Elizabeth M Brunt

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Hepatology 53:810-20. 2011
  2. ncbi request reprint Histopathology of non-alcoholic fatty liver disease
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Box 8118, St Louis, MO 63110, USA
    Clin Liver Dis 13:533-44. 2009
  3. pmc Histopathology of nonalcoholic fatty liver disease
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8118, St Louis, MO 63110, United States
    World J Gastroenterol 16:5286-96. 2010
  4. ncbi request reprint Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    Hum Pathol 35:1070-82. 2004
  5. pmc Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet
    Joel R Garbow
    Department of 1Medicine, Washington University, St Louis, Missouri 63110, USA
    Am J Physiol Gastrointest Liver Physiol 300:G956-67. 2011
  6. ncbi request reprint Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    Brent A Neuschwander-Tetri
    University Liver Center, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, 3635 Vista Avenue, St Louis, MO 63110, USA
    Hepatology 38:1008-17. 2003
  7. pmc Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients
    Sarah L George
    Department of Internal Medicine, Division of Gastroenterology, Saint Louis University Liver Center, St Louis, MO, USA
    Hepatology 49:729-38. 2009
  8. pmc Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Hepatology 49:809-20. 2009
  9. pmc Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease
    Brent A Neuschwander-Tetri
    Saint Louis University School of Medicine, St Louis, MO, USA
    Hepatology 52:913-24. 2010
  10. ncbi request reprint Effect of significant histologic steatosis or steatohepatitis on response to antiviral therapy in patients with chronic hepatitis C
    Stephen A Harrison
    Saint Louis University Liver Center, Saint Louis University, St Louis, MS, USA
    Clin Gastroenterol Hepatol 3:604-9. 2005

Detail Information

Publications64

  1. pmc Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Hepatology 53:810-20. 2011
    ..Higher values of the NAS were associated with higher levels of alanine aminotransferase and aspartate aminotransferase, whereas the diagnosis of SH was associated with features of the metabolic syndrome...
  2. ncbi request reprint Histopathology of non-alcoholic fatty liver disease
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Box 8118, St Louis, MO 63110, USA
    Clin Liver Dis 13:533-44. 2009
    ..This review will focus on the findings in human disease...
  3. pmc Histopathology of nonalcoholic fatty liver disease
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8118, St Louis, MO 63110, United States
    World J Gastroenterol 16:5286-96. 2010
    ..In this review, the rationale for liver biopsy, as well as the histopathological lesions, the microscopically observable patterns of injury, and the differential diagnoses of NAFLD and NASH are discussed...
  4. ncbi request reprint Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    Hum Pathol 35:1070-82. 2004
    ....
  5. pmc Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet
    Joel R Garbow
    Department of 1Medicine, Washington University, St Louis, Missouri 63110, USA
    Am J Physiol Gastrointest Liver Physiol 300:G956-67. 2011
    ..The distinctive nutrient milieu created by long-term administration of this low-carbohydrate, low-protein ketogenic diet in mice evokes unique signatures of nonalcoholic fatty liver disease and whole-body glucose homeostasis...
  6. ncbi request reprint Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    Brent A Neuschwander-Tetri
    University Liver Center, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, 3635 Vista Avenue, St Louis, MO 63110, USA
    Hepatology 38:1008-17. 2003
    ....
  7. pmc Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients
    Sarah L George
    Department of Internal Medicine, Division of Gastroenterology, Saint Louis University Liver Center, St Louis, MO, USA
    Hepatology 49:729-38. 2009
    ..No patient had conclusive evidence of virologic relapse. Three patients had persistently elevated alanine aminotransferase levels; two of these had new liver disease...
  8. pmc Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Hepatology 49:809-20. 2009
    ..0001). In the pediatric biopsies, "more than mild" was associated with steatosis location (P = 0.0008) and fibrosis score (P < 0.0001), specifically, the portal/periportal fibrosis or greater fibrosis) (P < 0.01)...
