KS C CHAO

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi Intensity-modulated radiation therapy in head and neck cancers: The Mallinckrodt experience
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, Missouri, USA
    Int J Cancer 90:92-103. 2000
  2. ncbi Clinical experience of head-and-neck cancer IMRT with serial tomotherapy
    Gokhan Ozyigit
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO 63110, USA
    Med Dosim 27:91-8. 2002
  3. ncbi Intensity-modulated radiation therapy reduces late salivary toxicity without compromising tumor control in patients with oropharyngeal carcinoma: a comparison with conventional techniques
    K S Chao
    Department of Radiation Oncology, Washington University Medical Center, St Louis, MO, USA
    Radiother Oncol 61:275-80. 2001
  4. ncbi Esthesioneuroblastoma: the impact of treatment modality
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, WU Box 8224, 4939 Children s Place, Suite 5500, St Louis, MO 63110, USA
    Head Neck 23:749-57. 2001
  5. ncbi A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 49:1171-82. 2001
  6. ncbi A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 49:907-16. 2001
  7. ncbi Target coverage for head and neck cancers treated with IMRT: review of clinical experiences
    Adam S Garden
    Department of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Semin Radiat Oncol 14:103-9. 2004
  8. ncbi Intensity-modulated radiation therapy for oropharyngeal carcinoma: impact of tumor volume
    K S Clifford Chao
    Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:43-50. 2004
  9. ncbi Determination and delineation of nodal target volumes for head-and-neck cancer based on patterns of failure in patients receiving definitive and postoperative IMRT
    K S Clifford Chao
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 53:1174-84. 2002
  10. ncbi Technology insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning
    Steven J Frank
    University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Nat Clin Pract Oncol 2:526-33. 2005

