Research Topics
| TODD BRAVERSummaryAffiliation: Washington University School of Medicine Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
The variable nature of cognitive control: a dual mechanisms frameworkTodd S Braver
Department of Psychology, Washington University in St Louis, St Louis, MO 63130, USA
Trends Cogn Sci 16:106-13. 2012....
Direct comparison of prefrontal cortex regions engaged by working and long-term memory tasksT S Braver
Department of Psychology, Washington University, St Louis, Missouri 63130, USA
Neuroimage 14:48-59. 2001..g., task-selectivity vs material-selectivity in DL-PFC and VL-PFC) and for testing the applicability of memory domain-specific theories (e.g., FP-PFC in LTM retrieval)...
Extracting core components of cognitive controlTodd S Braver
Department of Psychology, Washington University, St Louis, MO 63130, USA
Trends Cogn Sci 10:529-32. 2006..A recent neuroimaging study by Dosenbach et al. offers a set of novel methodological tools to examine this issue and uncovers new candidate brain regions for a core system that might implement task sets...
Flexible neural mechanisms of cognitive control within human prefrontal cortexTodd S Braver
Department of Psychology, Washington University, St Louis, MO 63130, USA
Proc Natl Acad Sci U S A 106:7351-6. 2009....
Context processing and context maintenance in healthy aging and early stage dementia of the Alzheimer's typeTodd S Braver
Department of Psychology, Washington University, St Louis, MO 63130, USA
Psychol Aging 20:33-46. 2005..The results suggest that context processing may be composed of functionally dissociable components and point to the utility of this construct in understanding the timecourse of cognitive decline in healthy and pathological aging...
A theory of cognitive control, aging cognition, and neuromodulationTodd S Braver
Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
Neurosci Biobehav Rev 26:809-17. 2002..These findings highlight the utility of a computational approach to cognitive aging. Current directions for further refinement and validation of the model are outlined...
Neural mechanisms of transient and sustained cognitive control during task switchingTodd S Braver
Department of Psychology, Washington University, St Louis, MO 63130, USA
Neuron 39:713-26. 2003....
Vive les differences! Individual variation in neural mechanisms of executive controlTodd S Braver
Department of Psychology, Washington University in St Louis, St Louis, MO, USA
Curr Opin Neurobiol 20:242-50. 2010....
Anterior cingulate cortex and response conflict: effects of frequency, inhibition and errorsT S Braver
Department of Psychology, Washington University, St Louis, MO 63130, USA
Cereb Cortex 11:825-36. 2001....
Context processing in older adults: evidence for a theory relating cognitive control to neurobiology in healthy agingT S Braver
Department of Psychology, Washington University, St Louis, Missouri 63130, USA
J Exp Psychol Gen 130:746-63. 2001..Older adults exhibited both performance decrements and, counterintuitively, performance improvements that are in close agreement with model predictions...
The role of frontopolar cortex in subgoal processing during working memoryTodd S Braver
Department of Psychology, Washington University, St Louis, MO 63130, USA
Neuroimage 15:523-36. 2002..These results suggest a triple dissociation of function within PFC regions, and further indicate that FP-PFC is selectively engaged by the requirement to monitor and integrate subgoals during WM tasks...
Intellect as distinct from Openness: differences revealed by fMRI of working memoryColin G DeYoung
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
J Pers Soc Psychol 97:883-92. 2009..Intellect was also correlated significantly with scores on tests of intelligence and WM capacity, but the association of Intellect with brain activity could not be entirely explained by cognitive ability...
Primary and secondary rewards differentially modulate neural activity dynamics during working memoryStefanie M Beck
Department of Psychology, Washington University in St Louis, St Louis, Missouri, United States of America
PLoS ONE 5:e9251. 2010..Cognitive control and working memory processes have been found to be influenced by changes in motivational state. Nevertheless, the impact of different motivational variables on behavior and brain activity remains unclear...
