Kathleen K Bucholz

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Nosology and epidemiology of addictive disorders and their comorbidity
    K K Bucholz
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychiatr Clin North Am 22:221-40. 1999
  2. ncbi request reprint A latent class analysis of antisocial personality disorder symptom data from a multi-centre family study of alcoholism
    K K Bucholz
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108 1334, USA
    Addiction 95:553-67. 2000
  3. ncbi request reprint Transitions in drinking in adolescent females: evidence from the Missouri adolescent female twin study
    K K Bucholz
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis 63108, USA
    Alcohol Clin Exp Res 24:914-23. 2000
  4. pmc Associations of alcohol, nicotine, cannabis, and drug use/dependence with educational attainment: evidence from cotwin-control analyses
    Julia D Grant
    Midwest Alcoholism Research Center at Washington University, Washington University School of Medicine, St Louis, Missouri, USA
    Alcohol Clin Exp Res 36:1412-20. 2012
  5. pmc A model to determine the likely age of an adolescent's first drink of alcohol
    Samuel Kuperman
    Department of Psychiatry, University of Iowa Carver College of Medicine, 200 Hawkins Dr, RM 1873 JPP, Iowa City, IA 52242, USA
    Pediatrics 131:242-8. 2013
  6. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
  7. pmc Differences in time to onset of smoking and nicotine dependence by race/ethnicity in a Midwestern sample of adolescents and young adults from a high risk family study
    Alexis E Duncan
    The Brown School, Washington University, St Louis, MO 63130, USA
    Drug Alcohol Depend 125:140-5. 2012
  8. pmc Common genetic contributions to alcohol and cannabis use and dependence symptomatology
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 34:545-54. 2010
  9. pmc A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, Missouri 63110, USA
    Biol Psychiatry 64:922-9. 2008
  10. pmc Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 33:2047-56. 2009

Collaborators

Detail Information

Publications114 found, 100 shown here

  1. ncbi request reprint Nosology and epidemiology of addictive disorders and their comorbidity
    K K Bucholz
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychiatr Clin North Am 22:221-40. 1999
    ....
  2. ncbi request reprint A latent class analysis of antisocial personality disorder symptom data from a multi-centre family study of alcoholism
    K K Bucholz
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108 1334, USA
    Addiction 95:553-67. 2000
    ..To determine if there are subtypes of Antisocial Personality Disorder (ASPD), as manifested by distinctive symptom profiles or by associations with alcohol, other drug dependence or other psychiatric disorders...
  3. ncbi request reprint Transitions in drinking in adolescent females: evidence from the Missouri adolescent female twin study
    K K Bucholz
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis 63108, USA
    Alcohol Clin Exp Res 24:914-23. 2000
    ..Data from adult community samples indicate that alcohol dependence originates in late adolescence, thus marking that period as a fruitful one for the study of transitions in drinking...
  4. pmc Associations of alcohol, nicotine, cannabis, and drug use/dependence with educational attainment: evidence from cotwin-control analyses
    Julia D Grant
    Midwest Alcoholism Research Center at Washington University, Washington University School of Medicine, St Louis, Missouri, USA
    Alcohol Clin Exp Res 36:1412-20. 2012
    ..We tested whether alcohol, nicotine, and illicit drug use and dependence were associated with lifetime educational attainment after controlling for familial background characteristics...
  5. pmc A model to determine the likely age of an adolescent's first drink of alcohol
    Samuel Kuperman
    Department of Psychiatry, University of Iowa Carver College of Medicine, 200 Hawkins Dr, RM 1873 JPP, Iowa City, IA 52242, USA
    Pediatrics 131:242-8. 2013
    ..With the use of a new cohort of adolescent subjects, predictors from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) interview and the Achenbach Youth Self Report (YSR) were combined to model age of first drink (AFD)...
  6. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
    ..A high genetic correlation between these measures would suggest that a continuous measure of consumption may have a useful role in the discovery of genes contributing to dependence risk...
  7. pmc Differences in time to onset of smoking and nicotine dependence by race/ethnicity in a Midwestern sample of adolescents and young adults from a high risk family study
    Alexis E Duncan
    The Brown School, Washington University, St Louis, MO 63130, USA
    Drug Alcohol Depend 125:140-5. 2012
    ....
