Daniel C Brennan

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. doi request reprint American Society of Nephrology Quiz and Questionnaire 2012: Transplantation
    Daniel C Brennan
    Renal Division, Washington University, St Louis, Missouri 63110 1010, USA
    Clin J Am Soc Nephrol 8:1267-72. 2013
  2. pmc Racial variation in medical outcomes among living kidney donors
    Krista L Lentine
    Center for Outcomes Research and the Division of Nephrology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    N Engl J Med 363:724-32. 2010
  3. pmc Novel methods for tracking long-term maintenance immunosuppression regimens
    Paula M Buchanan
    Center for Outcomes Research, St Louis University School of Medicine, St Louis, Missouri, USA
    Clin J Am Soc Nephrol 3:117-24. 2008
  4. pmc Early outcomes of thymoglobulin and basiliximab induction in kidney transplantation: application of statistical approaches to reduce bias in observational comparisons
    Lisa M Willoughby
    Department of Research Methodology, Saint Louis University, St Louis, MO 63130, USA
    Transplantation 87:1520-9. 2009
  5. doi request reprint Consistency of racial variation in medical outcomes among publicly and privately insured living kidney donors
    Krista L Lentine
    1 Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 2 Division of Abdominal Transplantation, Department of Surgery, Saint Louis University School of Medicine, St Louis, MO 3 Division of Abdominal Transplantation, Department of Surgery, Dartmouth Hitchcock Medical Center, Hanover, NH 4 Division of Nephrology, Western University, London, Canada 5 Division of Nephrology, Department of Medicine, Washington University School of Medicine, St Louis, MO 6 Division of Abdominal Transplantation, Department of Surgery, Johns Hopkins University, Baltimore, MD 7 Address correspondence to Krista L Lentine, M D, Ph D, Saint Louis University Center for Outcomes Research, Salus Center 4th Floor, 3545 Lafayette Ave, St Louis, MO 63104
    Transplantation 97:316-24. 2014
  6. pmc Increasing incidence of new-onset diabetes after transplant among pediatric renal transplant patients
    Thomas E Burroughs
    Department of Internal Medicine, Center for Outcomes Research, Saint Louis University, 3545 Lafayette Avenue, St Louis, MO 63104, USA
    Transplantation 88:367-73. 2009
  7. doi request reprint Associations of recipient illness history with hypertension and diabetes after living kidney donation
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO, USA
    Transplantation 91:1227-32. 2011
  8. ncbi request reprint Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia
    Daniel L Bohl
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Am J Transplant 5:2213-21. 2005
  9. ncbi request reprint The life-years saved by a deceased organ donor
    Mark A Schnitzler
    Center for Outcomes Research, Department of Medicine, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Am J Transplant 5:2289-96. 2005
  10. ncbi request reprint Influence of early posttransplantation prednisone and calcineurin inhibitor dosages on the incidence of new-onset diabetes
    Thomas E Burroughs
    Center for Outcomes Research, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Clin J Am Soc Nephrol 2:517-23. 2007

Collaborators

Detail Information

Publications63

  1. doi request reprint American Society of Nephrology Quiz and Questionnaire 2012: Transplantation
    Daniel C Brennan
    Renal Division, Washington University, St Louis, Missouri 63110 1010, USA
    Clin J Am Soc Nephrol 8:1267-72. 2013
    ..This article recapitulates the session and reproduces its educational value for a larger audience--that of the readers of the Clinical Journal of the American Society of Nephrology. Have fun...
  2. pmc Racial variation in medical outcomes among living kidney donors
    Krista L Lentine
    Center for Outcomes Research and the Division of Nephrology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    N Engl J Med 363:724-32. 2010
    ..Data regarding health outcomes among living kidney donors are lacking, especially among nonwhite persons...
  3. pmc Novel methods for tracking long-term maintenance immunosuppression regimens
    Paula M Buchanan
    Center for Outcomes Research, St Louis University School of Medicine, St Louis, Missouri, USA
    Clin J Am Soc Nephrol 3:117-24. 2008
    ..This study assessed the accuracy of three potential sources of maintenance immunosuppression data...