Individual differences in delay discounting: relation to intelligence, working memory, and anterior prefrontal cortexNoah A Shamosh
Department of Psychology, Yale University, New Haven, CT, USA
Psychol Sci 19:904-11. 2008..Overall, the results suggest that delay discounting is associated with intelligence in part because of processes instantiated in anterior prefrontal cortex, a region known to support the integration of diverse information...
Neural mechanisms of general fluid intelligenceJeremy R Gray
Department of Psychology, Washington University, Campus Box 1125, St. Louis, Missouri 63130, USA
Nat Neurosci 6:316-22. 2003....
Strategy-dependent changes in memory: effects on behavior and brain activityNicole K Speer
Washington University, St. Louis, Missouri 63130, USA
Cogn Affect Behav Neurosci 3:155-67. 2003..Taken together, the results imply that covert cognitive strategies play an important role in modulating brain activation and behavior during memory tasks...
Sustained neural activity associated with cognitive control during temporally extended decision makingTal Yarkoni
Department of Psychology, Washington University, Campus Box 1125, St. Louis, MO 63130, USA
Brain Res Cogn Brain Res 23:71-84. 2005..These results demonstrate the contribution of cognitive control mechanisms to temporally extended decision-making paradigms and highlight the benefits of decomposing activation responses into sustained and transient components...
Integration of emotion and cognition in the lateral prefrontal cortexJeremy R Gray
Department of Psychology, Washington University, One Brookings Drive, St. Louis, MO 63130, USA
Proc Natl Acad Sci U S A 99:4115-20. 2002..Other regions in lateral PFC showed hemispheric specialization for emotion and for stimuli separately, consistent with a hierarchical and hemisphere-based mechanism of integration...
Cognitive control, goal maintenance, and prefrontal function in healthy agingJessica L Paxton
Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, Washington University, St Louis, MO 63139, USA
Cereb Cortex 18:1010-28. 2008..These results are consistent with the hypothesis that age-related impairments in goal maintenance abilities cause a compensatory shift in older adults from a proactive (seen in young adults) to a reactive cognitive control strategy...
Prefrontal cortex and dynamic categorization tasks: representational organization and neuromodulatory controlRandall C O'Reilly
Department of Psychology, University of Colorado, Boulder, CO 80309, USA
Cereb Cortex 12:246-57. 2002..with orbital versus dorsolateral lesions supports the validity of these principles, many of which have also been useful in accounting for other frontal phenomena...
Personality predicts working-memory-related activation in the caudal anterior cingulate cortexJeremy R Gray
Department of Psychology, Washington University, St Louis, Missouri 63130, USA
Cogn Affect Behav Neurosci 2:64-75. 2002..84), suggesting personality differences in cognitive control. The data bolster approach-withdrawal (action control) theories of personality and suggest refinements to the dominant views of ACC and personality...
Age-related changes in neural activity during performance matched working memory manipulationLisa Emery
Department of Psychology, Washington University, Saint Louis, MO 63139, USA
Neuroimage 42:1577-86. 2008..The results suggest that activation and age-differences in lateral PFC engagement during WM manipulation conditions may reflect strategy use and controlled processing demands rather than reflect the act of manipulation per se...
Distinct neural circuits support transient and sustained processes in prospective memory and working memoryJeremy R Reynolds
Department of Psychology, University of Colorado, Boulder, CO 80302, USA
Cereb Cortex 19:1208-21. 2009..The results support the conclusion that both sustained and transient processes contribute to efficient PM and provide novel constraints on the functional role of anterior PFC in higher-order cognition...
Opiate addicts lack error-dependent activation of rostral anterior cingulateSteven D Forman
Department of Psychology (TSB, DMB, Washington University, St. Louis, Missouri, USA
Biol Psychiatry 55:531-7. 2004..CONCLUSIONS: The attenuation of this error signal in anterior cingulate cortex may play a role in loss of control in addiction and other forms of impulsive behavior...
The effect of age on rule-based category learningCaroline A Racine
Washington University, Department of Psychology, St Louis, Missouri, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:411-34. 2006..These results are discussed in reference to the growing body of literature regarding age-related change in executive abilities and frontal lobe function...
