Gerald Andriole

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Modeling and Analysis of Gleason Score 8-10 Prostate Cancers in the REDUCE Study
    Gerald L Andriole
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo Electronic address
    Urology 84:393-9. 2014
  2. ncbi request reprint Update of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    Gerald L Andriole
    Division of Urologic Surgery, Washington University in Saint Louis, St Louis, MO, USA
    Recent Results Cancer Res 202:53-7. 2014
  3. pmc The effect of increasing doses of saw palmetto fruit extract on serum prostate specific antigen: analysis of the CAMUS randomized trial
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 189:486-92. 2013
  4. pmc Overdiagnosis of prostate cancer
    Gurdarshan S Sandhu
    Division of Urologic Surgery, Washington University School of Medicine, 4960 Children s Place, St Louis, MO 63110, USA
    J Natl Cancer Inst Monogr 2012:146-51. 2012
  5. ncbi request reprint The prostate, lung, colon, and ovarian (PLCO) cancer screening trial: Status and promise
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, Washington University in St Louis, 4960 Children s Place, Campus Box 8242, St Louis, MO 63110, USA
    Urol Oncol 22:358-61. 2004
  6. ncbi request reprint Chemoprevention of prostate cancer in men at high risk: rationale and design of the reduction by dutasteride of prostate cancer events (REDUCE) trial
    Gerald Andriole
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 172:1314-7. 2004
  7. ncbi request reprint Effect of dutasteride on the risk of prostate cancer
    Gerald L Andriole
    Division of Urology, Washington University School of Medicine in St Louis, St Louis, MO 63110, USA
    N Engl J Med 362:1192-202. 2010
  8. doi request reprint The effect of dutasteride on the usefulness of prostate specific antigen for the diagnosis of high grade and clinically relevant prostate cancer in men with a previous negative biopsy: results from the REDUCE study
    Gerald L Andriole
    Department of Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri 63110, USA
    J Urol 185:126-31. 2011
  9. doi request reprint Overview of pivotal studies for prostate cancer risk reduction, past and present
    Gerald L Andriole
    Division of Urology, Department of Surgery, Washington University School of Medicine, Barnes Jewish Hospital, Siteman Cancer Center, St Louis, Missouri 63110, USA
    Urology 73:S36-43. 2009
  10. doi request reprint Is there a better way to biopsy the prostate? Prospects for a novel transrectal systematic biopsy approach
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 70:22-6. 2007

Detail Information

Publications65

  1. ncbi request reprint Modeling and Analysis of Gleason Score 8-10 Prostate Cancers in the REDUCE Study
    Gerald L Andriole
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo Electronic address
    Urology 84:393-9. 2014
    ....
  2. ncbi request reprint Update of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    Gerald L Andriole
    Division of Urologic Surgery, Washington University in Saint Louis, St Louis, MO, USA
    Recent Results Cancer Res 202:53-7. 2014
    ..Thus far, annual screening in this study has not been associated with a reduction of prostate cancer specific mortality. The potential explanations for this finding are reviewed. ..
  3. pmc The effect of increasing doses of saw palmetto fruit extract on serum prostate specific antigen: analysis of the CAMUS randomized trial
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 189:486-92. 2013
    ..We determined whether higher doses of saw palmetto as studied in the CAMUS (Complementary and Alternative Medicine for Urologic Symptoms) trial affect serum prostate specific antigen levels...
  4. pmc Overdiagnosis of prostate cancer
    Gurdarshan S Sandhu
    Division of Urologic Surgery, Washington University School of Medicine, 4960 Children s Place, St Louis, MO 63110, USA
    J Natl Cancer Inst Monogr 2012:146-51. 2012
    ..Future prospects to prevent overtreatment, including better biopsy and molecular characterization of newly diagnosed cancer and the role of active surveillance, are discussed...
