Paul Austin

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries
    Scott R Manson
    Department of Surgery, Division of Pediatric Urology, Washington University, 4990 Children s Place, St Louis, MO 63110, USA
    Am J Physiol Renal Physiol 301:F1293-302. 2011
  2. doi request reprint Circumcision
    Paul F Austin
    Division of Urologic Surgery, Washington University in St Louis School of Medicine, St Louis Children s Hospital, St Louis, Missouri, USA
    Curr Opin Urol 20:318-22. 2010
  3. doi request reprint The role of alpha blockers in children with dysfunctional voiding
    Paul Austin
    Pediatric Urology, St Louis Children s Hospital, Washington University School of Medicine, St Louis, Missouri, USA
    ScientificWorldJournal 9:880-3. 2009
  4. doi request reprint Combination therapy with desmopressin and an anticholinergic medication for nonresponders to desmopressin for monosymptomatic nocturnal enuresis: a randomized, double-blind, placebo-controlled trial
    Paul F Austin
    Division of Urology, Washington University School of Medicine, St Louis Children s Hospital, St Louis, Missouri, USA
    Pediatrics 122:1027-32. 2008
  5. ncbi request reprint Inhibition of mitogenic signaling and induction of apoptosis in human bladder smooth muscle cells treated with doxazosin
    Paul F Austin
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 172:1662-5; discussion 1666. 2004
  6. doi request reprint Correlation of prenatal and postnatal ultrasound findings with the incidence of vesicoureteral reflux in children with fetal renal pelvic dilatation
    Douglas E Coplen
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 180:1631-4; discussion 1634. 2008
  7. pmc Enuresis is a common and persistent problem among children and young adults with sickle cell anemia
    Joshua J Field
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 72:81-4. 2008
  8. ncbi request reprint Enuresis and dysfunctional elimination
    Paul F Austin
    Washington University School of Medicine, St Louis Children s Hospital, USA
    Mo Med 104:421-4. 2007
  9. ncbi request reprint The magnitude of fetal renal pelvic dilatation can identify obstructive postnatal hydronephrosis, and direct postnatal evaluation and management
    Douglas E Coplen
    Division of Urology, and Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 176:724-7; discussion 727. 2006
  10. ncbi request reprint Outcome analysis of prenatally detected ureteroceles associated with multicystic dysplasia
    Douglas E Coplen
    Division of Urology, St Louis Children s Hospital and Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 172:1637-9; discussion 1639. 2004

