keratinizing epithelium (KE) of the tympanic membrane (TM) and external ear canal (EAC) in spontaneous and induced gerbilline cholesteatomas...
  9. doi request reprint Gentian violet and ferric ammonium citrate disrupt Pseudomonas aeruginosa biofilms
    Eric W Wang
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA
    Laryngoscope 118:2050-6. 2008
    ..Gentian violet (GV) and ferric ammonium citrate (FAC) were tested against Pseudomonas aeruginosa biofilms to determine if either substance can reduce biofilm volume...
  10. ncbi request reprint Gerbilline cholesteatoma development. Part II: temporal histopathologic changes in the tympanic membrane and middle ear
    Steven P Tinling
    Department of Otolaryngology Head and Neck Surgery, University of California, Davis, School of Medicine, Davis, California 95616, USA
    Otolaryngol Head Neck Surg 134:953-60. 2006
    ..Determine the sequence of gross and histopathologic change to the normal middle ear (ME), tympanic membrane (TM), and external auditory canal (EAC) during spontaneous gerbilline cholesteatoma development...
  11. ncbi request reprint Gerbilline cholesteatoma development Part I: Epithelial migration pattern and rate on the gerbil tympanic membrane: comparisons with human and guinea pig
    Steven P Tinling
    Department of Otolaryngology Head and Neck Surgery, University of California, Davis, School of Medicine, Davis, California 95616, USA
    Otolaryngol Head Neck Surg 134:788-93. 2006
    ....
  12. ncbi request reprint Otopathogenic Pseudomonas aeruginosa strains as competent biofilm formers
    Eric W Wang
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Otolaryngol Head Neck Surg 131:983-9. 2005
    ..To determine whether Pseudomonas aeruginosa, a common cholesteatoma pathogen, known to form biofilms in other chronic infections, is capable of contributing to biofilm formation in cholesteatoma...
  13. ncbi request reprint A possible role for nitric oxide in osteoclastogenesis associated with cholesteatoma
    Jae Y Jung
    Department of Otolaryngology, Washington University, St Louis, Missouri 63110, USA
    Otol Neurotol 25:661-8. 2004
    ..This study was designed to investigate the potential role of nitric oxide in cholesteatoma-induced bone resorption, in vitro and in vivo...
  14. ncbi request reprint Increased proliferation and migration of epithelium in advancing experimental cholesteatomas
    Hyung Jong Kim
    Department of Otorhinolaryngology, College of Medicine, Hallym University, Anyang, Korea
    Otol Neurotol 23:840-4. 2002
    ..Hyperproliferative and migratory process of keratinocytes are part of the pathogenesis of cholesteatoma...
  15. pmc Expression patterns of cytokeratins in cholesteatomas: evidence of increased migration and proliferation
    Hyung Jong Kim
    Department of Otolaryngology, College of Medicine, Hallym University, Chuncheon, Korea
    J Korean Med Sci 17:381-8. 2002
    ..The findings of this study support the basal cell hyperplasia hypotheses for the pathogenesis of aural cholesteatoma, with regard to hyperproliferation, migration, and an altered differentiation of keratinocytes...
  16. ncbi request reprint Bone resorption in chronic otitis media: the role of the osteoclast
    Jae Y Jung
    Department of Otolaryngology, Washington University, St Louis, MO, USA
    ORL J Otorhinolaryngol Relat Spec 64:95-107. 2002
    ..This review focuses on osteoclast biology, lessons from genetically altered mice, and their contribution to our understanding of cholesteatoma-induced bone resorption...

Research Grants15

  1. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD CHOLE; Fiscal Year: 2007
    ..To study LPS-independent osteoclastogenesis, we will use LPS-insensitive osteoclast precursors derived from mice deficient in toll-like receptor 4 to determine which portions of the osteoclast development pathway are induced. ..
  2. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD CHOLE; Fiscal Year: 2002
    ....
  3. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD ARTHUR CHOLE; Fiscal Year: 2010
    ....