  5. ncbi request reprint The prostate, lung, colon, and ovarian (PLCO) cancer screening trial: Status and promise
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, Washington University in St Louis, 4960 Children s Place, Campus Box 8242, St Louis, MO 63110, USA
    Urol Oncol 22:358-61. 2004
    ..Together, the data derived from the intervention and control arms and material in the biorepository provide a valuable resource to allow identification and testing of novel biomarkers for human disease...
  6. ncbi request reprint Chemoprevention of prostate cancer in men at high risk: rationale and design of the reduction by dutasteride of prostate cancer events (REDUCE) trial
    Gerald Andriole
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 172:1314-7. 2004
    ..It represents a biologically plausible target for chemoprevention through the inhibition of 5alpha-reductase isoenzymes...
  7. ncbi request reprint Effect of dutasteride on the risk of prostate cancer
    Gerald L Andriole
    Division of Urology, Washington University School of Medicine in St Louis, St Louis, MO 63110, USA
    N Engl J Med 362:1192-202. 2010
    ..We conducted a study to determine whether dutasteride reduces the risk of incident prostate cancer, as detected on biopsy, among men who are at increased risk for the disease...
  8. doi request reprint The effect of dutasteride on the usefulness of prostate specific antigen for the diagnosis of high grade and clinically relevant prostate cancer in men with a previous negative biopsy: results from the REDUCE study
    Gerald L Andriole
    Department of Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri 63110, USA
    J Urol 185:126-31. 2011
    ..We assessed whether dutasteride enhances the usefulness of total prostate specific antigen for diagnosing clinically significant prostate cancer...
  9. doi request reprint Overview of pivotal studies for prostate cancer risk reduction, past and present
    Gerald L Andriole
    Division of Urology, Department of Surgery, Washington University School of Medicine, Barnes Jewish Hospital, Siteman Cancer Center, St Louis, Missouri 63110, USA
    Urology 73:S36-43. 2009
    ....
  10. doi request reprint Is there a better way to biopsy the prostate? Prospects for a novel transrectal systematic biopsy approach
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 70:22-6. 2007
    ..Its reproducibility from operator to operator suggests that it may be useful for guiding rebiopsy of specific locations within the prostate and for providing targeted focal prostate cancer therapy...
  11. doi request reprint Obesity is associated with increased prostate growth and attenuated prostate volume reduction by dutasteride
    Roberto L Muller
    Division of Urologic Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA
    Eur Urol 63:1115-21. 2013
    ..Although obesity has been associated with larger prostate volumes (PV), few studies have actually investigated whether obesity enhances PV growth, especially among men using 5α-reductase inhibitors...
  12. ncbi request reprint Dihydrotestosterone and the prostate: the scientific rationale for 5alpha-reductase inhibitors in the treatment of benign prostatic hyperplasia
    Gerald Andriole
    Division of Urological Surgery, Washington University in St Louis, St Louis, Missouri 63110, USA
    J Urol 172:1399-403. 2004
    ..We reviewed the physiological and pathogenic role of dihydrotestosterone (DHT), evidence for the beneficial effects of decreasing DHT through 5alpha-reductase inhibition and the effects of altering the androgen balance with these agents...
  13. ncbi request reprint Relating biopsy and clinical variables to radical prostatectomy findings: can insignificant and advanced prostate cancer be predicted in a screening population?
    Jason W Anast
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 64:544-50. 2004
    ....
  14. doi request reprint Serum testosterone and dihydrotestosterone and prostate cancer risk in the placebo arm of the Reduction by Dutasteride of Prostate Cancer Events trial
    Roberto L Muller
    Division of Urologic Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA
    Eur Urol 62:757-64. 2012
    ..Androgens may affect prostate-specific antigen (PSA) levels, thereby influencing biopsy recommendations. Also, androgens may stimulate prostate growth at very low levels with no additional effects at higher levels (saturation model)...
