Research Topics
Species | Li Shiun ChenSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Detail Information
Publications
Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genesRichard A Grucza
Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Ave, St Louis, MO 63110, USA
Addict Biol 15:346-57. 2010..Incorporation of logically chosen interaction parameters, such as AOS, into genetic models of substance use disorders may increase the degree of explained phenotypic variation and constitutes a promising avenue for gene discovery...
Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation successLi Shiun Chen
Department of Psychiatry and the Department of Genetics, Washington University School of Medicine, St Louis, MO, USA
Am J Psychiatry 169:735-42. 2012....
Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genesLi Shiun Chen
Department of Psychiatry, Washington University, St Louis, MO 63110, USA
Drug Alcohol Depend 123:S42-51. 2012..We examined whether these genetic variants were associated with comorbid disorders and whether comorbid psychiatric disorders modified the genetic risk of nicotine dependence...
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25Li Shiun Chen
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
Genet Epidemiol 36:340-51. 2012..Using the cross-population study paradigm provides valuable insights to narrow regions of interest and inform future biological experiments...
Dissection of the phenotypic and genotypic associations with nicotinic dependenceLi Shiun Chen
Department of Psychiatry Box 8134, Washington University School of Medicine, 660S Euclid Ave, St Louis, MO 63110, USA
Nicotine Tob Res 14:425-33. 2012..We examined how these identified genetic variants relate to nicotine dependence defined by different categorical and dimensional measures...
Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophreniaLi Shiun Chen
Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
Schizophr Res 111:159-66. 2009....