Research Grants

Collaborators

Detail Information

Publications17

  1. pmc Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries
    Scott R Manson
    Department of Surgery, Division of Pediatric Urology, Washington University, 4990 Children s Place, St Louis, MO 63110, USA
    Am J Physiol Renal Physiol 301:F1293-302. 2011
    ..Accordingly, renal recovery from obstructive uropathies may be optimized through timely intervention and adjuvant approaches to restore BMP-7 activity...
  2. doi request reprint Circumcision
    Paul F Austin
    Division of Urologic Surgery, Washington University in St Louis School of Medicine, St Louis Children s Hospital, St Louis, Missouri, USA
    Curr Opin Urol 20:318-22. 2010
    ..Ancillary studies from these trials and others have emerged with more data on further public health benefits. We review the findings of these new trials as well as new studies pertaining to male circumcision...
  3. doi request reprint The role of alpha blockers in children with dysfunctional voiding
    Paul Austin
    Pediatric Urology, St Louis Children s Hospital, Washington University School of Medicine, St Louis, Missouri, USA
    ScientificWorldJournal 9:880-3. 2009
    ..Long-term follow-up and further investigation are warranted in order to validate the role of alpha blocker therapy in pediatric dysfunctional voiding...
  4. doi request reprint Combination therapy with desmopressin and an anticholinergic medication for nonresponders to desmopressin for monosymptomatic nocturnal enuresis: a randomized, double-blind, placebo-controlled trial
    Paul F Austin
    Division of Urology, Washington University School of Medicine, St Louis Children s Hospital, St Louis, Missouri, USA
    Pediatrics 122:1027-32. 2008
    ..To evaluate this treatment strategy, we examined the efficacy of combination therapy for primary nocturnal enuresis in desmopressin-nonresponders...
  5. ncbi request reprint Inhibition of mitogenic signaling and induction of apoptosis in human bladder smooth muscle cells treated with doxazosin
    Paul F Austin
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 172:1662-5; discussion 1666. 2004
    ..However, doxazosin has been shown to inhibit proliferation and induce apoptosis in nonbladder smooth muscle. Consequently, we examined the effects of doxazosin on human bladder smooth muscle cell (SMC) proliferation and apoptosis...
  6. doi request reprint Correlation of prenatal and postnatal ultrasound findings with the incidence of vesicoureteral reflux in children with fetal renal pelvic dilatation
    Douglas E Coplen
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 180:1631-4; discussion 1634. 2008
    ..We report an evaluation of fetal renal pelvic dilatation and postnatal sonographic features with the incidence of vesicoureteral reflux...
  7. pmc Enuresis is a common and persistent problem among children and young adults with sickle cell anemia
    Joshua J Field
    Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 72:81-4. 2008
    ..The objectives of this study were to describe the prevalence of enuresis and nocturia among children and young adults with SCA and determine the relationship, if any, between these symptoms and SCA-related morbidity...
  8. ncbi request reprint Enuresis and dysfunctional elimination
    Paul F Austin
    Washington University School of Medicine, St Louis Children s Hospital, USA
    Mo Med 104:421-4. 2007
    ..Constipation is frequently associated and can impair successful therapy. A primary care physician can successfully treat most enuresis but severe dysfunctions or refractory patients need a referral to a specialist...
  9. ncbi request reprint The magnitude of fetal renal pelvic dilatation can identify obstructive postnatal hydronephrosis, and direct postnatal evaluation and management
    Douglas E Coplen
    Division of Urology, and Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 176:724-7; discussion 727. 2006
    ..Up to 1% of prenatal ultrasounds will detect fetal renal pelvic dilatation. We sought to evaluate and determine whether fetal renal pelvic measurements may appropriately direct prenatal counseling and postnatal evaluation and management...
  10. ncbi request reprint Outcome analysis of prenatally detected ureteroceles associated with multicystic dysplasia
    Douglas E Coplen
    Division of Urology, St Louis Children s Hospital and Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 172:1637-9; discussion 1639. 2004
    ..We assessed the outcome of a nonoperative approach in infants with prenatally detected ureteroceles associated with multicystic dysplasia...
  11. ncbi request reprint Vesicoureteral reflux and clinical outcomes in infants with prenatally detected hydronephrosis
    M Michele Brophy
    Division of Pediatric Urology, St Louis Children s Hospital and Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 168:1716-9; discussion 1719. 2002
    ..We evaluate the incidence of vesicoureteral reflux and urinary tract infections in infants with prenatally detected hydronephrosis...
  12. ncbi request reprint Pediatric nephrolithiasis: does treatment affect renal growth?
    Karen Reisiger
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 69:1190-4. 2007
    ..Likewise, no long-term data regarding renal growth after ureteroscopy or percutaneous nephrolithotomy have been published. We studied the effect of urolithiasis on renal growth in our pediatric patient population...
  13. ncbi request reprint Prenatal diagnosis and neonatal management of congenital urethral diverticulum
    Douglas E Coplen
    Division of Pediatric Urology, St Louis Children s Hospital and Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 177:2330-2. 2007
    ..We present a series of male neonates with prenatally detected anterior urethral diverticula and discuss postnatal management...
  14. doi request reprint The incidence of disorders of sexual differentiation and chromosomal abnormalities of cryptorchidism and hypospadias stratified by meatal location
    Michael J Cox
    Division of Pediatric Urology, Washington University, St Louis Children s Hospital, St Louis, Missouri, USA
    J Urol 180:2649-52; discussion 2652. 2008
    ..Therefore, we analyzed the incidence of chromosomal abnormalities in patients with distal or proximal hypospadias and concomitant cryptorchidism...
  15. ncbi request reprint Lipopolysaccharide and inflammatory cytokines cause an inducible nitric oxide synthase-dependent bladder smooth muscle fibrotic response
    Paul F Austin
    Division of Urology, St Louis Children s Hospital, Missouri, USA
    J Urol 170:645-8. 2003
    ..Inducible nitric oxide synthase (iNOS) has been shown to mediate the fibrotic response to inflammation in other tissues. We determined if iNOS could be involved in the fibrotic response to recurrent UTI...
  16. doi request reprint The physiological significance of p27(KIP1) expression in detrusor function
    Robert A Niederhoff
    Division of Pediatric Urology, Department of Surgery, St Louis Children s Hospital, Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 184:1686-91. 2010
    ..We investigated the role of p27(KIP1) in the structure and function of the detrusor layer of the bladder wall...
  17. ncbi request reprint Alpha blocker therapy for children with dysfunctional voiding and urinary retention
    Mark P Cain
    Department of Urology, Indiana University School of Medicine, Indianapolis, USA
    J Urol 170:1514-5; discussion 1516-7. 2003
    ..We evaluated the safety and efficacy of using selective alpha blocker therapy for children with uncomplicated voiding dysfunction and underlying poor bladder emptying...

Research Grants1

  1. Regulation of Bladder Smooth Muscle Hyperplasia
    Paul Austin; Fiscal Year: 2007
    ..Work of this nature may decrease the morbidity and mortality that is caused by bladder outlet obstruction. ..