Collaborators

Detail Information

Publications36

  1. ncbi Intensity-modulated radiation therapy in head and neck cancers: The Mallinckrodt experience
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, Missouri, USA
    Int J Cancer 90:92-103. 2000
    ..Int. J. Cancer (Radiat. Oncol. Invest.) 90, 92-103, (2000)...
  2. ncbi Clinical experience of head-and-neck cancer IMRT with serial tomotherapy
    Gokhan Ozyigit
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO 63110, USA
    Med Dosim 27:91-8. 2002
    ..In this review, we summarize our own IMRT treatment techniques with serial tomotherapy and our clinical experience with 126 patients with head-and-neck IMRT...
  3. ncbi Intensity-modulated radiation therapy reduces late salivary toxicity without compromising tumor control in patients with oropharyngeal carcinoma: a comparison with conventional techniques
    K S Chao
    Department of Radiation Oncology, Washington University Medical Center, St Louis, MO, USA
    Radiother Oncol 61:275-80. 2001
    ..In this study, acute and late toxicity, and tumor control were compared between conventional beam arrangement (CRT) and IMRT...
  4. ncbi Esthesioneuroblastoma: the impact of treatment modality
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, WU Box 8224, 4939 Children s Place, Suite 5500, St Louis, MO 63110, USA
    Head Neck 23:749-57. 2001
    ..We evaluated the impact of treatment modality on esthesioneuroblastoma...
  5. ncbi A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 49:1171-82. 2001
    ....
  6. ncbi A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results
    K S Chao
    Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 49:907-16. 2001
    ..The functional outcome 6 months after the completion of radiation therapy is presented...
  7. ncbi Target coverage for head and neck cancers treated with IMRT: review of clinical experiences
    Adam S Garden
    Department of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Semin Radiat Oncol 14:103-9. 2004
    ..This review will focus on how IMRT is being implemented into the treatment of head and neck cancer, specifically with regards to target definition and dosing issues...
  8. ncbi Intensity-modulated radiation therapy for oropharyngeal carcinoma: impact of tumor volume
    K S Clifford Chao
    Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:43-50. 2004
    ....
  9. ncbi Determination and delineation of nodal target volumes for head-and-neck cancer based on patterns of failure in patients receiving definitive and postoperative IMRT
    K S Clifford Chao
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 53:1174-84. 2002
    ..We present the guidelines for target volume determination and delineation of head-and-neck lymph nodes based on the analysis of the patterns of nodal failure in patients treated with intensity-modulated radiotherapy (IMRT)...
  10. ncbi Technology insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning
    Steven J Frank
    University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Nat Clin Pract Oncol 2:526-33. 2005
    ..The use of PET/CT for staging and detecting both primary and recurrent head and neck cancer is valuable; however, its application in radiation treatment planning should be viewed as investigational...
  11. ncbi Applicator-guided intensity-modulated radiation therapy
    Daniel A Low
    Department of Radiation Oncology, Mallinckrodt Institute, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 52:1400-6. 2002
    ..The flexibility of IMRT will enable customized dose distributions that have the potential to reduce complications and improve local control, especially for locally advanced disease...
  12. ncbi Potential of tomotherapy for total scalp treatment
    Jay Locke
    Mallinckrodt Institute of Radiology, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 52:553-9. 2002
    ..Total scalp radiotherapy is required in a variety of clinical situations. We compared conventional lateral photon-electron (LPE) technique with tomotherapy (intensity-modulated radiotherapy [IMRT])...
  13. ncbi Protection of salivary function by intensity-modulated radiation therapy in patients with head and neck cancer
    K S Clifford Chao
    Radiation Oncology Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Semin Radiat Oncol 12:20-5. 2002
    ..The authors also review existing clinical data on the combination of amifostine and radiation and the potential therapeutic gain in combining IMRT with amifostine...
  14. ncbi Dose-volume modeling of salivary function in patients with head-and-neck cancer receiving radiotherapy
    Angel I Blanco
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 62:1055-69. 2005
    ..The incidence of xerostomia was significantly decreased when the mean dose of at least one parotid gland was kept to < 25.8 Gy with conventional fractionation. However, even lower mean doses imply increased late salivary function...
  15. ncbi Determining optimal clinical target volume margins in head-and-neck cancer based on microscopic extracapsular extension of metastatic neck nodes
    Smith Apisarnthanarax
    Department of Experimental Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 64:678-83. 2006
    ....
  16. ncbi Intensity-modulated radiation therapy in head and neck cancers: an update
    Nancy Lee
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Head Neck 29:387-400. 2007
    ..The results do confirm that IMRT does decrease xerostomia compared with conventional radiotherapy...
  17. ncbi Importance of patient examination to clinical quality assurance in head and neck radiation oncology
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Head Neck 28:967-73. 2006
    ..We determined the value of clinical peer review in radiation therapy for head and neck cancer that involved head and neck examination...
  18. ncbi Additional value of PET/CT over PET in assessment of locoregional lymph nodes in thoracic esophageal squamous cell cancer
    Shuanghu Yuan
    Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan, China
    J Nucl Med 47:1255-9. 2006
