David C Beebe


Affiliation: Washington University School of Medicine
Country: USA


  1. Chen Z, Huang J, Liu Y, Dattilo L, Huh S, Ornitz D, et al. FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands. Development. 2014;141:2691-701 pubmed publisher
  2. Huang J, Liu Y, Oltean A, Beebe D. Bmp4 from the optic vesicle specifies murine retina formation. Dev Biol. 2015;402:119-26 pubmed publisher
    ..Differences in the signaling pathways required for specification of the retina and retinal pigmented epithelium in chicken and mouse embryos suggest major changes in signaling during the evolution of the vertebrate eye. ..
  3. Beebe D, Garcia C, Wang X, Rajagopal R, Feldmeier M, Kim J, et al. Contributions by members of the TGFbeta superfamily to lens development. Int J Dev Biol. 2004;48:845-56 pubmed
    ..This approach may also provide a useful way to define the downstream pathways that are activated by these receptors during the development of the lens and other tissues. ..
  4. Beebe D, Holekamp N, Siegfried C, Shui Y. Vitreoretinal influences on lens function and cataract. Philos Trans R Soc Lond B Biol Sci. 2011;366:1293-300 pubmed publisher
    ..Oxygen reaches the lens nucleus, increasing protein oxidation and aggregation and leading to nuclear cataract. We suggest that maintaining low pO(2) around the lens should prevent the formation of nuclear cataracts...