  8. pmc Common genetic contributions to alcohol and cannabis use and dependence symptomatology
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 34:545-54. 2010
    ....
  9. pmc A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, Missouri 63110, USA
    Biol Psychiatry 64:922-9. 2008
    ..The goal of this study was to examine the association of this variant with cocaine dependence...
  10. pmc Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 33:2047-56. 2009
    ..In this study, we examine whether age at first drink moderates genetic and environmental influences, via gene x environment interactions, on DSM-IV alcohol dependence symptoms...
  11. pmc Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO 63106, USA
    Addict Behav 37:240-7. 2012
    ..Smoking interventions may have greatest impact by targeting smoking prevention among peer groups in adolescent and young adult populations...
  12. pmc Transitions to regular smoking and to nicotine dependence in women using cannabis
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 95:107-14. 2008
    ..If there is evidence in its favor, the increased rates of cigarette smoking in cannabis users may prove to be the most significant public health problem associated with cannabis use...
  13. pmc Posttraumatic stress disorder; combat exposure; and nicotine dependence, alcohol dependence, and major depression in male twins
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service, St Louis, MO 63106, USA
    Compr Psychiatry 49:297-304. 2008
    ..These findings suggest comorbid PTSD may represent a genetically mediated vulnerability to psychopathology after trauma...
  14. pmc Multiple-domain predictors of problematic alcohol use in young adulthood
    John R Kramer
    Department of Psychiatry, Medical Education Building, University of Iowa School of Medicine, 500 Newton Road, Iowa City, Iowa 52242 1000, USA
    J Stud Alcohol Drugs 69:649-59. 2008
    ..The goal of this study was to identify predictors of problematic young adult alcohol use...
  15. pmc Predictors of sexual debut at age 16 or younger
    Patricia A Cavazos-Rehg
    Department of Psychiatry, Washington University, Campus Box 8134, 660 South Euclid, St Louis, MO 63110, USA
    Arch Sex Behav 39:664-73. 2010
    ..These results provide evidence that specific variables in the self and familial systems of influence are important in predicting sexual debut at 16 years old or earlier...
  16. pmc Psychiatric and familial predictors of transition times between smoking stages: results from an offspring-of-twins study
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addict Behav 33:235-51. 2008
    ..Findings characterize a rarely examined aspect of the course of ND development and highlight critical distinctions in risk profiles across stages of tobacco involvement...
  17. pmc Contribution of parental psychopathology to offspring smoking and nicotine dependence in a genetically informative design
    Hong Xian
    Research Service 151JC, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, Missouri 63106, USA
    J Stud Alcohol Drugs 71:664-73. 2010
    ....
  18. pmc Early cannabis use and DSM-IV nicotine dependence: a twin study
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Addiction 103:1896-904. 2008
    ..We examine whether cannabis use prior to age 17 years is associated with an increased likelihood of DSM-IV nicotine dependence and the extent to which genetic and environmental factors contribute to this association...
  19. ncbi request reprint Spousal concordance for alcohol dependence: evidence for assortative mating or spousal interaction effects?
    Julia D Grant
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 31:717-28. 2007
    ..The primary goal of the present analyses is to test hypotheses about the source(s) and magnitude of spousal associations for AD using a twin-spouse design...
  20. pmc Drinking motives in female smokers: factor structure, alcohol dependence, and genetic influences
    Sean D Kristjansson
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 35:345-54. 2011
    ....
  21. pmc Smoking outcome expectancies in young adult female smokers: individual differences and associations with nicotine dependence in a genetically informative sample
    Sean D Kristjansson
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 116:37-44. 2011
    ....
  22. pmc A latent class analysis of DSM-IV and Fagerström (FTND) criteria for nicotine dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Nicotine Tob Res 13:972-81. 2011
    ....
  23. ncbi request reprint Teenagers are right--parents do not know much: an analysis of adolescent-parent agreement on reports of adolescent substance use, abuse, and dependence
    Sherri L Fisher
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 30:1699-710. 2006
    ..The purpose of this study was to analyze correspondence between adolescent and parent reports of adolescent substance use and abuse or dependence...