  9. pmc Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease
    Brent A Neuschwander-Tetri
    Saint Louis University School of Medicine, St Louis, MO, USA
    Hepatology 52:913-24. 2010
    ..70-0.79), and better for advanced fibrosis (AUROC 0.73-0.85)...
  10. ncbi request reprint Effect of significant histologic steatosis or steatohepatitis on response to antiviral therapy in patients with chronic hepatitis C
    Stephen A Harrison
    Saint Louis University Liver Center, Saint Louis University, St Louis, MS, USA
    Clin Gastroenterol Hepatol 3:604-9. 2005
    ..The aim of this study was to evaluate SVR in patients with CHC plus steatosis or SH on biopsy examination, compared with a group of controls with CHC and no significant steatosis or SH...
  11. pmc Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease
    Anping Chen
    Department of Pathology, School of Medicine, Saint Louis University, St Louis, MO, USA
    Hepatology 57:2202-12. 2013
    ..In addition, TFF-fed L-FABP(-/-) mice exhibited decreased hepatic fibrosis, with reduced expression of fibrogenic genes, compared to WT mice...
  12. ncbi request reprint Pathology of nonalcoholic fatty liver disease
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Nat Rev Gastroenterol Hepatol 7:195-203. 2010
    ..Clinical advantages as well as potential drawbacks of liver biopsy are presented. Current pathophysiologic concepts relevant to histologic findings are discussed...
  13. ncbi request reprint Diabetic hepatosclerosis: a 10-year autopsy series
    Guilan Chen
    Department of Pathology, Saint Louis University School of Medicine, St Louis, MO, USA
    Liver Int 29:1044-50. 2009
    ..Diabetic hepatosclerosis (DHS), recently described in liver biopsies in insulin-dependent diabetes mellitus, is characterized by dense perisinusoidal collagen...
  14. ncbi request reprint SALL4 immunoreactivity predicts prognosis in Western hepatocellular carcinoma patients but is a rare event: a study of 236 cases
    Ta Chiang Liu
    Departments of Pathology and Immunology Surgery, Washington University School of Medicine, Saint Louis, MO
    Am J Surg Pathol 38:966-72. 2014
    ..87 mo; P=0.0018). Although SALL4 immunoreactivity in Western HCC is correlated with higher grade and poor prognosis, this is a rare event. Therefore, universal application of SALL4 as a biomarker for HCC should be performed with caution...
  15. pmc Hepatic progenitor cell proliferation and liver injury in α-1-antitrypsin deficiency
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    J Pediatr Gastroenterol Nutr 51:626-30. 2010
    ..However, the mechanisms linking hepatocellular injury to these responses are poorly understood. In this study, we examined liver injury and response in human liver and in transgenic mice for involvement of hepatic progenitor cells...
  16. pmc Excess mortality in patients with advanced chronic hepatitis C treated with long-term peginterferon
    Adrian M Di Bisceglie
    Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St Louis, MO, USA
    Hepatology 53:1100-8. 2011
    ..No specific cause of death accounted for the excess mortality and only one death was suspected to be a direct complication of peginterferon...
  17. pmc Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet
    Rebecca C Schugar
    Department of Medicine, Center for Cardiovascular Research, Washington University, St Louis, Missouri, USA
    PLoS ONE 8:e74806. 2013
    ....
  18. ncbi request reprint Nonalcoholic steatohepatitis
    Elizabeth M Brunt
    Saint Louis University Liver Center, Saint Louis University Health Sciences Center, Department of Pathology, St Louis, Missouri 63110, USA
    Semin Liver Dis 24:3-20. 2004
    ....
  19. ncbi request reprint Evolution of hepatitis C viral quasispecies after liver transplantation
    Andre C Lyra
    Division of Gastroenterology and Hepatology, Department of Internal Medicine and Saint Louis University Liver Center, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    Gastroenterology 123:1485-93. 2002
    ..To determine whether HCV quasispecies diversity correlated positively with liver disease progression after orthotopic liver transplantation (OLT)...
