Jeffrey Bradley

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Comparison of helical, maximum intensity projection (MIP), and averaged intensity (AI) 4D CT imaging for stereotactic body radiation therapy (SBRT) planning in lung cancer
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Radiother Oncol 81:264-8. 2006
  2. pmc A nomogram to predict radiation pneumonitis, derived from a combined analysis of RTOG 9311 and institutional data
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 69:985-92. 2007
  3. pmc Primary analysis of the phase II component of a phase I/II dose intensification study using three-dimensional conformal radiation therapy and concurrent chemotherapy for patients with inoperable non-small-cell lung cancer: RTOG 0117
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, Alvin J Siteman Comprehensive Cancer Center, 4921 Parkview Place, St Louis, MO, USA
    J Clin Oncol 28:2475-80. 2010
  4. doi request reprint Stereotactic body radiation therapy for early-stage non-small-cell lung cancer: the pattern of failure is distant
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 77:1146-50. 2010
  5. pmc A phase I/II radiation dose escalation study with concurrent chemotherapy for patients with inoperable stages I to III non-small-cell lung cancer: phase I results of RTOG 0117
    Jeffrey D Bradley
    Washington University School of Medicine, St Louis, Missouri, USA
    Int J Radiat Oncol Biol Phys 77:367-72. 2010
  6. ncbi request reprint Radiographic response and clinical toxicity following SBRT for stage I lung cancer
    Jeffrey Bradley
    Department of Radiation Oncology, Washington University School of Medicine, Alvin J Siteman Cancer Center, St Louis, Missouri, USA
    J Thorac Oncol 2:S118-24. 2007
  7. ncbi request reprint Reduction of motion blurring artifacts using respiratory gated CT in sinogram space: a quantitative evaluation
    Wei Lu
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 32:3295-304. 2005
  8. ncbi request reprint Radiation-induced myonecrosis presenting as a subcutaneous mass after combined modality therapy for non-small cell lung cancer
    Vamsidhar Velcheti
    Division of Oncology, Alvin J Siteman Cancer Center Washington University School of Medicine, St Louis, Missouri, USA
    J Thorac Oncol 2:875-6. 2007
  9. ncbi request reprint Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors
    Issam El Naqa
    Department of Radiation Oncology, Washington University, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 64:1275-86. 2006
  10. ncbi request reprint Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer
    Jeffrey Bradley
    Department of Radiation Oncology, Mallinkrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 59:78-86. 2004

Collaborators

Detail Information

Publications66

  1. ncbi request reprint Comparison of helical, maximum intensity projection (MIP), and averaged intensity (AI) 4D CT imaging for stereotactic body radiation therapy (SBRT) planning in lung cancer
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Radiother Oncol 81:264-8. 2006
    ....
  2. pmc A nomogram to predict radiation pneumonitis, derived from a combined analysis of RTOG 9311 and institutional data
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 69:985-92. 2007
    ....
  3. pmc Primary analysis of the phase II component of a phase I/II dose intensification study using three-dimensional conformal radiation therapy and concurrent chemotherapy for patients with inoperable non-small-cell lung cancer: RTOG 0117
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, Alvin J Siteman Comprehensive Cancer Center, 4921 Parkview Place, St Louis, MO, USA
    J Clin Oncol 28:2475-80. 2010
    ..The radiation dose was 74 Gy given in 37 fractions. Radiation therapy volumes included those of the gross tumor and involved nodes. The volume of lung at or exceeding 20 Gy (V20) was mandated to be <or= 30%...
  4. doi request reprint Stereotactic body radiation therapy for early-stage non-small-cell lung cancer: the pattern of failure is distant
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 77:1146-50. 2010
    ..We reviewed our experience using either three- or five-fraction SBRT for peripheral or central tumors, respectively...
  5. pmc A phase I/II radiation dose escalation study with concurrent chemotherapy for patients with inoperable stages I to III non-small-cell lung cancer: phase I results of RTOG 0117
    Jeffrey D Bradley
    Washington University School of Medicine, St Louis, Missouri, USA
    Int J Radiat Oncol Biol Phys 77:367-72. 2010
    ....