  24. pmc Genetic influences on craving for alcohol
    Arpana Agrawal
    Washington University School of Medicine, Dept of Psychiatry, 660 S Euclid, CB 8134, Saint Louis, MO 63110, USA
    Addict Behav 38:1501-8. 2013
    ..However, little is known of its genetic underpinnings - specifically, whether genetic influences on craving are distinct from those influencing DSM-IV alcohol dependence...
  25. pmc Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression
    Carolyn E Sartor
    Department of Psychiatry, Yale School of Medicine, VA Connecticut Healthcare System, USA
    Arch Gen Psychiatry 69:293-9. 2012
    ....
  26. doi request reprint Genetic and environmental contributions to nicotine, alcohol and cannabis dependence in male twins
    Hong Xian
    Research Service, St Louis Veterans Affairs Medical Center VAMC, St Louis, MO 63106, USA
    Addiction 103:1391-8. 2008
    ..To compute the common and specific genetic and environmental contributions to nicotine dependence (ND) alcohol dependence (AD) and cannabis dependence (CD)...
  27. ncbi request reprint Nicotine dependence subtypes: association with smoking history, diagnostic criteria and psychiatric disorders in 5440 regular smokers from the Vietnam Era Twin Registry
    Hong Xian
    Research Service, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, MO 63106, USA
    Addict Behav 32:137-47. 2007
    ..Empirically derived subtypes of nicotine dependence are mostly characterized by increasing severity. Suggestions for refinement of nicotine dependence diagnostic criteria are discussed...
  28. ncbi request reprint Risk for initiation of substance use as a function of age of onset of cigarette, alcohol and cannabis use: findings in a Midwestern female twin cohort
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Prev Med 43:125-8. 2006
    ..We investigated whether use and early-onset use of cigarettes, alcohol and cannabis contributed an increase in risk for initiation of subsequent psychoactive substances in women (N = 3729, mean age = 21.7)...
  29. ncbi request reprint Childhood sexual abuse and risks for licit and illicit drug-related outcomes: a twin study
    Elliot C Nelson
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Psychol Med 36:1473-83. 2006
    ..This study examined the relationships between self-reported childhood sexual abuse (CSA) and drug-related outcomes in an Australian twin panel...
  30. pmc Differential etiology of posttraumatic stress disorder with conduct disorder and major depression in male veterans
    Qiang Fu
    Department of Community Health, Saint Louis University School of Public Health, St Louis, Missouri 63104, USA
    Biol Psychiatry 62:1088-94. 2007
    ..Epidemiologic studies reveal that posttraumatic stress disorder (PTSD) is highly comorbid with both conduct disorder and major depression in men. The genetic and environmental etiology of this comorbidity has not been examined...
  31. ncbi request reprint Stimulant use and symptoms of abuse/dependence: epidemiology and associations with cannabis use--a twin study
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Rd, Suite 1000, St Louis, MO 63110, United States
    Drug Alcohol Depend 86:147-53. 2007
    ....
  32. pmc Simultaneous cannabis and tobacco use and cannabis-related outcomes in young women
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Drug Alcohol Depend 101:8-12. 2009
    ....
  33. ncbi request reprint Relationship of age of first drink to child behavioral problems and family psychopathology
    Samuel Kuperman
    Department of Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, IA 52242 1057, USA
    Alcohol Clin Exp Res 29:1869-76. 2005
    ....
  34. pmc Understanding adolescent parenthood from a multisystemic perspective
    Patricia A Cavazos-Rehg
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    J Adolesc Health 46:525-31. 2010
    ..This study examined the associations between social, behavioral, and environmental factors and adolescent parenthood...
  35. ncbi request reprint Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychol Med 36:109-18. 2006
    ..Early alcohol use is associated with abuse and dependence of licit and illicit substances later in life. The role of genetic and environmental factors in this association is not conclusive...
  36. pmc Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring
    Vivia V McCutcheon
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8134, St Louis, MO 63110, USA
    Drug Alcohol Depend 128:20-9. 2013
    ..The present study examines the clustering of offspring lifetime substance use and psychiatric disorders into subtypes and characterizes them in terms of familial and non-familial influences using an offspring-of-twins design...