  15. ncbi request reprint The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge
    Gerald Andriole
    Division of Urologic Surgery, School of Medicine, Washington University St Louis, 4960 Children s Place, St Louis, MO 63110, USA
    J Urol 174:2098-104. 2005
    ..However, Gleason score 7-10 tumors were significantly more common in the finasteride vs the placebo group. We considered data on the effects of 5ARIs on prostate cancer natural history and detection...
  16. ncbi request reprint Emerging drug therapies for benign prostatic hyperplasia
    Travis L Bullock
    Division of Urology, Washington University School of Medicine, St Louis, MO 63110, USA
    Expert Opin Emerg Drugs 11:111-23. 2006
    ..The aim of this review is to examine current pharmacotherapies as well as to highlight emerging drugs that may improve our treatment of patients with LUTS secondary to BPH...
  17. ncbi request reprint Prostate-specific antigen density predicts adverse pathology and increased risk of biochemical failure
    Mohamed H Radwan
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 69:1121-7. 2007
    ....
  18. ncbi request reprint Clinical usefulness of serum prostate specific antigen for the detection of prostate cancer is preserved in men receiving the dual 5alpha-reductase inhibitor dutasteride
    Gerald L Andriole
    Division of Urologic Surgery, Washington University, St Louis, Missouri 63110, USA
    J Urol 175:1657-62. 2006
    ..We determined whether the decrease in serum PSA seen with 5alpha-reductase inhibitors affects the clinical usefulness of PSA for prostate cancer screening using data from 2 dutasteride benign prostatic hyperplasia studies...
  19. ncbi request reprint Laparoscopic partial nephrectomy for renal masses: effect of tumor location
    Ramakrishna Venkatesh
    Division of Urology, Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 67:1169-74; discussion 1174. 2006
    ..To report our single institutional experience of laparoscopic partial nephrectomy (LPN) for enhancing renal masses and evaluate outcomes and histopathologic findings with respect to the location of the renal mass...
  20. ncbi request reprint Safety and tolerability of the dual 5alpha-reductase inhibitor dutasteride in the treatment of benign prostatic hyperplasia
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, 4960 Children s Place, Campus Box 8242, St Louis, MO 63110, USA
    Eur Urol 44:82-8. 2003
    ..The objective of this paper is to examine safety and tolerability data from a number of recently completed clinical trials with the novel, dual 5alpha-reductase inhibitor, dutasteride...
  21. pmc Prospective randomized comparison of cutting and dilating disposable trocars for access during laparoscopic renal surgery
    Ramakrishna Venkatesh
    Washington University School of Medicine, Division of Urology, St Louis, Missouri 63110, USA
    JSLS 11:198-203. 2007
    ..More recently, trocars applying tissue dilation have been used that create a smaller defect, seldom requiring fascial wound closure. Four 12-mm commercially available single-use trocar designs were evaluated for postoperative pain...
  22. ncbi request reprint Evaluation of a novel precision template-guided biopsy system for detecting prostate cancer
    Ifeanyichukwu I Megwalu
    Division of Urology, Washington University School of Medicine, St Louis, MO 63105, USA
    BJU Int 102:546-50. 2008
    ....
  23. ncbi request reprint Prostate cancer diagnosis
    Peter A Humphrey
    Washington University School of Medicine in St Louis, USA
    Mo Med 107:107-12. 2010
    ..This article reviews clinical and pathological approaches to prostate cancer diagnosis, with a focus on clinically localized disease and needle biopsy diagnosis...
  24. doi request reprint Update on chemoprevention for prostate cancer
    Seth A Strope
    Division of Urology, Washington University, 4960 Children s Place, Saint Louis, MO 63110, USA
    Curr Opin Urol 20:194-7. 2010
    ..Interest in prostate cancer prevention and risk reduction continues among both patients and clinicians. Recent studies on primary and secondary prevention of prostate cancer will be addressed...
  25. pmc Risk of urinary incontinence following prostatectomy: the role of physical activity and obesity
    Kathleen Y Wolin
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 183:629-33. 2010
    ..We evaluated the association of obesity and lack of physical activity with urinary incontinence in a sample of men who had undergone radical prostatectomy...