  4. pmc Early outcomes of thymoglobulin and basiliximab induction in kidney transplantation: application of statistical approaches to reduce bias in observational comparisons
    Lisa M Willoughby
    Department of Research Methodology, Saint Louis University, St Louis, MO 63130, USA
    Transplantation 87:1520-9. 2009
    ..Retrospective comparison of treatment-related kidney transplant outcomes may be facilitated by multivariable statistical adjustments and case-matching...
  5. doi request reprint Consistency of racial variation in medical outcomes among publicly and privately insured living kidney donors
    Krista L Lentine
    1 Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 2 Division of Abdominal Transplantation, Department of Surgery, Saint Louis University School of Medicine, St Louis, MO 3 Division of Abdominal Transplantation, Department of Surgery, Dartmouth Hitchcock Medical Center, Hanover, NH 4 Division of Nephrology, Western University, London, Canada 5 Division of Nephrology, Department of Medicine, Washington University School of Medicine, St Louis, MO 6 Division of Abdominal Transplantation, Department of Surgery, Johns Hopkins University, Baltimore, MD 7 Address correspondence to Krista L Lentine, M D, Ph D, Saint Louis University Center for Outcomes Research, Salus Center 4th Floor, 3545 Lafayette Ave, St Louis, MO 63104
    Transplantation 97:316-24. 2014
    ..Racial disparities in health outcomes after living donation have been reported, but generalizability is not known...
  6. pmc Increasing incidence of new-onset diabetes after transplant among pediatric renal transplant patients
    Thomas E Burroughs
    Department of Internal Medicine, Center for Outcomes Research, Saint Louis University, 3545 Lafayette Avenue, St Louis, MO 63104, USA
    Transplantation 88:367-73. 2009
    ..Risk of new-onset diabetes after transplant (NODAT) is well characterized for adults but much less understood in pediatric transplant. This study examines the incidence and risk factors of NODAT in pediatric renal transplant patients...
  7. doi request reprint Associations of recipient illness history with hypertension and diabetes after living kidney donation
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO, USA
    Transplantation 91:1227-32. 2011
    ..Little is known about associations of family health history with outcomes after kidney donation...
  8. ncbi request reprint Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia
    Daniel L Bohl
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    Am J Transplant 5:2213-21. 2005
    ..Our data support donor origin for early BKV infection in kidney transplant recipients, and suggest that a specific HLA C locus may be associated with failure to control BKV infection...
  9. ncbi request reprint The life-years saved by a deceased organ donor
    Mark A Schnitzler
    Center for Outcomes Research, Department of Medicine, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Am J Transplant 5:2289-96. 2005
    ..Therefore, increasing organ donation should be considered among our most important public health concerns...
  10. ncbi request reprint Influence of early posttransplantation prednisone and calcineurin inhibitor dosages on the incidence of new-onset diabetes
    Thomas E Burroughs
    Center for Outcomes Research, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Clin J Am Soc Nephrol 2:517-23. 2007
    ..48; P = 0.0012). Whereas the incidence of NOD is greatest with high Tac dosages, the increased risk versus CsA is sustained with lower Tac dosages. Higher steroid dosages increase the early diabetogenic effect of Tac but not of CsA...
  11. doi request reprint Delivery patterns of recommended chronic kidney disease care in clinical practice: administrative claims-based analysis and systematic literature review
    Marie D Philipneri
    Division of Nephrology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Clin Exp Nephrol 12:41-52. 2008
    ..Clinical practice guidelines for management of chronic kidney disease (CKD) have been developed within the Kidney Disease Outcomes Quality Initiative (K/DOQI). Adherence patterns may identify focus areas for quality improvement...
  12. ncbi request reprint Thymoglobulin induction is safe and effective in live-donor renal transplantation: a single center experience
    Karen L Hardinger
    Department of Pharmacy Practice, University of Missouri Kansas City, Kansas City, MO 64108 2792, and Department of Medicine, Barnes Jewish Hospital at Washington University School of Medicine, St Louis, MO, USA
    Transplantation 81:1285-9. 2006
    ..This paper presents observational data of live-donor recipients who received Thymoglobulin induction and standard maintenance immunosuppressive therapy...