  37. pmc Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol
    Vivia V McCutcheon
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 35:1985-93. 2011
    ..The current study examines differences in alcohol criteria functioning by DUI history and gender using an item response theory (IRT) approach...
  38. doi request reprint Treatment-resistant and insufficiently treated depression and all-cause mortality following myocardial infarction
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 501 North Grand Boulevard, St Louis, MO 63103, USA
    Br J Psychiatry 200:137-42. 2012
    ..Depression is a known risk factor for mortality after an acute myocardial infarction. Patients with treatment-responsive depression may have a better prognosis than those with treatment-resistant depression...
  39. ncbi request reprint Heritability of SF-36 among middle-age, middle-class, male-male twins
    James C Romeis
    Comparative Aging and Health Status Laboratory, Department of Health Management and Policy, School of Public Health, Saint Louis University, St Louis, MO 63104 1314, USA
    Med Care 43:1147-54. 2005
    ....
  40. pmc Childhood sexual abuse and the course of alcohol dependence development: findings from a female twin sample
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Drug Alcohol Depend 89:139-44. 2007
    ..Findings indicate that CSA and elevated risk for AD may be linked via early age at first drink and that progression from first drink to AD follows a similar course among women with and without histories of CSA...
  41. pmc A genome-wide association study of DSM-IV cannabis dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Saint Louis, MO 63110, USA
    Addict Biol 16:514-8. 2011
    ..While replication is required, this study represents an important first step toward clarifying the biological underpinnings of cannabis dependence...
  42. pmc Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample
    Arpana Agrawal
    Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 93:12-20. 2008
    ..0 on chromosome 2 (3.2, 234 cM), 10 (2.4 and 2.6 at 60 cM and 116 cM) and 13 (2.1 at 64 cM). These regions may harbor genes that contribute to the biological basis of alcohol and drug dependence...
  43. ncbi request reprint The relationship between alcohol problems and dependence, conduct problems and diagnosis, and number of sex partners in a sample of young adults
    Patricia A Cavazos-Rehg
    Washington University in St Louis, St Louis, Missouri, USA
    Alcohol Clin Exp Res 31:2046-52. 2007
    ..This study examined the extent to which alcohol dependence and conduct disorder are associated with the number of sexual partners and membership in a risk group of having a high number of sexual partners (10 or more)...
  44. pmc Alcohol criteria endorsement and psychiatric and drug use disorders among DUI offenders: greater severity among women and multiple offenders
    Vivia V McCutcheon
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8134, St Louis, MO 63110 1010, United States
    Addict Behav 34:432-9. 2009
    ....
  45. pmc Peer substance involvement modifies genetic influences on regular substance involvement in young women
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Addiction 105:1844-53. 2010
    ..We examine mechanisms by which PSI influences the etiology of regular substance involvement (RSI), particularly in women...
  46. pmc An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring
    Marc A Schuckit
    Department of Psychiatry, University of California, San Diego, California, USA
    J Stud Alcohol Drugs 70:436-45. 2009
    ..This article presents the first full test of this LR-based model in young subjects from the Collaborative Study on the Genetics of Alcoholism (COGA)...
  47. pmc Initial response to cigarettes predicts rate of progression to regular smoking: findings from an offspring-of-twins design
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, Saint Louis, Missouri 63110, USA
    Addict Behav 35:771-8. 2010
    ..exclusively negative (physiological) responses suggests the importance of considering both dimensions in combination to characterize risk for smoking-related outcomes...
  48. pmc Alcohol use among older adults in the National Epidemiologic Survey on Alcohol and Related Conditions: a latent class analysis
    Paul Sacco
    George Warren Brown School of Social Work, Washington University in St Louis, St Louis, MO, USA
    J Stud Alcohol Drugs 70:829-38. 2009
    ..We examined latent classes of alcohol use among current drinkers ages 60 and older and explored risk factors associated with class...
  49. ncbi request reprint Duration of cannabis use--a novel phenotype?
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Rd, Suite 1000, St Louis, MO 63110, United States
    Addict Behav 31:984-94. 2006
    ..While there were high genetic correlations in both women and men, lifetime duration of cannabis may be uniquely informative in assessing components of liability to cannabis use...
