Kevin J Black

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Levodopa challenge neuroimaging of levodopa-related mood fluctuations in Parkinson's disease
    Kevin J Black
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Neuropsychopharmacology 30:590-601. 2005
  2. ncbi request reprint "Stop doing that"! Recognizing and managing tics
    Kevin J Black
    Washington University School of Medicine, USA
    Mo Med 105:53-6. 2008
  3. pmc Quantification of indirect pathway inhibition by the adenosine A2a antagonist SYN115 in Parkinson disease
    Kevin J Black
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 30:16284-92. 2010
  4. pmc Prospectively determined impact of type 1 diabetes on brain volume during development
    Dana C Perantie
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Diabetes 60:3006-14. 2011
  5. pmc Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease
    Meghan C Campbell
    Dept of Neurology, Washington University School of Medicine, St Louis, MO, USA
    J Neuropsychiatry Clin Neurosci 24:28-36. 2012
  6. ncbi request reprint Dopaminergic modulation of response inhibition: an fMRI study
    Tamara Hershey
    Psychiatry Department, Washington University School of Medicine, USA
    Brain Res Cogn Brain Res 20:438-48. 2004
  7. pmc Hippocampal volumes in youth with type 1 diabetes
    Tamara Hershey
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Diabetes 59:236-41. 2010
  8. ncbi request reprint Cognitive-pharmacologic functional magnetic resonance imaging in tourette syndrome: a pilot study
    Tamara Hershey
    Department of Psychiatry, Washington University, St Louis, Missouri, USA
    Biol Psychiatry 55:916-25. 2004
  9. ncbi request reprint Intravenous levodopa administration in humans based on a two-compartment kinetic model
    Mollie Gordon
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Neurosci Methods 159:300-7. 2007
  10. pmc Characterization of extrastriatal D2 in vivo specific binding of [¹⁸F](N-methyl)benperidol using PET
    Sarah A Eisenstein
    Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri 63110, USA
    Synapse 66:770-80. 2012

