Beau M Ances

Summary

Affiliation: Washington University
Country: USA

Publications

  1. pmc Combination antiretroviral therapy modulates the blood oxygen level-dependent amplitude in human immunodeficiency virus-seropositive patients
    Beau M Ances
    Department of Neurology, Washington University in St Louis, St Louis, MO 63110, USA
    J Neurovirol 14:418-24. 2008
  2. pmc Alzheimer disease family history impacts resting state functional connectivity
    Liang Wang
    Department of Neurology, Washington University in Saint Louis, Saint Louis, MO 63110, USA
    Ann Neurol 72:571-7. 2012
  3. pmc Role of metabolic syndrome components in human immunodeficiency virus-associated stroke
    Beau M Ances
    Department of Neurology, Washington University in St Louis, St Louis, Missouri 63110, USA
    J Neurovirol 15:249-56. 2009
  4. pmc Pathways to neurodegeneration: effects of HIV and aging on resting-state functional connectivity
    Jewell B Thomas
    Department of Neurology, Washington University School of Medicine, St Louis, MO, USA
    Neurology 80:1186-93. 2013
  5. pmc HIV and chronic methamphetamine dependence affect cerebral blood flow
    Beau M Ances
    Department of Neurology, Washington University in St Louis, 660 South Euclid Ave, Box 08111, St Louis, MO 63110, USA
    J Neuroimmune Pharmacol 6:409-19. 2011
  6. pmc Functional connectivity and graph theory in preclinical Alzheimer's disease
    Matthew R Brier
    Program in Neuroscience, Division of Biological and Biomedical Science, School of Medicine, Washington University in St Louis, St Louis, MO, USA
    Neurobiol Aging 35:757-68. 2014
  7. pmc Resting state functional connectivity of the striatum in Parkinson's disease
    Carl D Hacker
    Department of Radiology, Washington University School of Medicine, Campus Box 8225, 4535 Scott Avenue, Saint Louis, MO 63110, USA
    Brain 135:3699-711. 2012
  8. pmc Functional connectivity in autosomal dominant and late-onset Alzheimer disease
    Jewell B Thomas
    Department of Neurology, Washington University in St Louis, St Louis, Missouri
    JAMA Neurol 71:1111-22. 2014
  9. pmc Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression
    Mathew R Brier
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 32:8890-9. 2012
  10. pmc Role of metabolic syndrome components in HIV-associated sensory neuropathy
    Beau M Ances
    Department of Neurology, Washington University, St Louis, 660 South Euclid Avenue, Box 8111, St Louis, MO 63110, USA
    AIDS 23:2317-22. 2009