  26. ncbi request reprint Patterns of multiple recurrences of superficial (Ta/T1) transitional cell carcinoma of bladder and effects of clinicopathologic and biochemical factors
    Yan Yan
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cancer 95:1239-46. 2002
    ....
  27. ncbi request reprint Pure laparoscopic radical heminephrectomy and partial isthmusectomy for renal cell carcinoma in a horseshoe kidney: case report and technical considerations
    Sam B Bhayani
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 66:880. 2005
    ..Preoperative angiography may aid surgical planning. A pure transperitoneal approach to cancer surgery of the horseshoe kidney is effective...
  28. ncbi request reprint Prostate Cancer Screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized trial
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Natl Cancer Inst 97:433-8. 2005
    ..We describe the population enrolled in the PLCO trial, their baseline PSA and DRE screening results, and diagnostic follow-up results during the first year of follow-up...
  29. ncbi request reprint 11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse
    Nobuyuki Oyama
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Boulevard, St Louis, MO 63110, USA
    J Nucl Med 44:549-55. 2003
    ..We also compared the reliability of AC PET in detecting recurrent prostate cancer with that of PET with (18)F-FDG...
  30. doi request reprint Serum prostate-specific antigen hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    Robert L Grubb
    Division of Urologic Surgery, Washington University School of Medicine, 4960 Children s Place, Campus Box 8242, St Louis, MO 63110, USA
    Cancer Epidemiol Biomarkers Prev 18:748-51. 2009
    ..We examined this hypothesis in a cohort of men enrolled in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial...
  31. pmc Mortality results from a randomized prostate-cancer screening trial
    Gerald L Andriole
    Washington University School of Medicine, St Louis, USA
    N Engl J Med 360:1310-9. 2009
    ..This is the first report from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial on prostate-cancer mortality...
  32. doi request reprint Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: update on findings from the initial four rounds of screening in a randomized trial
    Robert L Grubb
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    BJU Int 102:1524-30. 2008
    ....
  33. ncbi request reprint Renal hypothermia achieved by retrograde endoscopic cold saline perfusion: technique and initial clinical application
    Jaime Landman
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    Urology 61:1023-5. 2003
    ..The technique requires no novel equipment or special surgical skills. This method can be applied to patients undergoing open or laparoscopic complex renal ablative and reconstructive procedures that require renal hypothermia...
  34. ncbi request reprint Use of gelatin matrix to rapidly repair diaphragmatic injury during laparoscopy
    Sam B Bhayani
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 60:514. 2002
    ..The presented case and technique should be considered in selected small diaphragmatic injuries...
  35. ncbi request reprint Can preoperative PSA doubling time and PSA velocity predict outcomes following radical prostatectomy?
    Robert L Grubb
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Nat Clin Pract Urol 3:306-7. 2006
  36. ncbi request reprint Radiation therapy for increasing prostate-specific antigen levels after radical prostatectomy
    Carlos A Perez
    Department of Radiation Oncology, Mallinckrodt, Institute of Radiology, St Louis, MO 63108, USA
    Clin Prostate Cancer 1:235-41. 2003
    ..Prostate bed irradiation is an effective treatment in a significant proportion of patients who present with a biochemical failure after radical prostatectomy...
  37. ncbi request reprint Managing the local complications of locally advanced prostate cancer
    Jason W Anast
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Curr Urol Rep 8:211-6. 2007
    ..Surgical intervention for locally advanced prostate cancer can provide significant improvement in quality of life and should not be restricted to patients who have curable disease...
  38. ncbi request reprint Laparoscopic partial nephrectomy with a novel electrosurgical snare in a porcine model
    William C Collyer
    Division of Urology, Washington University School of Medicine, St Louis, Missouri, USA
    J Endourol 16:673-9. 2002
    ..We evaluated the safety and efficacy of laparoscopic partial nephrectomy with an arcing-gap electrosurgical snare in a porcine model...