  13. pmc Variations in the risk for cerebrovascular events after kidney transplant compared with experience on the waiting list and after graft failure
    Krista L Lentine
    St Louis University Center for Outcomes Research, Salus Center 2nd Floor, 3545 Lafayette Avenue, St Louis, MO 63104, USA
    Clin J Am Soc Nephrol 3:1090-101. 2008
    ..This study examined the risks, predictors, and mortality implications of cerebrovascular disease events after kidney transplantation in a national cohort...
  14. pmc Bariatric surgery among kidney transplant candidates and recipients: analysis of the United States renal data system and literature review
    Kian A Modanlou
    Division of Abdominal Organ Transplantation, Department of Surgery, Saint Louis University Medical Center, St Louis, MO 63130, USA
    Transplantation 87:1167-73. 2009
    ..Limited data exist on the safety and efficacy of bariatric surgery (BS) in patients with kidney failure...
  15. doi request reprint Cardioprotective medication use after acute myocardial infarction in kidney transplant recipients
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Transplantation 91:1120-6. 2011
    ..Limited data are available on the use of potentially cardioprotective medications among U.S. kidney transplant recipients...
  16. pmc Obesity and cardiac risk after kidney transplantation: experience at one center and comprehensive literature review
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Transplantation 86:303-12. 2008
    ..The cardiac implications of obesity in kidney transplant recipients are not well-described...
  17. pmc Cardiac evaluation before kidney transplantation: a practice patterns analysis in Medicare-insured dialysis patients
    Krista L Lentine
    St Louis University Center for Outcomes Research, Salus Center, 2nd Floor, 3545 Lafayette Avenue, St Louis, MO 63104, USA
    Clin J Am Soc Nephrol 3:1115-24. 2008
    ..Evaluation for ischemic heart disease (IHD) is a nonstandardized practice before kidney transplantation. We retrospectively studied pretransplant cardiac evaluation (CE) practices in a national sample of renal allograft recipients...
  18. pmc Incremental value of the pancreas allograft to the survival of simultaneous pancreas-kidney transplant recipients
    Paolo R Salvalaggio
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Diabetes Care 32:600-2. 2009
    ..To quantify the incremental survival benefit of the pancreas allograft in simultaneous pancreas-kidney (SPK) transplant recipients...
  19. ncbi request reprint Five-year follow up of thymoglobulin versus ATGAM induction in adult renal transplantation
    Karen L Hardinger
    Department of Pharmacy, Washington University School of Medicine, St Louis, MO, USA
    Transplantation 78:136-41. 2004
    ..63%), less acute rejection (4% vs. 25%), and better graft survival. This article compares the safety and efficacy of Thymoglobulin versus Atgam induction through 5 years...
  20. ncbi request reprint De novo congestive heart failure after kidney transplantation: a common condition with poor prognostic implications
    Krista L Lentine
    Center for Outcomes Research, Division of Nephrology, Saint Louis University School of Medicine, St Louis, MO, USA
    Am J Kidney Dis 46:720-33. 2005
    ..We aim to describe the risk, predictors, and outcomes associated with de novo congestive heart failure (CHF) after kidney transplantation...
  21. pmc The impact of kidney transplantation on heart failure risk varies with candidate body mass index
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Am Heart J 158:972-82. 2009
    ..The relationship of body mass index (BMI) with heart failure (HF) risk before and after kidney transplant is not well described...
  22. pmc Inhibitory interactions between BK and JC virus among kidney transplant recipients
    Xingxing S Cheng
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    J Am Soc Nephrol 22:825-31. 2011
    ..Donor and recipient JC seropositivity did not predict BK viruria or viremia. In conclusion, among renal transplant recipients, infection with one polyomavirus inversely associates with infection with the other...