A computational model of anterior cingulate function in speeded response tasks: effects of frequency, sequence, and conflictAndrew D Jones
Washington University, St. Louis, Missouri 63130, USA
Cogn Affect Behav Neurosci 2:300-17. 2002..The results indicate that the conflict-monitoring hypothesis, augmented by mechanisms for encoding stimulus history, can explain key phenomena associated with performance in sequential speeded response tasks...
Learned predictions of error likelihood in the anterior cingulate cortexJoshua W Brown
Department of Psychology, CB 1125, Washington University, St Louis, MO 63130, USA
Science 307:1118-21. 2005..These results support a more general error-likelihood theory of ACC function based on reinforcement learning, of which conflict and error detection are special cases...
Are people really more patient than other animals? Evidence from human discounting of real liquid rewardsKoji Jimura
Department of Psychology, Washington University, Campus, One Brookings Drive, St Louis, MO 63130, USA
Psychon Bull Rev 16:1071-5. 2009....
Motivational influences on cognitive control: behavior, brain activation, and individual differencesHannah S Locke
Department of Psychology, Washington University, St Louis, Missouri 63130, USA
Cogn Affect Behav Neurosci 8:99-112. 2008..These results suggest that changes in motivational state may modulate performance through sustained activity in cognitive control regions and that the effect of incentives may be affected by the personalities of the participants...
Principles of pleasure prediction: specifying the neural dynamics of human reward learningTodd S Braver
Department of Psychology, Washington University, St. Louis, MO 63139, USA
Neuron 38:150-2. 2003..and O'Doherty et al. use event-related fMRI to provide some of the strongest evidence to date that the reward prediction error model of dopamine system activity applies equally well to human reward learning...
CNTRICS final task selection: executive controlDeanna M Barch
Department of Psychology, Washington University, St Louis, MO 63130, USA
Schizophr Bull 35:115-35. 2009..This article describes the ways in which each of these tasks met the criteria used by the breakout group to recommend tasks for further development...
BOLD correlates of trial-by-trial reaction time variability in gray and white matter: a multi-study fMRI analysisTal Yarkoni
Department of Psychology, Washington University, Saint Louis, Missouri, United States of America
PLoS ONE 4:e4257. 2009..Using a multi-study approach, we investigated whether there are brain regions that show a general relationship between trial-by-trial RT variability and activation across a range of cognitive tasks...
Context-processing deficits in schizophrenia: diagnostic specificity, 4-week course, and relationships to clinical symptomsDeanna M Barch
Department of Psychology, St Louis, Missouri 63130 4899, USA
J Abnorm Psychol 112:132-43. 2003..However, context-processing deficits improved in the psychotic comparison group at 4 weeks but did not improve in patients with schizophrenia...
Age-related shifts in brain activity dynamics during task switchingKoji Jimura
Department of Psychology, Washington University in St Louis, St Louis, MO 63139, USA
Cereb Cortex 20:1420-31. 2010..Together, these results suggest that older adults may shift from a proactive to reactive cognitive control strategy as a means of retaining relatively preserved behavioral performance in the face of age-related neurocognitive changes...
Prefrontal cortex mediation of cognitive enhancement in rewarding motivational contextsKoji Jimura
Department of Psychology, Washington University, St Louis, MO 63130, USA
Proc Natl Acad Sci U S A 107:8871-6. 2010..Reward-sensitive individuals appear preferentially motivated to adopt this resource-demanding strategy, resulting in paradoxical benefits selectively for nonrewarded events...
Motivated cognitive control: reward incentives modulate preparatory neural activity during task-switchingAdam C Savine
Department of Psychology, Washington University, St Louis, Missouri 63139, USA
J Neurosci 30:10294-305. 2010....
Exploring emotional and cognitive conflict using speeded voluntary facial expressionsKimberly S Chiew
Department of Psychology, Washington University, St Louis, MO 63130, USA
Emotion 10:842-54. 2010....