  50. pmc A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA)
    John R Kramer
    Department of Psychiatry, Medical Education Building, University of Iowa School of Medicine, 500 Newton Road, Iowa City, Iowa 52242 1000, USA
    J Stud Alcohol Drugs 70:623-7. 2009
    ....
  51. doi request reprint Correlates of cigarette smoking during pregnancy and its genetic and environmental overlap with nicotine dependence
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Nicotine Tob Res 10:567-78. 2008
    ....
  52. pmc Childhood sexual abuse and early substance use in adolescent girls: the role of familial influences
    Carolyn E Sartor
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Addiction 108:993-1000. 2013
    ..To assess the extent to which the association between childhood sexual abuse (CSA) and early use of alcohol, cigarettes and cannabis in adolescent girls is mediated by risk factors that tend to cluster in families where CSA occurs...
  53. pmc The relationship between rs3779084 in the dopa decarboxylase (DDC) gene and alcohol consumption is mediated by drinking motives in regular smokers
    Sean D Kristjansson
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Alcohol Clin Exp Res 36:162-70. 2012
    ....
  54. pmc Patterns of use, sequence of onsets and correlates of tobacco and cannabis
    Arpana Agrawal
    Washington University School of Medicine, Dept of Psychiatry and the Midwest Alcoholism Research Center, Saint Louis, MO 63110, USA
    Addict Behav 36:1141-7. 2011
    ..In this study, we characterize patterns of cannabis and tobacco use (tobacco but not cannabis, cannabis but not tobacco or both) and compare the factors associated with onset of tobacco before cannabis and cannabis before tobacco...
  55. pmc Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Avenue, Box 8134, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 70:157-68. 2009
    ..The purpose of this study was to develop a quantitative measure of alcohol consumption for gene-mapping studies...
  56. doi request reprint Clinical implications of tolerance to alcohol in nondependent young drinkers
    Marc A Schuckit
    Department of Psychiatry, University of California, San Diego 92161 2002, USA
    Am J Drug Alcohol Abuse 34:133-49. 2008
    ..However, relatively few data are available on the clinical implications of tolerance in nondependent men and women...
  57. ncbi request reprint A twin study of depression symptoms, hypertension, and heart disease in middle-aged men
    Jeffrey F Scherrer
    School of Public Health, St Louis University Health Sciences Center, Missouri, USA
    Psychosom Med 65:548-57. 2003
    ..We utilized a twin design to test whether there are common genetic and environmental risk factors underlying depression symptoms, hypertension and heart disease...
  58. pmc Genetic and environmental influences on the rate of progression to alcohol dependence in young women
    Carolyn E Sartor
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 32:632-8. 2008
    ....
  59. pmc A genome-wide association study of alcohol dependence
    Laura J Bierut
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 107:5082-7. 2010
    ..11 and 1.16. Further dissection of the alcoholism phenotype, to disentangle the influence of comorbid substance-use disorders, will be a next step in identifying genetic variants associated with alcohol dependence...
  60. pmc Common genetic influences on the timing of first use for alcohol, cigarettes, and cannabis in young African-American women
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110, USA
    Drug Alcohol Depend 102:49-55. 2009
    ..Differences in findings may also reflect a distinct etiological pathway for substance use initiation in African-American women that could not be detected in previous studies...
  61. ncbi request reprint Depression increases risk of incident myocardial infarction among Veterans Administration patients with rheumatoid arthritis
    Jeffrey F Scherrer
    Research Service, St Louis Veterans Affairs Medical Center, St Louis, MO 63106, USA
    Gen Hosp Psychiatry 31:353-9. 2009
    ..This study evaluates whether depression is a risk factor for incident myocardial infarction (MI) in Department of Veterans Affairs (VA) patients with rheumatoid arthritis (RA) between 30 and 79 years of age...
  62. pmc Correlates of cannabis initiation in a longitudinal sample of young women: the importance of peer influences
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Prev Med 45:31-4. 2007
    ..In adolescent girls especially, rates of cannabis use have increased over the last decade, urging the need to characterize the potential correlates of onset of cannabis use during emerging adulthood...