  6. ncbi request reprint Radiographic response and clinical toxicity following SBRT for stage I lung cancer
    Jeffrey Bradley
    Department of Radiation Oncology, Washington University School of Medicine, Alvin J Siteman Cancer Center, St Louis, Missouri, USA
    J Thorac Oncol 2:S118-24. 2007
    ..The reported toxicities following SBRT for both peripheral and central lung cancers are also reviewed...
  7. ncbi request reprint Reduction of motion blurring artifacts using respiratory gated CT in sinogram space: a quantitative evaluation
    Wei Lu
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 32:3295-304. 2005
    ..Image artifacts were evaluated in the diaphragm, where high contrast interfaces intercepted the imaging plane. For patients, this respiratory gating technique reduced the blurring artifacts by 9%-41% at the lung-diaphragm interface...
  8. ncbi request reprint Radiation-induced myonecrosis presenting as a subcutaneous mass after combined modality therapy for non-small cell lung cancer
    Vamsidhar Velcheti
    Division of Oncology, Alvin J Siteman Cancer Center Washington University School of Medicine, St Louis, Missouri, USA
    J Thorac Oncol 2:875-6. 2007
  9. ncbi request reprint Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors
    Issam El Naqa
    Department of Radiation Oncology, Washington University, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 64:1275-86. 2006
    ..Current models are usually oversimplified. We describe alternative methods for building multivariable dose-response models...
  10. ncbi request reprint Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer
    Jeffrey Bradley
    Department of Radiation Oncology, Mallinkrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 59:78-86. 2004
    ....
  11. ncbi request reprint Increasing tumor volume is predictive of poor overall and progression-free survival: secondary analysis of the Radiation Therapy Oncology Group 93-11 phase I-II radiation dose-escalation study in patients with inoperable non-small-cell lung cancer
    Maria Werner-Wasik
    Department of Radiation Oncology, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 70:385-90. 2008
    ..9, 77.4, 83.8, or 90.3 Gy. The locoregional control and survival rates were similar among the various dose levels. We investigated the effect of the gross tumor volume (GTV) on the outcome...
  12. ncbi request reprint Toxicity and outcome results of RTOG 9311: a phase I-II dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma
    Jeffrey Bradley
    Department of Radiation Oncology, Washington University Siteman Cancer Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 61:318-28. 2005
    ..To evaluate prospectively the acute and late morbidities from a multiinstitutional three-dimensional radiotherapy dose-escalation study for inoperable non-small-cell lung cancer...
  13. ncbi request reprint Analysis of first recurrence and survival in patients with stage I non-small cell lung cancer treated with surgical resection or stereotactic radiation therapy
    Traves D Crabtree
    Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo Electronic address
    J Thorac Cardiovasc Surg 147:1183-1191; discussion 1191-2. 2014
    ..Comparative studies of survival between stereotactic body radiation therapy (SBRT) and surgery have been limited by lack of comparisons of recurrence patterns between matched cohorts in non-small cell lung cancer (NSCLC)...
  14. ncbi request reprint Recent advances and future perspectives in the management of lung cancer
    Alexander Sasha Krupnick
    Washington University School of Medicine, St Louis, MO, USA
    Curr Probl Surg 42:540-610. 2005
  15. ncbi request reprint 18F-FDG PET definition of gross tumor volume for radiotherapy of non-small cell lung cancer: is a single standardized uptake value threshold approach appropriate?
    Kenneth J Biehl
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri, USA
    J Nucl Med 47:1808-12. 2006
    ....
  16. ncbi request reprint Quantitation of the reconstruction quality of a four-dimensional computed tomography process for lung cancer patients
    Wei Lu
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 32:890-901. 2005
    ..The 4D reconstruction provides the CT data required to measure the three-dimensional trajectory of tumor and lung tissue during free breathing...
  17. ncbi request reprint Treatment of stage I lung cancer in high-risk and inoperable patients: comparison of prospective clinical trials using stereotactic body radiotherapy (RTOG 0236), sublobar resection (ACOSOG Z4032), and radiofrequency ablation (ACOSOG Z4033)
    Traves Crabtree
    Division of Thoracic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Thorac Cardiovasc Surg 145:692-9. 2013
    ....