  23. doi request reprint Depression diagnoses after living kidney donation: linking U.S. Registry data and administrative claims
    Krista L Lentine
    Saint Louis University Center for Outcomes Research, 3545 Lafayette Ave, St Louis, MO 63104, USA
    Transplantation 94:77-83. 2012
    ..Limited data exist on correlates of psychological outcomes after kidney donation...
  24. ncbi request reprint Cancer diagnoses after living kidney donation: linking U.S. Registry data and administrative claims
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Transplantation 94:139-44. 2012
    ..Mortality records identify cancer as the leading cause of death among living kidney donors, but information on the burden of cancer outside death records is limited in this population...
  25. ncbi request reprint Cyclosporine minimization and cost reduction in renal transplant recipients receiving a C2-monitored, cyclosporine-based quadruple immunosuppressive regimen
    Karen L Hardinger
    Department of Pharmacy, Barnes Jewish Hospital, Washington University, One Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
    Transplantation 78:1198-203. 2004
    ..This trial determines whether lower C2 levels could be targeted safely in de novo kidney transplant recipients under a quadruple regimen compared with a similar cohort monitored with trough (C0) levels...
  26. ncbi request reprint Incidence, predictors, and associated outcomes of atrial fibrillation after kidney transplantation
    Krista L Lentine
    St Louis University Center for Outcomes Research, Salus Center 2nd Floor, 3545 Lafayette Avenue, St Louis, MO 63104, USA
    Clin J Am Soc Nephrol 1:288-96. 2006
    ..Appropriate risk stratification may identify transplant recipients who are in need of close monitoring for and management of this adverse cardiovascular event...
  27. ncbi request reprint Consequences of eliminating HLA-B in deceased donor kidney allocation to increase minority transplantation
    Nzisa Mutinga
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Am J Transplant 5:1090-8. 2005
    ..0%, each producing large cost savings and QALY gains. Policies to increase minority transplants by increasing donation rates may prove more cost effective than the elimination of HLA-B matching from deceased donor kidney allocation...
  28. ncbi request reprint BK virus nephropathy and kidney transplantation
    Daniel L Bohl
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin J Am Soc Nephrol 2:S36-46. 2007
    ..Although no approved antiviral drug is available, leflunomide, cidofovir, quinolones, and intravenous Ig have been used. Retransplantation after BKV nephropathy has been successful...
  29. pmc Serum sickness after treatment with rabbit antithymocyte globulin in kidney transplant recipients with previous rabbit exposure
    Raghavender Boothpur
    Barnes Jewish Hospital, St Louis, MO, USA
    Am J Kidney Dis 55:141-3. 2010
    ..Jaw pain appears to be a hallmark symptom, and treatment with plasmapheresis and steroids relieves symptoms more rapidly than steroids alone...
  30. ncbi request reprint The association of cytomegalovirus sero-pairing with outcomes and costs following cadaveric renal transplantation prior to the introduction of oral ganciclovir CMV prophylaxis
    Mark A Schnitzler
    Pharmaco economic Transplant Research, The Health Administration Program, Washington University School of Medicine, St Louis, Missouri, USA
    Am J Transplant 3:445-51. 2003
    ..The outcomes associated with CMV-seropositive donors and seronegative recipients call for tailored management strategies which may include avoidance of such mismatching, antiviral therapy, immunization, or modified immunosuppression...
  31. ncbi request reprint Agreement of immunosuppression regimens described in Medicare pharmacy claims with the Organ Procurement and Transplantation Network survey
    Paula M Stirnemann
    Saint Louis University Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    J Am Soc Nephrol 17:2299-306. 2006
    ..Low detection rates of OPTN-indicated corticosteroid use within claims require further examination...
  32. ncbi request reprint Incidence and predictors of myocardial infarction after kidney transplantation
    Krista L Lentine
    Saint Louis University Center for Outcomes Research, 3545 Lafayette Avenue, Salus Center, 2nd Floor, St Louis, MO 63104, USA
    J Am Soc Nephrol 16:496-506. 2005
    ..Risk factors for PTMI include potentially modifiable posttransplantation complications. Because PTMI in turn predicts graft failure and death, reducing the risk for PTMI may improve outcomes after kidney transplantation...