  63. ncbi request reprint Subtypes of illicit drug users: a latent class analysis of data from an Australian twin sample
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, United States of America
    Twin Res Hum Genet 9:523-30. 2006
    ..Aggregation of population-level data may obscure important subgroup differences in patterns of illicit drug use and psychiatric comorbidity. Further exploration of a 'self-medicating' subgroup is needed...
  64. pmc A cotwin-control analysis of drug use and abuse/dependence risk associated with early-onset cannabis use
    Julia D Grant
    The Midwest Alcoholism Research Center at Washington University, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addict Behav 35:35-41. 2010
    ..In contrast to previous research, there is limited evidence for increased risk associated with early-onset use in this sample of Vietnam-era veterans...
  65. pmc Correspondence between secular changes in alcohol dependence and age of drinking onset among women in the United States
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 32:1493-501. 2008
    ..The present report sought to confirm the trends in AOD and to determine the extent to which they might account for secular trends in alcohol dependence...
  66. pmc Clustering of trauma and associations with single and co-occurring depression and panic attack over twenty years
    Vivia V McCutcheon
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Twin Res Hum Genet 13:57-65. 2010
    ..Assaultive trauma outweighed associations of familial effects and nonassaultive trauma with risk for 10 years following first trauma...
  67. pmc Posttraumatic stress disorder and alcohol dependence in young women
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 71:810-8. 2010
    ....
  68. pmc Timing of first alcohol use and alcohol dependence: evidence of common genetic influences
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110, USA
    Addiction 104:1512-8. 2009
    ..To estimate the magnitude of genetic and environmental influences on timing of first alcohol use and alcohol dependence (AD) and to quantify the overlap in these influences across the two alcohol-related outcomes...
  69. ncbi request reprint Genetic effects on alcohol dependence risk: re-evaluating the importance of psychiatric and other heritable risk factors
    Valerie S Knopik
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Psychol Med 34:1519-30. 2004
    ..Genetic influences have been shown to play a major role in determining the risk of alcohol dependence (AD) in both women and men; however, little attention has been directed to identifying the major sources of genetic variation in AD risk...
  70. ncbi request reprint Assortative mating for cigarette smoking and for alcohol consumption in female Australian twins and their spouses
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, 8134, St Louis, MO 63110, USA
    Behav Genet 36:553-66. 2006
    ..We aim to clarify the mechanisms contributing to spousal similarity for cigarette smoking and alcohol consumption...
  71. pmc Correlates of alcohol abuse/dependence in early-onset alcohol-using women
    Mitchell B Jenkins
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Am J Addict 20:429-34. 2011
    ....
  72. ncbi request reprint Age at first sexual intercourse and teenage pregnancy in Australian female twins
    Mary Waldron
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, United States of America
    Twin Res Hum Genet 10:440-9. 2007
    ....
  73. pmc Alcohol dependence and reproductive onset: findings in two Australian twin cohorts
    Mary Waldron
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 32:1865-74. 2008
    ..We examine the relationship between lifetime history of alcohol dependence (AD) and timing of first childbirth across reproductive development...
  74. pmc A principal components analysis of the abbreviated Desires for Alcohol Questionnaire (DAQ)
    John R Kramer
    Department of Psychiatry, Medical Education Building, University of Iowa School of Medicine, 500 Newton Road, Iowa City, Iowa 52242 1000, USA
    J Stud Alcohol Drugs 71:150-5. 2010
    ..The aim of this study was to examine the abbreviated Desires for Alcohol Questionnaire (DAQ) with respect to component structure and concurrent validity...
  75. ncbi request reprint Early-onset alcohol-use behaviors and subsequent alcohol-related driving risks in young women: a twin study
    Michael T Lynskey
    Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Road, Suite 1000, Saint Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 68:798-804. 2007
    ..The purpose of this study was to estimate associations between early-onset alcohol use/intoxication and subsequent risks of alcohol-related driving risks in young women after control for familial liability for these behaviors...
  76. ncbi request reprint Association between self-reported childhood sexual abuse and adverse psychosocial outcomes: results from a twin study
    Elliot C Nelson
    Washington University School of Medicine, Department of Psychiatry, 40 N Kingshighway, Suite 1, St Louis, MO 63108, USA
    Arch Gen Psychiatry 59:139-45. 2002
    ..Increased risk for serious adverse outcomes has been associated with a history of childhood sexual abuse (CSA). Whether these risks are directly attributable to CSA rather than family background remains controversial...