Collaborators

Detail Information

Publications29

  1. pmc Combination antiretroviral therapy modulates the blood oxygen level-dependent amplitude in human immunodeficiency virus-seropositive patients
    Beau M Ances
    Department of Neurology, Washington University in St Louis, St Louis, MO 63110, USA
    J Neurovirol 14:418-24. 2008
    ..An increase in the BOLD fMRI response in HIV patients on low-CPE cART may reflect continued HIV replication in the CNS leading to increased oxidative stress and associated metabolic demands...
  2. pmc Alzheimer disease family history impacts resting state functional connectivity
    Liang Wang
    Department of Neurology, Washington University in Saint Louis, Saint Louis, MO 63110, USA
    Ann Neurol 72:571-7. 2012
    ..In particular, we determined whether a family history effect is detectable in apolipoprotein E (APOE) ε4 allele noncarriers...
  3. pmc Role of metabolic syndrome components in human immunodeficiency virus-associated stroke
    Beau M Ances
    Department of Neurology, Washington University in St Louis, St Louis, Missouri 63110, USA
    J Neurovirol 15:249-56. 2009
    ..Reducing MetS component levels in HIV+ patients could therefore protect them from subsequent stroke...
  4. pmc Pathways to neurodegeneration: effects of HIV and aging on resting-state functional connectivity
    Jewell B Thomas
    Department of Neurology, Washington University School of Medicine, St Louis, MO, USA
    Neurology 80:1186-93. 2013
    ..Resting-state functional connectivity MRI (rs-fcMRI) may provide insight into the neurophysiology of HIV and aging...
  5. pmc HIV and chronic methamphetamine dependence affect cerebral blood flow
    Beau M Ances
    Department of Neurology, Washington University in St Louis, 660 South Euclid Ave, Box 08111, St Louis, MO 63110, USA
    J Neuroimmune Pharmacol 6:409-19. 2011
    ..Abnormalities in CBF could serve as a surrogate measure for assessing the chronic effects of HIV and previous METH dependence on brain function...
  6. pmc Functional connectivity and graph theory in preclinical Alzheimer's disease
    Matthew R Brier
    Program in Neuroscience, Division of Biological and Biomedical Science, School of Medicine, Washington University in St Louis, St Louis, MO, USA
    Neurobiol Aging 35:757-68. 2014
    ..Only modularity was significantly affected by age. We also demonstrate that AD has a particular effect on hub-like regions in the brain. We conclude that AD causes large-scale disconnection that is present before onset of symptoms. ..
  7. pmc Resting state functional connectivity of the striatum in Parkinson's disease
    Carl D Hacker
    Department of Radiology, Washington University School of Medicine, Campus Box 8225, 4535 Scott Avenue, Saint Louis, MO 63110, USA
    Brain 135:3699-711. 2012
    ..We hypothesize that this gradient provides a clue to the pathogenesis of Parkinson's disease...
  8. pmc Functional connectivity in autosomal dominant and late-onset Alzheimer disease
    Jewell B Thomas
    Department of Neurology, Washington University in St Louis, St Louis, Missouri
    JAMA Neurol 71:1111-22. 2014
    ..Autosomal dominant Alzheimer disease (ADAD) is caused by rare genetic mutations in 3 specific genes in contrast to late-onset Alzheimer disease (LOAD), which has a more polygenetic risk profile...
  9. pmc Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression
    Mathew R Brier
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 32:8890-9. 2012
    ..These results provide insight into AD pathophysiology and reinforce an integrative view of the brain's functional organization...
  10. pmc Role of metabolic syndrome components in HIV-associated sensory neuropathy
    Beau M Ances
    Department of Neurology, Washington University, St Louis, 660 South Euclid Avenue, Box 8111, St Louis, MO 63110, USA
    AIDS 23:2317-22. 2009
    ..We examined whether MetS or its components predispose individuals to HIV-associated sensory neuropathy (HIV-SN)...
  11. pmc Weighted brain networks in disease: centrality and entropy in human immunodeficiency virus and aging
    Jewell B Thomas
    Department of Neurology, Washington University in St Louis, School of Medicine, St Louis, MO, USA
    Neurobiol Aging 36:401-12. 2015
    ..Graph models may allow us to distinguish previously indistinguishable effects related to HIV and age on FC...
  12. pmc Impaired default network functional connectivity in autosomal dominant Alzheimer disease
    Jasmeer P Chhatwal
    Department of Neurology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 81:736-44. 2013
    ....
  13. pmc Independent effects of HIV, aging, and HAART on brain volumetric measures
    Beau M Ances
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Acquir Immune Defic Syndr 59:469-77. 2012
    ..Neurocognitive impairment remains prevalent in HIV-infected (HIV+) individuals despite highly active antiretroviral therapy (HAART). We assessed the impact of HIV, HAART, and aging using structural neuroimaging...
  14. pmc Identifying risk factors for HIV-associated neurocognitive disorders using the international HIV dementia scale
    Sara Cross
    Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    J Neuroimmune Pharmacol 8:1114-22. 2013
    ..The IHDS should be further evaluated in large cohort HIV+ and HIV- populations in the United States, as there remains a significant need to identify an effective brief screening tool for cognitive impairment. ..
  15. pmc HIV-associated neurocognitive disorder
    David B Clifford
    Department of Neurology and Medicine, Washington University in St Louis, St Louis, MO, USA Electronic address
    Lancet Infect Dis 13:976-86. 2013
    ..Ultimately, the full control of virus in the brain is a necessary step in the goal of HIV eradication. ..