  39. ncbi request reprint Application of a fixed retractor system to facilitate laparoscopic radical prostatectomy
    Jaime Landman
    Department of Surgery, Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Urol 171:783-5. 2004
    ..We report application of a fixed retractor system for reduction of the steep Trendelenberg position required to achieve deep pelvic access for laparoscopic radical prostatectomy...
  40. doi request reprint Prostate cancer: to screen or not to screen?
    Alex Shteynshlyuger
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, Barnes Jewish Hospital, Siteman Cancer Center, 4960 Children s Place, Campus Box 8242, St Louis, MO 63110, USA
    Urol Clin North Am 37:1-9, Table of Contents. 2010
    ..Efforts to improve screening with better markers and more selective treatment may make population-based screening more effective...
  41. ncbi request reprint Single-setting bilateral laparoscopic renal surgery: assessment of single-stage procedure
    Karen Reisiger
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 65:892-7; discussion 897. 2005
    ..Little has been reported on patient outcome, morbidity, and mortality of bilateral laparoscopic single-stage procedures...
  42. ncbi request reprint Surgical treatment of renal neoplasia: evolving toward a laparoscopic standard of care
    Sam B Bhayani
    Division of Urology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 62:821-6. 2003
    ..To determine the extent to which laparoscopy has replaced open surgery for renal malignancy...
  43. ncbi request reprint Prevention of benign prostatic hyperplasia disease
    Leonard S Marks
    Urological Sciences Research Foundation and Department of Urology, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90232, USA
    J Urol 176:1299-306. 2006
    ..We reviewed the evidence that benign prostatic hyperplasia is a progressive condition and men at risk for benign prostatic hyperplasia disease can be identified, treated and protected to a meaningful extent regardless of symptom status...
  44. ncbi request reprint Benign prostatic hyperplasia: a progressive disease of aging men
    Mark Emberton
    Institute of Urology and Nephrology, University College, London, United Kingdom
    Urology 61:267-73. 2003
  45. ncbi request reprint Long-term 6-year experience with finasteride in patients with benign prostatic hyperplasia
    Franklin C Lowe
    Department of Urology, Saint Luke s Roosevelt Hospital Center, New York, NY 10019, USA
    Urology 61:791-6. 2003
    ..To summarize the 6-year clinical trial data with finasteride. Benign prostatic hyperplasia is a chronic and progressive disease and therefore assessment of long-term safety and efficacy is important...
  46. ncbi request reprint The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia
    John D McConnell
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    N Engl J Med 349:2387-98. 2003
    ..The long-term effect of these drugs, singly or combined, on the risk of clinical progression is unknown...
  47. ncbi request reprint Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk
    Victoria A Kirsh
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    J Natl Cancer Inst 98:245-54. 2006
    ....
  48. ncbi request reprint High-grade prostate cancer in the Prostate Cancer Prevention Trial: fact or artifact?
    Gerald L Andriole
    J Natl Cancer Inst 99:1355-6. 2007
  49. ncbi request reprint The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: a review and clinical recommendations
    Leonard S Marks
    Department of Urology, School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    J Urol 176:868-74. 2006
    ....
  50. ncbi request reprint Repeat prostate biopsy in the prostate, lung, colorectal and ovarian cancer screening trial
    Paul F Pinsky
    Division of Cancer Prevention, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    BJU Int 99:775-9. 2007
    ..To determine patterns of repeat prostate biopsy in a cohort of men undergoing prostate cancer screening who have a negative initial biopsy...
  51. ncbi request reprint Prostate biopsy following a positive screen in the prostate, lung, colorectal and ovarian cancer screening trial
    Paul F Pinsky
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Urol 173:746-50; discussion 750-1. 2005
    ..Followup of positive screens in PLCO is done by subject personal physicians and it is outside of trial control. We describe the pattern of prostate biopsy in men with positive screens in PLCO...
