Research Topics
| Anjali YadavaSummaryAffiliation: Walter Reed Army Medical Center Country: USA Publications
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Detail Information
Publications
Effect of codon optimization on expression levels of a functionally folded malaria vaccine candidate in prokaryotic and eukaryotic expression systemsAnjali Yadava
Department of Immunology, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
Infect Immun 71:4961-9. 2003..These antibodies recognize EBA-175 present on merozoites as well as in sporozoites by immunofluorescence. Our results suggest that the Pichia-based EBA-F2 vaccine construct has further potential to be developed for clinical use...
Evaluation of the safety and immunogenicity in rhesus monkeys of a recombinant malaria vaccine for Plasmodium vivax with a synthetic Toll-like receptor 4 agonist formulated in an emulsionJoanne M Lumsden
Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA
Infect Immun 79:3492-500. 2011..We conclude that the combination of VMP001 and GLA-SE is safe and immunogenic in monkeys and may serve as a potential second-generation vaccine candidate against P. vivax malaria...
Cross-species immunity following immunization with a circumsporozoite protein-based vaccine for malariaAnjali Yadava
Malaria Vaccine Branch, United States Military Malaria Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
J Infect Dis 205:1456-63. 2012..In addition, we report that vaccination of mice with VMP001, a P. vivax CSP vaccine candidate, reduces, not enhances, P. berghei infection in mice...
A novel chimeric Plasmodium vivax circumsporozoite protein induces biologically functional antibodies that recognize both VK210 and VK247 sporozoitesAnjali Yadava
Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
Infect Immun 75:1177-85. 2007..These results strongly suggest that recombinant CS is biologically active and highly immunogenic across major histocompatibility complex strains and raises the prospect that in humans this vaccine may induce protective immune responses...
Evaluation of immune responses to a Plasmodium vivax CSP-based recombinant protein vaccine candidate in combination with second-generation adjuvants in miceJoanne M Lumsden
Malaria Vaccine Branch United States, Military Malaria Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States
Vaccine 30:3311-9. 2012..Based on these results, we conclude that the combination of VMP001 and GLA-SE is highly immunogenic in mice and may serve as a potential second-generation vaccine candidate against vivax malaria...
Process development for the production of an E. coli produced clinical grade recombinant malaria vaccine for Plasmodium vivaxBrian A Bell
Pilot BioProduction Facility, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States
Vaccine 27:1448-53. 2009....
Positive rK39 serologic assay results in US servicemen with cutaneous leishmaniasisJoshua D Hartzell
Infectious Diseases Division, Walter Reed Army Medical Center, Washington, District of Columbia 20307, USA
Am J Trop Med Hyg 79:843-6. 2008..2% and 28.8% had positive results, respectively. CL is associated with a reactive rK39 assay result in some patients without clinical evidence of VL...
Genome-wide expression profiling in malaria infection reveals transcriptional changes associated with lethal and nonlethal outcomesKurt Schaecher
Department of Immunology, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA
Infect Immun 73:6091-100. 2005....