  77. ncbi request reprint Paternal alcohol dependence and offspring suicidal behaviors in a children-of-twins study
    Anne L Glowinski
    Department of Psychiatry, Box 8134, Washington University School of Medicine, 40 North Kingshighway, Suite One, St Louis, MO 63108, USA
    Drug Alcohol Depend 76:S69-77. 2004
    ..The children-of-twins (COT) design can be used to elucidate the association of a parental trait and an offspring outcome such as the association of parental alcoholism and offspring suicidality...
  78. pmc Alcohol and tobacco use disorders in a general population: short-term and long-term associations from the St. Louis epidemiological catchment area study
    Kristina M Jackson
    Department of Psychological Sciences, University of Missouri, Columbia, 200 South Seventh Street, Columbia, MO 65211, USA
    Drug Alcohol Depend 71:239-53. 2003
    ..The AUD-TD association was prospectively examined using data from the St. Louis Epidemiological Catchment Area (ECA) Study and its 1-year follow-up as well as from a 16-year follow-up on a subsample of ECA data...
  79. ncbi request reprint Defining nicotine dependence for genetic research: evidence from Australian twins
    Christina N Lessov
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Psychol Med 34:865-79. 2004
    ....
  80. ncbi request reprint Shared genetic risk of major depression, alcohol dependence, and marijuana dependence: contribution of antisocial personality disorder in men
    Qiang Fu
    Missouri Alcoholism Research Center at Washington University, Department of Psychiatry, Washington University School of Medicine, 40 N Kingshighway Blvd, Suite 2, St Louis, MO 63108, USA
    Arch Gen Psychiatry 59:1125-32. 2002
    ..We examined the contribution of genetic effects associated with ASPD to the comorbidity of MD and substance use disorders...
  81. ncbi request reprint The relationship between parental alcoholism and adolescent psychopathology: a systematic examination of parental comorbid psychopathology
    Christine McCauley Ohannessian
    Department of Individual and Family Studies, University of Delaware, Newark, DE 19716, USA
    J Abnorm Child Psychol 32:519-33. 2004
    ..These findings underscore the importance of considering parental comorbid psychopathology when examining the relationship between parental alcoholism and offspring adjustment...
  82. ncbi request reprint Genes, environment, and individual differences in alcohol expectancies among female adolescents and young adults
    Wendy S Slutske
    Missouri Alcoholism Research Center, Department of Psychological Sciences, University of Missouri Columbia, 65211, USA
    Psychol Addict Behav 16:308-17. 2002
    ..The extent to which the familial similarity for positive alcohol expectancies was moderated by age, race, drinking status, and the sharing of peer groups was also examined...
  83. ncbi request reprint Major depressive disorder, suicidal ideation, and suicide attempt in twins discordant for cannabis dependence and early-onset cannabis use
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Arch Gen Psychiatry 61:1026-32. 2004
    ..Previous research has reported both a moderate degree of comorbidity between cannabis dependence and major depressive disorder (MDD) and that early-onset cannabis use is associated with increased risks for MDD...
  84. pmc Genetic epidemiology of self-reported lifetime DSM-IV major depressive disorder in a population-based twin sample of female adolescents
    Anne L Glowinski
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63108, USA
    J Child Psychol Psychiatry 44:988-96. 2003
    ..The goal of this study was the genetic analysis of MDD in an epidemiologically and genetically representative sample of adolescent female twins...
  85. ncbi request reprint Drinking course in alcohol-dependent men from adolescence to midlife
    Carolyn E Sartor
    Department of Veterans Affairs, Palo Alto Health Care System, 795 Willow Road, MC 151 J, Menlo Park, California 94025, USA
    J Stud Alcohol 64:712-9. 2003
    ..g., first alcoholic drink) as well as frequency and duration of periods of abstinence, alcohol dependence (AD) and nonproblem drinking...
  86. ncbi request reprint Escalation of drug use in early-onset cannabis users vs co-twin controls
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    JAMA 289:427-33. 2003
    ..Previous studies have reported that early initiation of cannabis (marijuana) use is a significant risk factor for other drug use and drug-related problems...
