R H Baloh

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi The GDNF family ligands and receptors - implications for neural development
    R H Baloh
    Departments of Pathology and Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Curr Opin Neurobiol 10:103-10. 2000
  2. ncbi Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex
    R H Baloh
    Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 21:1291-302. 1998
  3. ncbi Expression of neurturin, GDNF, and their receptors in the adult mouse CNS
    J P Golden
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Comp Neurol 398:139-50. 1998
  4. ncbi GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival
    M G Tansey
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 25:611-23. 2000
  5. pmc GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family
    R H Baloh
    Department of Pathology and Internal Medicine, Molecular Biology, and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8118, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 95:5801-6. 1998
  6. ncbi TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret
    R H Baloh
    Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 18:793-802. 1997
  7. ncbi Persephin, a novel neurotrophic factor related to GDNF and neurturin
    J Milbrandt
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 20:245-53. 1998

Collaborators

Detail Information

Publications7

  1. ncbi The GDNF family ligands and receptors - implications for neural development
    R H Baloh
    Departments of Pathology and Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Curr Opin Neurobiol 10:103-10. 2000
    ..The results of such analyses reveal numerous similarities and potential overlaps in the way the GDNF and the nerve growth factor (NGF) families regulate development of the peripheral nervous system...
  2. ncbi Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex
    R H Baloh
    Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 21:1291-302. 1998
    ....
  3. ncbi Expression of neurturin, GDNF, and their receptors in the adult mouse CNS
    J P Golden
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Comp Neurol 398:139-50. 1998
    ..NTN and GDNF are expressed in targets of neurons that express GF receptors. The pattern of GF factor and receptor expression in the adult brain suggests a role for these factors in maintaining neuronal circuits in the mature CNS...
  4. ncbi GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival
    M G Tansey
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 25:611-23. 2000
    ..Therefore, proper membrane localization of RET via interaction with a raft-localized, GPI-linked coreceptor is of fundamental importance in GFL signaling...
  5. pmc GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family
    R H Baloh
    Department of Pathology and Internal Medicine, Molecular Biology, and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8118, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 95:5801-6. 1998
    ..Fibroblasts expressing Ret and GFRalpha3 do not respond to any of the known members of the GDNF family, suggesting that GFRalpha3 interacts with an unknown ligand or requires a different or additional signaling protein to function...
  6. ncbi TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret
    R H Baloh
    Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 18:793-802. 1997
    ..Comparative analysis of TrnR1, TrnR2, and Ret expression indicates that multiple receptor complexes, capable of mediating GDNF and NTN signaling, exist in vivo...
  7. ncbi Persephin, a novel neurotrophic factor related to GDNF and neurturin
    J Milbrandt
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 20:245-53. 1998
    ..Fibroblasts transfected with Ret and one of the coreceptors GFRalpha-1 or GFRalpha-2 do not respond to persephin, suggesting that persephin utilizes additional, or different, receptor components than GDNF and NTN...