  18. pmc A phase II comparative study of gross tumor volume definition with or without PET/CT fusion in dosimetric planning for non-small-cell lung cancer (NSCLC): primary analysis of Radiation Therapy Oncology Group (RTOG) 0515
    Jeffrey Bradley
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 82:435-41.e1. 2012
    ....
  19. doi request reprint A clinical model to estimate recurrence risk in resected stage I non-small cell lung cancer
    Boone Goodgame
    Division of Medical Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Clin Oncol 31:22-8. 2008
    ..There are no reliable markers to predict recurrence in resected Stage I non-small cell lung cancer (NSCLC). A validated clinical model to estimate the risk of recurrence would help select patients for adjuvant therapy...
  20. ncbi request reprint Retrospective monte carlo dose calculations with limited beam weight information
    Patricia E Lindsay
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 34:334-46. 2007
    ..The method provides heterogeneity-corrected dose data consistent with convolution-superposition calculations and is one feasible approach for improving dosimetric data for outcomes analyses...
  21. ncbi request reprint Predictors of radiation-induced esophageal toxicity in patients with non-small-cell lung cancer treated with three-dimensional conformal radiotherapy
    Anurag K Singh
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 55:337-41. 2003
    ....
  22. pmc Effect of novel amplitude/phase binning algorithm on commercial four-dimensional computed tomography quality
    Jeffrey R Olsen
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 70:243-52. 2008
    ..The aim of this study was to examine the effect of respiratory irregularities on four-dimensional computed tomography, and to evaluate a novel image reconstruction algorithm using percentile-based tagging of the respiratory cycle...
  23. ncbi request reprint A comparison between amplitude sorting and phase-angle sorting using external respiratory measurement for 4D CT
    Wei Lu
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 33:2964-74. 2006
    ..Overall, amplitude sorting performed better than phase angle sorting for 33 of the 35 patients and equally well for two patients who were immobilized with a stereotactic body frame and an abdominal compression plate...
  24. doi request reprint The validation of tomotherapy dose calculations in low-density lung media
    Summer R Chaudhari
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Phys Med Biol 54:2315-22. 2009
    ..The phantom developed for this work enabled detailed quality-assurance testing under realistic conditions with heterogeneous media...
  25. pmc Distribution of lung tissue hysteresis during free breathing
    Benjamin White
    Department of Radiation Oncology, University of California Los Angeles, Westwood, 200 Medical Plaza, Suite B265, Los Angeles, California 90095, USA
    Med Phys 40:043501. 2013
    ..To characterize and quantify free breathing lung tissue motion distributions...
  26. pmc Stereotactic body radiation therapy for inoperable early stage lung cancer
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    JAMA 303:1070-6. 2010
    ..Patients with early stage but medically inoperable lung cancer have a poor rate of primary tumor control (30%-40%) and a high rate of mortality (3-year survival, 20%-35%) with current management...
  27. ncbi request reprint Dosimetric correlates for acute esophagitis in patients treated with radiotherapy for lung carcinoma
    Jeffrey Bradley
    Department of Radiation Oncology, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 58:1106-13. 2004
    ..Therefore, our aim was to determine whether the irradiated esophageal surface area and/or esophageal volume are predictive of acute esophagitis in relation to other clinical and treatment-related factors...
  28. ncbi request reprint Molecular (functional) imaging for radiotherapy applications: an RTOG symposium
    J D Chapman
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 55:294-301. 2003
  29. pmc Assessment of intrafraction mediastinal and hilar lymph node movement and comparison to lung tumor motion using four-dimensional CT
    Eric D Donnelly
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 69:580-8. 2007
    ..To quantify the amount of free-breathing motion measured using Four-dimensional (4D) CT scans of mediastinal and hilar lymph nodes and to compare this motion to the primary lung tumor motion...