  33. ncbi request reprint Long-term outcome of gastrointestinal complications in renal transplant patients treated with mycophenolate mofetil
    Karen L Hardinger
    St Louis College of Pharmacy, St Louis, Missouri, USA
    Transpl Int 17:609-16. 2004
    ....
  34. doi request reprint Obesity and kidney transplant candidates: how big is too big for transplantation?
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Am J Nephrol 36:575-86. 2012
    ..Prospective evaluations of the impact of targeted risk modification efforts in this population including dietary changes, monitored exercise programs, and bariatric surgery are urgently needed...
  35. ncbi request reprint Diabetic complications associated with new-onset diabetes mellitus in renal transplant recipients
    Thomas E Burroughs
    Center for Outcomes Research, Department of Internal Medicine, Saint Louis University, St Louis, MO 63104, USA
    Transplantation 83:1027-34. 2007
    ..Data are scarce regarding the incidence and risk factors for complications of new-onset diabetes mellitus (NODM) in renal transplant patients...
  36. pmc Iron deficiency anemia and iron losses after renal transplantation
    Sijie Zheng
    Department of Internal Medicine, Renal Division, Washington University School of Medicine, St Louis, MO 63110, USA
    Transpl Int 22:434-40. 2009
    ..Blood and iron losses over the first 12 weeks post-transplant are substantial and may warrant early administration of intravenous iron...
  37. ncbi request reprint Mycophenolate mofetil is associated with less death with function than azathioprine in cadaveric renal transplantation
    Mark A Schnitzler
    Pharmaco economic Transplant Research, Washington University School of Medicine, St Louis, MI, USA
    Nephrol Dial Transplant 18:1197-200. 2003
    ..This study was designed to verify this result because methodological issues bring these findings into question...
  38. pmc Sensitivity of billing claims for cardiovascular disease events among kidney transplant recipients
    Krista L Lentine
    Center for Outcomes Research and Division of Nephrology, School of Medicine, Saint Louis University, St Louis, MO 63104, USA
    Clin J Am Soc Nephrol 4:1213-21. 2009
    ..Few studies have described the performance of billing claims as surrogate measures of clinical events among kidney transplant recipients...
  39. ncbi request reprint Early Clinical Complications After ABO-Incompatible Live-Donor Kidney Transplantation: A National Study of Medicare-Insured Recipients
    Krista L Lentine
    1 Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO 2 Division of Abdominal Transplantation, Department of Surgery, Saint Louis University School of Medicine, St Louis, MO 3 Division of Abdominal Transplantation, Department of Surgery, Dartmouth Hitchcock Medical Center, Hanover, NH 4 Transplant Nephrology, Washington University School of Medicine, St Louis, MO 5 Division of Abdominal Transplantation, Department of Surgery, Johns Hopkins University, Baltimore, MD 6 Address correspondence to Krista L Lentine, M D, Ph D, Saint Louis University Center for Outcomes Research, Salus Center 4th Floor, 3545 Lafayette Ave, St Louis, MO 63104
    Transplantation 98:54-65. 2014
    ..Descriptions of the sequelae of ABO-incompatible (ABOi) kidney transplantation are limited to single-center reports, which may lack power to detect important effects...
  40. ncbi request reprint Rabbit antithymocyte globulin versus basiliximab in renal transplantation
    Daniel C Brennan
    Renal Division, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
    N Engl J Med 355:1967-77. 2006
    ..A rabbit antithymocyte polyclonal antibody or basiliximab, an interleukin-2 receptor monoclonal antibody, is most commonly used for induction...
  41. pmc Impact of prophylactic versus preemptive valganciclovir on long-term renal allograft outcomes
    Michael L Spinner
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Transplantation 90:412-8. 2010
    ..Both prophylactic and preemptive oral valganciclovir therapy are effective for the management of cytomegalovirus (CMV) postrenal transplantation in the short term. The long-term effect of either strategy is less well defined...