  20. ncbi request reprint Benign hepatocellular tumors (adenomatosis) in nonalcoholic steatohepatitis: a case report
    Elizabeth M Brunt
    Saint Louis University Liver Center, Saint Louis University Health Sciences Center, St Louis, Missouri 63110, USA
    Semin Liver Dis 25:230-6. 2005
  21. ncbi request reprint Short- and long-term outcomes after steatotic liver transplantation
    M B Majella Doyle
    Department of Surgery, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Arch Surg 145:653-60. 2010
    ..To determine if the use of steatotic grafts adversely affects outcomes in liver transplantation...
  22. ncbi request reprint Microscopic margins and patterns of treatment failure in resected pancreatic adenocarcinoma
    Jennifer L Gnerlich
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Arch Surg 147:753-60. 2012
    ..To correlate microscopic margin status with survival and local control in a large cohort of patients from a high-volume pancreatic cancer center...
  23. ncbi request reprint Hepatocyte senescence in end-stage chronic liver disease: a study of cyclin-dependent kinase inhibitor p21 in liver biopsies as a marker for progression to hepatocellular carcinoma
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, St Louis, MO 63110, USA
    Liver Int 27:662-71. 2007
    ..Histologic markers to predict hepatocellular carcinoma (HCC) include small cell change and dysplastic nodules. Hepatocyte senescence is noted in chronic liver disease and may or may not be important in progression to HCC...
  24. doi request reprint Parenchymal alterations in cirrhotic livers in patients with hepatopulmonary syndrome or portopulmonary hypertension
    Changqing Ma
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Liver Transpl 19:741-50. 2013
    ....
  25. ncbi request reprint Diabetic hepatosclerosis: diabetic microangiopathy of the liver
    Stephen A Harrison
    Liver Center, Department of Medicine, Saint Louis University School of Medicine, St Louis, MO 63110, USA
    Arch Pathol Lab Med 130:27-32. 2006
    ..After observing a noncirrhotic form of hepatic sinusoidal fibrosis in patients with long-standing diabetes mellitus who underwent liver biopsy, we set about to characterize this novel entity...
  26. pmc Jaundice: an important, poorly recognized risk factor for diminished survival in patients with adenocarcinoma of the head of the pancreas
    Steven M Strasberg
    Section of Hepato Pancreato Biliary Surgery, Department of Surgery, Washington University in St Louis, St Louis, MO, USA Alvin J Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA
    HPB (Oxford) 16:150-6. 2014
    ..The purpose of this study was to determine whether there is an association between preoperative jaundice and survival in patients who have undergone resection of such tumours...
  27. ncbi request reprint Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease
    Elizabeth M Brunt
    Saint Louis University Liver Center Department of Pathology, Saint Louis University Health Sciences Center, St Louis, Missouri, USA
    Mod Pathol 16:49-56. 2003
    ..Diabetes was reported in 35%, 25%, and 9%. The concurrence of clinical and histologic features of steatohepatitis with another chronic liver disease may be a reflection of the frequency of steatohepatitis in the population at large...
  28. pmc Hepatic expression of cell death-inducing DFFA-like effector C in obese subjects is reduced by marked weight loss
    Angela M Hall
    Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Obesity (Silver Spring) 18:417-9. 2010
    ..Moreover, the hepatic expression of CIDEC is downregulated by marked weight loss...
  29. doi request reprint Validation of organ procurement and transplant network (OPTN)/united network for organ sharing (UNOS) criteria for imaging diagnosis of hepatocellular carcinoma
    Kathryn J Fowler
    Diagnostic Radiology, Washington University, St Louis, MO 63110, USA
    Transplantation 95:1506-11. 2013
    ..The purpose of this retrospective study is to evaluate the validity of the new Organ Procurement and Transplant Network (OPTN) classification system on patients undergoing transplantation for HCC...
  30. pmc Radiologic and intraoperative detection of need for mesenteric vein resection in patients with adenocarcinoma of the head of the pancreas
    Matthew R Porembka
    Section of Hepato Pancreato Biliary Surgery, Department of Surgery, Barnes Jewish Hospital and Washington University in St Louis, St Louis, MO 63110, USA
    HPB (Oxford) 13:633-42. 2011
    ..A single-centre review was performed to determine how efficient these processes are in evaluating the need for MVR...