  16. pmc HIV-associated neurocognitive disorders and the impact of combination antiretroviral therapies
    Beau M Ances
    Department of Neurology, University of Washington, St Louis, MO 63130, USA
    Curr Neurol Neurosci Rep 8:455-61. 2008
    ..Because viral control generally has been successful without eliminating cognitive dysfunction, further clinical studies that assess adjunctive neuroprotective drugs are likely to be required...
  17. pmc Effects of HIV and combination antiretroviral therapy on cortico-striatal functional connectivity
    Mario Ortega
    aDepartment of Neurology bDepartment of Radiology cDepartment of Biomedical Engineering dDepartment of Microbiology eHope Center for Neurological Disorders, Washington University in St Louis, Missouri, USA
    AIDS 29:703-12. 2015
    ..Determine whether HIV and combination antiretroviral therapy (cART) affect resting-state functional connectivity (rs-fc) between the striatum and the cortical regions...
  18. pmc Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis
    Matthew R Brier
    1 Program in Neuroscience, Division of Biological and Biomedical Science, School of Medicine, Washington University in St Louis, St Louis, Missouri
    Brain Connect 4:299-311. 2014
    ..In conclusion, we propose a hypothesis regarding the development and spread of functional connectivity deficits seen in AD...
  19. pmc Comparison of regional cerebral blood flow responses to hypoglycemia using pulsed arterial spin labeling and positron emission tomography
    Ana Maria Arbelaez
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA
    PLoS ONE 8:e60085. 2013
    ..Compared to PET, PASL-MRI may provide a less invasive, less expensive method for assessing changes in rCBF during hypoglycemia without radiation exposure...
  20. pmc Diagnosis and evaluation of a patient with rapidly progressive dementia
    Robert C Bucelli
    Department of Neurology, Washington University School of Medicine, St Louis, USA
    Mo Med 110:422-8. 2013
    ..Identification of RPDs is important as some are treatable. This review focuses on the spectrum of RPDs, with special emphasis on paraneoplastic disorders and Creutzfeldt-Jakob disease (CJD)...
  21. ncbi request reprint Central nervous system complications of HIV infection
    Serena S Spudich
    Department of Neurology, Yale University, New Haven, CT, USA
    Top Antivir Med 19:48-57. 2011
    ..New data were presented on the potential importance of acute and early infection on the integrity of the central nervous system, complemented by studies of the effects of early treatment interventions...
  22. pmc Role of HIV in amyloid metabolism
    Mario Ortega
    Department of Neurology, School of Medicine, Washington University in St Louis, Box 8111, 660 South Euclid Ave, Saint Louis, MO, 63110, USA
    J Neuroimmune Pharmacol 9:483-91. 2014
    ..However, future longitudinal studies of older HIV + individuals using multiple modalities (including the combination of CSF markers and amyloid imaging) are necessary for investigating the effects of HIV on Aβ42 metabolism...
  23. pmc Impact of human immunodeficiency virus on neurocognition and risky behaviors in young adults
    Laurie M Baker
    Department of Psychology, University of Missouri Saint Louis, One University Blvd, Stadler 325, St Louis, MO, 62121, USA
    J Neurovirol 20:466-73. 2014
    ..However, there were no relationships between risky behavior and cognitive performance. Overall, our results suggest that HIV is associated with poorer cognition and increased risky behaviors in young adults...
  24. pmc An Eye on Brain Integrity: Acute Optic Neuritis Affects Resting State Functional Connectivity
    Gregory F Wu
    Department of Neurology, Washington University in St Louis School of Medicine, St Louis, Missouri, United States 2Department of Pathology and Immunology, Washington University in St Louis School of Medicine, St Louis, Missouri, United States
    Invest Ophthalmol Vis Sci 56:2541-6. 2015
    ..The purpose of this study was to determine the impact of acute optic neuritis (ON) on resting state functional connectivity magnetic resonance imaging (rs-fcMRI)...
  25. ncbi request reprint Advances in diagnostic testing for Alzheimer disease
    Suzanne E Schindler
    Knight Alzheimer s Disease Research Center, Washington University School of Medicine, St Louis, USA
    Mo Med 110:401-5. 2013
    ....
  26. pmc 11C-PiB imaging of human immunodeficiency virus-associated neurocognitive disorder
    Beau M Ances
    Department of Neurology, Washington University in St Louis, Campus Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Neurol 69:72-7. 2012
    ....
  27. pmc HIV infection and aging independently affect brain function as measured by functional magnetic resonance imaging
    Beau M Ances
    Department of Neurology, Washington University, St Louis, Missouri, USA
    J Infect Dis 201:336-40. 2010
    ..In the future, fMRI could be a noninvasive biomarker to assess HIV infection in the brain...
  28. ncbi request reprint Downbeating nystagmus and muscle spasms in a patient with glutamic-acid decarboxylase antibodies
    Beau M Ances
    Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Ophthalmol 140:142-4. 2005
    ..To report the ophthalmic findings and response to treatment in a patient with glutamic-acid decarboxylase antibodies...
  29. ncbi request reprint Coupling of changes in cerebral blood flow with neural activity: what must initially dip must come back up
    Beau M Ances
    Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cereb Blood Flow Metab 24:1-6. 2004
    ..Changes in CBF mediated by nitric oxide (NO) or other metabolites and not caused by a lack of O(2) or energy depletion most likely lead to an increased delivery of capillary O(2) in an attempt to maintain intracellular O(2) buffers...