  42. ncbi request reprint Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction
    Daniel C Brennan
    Washington University School of Medicine, Department of Internal Medicine, St Louis, Missouri, USA
    Am J Transplant 5:582-94. 2005
    ..Viruria was highest with FK506-MMF and lowest with CyA-MMF. Monitoring and preemptive withdrawal of immunosuppression were associated with resolution of viremia and absence of BK nephropathy without acute rejection or graft loss...
  43. ncbi request reprint Cytomegalovirus disease after prophylaxis with oral ganciclovir in renal transplantation: the importance of HLA-DR matching
    Mark A Schnitzler
    Pharmaco economic Transplant Research, The Health Administration Program, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Am Soc Nephrol 14:780-5. 2003
    ..In addition, organ allocation policies discouraging combining CMV-seropositive donors and zero HLA-DR matches may be worth consideration...
  44. ncbi request reprint Cost-effectiveness of extending Medicare coverage of immunosuppressive medications to the life of a kidney transplant
    Eugene F Yen
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA
    Am J Transplant 4:1703-8. 2004
    ..Extended Medicare immunosuppression coverage to the life of a kidney transplant should result in better transplant and economic outcomes, and should be considered by policy makers...
  45. ncbi request reprint Long-term trends in allograft survival
    Daniel C Brennan
    Washington University School of Medicine, St Louis, MO 63110, USA
    Adv Chronic Kidney Dis 13:11-7. 2006
    ..As the short-term complications are prevented or successfully managed, more patients will develop chronic problems with the function of the allograft...
  46. ncbi request reprint Pharmacokinetics of tacrolimus in kidney transplant recipients: twice daily versus once daily dosing
    Karen L Hardinger
    Department of Pharmacy, Barnes Jewish Hospital at Washington University, St Louis, MO, USA
    Am J Transplant 4:621-5. 2004
    ..Tacrolimus given once daily in the morning, at 85% of the twice daily dose, provides safe and equivalent drug exposure to twice daily dosing. This convenient dosing schedule may help to increase compliance and lower costs...
  47. ncbi request reprint A significant role for histocompatibility in human islet transplantation
    T Mohanakumar
    Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Transplantation 82:180-7. 2006
    ..The purpose of this study was to determine the role of pretransplant sensitization to human leukocyte antigen (HLA) in islet transplantation...
  48. ncbi request reprint Current and future immunosuppressive strategies in renal transplantation
    Karen L Hardinger
    Department of Pharmacy, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Pharmacotherapy 24:1159-76. 2004
    ..Allograft tolerance and xenotransplantation are being studied, and the knowledge gained from the effort may help in the development of innovative strategies and new immunosuppressive agents...
  49. ncbi request reprint The expanded criteria donor dilemma in cadaveric renal transplantation
    Mark A Schnitzler
    Health Administration Program, Washington University School of Medicine, St Louis, MO 63110, USA
    Transplantation 75:1940-5. 2003
    ..There is wide variation in opinion concerning the composition of ECD wait lists. However, the relative benefits of accepting an ECD versus waiting for a standard donor have not been quantified...
  50. doi request reprint Induction therapy in renal transplant recipients: how convincing is the current evidence?
    Steven J Wagner
    Renal Division, Washington University in Saint Louis, Saint Louis, MO 63110, USA
    Drugs 72:671-83. 2012
    ..Standardization of definitions and establishment of large, prospective, multicentre trials would lead to a better understanding of the currently available agents and their best use in renal transplantation induction therapy...
  51. ncbi request reprint West Nile virus-associated meningoencephalitis in two chronically immunosuppressed renal transplant recipients
    Karen L Hardinger
    Pharmacy, Barnes Jewish Hospital, Washington University, St Louis, MO, USA
    Am J Transplant 3:1312-5. 2003
    ..Reduction in immunosuppression and supportive care were successful in treating both patients. West Nile meningoencephalitis should be considered in transplant recipients that present with signs and symptoms of meningoencephalitis...