  31. pmc Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent
    Laura H Tetri
    Department of Internal Medicine, Saint Louis University, MO, USA
    Am J Physiol Gastrointest Liver Physiol 295:G987-95. 2008
    ..Because dietary trans fats promoted liver steatosis and injury, their role in the epidemic of NASH needs further evaluation...
  32. ncbi request reprint Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis
    Brent A Neuschwander-Tetri
    Department of Internal Medicine, Saint Louis University Liver Center, Saint Louis University School of Medicine, 3635 Vista Avenue, St Louis, MO 63110, USA
    J Hepatol 38:434-40. 2003
    ....
  33. ncbi request reprint Alcoholic and nonalcoholic steatohepatitis
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, 4th Floor, SLUH, 3635 Vista Avenue, St Louis, MO 63110, USA
    Clin Liver Dis 6:399-420, vii. 2002
    ..In many instances, however, the microscopic lesions of these two processes are similar, likely as a reflection of common pathogenetic pathways, and the distinction between the two is ultimately clinically derived...
  34. pmc Divergent quasispecies evolution in de novo hepatitis C virus infection associated with bone marrow transplantation
    Weihua Wang
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Biochem Biophys Res Commun 414:148-52. 2011
    ..Instead, our data suggested an essential role of the fitness adaptation of founder viral population in driving such an evolutionary pattern...
  35. ncbi request reprint Orlistat in the treatment of NASH: a case series
    Stephen A Harrison
    Saint Louis University Liver Center, Division of Gastroenterology and Hepatology, St Louis, Missouri 63110, USA
    Am J Gastroenterol 98:926-30. 2003
    ....
  36. doi request reprint Nonalcoholic fatty liver disease: what the pathologist can tell the clinician
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA ebrunt path wustl edu
    Dig Dis 30:61-8. 2012
    ..In addition, pros and cons and recognized limitations of liver biopsy in NAFLD are discussed...
  37. pmc Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts
    Christopher D Anderson
    Departments of Surgery, Washington University, St Louis, MO 63110, USA
    Liver Transpl 17:189-200. 2011
    ..These data confirm ER stress in steatotic allografts and implicate this as a mediating mechanism of inflammation and hepatocyte death in the steatotic liver allograft...
  38. ncbi request reprint Pathological features of NASH
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, St Louis, MO, USA
    Front Biosci 10:1475-84. 2005
    ..While largely focused on adult NAFLD, the manuscript also summarizes what has been reported to date for NAFLD in the pediatric population...
  39. ncbi request reprint Metabolic storage diseases: amyloidosis
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, 4 th Floor, SLUH, 3635 Vista Avenue, St Louis, MO 63110, USA
    Clin Liver Dis 8:915-30, x. 2004
    ..Clinical characteristics and clues to the diagnosis are discussed as well as the importance of histologic confirmation and the controversy surrounding liver biopsy...
  40. ncbi request reprint Liver biopsy diagnosis of hepatitis: clues to clinically-meaningful reporting
    Elizabeth M Brunt
    Washington University School of Medicine in St Louis, USA
    Mo Med 107:113-8. 2010
    ..Processing, protocol stains, and final reporting of findings are discussed...
  41. pmc CD36 deletion reduces VLDL secretion, modulates liver prostaglandins, and exacerbates hepatic steatosis in ob/ob mice
    Fatiha Nassir
    Department of Medicine Washington University School of Medicine, St Louis, MO 63110
    J Lipid Res 54:2988-97. 2013
    ..They provide insight into the association reported in humans between CD36 protein expression and serum levels of apoB and VLDL particle number...