  30. ncbi request reprint Localization of internal mammary lymph nodes by CT simulation: implications for breast radiation therapy planning
    David B Mansur
    Department of Radiation Oncology and Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4921 Parkview Place, Box 8224, St Louis, MO 63110, USA
    Radiother Oncol 73:355-7. 2004
    ..In an attempt to simplify their localization for treatment planning purposes, the position of the internal mammary lymph nodes was systematically studied in 65 breast cancer patients undergoing CT simulation...
  31. ncbi request reprint Modeling radiation pneumonitis risk with clinical, dosimetric, and spatial parameters
    Andrew J Hope
    Department of Radiation Oncology, Washington University School of Medicine, Siteman Cancer Center, St Louis, Missouri 63110 1032, USA
    Int J Radiat Oncol Biol Phys 65:112-24. 2006
    ..To determine the clinical, dosimetric, and spatial parameters that correlate with radiation pneumonitis...
  32. pmc A phase I study of temsirolimus and thoracic radiation in non-small-cell lung cancer
    Saiama N Waqar
    Division of Medical Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO
    Clin Lung Cancer 15:119-23. 2014
    ..Inhibition of the mTOR pathway has been found to augment the cytotoxic effect of radiation in preclinical studies. There is scant clinical experience with mTOR inhibitors and radiation...
  33. ncbi request reprint A review of radiation dose escalation trials for non-small cell lung cancer within the Radiation Therapy Oncology Group
    Jeffrey Bradley
    Department of Radiation Oncology, A J Siteman Comprehensive Cancer Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Semin Oncol 32:S111-3. 2005
    ..When concurrent chemotherapy and 3-dimensional conformal RT are used, the maximum tolerated dose of radiation is reduced, and current indications suggest that the maximum tolerated dose in this setting is in the range of 70 to 74 Gy...
  34. doi request reprint Fiducial-based translational localization accuracy of electromagnetic tracking system and on-board kilovoltage imaging system
    Lakshmi Santanam
    Division of Medical Physics, Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Int J Radiat Oncol Biol Phys 70:892-9. 2008
    ..This investigation compared the static and dynamic tracking accuracy of this system to that of an on-board imaging kilovoltage X-ray system for concurrent use of the two systems...
  35. ncbi request reprint Radiation pneumonitis and esophagitis in thoracic irradiation
    Jeffrey Bradley
    Department of Radiation Oncology, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA
    Cancer Treat Res 128:43-64. 2006
  36. ncbi request reprint Functional imaging in treatment planning in radiation therapy: a review
    Carlos A Perez
    Department of Radiation Oncology, Washington University Medical Center, St Louis, MO, USA
    Rays 27:157-73. 2002
    ..The recent introduction of a combined CT and PET scanner will substantially simplify image acquisition and treatment planning...
  37. ncbi request reprint In vivo assessment of tumor hypoxia in lung cancer with 60Cu-ATSM
    Farrokh Dehdashti
    Division of Nuclear Medicine, Edward Mallinckrodt Institute of Radiology, St Louis, MO 63110, USA
    Eur J Nucl Med Mol Imaging 30:844-50. 2003
    ..04; P=0.9). (60)Cu-ATSM-PET can be readily performed in patients with NSCLC and the tumor uptake of (60)Cu-ATSM reveals clinically unique information about tumor oxygenation that is predictive of tumor response to therapy...
  38. ncbi request reprint Radiation esophagitis: Predictive factors and preventive strategies
    Jeffrey Bradley
    Department of Radiation Oncology, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Semin Radiat Oncol 14:280-6. 2004
    ..Preventive strategies to minimize this toxicity also are explored. Overall, this article reviews the current understanding of radiation toxicity for the esophagus...
  39. doi request reprint Datamining approaches for modeling tumor control probability
    Issam El Naqa
    Department of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Acta Oncol 49:1363-73. 2010
    ....
  40. pmc Application of the continuity equation to a breathing motion model
    Daniel A Low
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 37:1360-4. 2010
    ..To quantitatively test a breathing motion model using the continuity equation and clinical data...
  41. doi request reprint Stereotactic body radiation therapy versus surgical resection for stage I non-small cell lung cancer
    Traves D Crabtree
    Department of Thoracic Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Thorac Cardiovasc Surg 140:377-86. 2010
    ..This study compares short-term outcomes between stereotactic body radiation therapy and surgical treatment of non-small cell lung cancer...