    ....
  19. ncbi Effect of regression of enlarged neck lymph nodes on radiation doses received by parotid glands during intensity-modulated radiotherapy for head and neck cancer
    Yu-Cheng Kuo
    Cancer Center and Department of Radiation Oncology, Taipei Medical University Hospital, Taipei, Taiwan
    Am J Clin Oncol 29:600-5. 2006
    ..However, recontouring of large lymph nodes that regress during therapy has a risk of under-dosing extracapsular extension of lymph node metastases. Therefore, recontouring should be done with extreme caution...
  20. ncbi Evaluation of peritumoral edema in the delineation of radiotherapy clinical target volumes for glioblastoma
    Eric L Chang
    Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:144-50. 2007
    ..To evaluate the spatial relationship between peritumoral edema and recurrence pattern in patients with glioblastoma (GBM)...
  21. ncbi Reduce in variation and improve efficiency of target volume delineation by a computer-assisted system using a deformable image registration approach
    K S Clifford Chao
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 7030, USA
    Int J Radiat Oncol Biol Phys 68:1512-21. 2007
    ....
  22. ncbi Comparison of 2D radiographic images and 3D cone beam computed tomography for positioning head-and-neck radiotherapy patients
    Heng Li
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:916-25. 2008
    ..To assess the benefit of patient-specific headrest...
  23. ncbi Toxicity and compliance of subcutaneous amifostine in patients undergoing postoperative intensity-modulated radiation therapy for head and neck cancer
    Wade L Thorstad
    Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA
    Semin Oncol 31:8-12. 2004
    ..Twenty-seven patients have been accrued onto this trial, and the toxicity and compliance data are reported herein...
  24. ncbi Intensity-modulated radiotherapy: is xerostomia still prevalent?
    Mark S Chambers
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Curr Oncol Rep 7:131-6. 2005
    ....
  25. ncbi Current imaging paradigms in radiation oncology
    Smith Apisarnthanarax
    Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Radiat Res 163:1-25. 2005
    ....
  26. ncbi Lymphangiogram-assisted lymph node target delineation for patients with gynecologic malignancies
    K S Clifford Chao
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 54:1147-52. 2002
    ..In this study, assisted by lymphangiography (LAG), we derived guidelines for delineating nodal target volumes on CT...
  27. ncbi Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer
    K S Clifford Chao
    Department of Radiation Oncology, Washington University Medical School, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 55:312-21. 2003
    ..To analyze the patterns of locoregional failure in patients with head-and-neck cancer treated with inverse planning intensity-modulated radiotherapy (IMRT)...
  28. ncbi A conceptual model integrating spatial information to assess target volume coverage for IMRT treatment planning
    K S Clifford Chao
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:1438-49. 2003
    ..This conceptual model is based on the hypothesis that various subregions within a given CTV that may carry different degree of risk in containing microscopic disease...
  29. ncbi Management of nonsinonasal neuroendocrine carcinomas of the head and neck
    Jerry L Barker
    Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 98:2322-8. 2003
    ....
  30. ncbi Intensity-modulated radiation therapy for head and neck cancer
    Gokhan Ozyigit
    Department of Radiation Oncology, University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Curr Treat Options Oncol 5:3-9. 2004
    ..The initial results of clinical IMRT studies showed reduction in xerostomia with no compromise in locoregional control if caution and appropriate knowledge are exercised in target determination and delineation...
  31. ncbi Pilot study of subcutaneous amifostine in patients undergoing postoperative intensity modulated radiation therapy for head and neck cancer: preliminary data
    Wade L Thorstad
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Semin Oncol 30:96-100. 2003
    ....
  32. ncbi Toxicity profile of intensity-modulated radiation therapy for head and neck carcinoma and potential role of amifostine
    K S Clifford Chao
    Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA
    Semin Oncol 30:101-8. 2003
    ..An ongoing trial of concomitant chemotherapy and IMRT with subcutaneous amifostine (Ethyol, WR-2721; MedImmune, Inc, Gaithersburg, MD) for organ function preservation is also discussed...
  33. ncbi A prospective, nonrandomized study of the impact of amifostine on subsequent hypothyroidism in irradiated patients with head and neck cancers
    Imran Zoberi
    Department of Radiation Oncology, Washington University in Saint Louis, St Louis, MO 63110, USA
    Semin Radiat Oncol 12:14-7. 2002
    ..Local control of disease is achieved in many patients who are at risk for late sequelae of treatment that may diminish quality of life...
  34. ncbi Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck
    Jay S Cooper
    New York University Medical Center, New York, USA
    N Engl J Med 350:1937-44. 2004
    ..However, the combined treatment is associated with a substantial increase in adverse effects...
  35. ncbi Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system
    Jerry L Barker
    Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:960-70. 2004
    ..In theory, such a strategy would maximize the therapeutic ratio of RT...
  36. ncbi Potentiation of the immunotherapeutic effect of autologous dendritic cells by pretreating hepatocellular carcinoma with low-dose radiation
    Ching Chung Lin
    Division of Gastroenterology, Mackay Memorial Hospital, Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    Clin Invest Med 31:E150-9. 2008
    ..To determine whether exposing hepatocellular carcinoma (HCC) to low dose radiation increases the efficacy of dendritic cell-mediated immunotherapy for HCC...