  87. ncbi request reprint Are substance use, abuse and dependence associated with study participation? Predictors of offspring nonparticipation in a twin-family study
    Jeffrey F Scherrer
    Research Service 151 JC, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, Missouri 63106, USA
    J Stud Alcohol 65:140-4. 2004
    ..In the current study we constructed a model of offspring nonparticipation in a twin-family design and computed weights to recapture the distribution of offspring alcohol abuse and dependence...
  88. ncbi request reprint Age and birth cohort effects on rates of alcohol dependence
    John P Rice
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 27:93-9. 2003
    ..This suggests additional influences of birth cohort or period effects so that individuals in later-born cohorts have an increased lifetime risk...
  89. ncbi request reprint Genetic and environmental effects on offspring alcoholism: new insights using an offspring-of-twins design
    Theodore Jacob
    Palo Alto Veterans Affairs Health Care System, Menlo Park, CA 94025, USA
    Arch Gen Psychiatry 60:1265-72. 2003
    ....
  90. ncbi request reprint Predictors and correlates of suicide attempts over 5 years in 1,237 alcohol-dependent men and women
    Ulrich W Preuss
    VA San Diego Healthcare System and the University of California, San Diego, CA, USA
    Am J Psychiatry 160:56-63. 2003
    ..Psychiatric comorbidity was examined in terms of a distinction between substance-induced and independent psychiatric disorders...
  91. ncbi request reprint Limitations of DSM-IV operationalizations of alcohol abuse and dependence in a sample of Australian twins
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Twin Res Hum Genet 8:574-84. 2005
    ....
  92. ncbi request reprint Prospective evaluation of the four DSM-IV criteria for alcohol abuse in a large population
    Marc A Schuckit
    VA San Diego Healthcare System, University of California, San Diego, CA, USA
    Am J Psychiatry 162:350-60. 2005
    ....
  93. ncbi request reprint A comparison of the latent class structure of cannabis problems among adult men and women who have used cannabis repeatedly
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 101:1133-42. 2006
    ..Current evidence is not conclusive regarding gender differences for cannabis use, abuse and dependence. It is not known if symptom profiles differ by gender...
  94. pmc Secular trends in the lifetime prevalence of alcohol dependence in the United States: a re-evaluation
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 32:763-70. 2008
    ..However, it remains unclear whether such patterns truly reflect secular trends or are confounded by age-dependent factors such as differential recall, differential mortality, and other effects...
  95. doi request reprint Drinking expectancies and motives: a genetic study of young adult women
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Addiction 103:194-204. 2008
    ..However, little is known of the extent to which genetic and environmental influences contribute to individual differences in expectancies and motives...
  96. pmc Childhood sexual abuse moderates genetic influences on age at first consensual sexual intercourse in women
    Mary Waldron
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Campus Box 8134, St Louis, MO 63110, USA
    Behav Genet 38:1-10. 2008
    ..For both female and male twins, results from models that included conduct disorder as a covariate were near identical to results from models without conduct disorder...
  97. ncbi request reprint Genetic and environmental influences on extreme personality dispositions in adolescent female twins
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Child Psychol Psychiatry 47:902-9. 2006
    ....
  98. ncbi request reprint Evidence for specificity of transmission of alcohol and nicotine dependence in an offspring of twins design
    Heather E Volk
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 87:225-32. 2007
    ..Despite the substantial genetic overlap between the two disorders, there is evidence for genetic effects specific for AD and ND...
  99. ncbi request reprint A latent class analysis of illicit drug abuse/dependence: results from the National Epidemiological Survey on Alcohol and Related Conditions
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 102:94-104. 2007
    ..We examine the co-occurrence of abuse/dependence across different illicit drugs and test associations between these classes and major psychiatric disorders...
  100. ncbi request reprint Transitions to, and correlates of, suicidal ideation, plans, and unplanned and planned suicide attempts among 3,729 men and women with alcohol dependence
    Kenneth R Conner
    Center for the Study and Prevention of Suicide and the Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, New York 14620, USA
    J Stud Alcohol Drugs 68:654-62. 2007
    ....
  101. ncbi request reprint Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk
    Danielle M Dick
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Addiction 102:1131-9. 2007
    ....