  42. doi request reprint The treatment of early-stage disease
    Clifford G Robinson
    Department of Radiation Oncology, Washington University School of Medicine St Louis, MO, USA
    Semin Radiat Oncol 20:178-85. 2010
    ..In this review we address each of these points, with particular emphasis on recent or ongoing prospective trials...
  43. pmc Bioinformatics methods for learning radiation-induced lung inflammation from heterogeneous retrospective and prospective data
    Sarah J Spencer
    Department of Radiation Oncology, Washington University Medical School, Saint Louis, MO 63110, USA
    J Biomed Biotechnol 2009:892863. 2009
    ..Our proteomics strategy yielded promising protein candidates, but their role in RP as well as their interactions with dose-volume metrics remain to be determined...
  44. pmc Radiation dose-volume effects in the lung
    Lawrence B Marks
    Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC 27514, USA
    Int J Radiat Oncol Biol Phys 76:S70-6. 2010
    ..The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects...
  45. pmc Characterization of free breathing patterns with 5D lung motion model
    Tianyu Zhao
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 36:5183-9. 2009
    ..To determine the quiet respiration breathing motion model parameters for lung cancer and nonlung cancer patients...
  46. ncbi request reprint A phase III comparison of radiation therapy with or without recombinant beta-interferon for poor-risk patients with locally advanced non-small-cell lung cancer (RTOG 93-04)
    Jeffrey D Bradley
    Radiation Oncology Center, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 52:1173-9. 2002
    ..Based on these data, the Radiation Therapy Oncology Group (RTOG) initiated a Phase III trial to test the efficacy of beta-interferon in poor-risk patients with Stages IIIA and IIIB non-small-cell lung carcinoma...
  47. ncbi request reprint The impact of central lung distance, maximal heart distance, and radiation technique on the volumetric dose of the lung and heart for intact breast radiation
    Feng Ming Kong
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 54:963-71. 2002
    ..To investigate the impact of radiographic parameter and radiation technique on the volumetric dose of lung and heart for intact breast radiation...
  48. ncbi request reprint Elective nodal failures are uncommon in medically inoperable patients with Stage I non-small-cell lung carcinoma treated with limited radiotherapy fields
    Jeffrey D Bradley
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 56:342-7. 2003
    ..To review the outcome for 56 Stage I non-small-cell lung cancer treated definitively with three-dimensional conformal radiotherapy (3D-CRT) and to investigate the value of elective nodal irradiation in this patient population...
  49. ncbi request reprint Implementing biologic target volumes in radiation treatment planning for non-small cell lung cancer
    Jeffrey D Bradley
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, St Louis, Missouri, USA
    J Nucl Med 45:96S-101S. 2004
    ..In this report, we will review the literature on PET-based radiation treatment planning, its potential benefits, and future challenges...
  50. ncbi request reprint Positron emission tomography in limited-stage small-cell lung cancer: a prospective study
    Jeffrey D Bradley
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4921 Parkview Place, St Louis, MO 63110, USA
    J Clin Oncol 22:3248-54. 2004
    ....
  51. ncbi request reprint Gross tumor volume, critical prognostic factor in patients treated with three-dimensional conformal radiation therapy for non-small-cell lung carcinoma
    Jeffrey D Bradley
    Radiation Oncology Center, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 52:49-57. 2002
    ..The purpose of this study is to identify prognostic factors in a population of NSCLC patients treated with definitive 3D-CRT...
  52. ncbi request reprint Phase II trial of postoperative adjuvant paclitaxel/carboplatin and thoracic radiotherapy in resected stage II and IIIA non-small-cell lung cancer: promising long-term results of the Radiation Therapy Oncology Group--RTOG 9705
    Jeffrey D Bradley
    Department of Radiation Oncology, Washington University Medical Center, 4921 Parkview Place LL, Mail Stop 90 38 635, St Louis, MO 63110, USA
    J Clin Oncol 23:3480-7. 2005
    ....