  42. ncbi request reprint Budd-Chiari syndrome and hepatocellular carcinoma: a case report and review of the literature
    Necat Havlioglu
    Department of Pathology, Division of Gastroenterology and Hepatology, Saint Louis University Liver Center, Saint Louis University School of Medicine, St Louis, Missouri 63110 0250, USA
    Am J Gastroenterol 98:201-4. 2003
    ..This case is unusual in two aspects: the patient survived 30 yr after shunt surgery with undiagnosed Budd-Chiari syndrome; and the association of Budd-Chiari syndrome with subsequent hepatocellular carcinoma is uncommon...
  43. ncbi request reprint Expression of P-glycoprotein and C-MOAT in human hepatocellular carcinoma: detection by immunostaining
    John Richart
    Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Dig Dis Sci 47:2454-8. 2002
    ....
  44. ncbi request reprint Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats
    Kyle E Brown
    Gastroenterology Section, John Cochran VAMC, St Louis, MO, USA
    Liver Int 23:232-42. 2003
    ..The aim of this study was to determine the effects of dietary fat of varying PUFA content on iron-induced oxidative stress and fibrosis...
  45. doi request reprint Histopathologic evaluation of liver biopsy for cirrhosis
    Changqing Ma
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Adv Anat Pathol 19:220-30. 2012
    ..This review summarizes liver biopsy findings of cirrhosis and possible etiologies and provides a stepwise approach for the histologic differential diagnosis of a liver biopsy done for "cirrhosis."..
  46. pmc Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects
    Faidon Magkos
    Center for Human Nutrition, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Gastroenterology 142:1444-6.e2. 2012
    ..609; P = .012), but not with intrahepatic ceramide or acylcarnitine. These data indicate that intrahepatic diacylglycerol is an important mediator of hepatic insulin resistance in obese people with nonalcoholic fatty liver disease...
  47. ncbi request reprint Pathology of fatty liver disease
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, St Louis, MO, USA
    Mod Pathol 20:S40-8. 2007
    ..In this review, these concepts as well as the pathophysiologic bases for them are discussed...
  48. ncbi request reprint AAV vector integration sites in mouse hepatocellular carcinoma
    Anthony Donsante
    Department of Internal Medicine, Washington University School of Medicine, Box 8007, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Science 317:477. 2007
    ..Transcripts from adjacent genes encoding snoRNAs and microRNAs were overexpressed in tumors. Our findings implicate this locus in the development of HCC and raise concerns over the clinical use of AAV vectors...
  49. ncbi request reprint Epstein-Barr virus hepatitis: diagnostic value of in situ hybridization, polymerase chain reaction, and immunohistochemistry on liver biopsy from immunocompetent patients
    Namsoo Suh
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Am J Surg Pathol 31:1403-9. 2007
    ..However, EBER-positive cells can be sparse and easily overlooked. Immunohistochemistry for EBV latent membrane proteins apparently has no utility in the diagnosis of EBV hepatitis...
  50. ncbi request reprint Pathology of steatohepatitis
    Elizabeth M Brunt
    Department of Pathology, Saint Louis University School of Medicine, 4th Floor, 3635 Vista Avenue, St Louis, MO 63110, USA
    Best Pract Res Clin Gastroenterol 16:691-707. 2002
    ..This chapter will elucidate the constellation of microscopic findings, the issues of concern for pathological evaluation and the knowledge to date of their significance in various forms of fatty liver disease...
  51. pmc Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice
    Angela M Hall
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    J Lipid Res 51:554-63. 2010
    ..However, whereas perilipin-2 and perilipin-5 levels are primarily regulated posttranslationally, Cide family mRNA expression is induced, suggesting that these families of LDP are controlled at different regulatory checkpoints...
  52. doi request reprint Nonalcoholic fatty liver disease
    Kathryn Law
    Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8118, St Louis, MO 63110, USA
    Clin Liver Dis 14:591-604. 2010
    ..This article describes histologic findings, and provides insights into the pathologic processes and clinical implications across the spectrum of NAFLD...
  53. ncbi request reprint Bone marrow biopsy in patients with hepatitis C virus infection: spectrum of findings and diagnostic utility
    Jeffery M Klco
    Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Am J Hematol 85:106-10. 2010
    ....