  52. doi request reprint Group consensus reports from the Consensus Conference on Focal Treatment of Prostatic Carcinoma, Celebration, Florida, February 24, 2006
    David G Bostwick
    Bostwick Laboratories, Richmond, Virginia 23060, USA
    Urology 70:42-4. 2007
  53. ncbi request reprint The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate
    Kenneth A Iczkowski
    Department of Pathology and Laboratory Medicine, Veterans Affairs Medical Center, Gainesville, Florida 32608 1197, USA
    Urology 65:76-82. 2005
    ..To perform the first evaluation of the effects of the 5-alpha-reductase inhibitor class of drugs on cancer histopathologic features at radical prostatectomy in a placebo-controlled multicenter trial...
  54. ncbi request reprint Multiple loci identified in a genome-wide association study of prostate cancer
    Gilles Thomas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nat Genet 40:310-5. 2008
    ..Our findings point to multiple loci with moderate effects associated with susceptibility to prostate cancer that, taken together, in the future may predict high risk in select individuals...
  55. ncbi request reprint Prostate specific antigen based prostate cancer screening: accumulating evidence of efficacy but persistent uncertainty
    Gerald L Andriole
    J Urol 174:413-4. 2005
  56. ncbi request reprint The effect of finasteride in men with benign prostatic hyperplasia. 1992
    Gleen J Gormley
    J Urol 167:1102-7; discussion 1108. 2002
  57. ncbi request reprint Prostate volume and prostate-specific antigen levels in men enrolled in a large screening trial
    Paul F Pinsky
    Division of Cancer Prevention, National Cancer Institute, Bethedsa, Maryland, USA
    Urology 68:352-6. 2006
    ..Here we examine the relationship between prostate volume and PSA level in a large, geographically diverse sample of men undergoing prostate cancer screening...
  58. pmc Serum selenium and risk of prostate cancer-a nested case-control study
    Ulrike Peters
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Clin Nutr 85:209-17. 2007
    ..Interrelations with other antioxidative agents and oxidative stressors, such as smoking, are poorly understood...
  59. doi request reprint Endogenous sex hormones and the risk of prostate cancer: a prospective study
    Jocelyn M Weiss
    Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD, USA
    Int J Cancer 122:2345-50. 2008
    ..T:SHBG ratio was related to risk in this older population of men, but the significance of this ratio in steroidal biology is unclear. (c) 2008 Wiley-Liss, Inc...
  60. ncbi request reprint Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
    Meredith Yeager
    SAIC Frederick, National Cancer Institute NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Nat Genet 39:645-9. 2007
    ..We estimate that the population attributable risk of the new locus, marked by rs6983267, is higher than the locus marked by rs1447295 (21% versus 9%)...
  61. ncbi request reprint RNASEL Arg462Gln polymorphism and prostate cancer in PLCO
    Sarah E Daugherty
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Prostate 67:849-54. 2007
    ..The relationship of this variant to sporadic prostate cancer remains uncertain...
  62. ncbi request reprint A prospective study of meat and meat mutagens and prostate cancer risk
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Res 65:11779-84. 2005
    ..01-1.61). In conclusion, very well done meat was positively associated with prostate cancer risk. In addition, this study lends epidemiologic support to the animal studies, which have implicated PhIP as a prostate carcinogen...
  63. ncbi request reprint Polymorphic variants in PTGS2 and prostate cancer risk: results from two large nested case-control studies
    Kim N Danforth
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 29:568-72. 2008
    ....
  64. ncbi request reprint Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007
    ..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
  65. doi request reprint TNF polymorphisms and prostate cancer risk
    Kim N Danforth
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20852, USA
    Prostate 68:400-7. 2008
    ..Inflammation has been hypothesized to increase prostate cancer risk. Tumor necrosis factor (TNF) is an important mediator of the inflammatory process, but the relationship between TNF variants and prostate cancer remains unclear...