  52. ncbi request reprint Prevention and management of cytomegalovirus infection in solid-organ transplantation
    Kabeya Mwintshi
    Washington University School of Medicine, 660 S Euclid Avenue, Internal Medicine Renal Division, Campus Box 8126, St Louis, MO 63110, USA
    Expert Rev Anti Infect Ther 5:295-304. 2007
    ..Currently, the recommended treatment for CMV disease is intravenous ganciclovir...
  53. ncbi request reprint Prospective, pilot, open-label, short-term study of conversion to leflunomide reverses chronic renal allograft dysfunction
    Karen L Hardinger
    Department of Pharmacy, Barnes Jewish Hospital, Washington University, St Louis, MO, USA
    Am J Transplant 2:867-71. 2002
    ..Mean CyA levels did not change, 146 +/- 72 ng/ mL pre-LEF vs. 132 +/- 51 ng/mL post-LEF, p = NS. Conversion to LEF reversed progression of chronic renal allograft dysfunction with minimal toxicity...
  54. doi request reprint Understanding medical care of transplant recipients through integrated registry and pharmacy claims data
    Krista L Lentine
    Center for Outcomes Research, Saint Louis University School of Medicine, St Louis, MO, USA
    Am J Nephrol 38:420-9. 2013
    ..Limited data exist on medication use aside from immunosuppression among large samples of kidney transplant recipients...
  55. ncbi request reprint CMV infection of the renal allograft is much more common than the pathology indicates: a retrospective analysis of qualitative and quantitative buffy coat CMV-PCR, renal biopsy pathology and tissue CMV-PCR
    Helen Liapis
    Department of Pathology and Immunology, School of Medicine, Washington University, 660 South Euclid Avenue, Campus Box 8118, St Louis, MO 63110 1093, USA
    Nephrol Dial Transplant 18:397-402. 2003
    ..The relationship between quantitative blood CMV and renal allograft pathology is unknown...
  56. pmc Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing
    Efrem S Lim
    Departments of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Virology 436:295-303. 2013
    ..The discovery of STLPyV highlights a novel alternative splicing strategy and advances our understanding of the complex evolutionary history of polyomaviruses...
  57. ncbi request reprint Is there a correlation between atherosclerosis and renal resistive indices in kidney transplant recipients?
    Daniel C Brennan
    Washington University School of Medicine, St Louis, MO, USA
    Nat Clin Pract Nephrol 2:64-5. 2006
  58. ncbi request reprint Faith supported by reason: mechanistic support for the use of polyclonal antibodies in transplantation
    Daniel C Brennan
    Barnes Jewish Hospital, Washington University, St Louis, MO, USA
    Transplantation 75:577-8. 2003
  59. ncbi request reprint Anemia in the kidney-transplant patient
    Heidi Joist
    Renal Division, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Adv Chronic Kidney Dis 13:4-10. 2006
    ....
  60. doi request reprint Effect of maintenance immunosuppressive drugs on virus pathobiology: evidence and potential mechanisms
    Daniel C Brennan
    Washington University in St Louis, St Louis, MO 63110, USA
    Rev Med Virol 23:97-125. 2013
    ....
  61. pmc Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome
    Imran A Memon
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA
    J Transplant 2012:761283. 2012
    ..None were deemed significant. No patient developed clinically evident BKVAN. Our data support, at a genomic level, the effectiveness of reduction of immunosuppression for prevention of progression from viremia to BKVAN...
  62. ncbi request reprint Statin use after renal transplantation: a systematic quality review of trial-based evidence
    Krista L Lentine
    Division of Nephrology, Washington University Medical Center, Campus Box 8219, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Nephrol Dial Transplant 19:2378-86. 2004
    ..We assessed whether current clinical evidence supports the use of statins to improve cardiac and/or renal outcomes after kidney transplantation...
  63. pmc EBV-associated recurrent Hodgkin's disease after renal transplantation
    Katherine H Flanagan
    Washington University School of Medicine, Department of Internal Medicine, Renal Division, St Louis, MO 63110, USA
    Transpl Int 19:338-41. 2006
    ....