  54. ncbi request reprint Pathology of the liver sinusoids
    Elizabeth M Brunt
    Department of Pathology and Immunology, Washington University, School of Medicine, St Louis, MO, USA
    Histopathology 64:907-20. 2014
    ..Pathologists should recognize several patterns of injury involving the sinusoids and surrounding hepatocytes. In this review, injury, alterations and accumulations within the liver sinusoids are illustrated and discussed. ..
  55. ncbi request reprint Noncirrhotic hepatocellular carcinoma: derivation from hepatocellular adenoma? Clinicopathologic analysis
    Ta Chiang Liu
    Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA
    Mod Pathol 27:420-32. 2014
    ....
  56. ncbi request reprint Hepatic iron overload in blacks and whites: a comparative autopsy study
    Kyle E Brown
    John Cochran Veterans Affairs Medical Center, St Louis, Missouri, USA
    Am J Gastroenterol 98:1594-8. 2003
    ..The aim of this study was to compare the prevalence, histological features, and clinical correlates of hepatic iron overload in a group of autopsied black and white veterans...
  57. ncbi request reprint Biliary-venous fistula complicating transjugular intrahepatic portosystemic shunt presenting with recurrent bacteremia, jaundice, anemia and fever
    Qaiser Jawaid
    Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, Saint Louis, MO, USA
    Am J Transplant 3:1604-7. 2003
    ..Liver transplantation may be the preferred treatment if TIPS becomes infected following its complete occlusion...
  58. ncbi request reprint Chemoprevention of hepatocellular carcinoma: use of tamoxifen in an animal model of hepatocarcinogenesis
    Adrian M Di Bisceglie
    Saint Louis University Liver Center, Department of Medicine, Saint Louis University, 3635 Vista Ave at Grand Blvd, MO 63110, USA
    J Lab Clin Med 145:134-8. 2005
    ....
  59. doi request reprint Non-alcoholic fatty liver disease: what's new under the microscope?
    Elizabeth M Brunt
    Department of Pathology, Washington University School of Medicine, St Louis, MO 63110, USA
    Gut 60:1152-8. 2011
    ..Some newly appreciated histopathological findings will be discussed in this review...
  60. doi request reprint Combined hepatocellular-cholangiocarcinoma: what the radiologist needs to know about biphenotypic liver carcinoma
    Anup S Shetty
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8131, Saint Louis, MO, 63110, USA
    Abdom Imaging 39:310-22. 2014
    ..Given the importance of radiological diagnosis, awareness of this tumor type is essential for appropriate management. ..
  61. ncbi request reprint Accelerated hepatic fibrosis in patients with combined hereditary hemochromatosis and chronic hepatitis C infection
    Hari H Diwakaran
    Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, 3635 Vista Avenue, St Louis, Mo 63110 0250, USA
    J Hepatol 36:687-91. 2002
    ..This study determined if HH patients with HCV would present with hepatic fibrosis/cirrhosis at a younger age and at a lower hepatic iron concentration compared to patients with HH or HCV alone...
  62. ncbi request reprint Histological changes after the use of mycophenolate mofetil in autoimmune hepatitis
    Elizabeth M Brunt
    Saint Louis University Liver Center, Saint Louis University Health Sciences Center, St Louis, MO, USA
    Hum Pathol 35:509-12. 2004
    ..Both cytoplasmic features of adaptation and nuclear alterations were noted in hepatocytes. Possible mechanisms for these findings are discussed...
  63. pmc Circulating mesothelin protein and cellular antimesothelin immunity in patients with pancreatic cancer
    Fabian Mc Johnston
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Cancer Res 15:6511-8. 2009
    ..Mesothelin has also been considered as a target for immune-based therapies. We conducted a study on the potential clinical utility of mesothelin as a biomarker for pancreatic disease and therapeutic target pancreatic cancer...
  64. ncbi request reprint A 32-year-old man with hepatitis C who developed progressive liver failure after a bone marrow transplant
    Andre C Lyra
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University School of Medicine, 3635 Vista Ave, St Louis, MO 63110, USA
    Semin Liver Dis 22:103-8. 2002