Item- and task-level processes in the left inferior prefrontal cortex: positive and negative correlates of encodingJeremy R Reynolds
Department of Psychology, Washington University, Saint Louis, MO 63139, USA
Neuroimage 21:1472-83. 2004..When devoted to the latter, the diversion of LIPC processes to the task level can have a negative consequence for item-level analysis and encoding...
Dopaminergic modulation of response inhibition: an fMRI studyTamara Hershey
Psychiatry Department, Washington University School of Medicine, USA
Brain Res Cogn Brain Res 20:438-48. 2004..In summary, right parietal and cerebellar regions important in mediating specific aspects of the GNG task were modulated by levodopa, suggesting a region-specific role for dopamine in response inhibition...
Functional specializations in lateral prefrontal cortex associated with the integration and segregation of information in working memoryNicola De Pisapia
Department of Psychology, Washington University, Saint Louis, MO 63139, USA
Cereb Cortex 17:993-1006. 2007....
Effects of environmental support and strategy training on older adults' use of contextJessica L Paxton
Department of Psychology, Washington University, St Louis, MO 63139, USA
Psychol Aging 21:499-509. 2006..These results suggest that age-related differences in context processing can be ameliorated by directed strategy training or extended practice...
Prefrontal brain activity predicts temporally extended decision-making behaviorTal Yarkoni
Washington University, Department of Psychology, St Louis, Missouri 63130, USA
J Exp Anal Behav 84:537-54. 2005....
A direct comparison of anterior prefrontal cortex involvement in episodic retrieval and integrationJeremy R Reynolds
Department of Psychology, Washington University, Saint Louis, MO 63139, USA
Cereb Cortex 16:519-28. 2006..Moreover, the study highlights the benefits of activation latency analysis for understanding functional contributions and dissociations between closely linked brain regions...
Event perception: a mind-brain perspectiveJeffrey M Zacks
Department of Psychology, Washington University, St Louis, MO 63130, USA
Psychol Bull 133:273-93. 2007....
Neural circuitry of emotional and cognitive conflict revealed through facial expressionsKimberly S Chiew
Department of Psychology, Washington University in St Louis, St Louis, Missouri, United States of America
PLoS ONE 6:e17635. 2011....
Prefrontal cortex and flexible cognitive control: rules without symbolsNicolas P Rougier
Department of Psychology, University of Colorado, 345 UCB, Boulder, CO 80309, USA
Proc Natl Acad Sci U S A 102:7338-43. 2005..The same model is shown to apply to benchmark PFC tasks (Stroop and Wisconsin card sorting), accurately simulating the behavior of neurologically intact and frontally damaged people...
Cognitive-pharmacologic functional magnetic resonance imaging in tourette syndrome: a pilot studyTamara Hershey
Department of Psychiatry, Washington University, St. Louis, Missouri, USA
Biol Psychiatry 55:916-25. 2004..05). CONCLUSIONS: These results are consistent with a dopamine-influenced functional abnormality of brain response in TS and suggest testable hypotheses about the mechanism by which dopamine antagonists and agonists alleviate tics...
Computational perspectives on dopamine function in prefrontal cortexJonathan D Cohen
Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
Curr Opin Neurobiol 12:223-9. 2002..Recently, computational models have tried to elucidate the specific and intricate roles of dopamine in the prefrontal cortex, at the neurophysiological, system and behavioral levels, with varying degrees of success...
Reliability of functional localization using fMRIKhena M Swallow
Washington University, St. Louis, MO 63130-1125, USA
Neuroimage 20:1561-77. 2003..We conclude that, for typical sample sizes and numbers of observations per subject, functional localization is most reliable when performed for each individual using data in atlas space...
A computational model of fractionated conflict-control mechanisms in task-switchingJoshua W Brown
Department of Psychology, Washington University, St Louis, MO 63130, USA
Cogn Psychol 55:37-85. 2007..The results suggest numerous testable predictions regarding the neural substrates of cognitive control...