  53. ncbi request reprint Comparison of spirometry and abdominal height as four-dimensional computed tomography metrics in lung
    Wei Lu
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 32:2351-7. 2005
    ..By combining these two, a normalization of the drift-free metric to tidal volume may be generated and the overall metric precision may be improved...
  54. ncbi request reprint Novel breathing motion model for radiotherapy
    Daniel A Low
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 63:921-9. 2005
    ..Time is an implicit variable in this model...
  55. ncbi request reprint CT localization of axillary lymph nodes in relation to the humeral head: significance of arm position for radiation therapy planning
    David B Mansur
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Radiother Oncol 77:191-3. 2005
    ..With the arm abducted beyond 55 degrees, humeral head blocking would result in blocking of some of the axillary nodes...
  56. ncbi request reprint Concurrent multimodality image segmentation by active contours for radiotherapy treatment planning
    Issam El Naqa
    Department of Radiation Oncology, School of Medicine, Washington University, St Louis, Missouri 63110, USA
    Med Phys 34:4738-49. 2007
    ....
  57. ncbi request reprint Deblurring of breathing motion artifacts in thoracic PET images by deconvolution methods
    Issam El Naqa
    Department of Radiation Oncology, Washington University, School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 33:3587-600. 2006
    ..Our initial results show that the proposed method provides a feasible framework for improving PET thoracic images, without the need for gated/4-D PET imaging, when 4-D CT is available to estimate tumor motion...
  58. ncbi request reprint A semi-automatic method for peak and valley detection in free-breathing respiratory waveforms
    Wei Lu
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 33:3634-6. 2006
    ..On average for each of the 20 patients, 99% of 307 peaks and valleys were automatically detected in 2.8 s. This method was robust for bellows waveforms with large variations...
  59. ncbi request reprint A method for the reconstruction of four-dimensional synchronized CT scans acquired during free breathing
    Daniel A Low
    Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 30:1254-63. 2003
    ..While still under development, this technology has the potential for revolutionizing the radiotherapy treatment planning for the thorax and upper abdomen...
  60. ncbi request reprint Bronchoscopic implantation of a novel wireless electromagnetic transponder in the canine lung: a feasibility study
    Martin L Mayse
    Division of Pulmonary and Critical Care, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 72:93-8. 2008
    ..Seattle, WA). We evaluated the feasibility and fixation of electromagnetic transponders bronchoscopically implanted in small airways of canine lungs and compared to results using gold markers...
  61. doi request reprint Eliminating inconsistencies in simulation and treatment planning orders in radiation therapy
    Lakshmi Santanam
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
    Int J Radiat Oncol Biol Phys 85:484-91. 2013
    ..To identify deficiencies with simulation and treatment planning orders and to develop corrective measures to improve safety and quality...
  62. doi request reprint Clinical evaluations of an amplitude-based binning algorithm for 4DCT reconstruction in radiation therapy
    Hua Li
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Med Phys 39:922-32. 2012
    ..The purpose of this study was to evaluate the performance of the first commercially available on-line retrospective amplitude-binning algorithm for comparison to the traditional phase-binning algorithm...
  63. ncbi request reprint Clinical-pathologic conference in general thoracic surgery: Cardiac lymphoma
    Richard Battafarano
    Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
    J Thorac Cardiovasc Surg 130:870-4. 2005
  64. pmc Opportunities and challenges in the era of molecularly targeted agents and radiation therapy
    Steven H Lin
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 097, Houston, TX 77030, USA
    J Natl Cancer Inst 105:686-93. 2013
    ....
  65. pmc Predicting radiotherapy outcomes using statistical learning techniques
    Issam El Naqa
    Washington University, Saint Louis, MO, USA
    Phys Med Biol 54:S9-S30. 2009
    ..These models have the capacity to predict on unseen data...
  66. ncbi request reprint Phase II trial of preoperative chemoradiation in patients with localized gastric adenocarcinoma (RTOG 9904): quality of combined modality therapy and pathologic response
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 24:3953-8. 2006
    ..We hypothesized that, in a cooperative group setting, preoperative chemoradiotherapy would induce a 20% pathologic complete response (pathCR) rate. Combined-modality therapy quality, survival, and safety were secondary end points...