Research Grants

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Levodopa challenge neuroimaging of levodopa-related mood fluctuations in Parkinson's disease
    Kevin J Black
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Neuropsychopharmacology 30:590-601. 2005
    ..The findings require confirmation in larger and better-matched groups...
  2. ncbi request reprint "Stop doing that"! Recognizing and managing tics
    Kevin J Black
    Washington University School of Medicine, USA
    Mo Med 105:53-6. 2008
    ..TS is highly heritable though not yet convincingly associated with a specific gene. Many patients need no specific treatment, but certain medications and behavioral therapies have proven efficacy...
  3. pmc Quantification of indirect pathway inhibition by the adenosine A2a antagonist SYN115 in Parkinson disease
    Kevin J Black
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 30:16284-92. 2010
    ....
  4. pmc Prospectively determined impact of type 1 diabetes on brain volume during development
    Dana C Perantie
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Diabetes 60:3006-14. 2011
    ..However, these studies cannot identify brain regions that change differentially over time depending on the degree of exposure to glycemic extremes...
  5. pmc Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease
    Meghan C Campbell
    Dept of Neurology, Washington University School of Medicine, St Louis, MO, USA
    J Neuropsychiatry Clin Neurosci 24:28-36. 2012
    ..Left DBS improved mood more than right DBS. Right DBS-induced increase in positive mood was related to more medial and dorsal contact locations. These results highlight the functional heterogeneity of the STN...
  6. ncbi request reprint Dopaminergic modulation of response inhibition: an fMRI study
    Tamara Hershey
    Psychiatry Department, Washington University School of Medicine, USA
    Brain Res Cogn Brain Res 20:438-48. 2004
    ..In summary, right parietal and cerebellar regions important in mediating specific aspects of the GNG task were modulated by levodopa, suggesting a region-specific role for dopamine in response inhibition...
  7. pmc Hippocampal volumes in youth with type 1 diabetes
    Tamara Hershey
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Diabetes 59:236-41. 2010
    ..We examined whether hypoglycemia or hyperglycemia experienced during brain development in humans affects hippocampal volumes...
  8. ncbi request reprint Cognitive-pharmacologic functional magnetic resonance imaging in tourette syndrome: a pilot study
    Tamara Hershey
    Department of Psychiatry, Washington University, St Louis, Missouri, USA
    Biol Psychiatry 55:916-25. 2004
    ....
  9. ncbi request reprint Intravenous levodopa administration in humans based on a two-compartment kinetic model
    Mollie Gordon
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Neurosci Methods 159:300-7. 2007
    ..Levodopa significantly reduced serum prolactin and raised serum growth hormone concentrations. Volunteers had no significant side effects...
  10. pmc Characterization of extrastriatal D2 in vivo specific binding of [¹⁸F](N-methyl)benperidol using PET
    Sarah A Eisenstein
    Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri 63110, USA
    Synapse 66:770-80. 2012
    ..Our findings indicate that PET with [¹⁸F]NMB measures specific binding in extrastriatal regions, making it a viable radioligand to study extrastriatal D2R levels in healthy and diseased states...
  11. ncbi request reprint Rapid intravenous loading of levodopa for human research: clinical results
    Kevin J Black
    Department of Psychiatry and APDA Advanced Research Center for Parkinson Disease, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Neurosci Methods 127:19-29. 2003
    ..D.), and produced statistically significant antiparkinsonian benefit (16% mean reduction in a standard rating of parkinsonian motor signs, P<0.0005)...
  12. pmc A possible substrate for dopamine-related changes in mood and behavior: prefrontal and limbic effects of a D3-preferring dopamine agonist
    Kevin J Black
    Departments of Psychiatry, School of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 99:17113-8. 2002
    ....
  13. pmc Motor asymmetry and substantia nigra volume are related to spatial delayed response performance in Parkinson disease
    Erin R Foster
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Brain Cogn 67:1-10. 2008
    ..In conclusion, left motor dysfunction and smaller right SN volume are associated with poorer spatial memory...
  14. ncbi request reprint Atlas template images for nonhuman primate neuroimaging: baboon and macaque
    Kevin J Black
    Departments of Psychiatry, Neurology, and Radiology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Methods Enzymol 385:91-102. 2004
  15. ncbi request reprint Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes
    Dana C Perantie
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Diabetes Care 30:2331-7. 2007
    ..This study is the first to quantify regional brain volume differences in a large sample of youth with diabetes...
  16. ncbi request reprint Asymmetric regional cerebral blood flow in sedated baboons measured by positron emission tomography (PET)
    Jason A Kaufman
    Department of Anthropology, Washington University, St Louis, Missouri 63130, USA
    Am J Phys Anthropol 121:369-77. 2003
    ..Cerebral blood flow itself was uncorrelated with age, and differences between males and females were not significant...
  17. ncbi request reprint Clinical features and comorbidity of mood fluctuations in Parkinson's disease
    Brad A Racette
    Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8111, St Louis, MO 63110, USA
    J Neuropsychiatry Clin Neurosci 14:438-42. 2002
    ..This association remained after removing effects of age and disease duration...
  18. pmc Validity of large-deformation high dimensional brain mapping of the basal ganglia in adults with Tourette syndrome
    Lei Wang
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychiatry Res 154:181-90. 2007
    ..We found no significant volume or shape differences in any of the structures in this small sample of subjects...
  19. pmc A perfusion MRI study of emotional valence and arousal in Parkinson's disease
    Sunsern Limsoontarakul
    Department of Psychiatry, Washington University School of Medicine St Louis, St Louis, MO 63110, USA
    Parkinsons Dis 2011:742907. 2011
    ..Conclusion. This study demonstrates that the temporal stability of perfusion MRI allows within-subject investigations of spontaneous fluctuations in mental state, such as mood, over relatively long-time intervals...
  20. ncbi request reprint The cognitive correlates of functional status: a review from the Committee on Research of the American Neuropsychiatric Association
    Donald R Royall
    Department of Psychiatry, UTHSCSA, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Neuropsychiatry Clin Neurosci 19:249-65. 2007
    ..Better integration of cognitive and functional assessments would offer greater clinical utility. However, psychometric batteries may have to be redesigned to maximize their capacity to capture the variance in functional outcomes...
  21. ncbi request reprint The value of quantitative electroencephalography in clinical psychiatry: a report by the Committee on Research of the American Neuropsychiatric Association
    Kerry L Coburn
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, Georgia 31201, USA
    J Neuropsychiatry Clin Neurosci 18:460-500. 2006
    ..As a clinical laboratory test, qEEG's cautious use is recommended in attentional and learning disabilities of childhood, and in mood and dementing disorders of adulthood...
  22. ncbi request reprint Blood flow imaging of the brain: 50 years experience
    Katherine H Taber
    Veterans Affairs Mid Atlantic Mental Illness Research, Education, and Clinical Center, Salisbury, North Carolina, USA
    J Neuropsychiatry Clin Neurosci 17:441-6. 2005
  23. pmc Cerebral mitochondrial metabolism in early Parkinson's disease
    William J Powers
    Department of Neurology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina 27599 7025, USA
    J Cereb Blood Flow Metab 28:1754-60. 2008
    ..Whether this is the case in early PD and whether it is important in the pathogenesis of PD will require further study...
  24. ncbi request reprint Psychiatric screening for DBS
    Kevin J Black
    Parkinsonism Relat Disord 13:546. 2007
  25. ncbi request reprint Repetitive and impulsive behaviors in treated Parkinson disease
    Kevin J Black
    Neurology 67:1118-9. 2006

Research Grants2

  1. Testing Dopaminergic Function Using Pharmacologic FMRI
    Kevin Black; Fiscal Year: 2003
    ..abstract_text> ..
  2. Dopaminergic Effects on Cortical Function in Tourette's
    Kevin J Black; Fiscal Year: 2010
    ..The significance of this research includes its potential to define an endophenotype for future developmental or genetic studies of TS. ..