Mechanisms underlying dependencies of performance on stimulus history in a two-alternative forced-choice taskRaymond Y Cho
Princeton University, Princeton, New Jersey, USA
Cogn Affect Behav Neurosci 2:283-99. 2002....
Affective personality differences in neural processing efficiency confirmed using fMRIJeremy R Gray
Psychology Department, Yale University, Box 208205, New Haven, CT 06520, USA
Cogn Affect Behav Neurosci 5:182-90. 2005....
A computational model of risk, conflict, and individual difference effects in the anterior cingulate cortexJoshua W Brown
Department of Psychological and Brain Sciences, Indiana University, 1101 E Tenth St, Bloomington, IN 47405, USA
Brain Res 1202:99-108. 2008..The results clarify the basic computational mechanisms of learned risk aversion and may have broad implications for predicting and managing risky behavior in healthy and clinical populations...
Accounting for cognitive aging: context processing, inhibition or processing speed?Beth K Rush
Mayo Clinic College of Medicine, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:588-610. 2006..The sensitivity of the AX-CPT to cognitive aging is discussed in the context of existing theories of cognitive aging. The authors suggest that deficits in context processing and utilization may underlie cognitive aging phenomena...
Individual differences in amygdala activity predict response speed during working memoryAlexandre Schaefer
Psychology Department, Yale University, New Haven, Connecticut 06520, USA
J Neurosci 26:10120-8. 2006..These results support models of amygdala function that can account for its involvement not only in emotion but also higher cognition...
Executive functioning component mechanisms and schizophreniaJohn G Kerns
Department of Psychological Sciences, University of Missouri, Columbia, Missouri 65211, USA
Biol Psychiatry 64:26-33. 2008..Although there is general consensus about what cognitive tasks involve executive functioning, there is disagreement about the specific cognitive mechanisms that comprise executive functioning...
Risk prediction and aversion by anterior cingulate cortexJoshua W Brown
Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana 47405, USA
Cogn Affect Behav Neurosci 7:266-77. 2007..Taken together, the results are consistent with an expected risk model of ACC and suggest that ACC may generally contribute to cognitive control by recruiting brain activity to avoid risk...
Preparation for integration: the role of anterior prefrontal cortex in working memoryNicola De Pisapia
CIMeC Center for Mind Brain Sciences, University of Trento, Mattarello TN, Italy
Neuroreport 19:15-9. 2008..We find that this region is involved in the preparation for integration, possibly by ensuring that goal-relevant information is maintained in an accessible form, while at the same time protected from subtask interference...
Individual differencesSharon L Thompson-Schill
Cogn Affect Behav Neurosci 5:115-6. 2005
Medial frontal cortex function: an introduction and overviewK Richard Ridderinkhof
University of Amsterdam, Amsterdam, The Netherlands
Cogn Affect Behav Neurosci 7:261-5. 2007..The present article presents a brief introduction, overview, and road map to the field and to the special issue devoted to MFC function...
Research Grants
- Dual Mechanisms of Cognitive ControlTodd S Braver; Fiscal Year: 2010..Such knowledge could be used to drive the development of more effective interventions ..
- Dual Mechanisms of Cognitive ControlTODD BRAVER; Fiscal Year: 2009..Such knowledge could be used to drive the development of more effective interventions ..
- Dual Mechanisms of Cognitive ControlTODD BRAVER; Fiscal Year: 2009..Such knowledge could be used to drive the development of more effective interventions ..
- NEUROECONOMICS OF AGE RELATED CHANGES IN COGNITIVE CONTROLTODD BRAVER; Fiscal Year: 2007....
- Dual Mechanisms of Cognitive ControlTODD BRAVER; Fiscal Year: 2006..Such knowledge could be used to drive the development of more effective interventions. ..
- Dual Mechanisms of Cognitive ControlTodd S Braver; Fiscal Year: 2011..Such knowledge could be used to drive the development of more effective interventions ..
